Algic MR 100mg/8mg Tablet: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit, or black tarry stools.
- Severe abdominal pain or persistent indigestion.
- Chest pain, shortness of breath, or difficulty breathing.
- Sudden swelling of face, lips, or throat.
- Yellowing of skin or eyes, or dark urine.
- Decreased urine output or swelling in legs.
- Severe headache with visual changes or confusion.
- Unusual bruising or bleeding from gums or nose.
If experiencing severe symptoms, call emergency services immediately.
What is acelive th 100mg/8mg tablet used for?
This medicine is a combination of Aceclofenac (100 mg) and Thiocolchicoside (8 mg) used for short-term relief of acute musculoskeletal pain and muscle spasm. It works by reducing inflammation and relaxing muscles. It should be taken with food, usually twice daily, and is not recommended for long-term use or during pregnancy.
- Generic Name: Aceclofenac (100mg) + Thiocolchicoside (8mg)
- Manufacturer: Yodley Life Sciences Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acelive th 100mg/8mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफ्लोफेनाक 100 मिलीग्राम और थायोकोल्चिकोसाइड 8 मिलीग्राम का संयोजन है। इसका उपयोग तीव्र मस्कुलोस्केलेटल दर्द और मांसपेशियों की ऐंठन के अल्पकालिक उपचार के लिए किया जाता है, जैसे कमर दर्द, गर्दन दर्द, और मोच। यह दर्द और सूजन को कम करने के साथ-साथ मांसपेशियों को आराम देती है। इसे भोजन के साथ लेना चाहिए और डॉक्टर की सलाह के बिना लंबे समय तक नहीं लेना चाहिए। गर्भावस्था और स्तनपान के दौरान इसका उपयोग नहीं करना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति, और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें, आमतौर पर भोजन के साथ। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की समस्या का खतरा बढ़ सकता है। यदि आपको पेट अल्सर, गुर्दे या यकृत की बीमारी, हृदय रोग, या अस्थमा है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान इसका उपयोग न करें। बच्चों को न दें। दवा को ठंडी और सूखी जगह पर रखें।
💊 acelive th 100mg/8mg tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain with muscle spasm","description":"Relieves pain and reduces muscle spasm in conditions such as acute low back pain, neck pain, and myofascial pain syndrome.","evidence":"Well-established for short-term use"},{"condition":"Post-traumatic pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling","description":"Used after sprains, strains, and soft tissue injuries to reduce inflammation and pain.","evidence":"Commonly used, evidence supports short-term relief"},{"condition":"Post-operative pain","description":"May be prescribed for short-term management of pain and muscle spasm after certain surgeries.","evidence":"Limited to short-term use under medical supervision"},{"condition":"Osteoarthritis flare-up","description":"Provides symptomatic relief during acute painful episodes of osteoarthritis, but not for long-term disease modification.","evidence":"Symptomatic relief established for short-term use"}]
Off-label uses: [{"condition":"Tension-type headache with muscle spasm","description":"Sometimes prescribed off-label when muscle tension contributes to headache, but not a first-line treatment.","evidence":"Limited"},{"condition":"Dysmenorrhea with muscle spasm","description":"Occasionally used off-label for painful menstrual cramps, but NSAIDs alone are usually preferred.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain with muscle spasm
Also treats: Low back pain, Neck pain, Osteoarthritis flare-up, Post-traumatic pain, Post-operative pain
📋 Drug Information
| Generic Name(s) | Aceclofenac (100mg) + Thiocolchicoside (8mg) |
| Brand Name | acelive th 100mg/8mg tablet |
| Manufacturer | Yodley Life Sciences Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container, tightly closed. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the production of prostaglandins that cause pain, inflammation, and fever. Thiocolchicoside is a centrally acting muscle relaxant that binds to GABA-A receptors and glycine receptors in the spinal cord and brainstem, enhancing inhibitory neurotransmission and reducing muscle spasm. Together, they address both the inflammatory pain and the muscle spasm component of musculoskeletal conditions.
Mechanism Steps
💡 How to Take acelive th 100mg/8mg tablet
Strength: Tablet containing Aceclofenac 100 mg and Thiocolchicoside 8 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally twice daily, preferably with food. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. Do not self-medicate or exceed the prescribed dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function and overall health status. |
| Renal Impairment | Use with caution in patients with mild to moderate renal impairment. Dose reduction may be necessary. This medicine is contraindicated in severe renal impairment (creatinine clearance <30 mL/min). Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | Use with caution in patients with mild to moderate hepatic impairment. Dose reduction may be necessary. This medicine is contraindicated in severe hepatic impairment. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily (i.e., 200 mg aceclofenac and 16 mg thiocolchicoside per day). Do not exceed this dose unless specifically instructed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acelive th 100mg/8mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors/ARBs/Diuretics | Moderate | |
| SSRIs | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin and other anticoagulants
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- SSRIs
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulceration, and liver damage when combined with aceclofenac. It may also enhance the drowsiness caused by thiocolchicoside.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to aceclofenac, thiocolchicoside, or any component of the formulation.","Active or history of recurrent peptic ulcer, gastrointestinal bleeding, or perforation.","Severe heart failure, ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease.","Severe liver impairment or active liver disease.","Severe kidney impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["Take with food to reduce gastrointestinal irritation.","Avoid concurrent use with other NSAIDs, including selective COX-2 inhibitors.","Use with caution in the elderly, who are at higher risk of side effects.","Monitor for signs of gastrointestinal bleeding, especially in patients with a history of ulcers.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for longer than necessary; the lowest effective dose for the shortest duration is recommended.","Inform your doctor if you have asthma, as NSAIDs can trigger bronchospasm.","Avoid alcohol consumption while taking this medicine.","Use with caution in patients with dehydration or volume depletion.","Not recommended for children and adolescents under 18 years."]
🤱 Lactation Safety
It is not known whether aceclofenac and thiocolchicoside pass into breast milk. Due to the lack of data, this medicine is not recommended during breastfeeding. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, dizziness, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if taken recently. Monitor vital signs, kidney and liver function, and manage complications as they arise.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually with food to minimize stomach upset. Do not take more than the recommended dose or use it for longer than advised. Avoid alcohol while taking this medicine because it can increase the risk of stomach bleeding and liver problems. Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma. Do not take other pain relievers or NSAIDs without consulting your doctor, as this can increase the risk of side effects. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep out of reach of children. Store at room temperature away from moisture and direct sunlight. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose; do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events when taking NSAIDs like aceclofenac. They may also be more sensitive to the drowsiness caused by thiocolchicoside. Use the lowest effective dose for the shortest duration, and monitor kidney and liver function regularly. Avoid concurrent use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended for women who are trying to conceive or are pregnant. NSAIDs like aceclofenac may interfere with ovulation and increase the risk of miscarriage or fetal complications. If you are planning pregnancy, consult your doctor to switch to a safer alternative for pain management. Use effective contraception while taking this medicine if you are of childbearing age.
🏥 Post-Surgery Considerations
This medicine may be prescribed for short-term pain management after surgery, but it should be used with caution due to the risk of bleeding and kidney problems. Inform your surgeon and anesthesiologist about all medicines you are taking. Do not use it for prolonged periods after surgery without medical supervision.
🦷 Dental Procedures
If you are scheduled for dental procedures, inform your dentist that you are taking this medicine. NSAIDs can increase the risk of bleeding during and after dental surgery. Your dentist may advise you to stop the medicine temporarily or take precautions. Do not stop the medicine without consulting your prescribing doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience drowsiness or dizziness. Avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medicine affects you. Gentle stretching and low-impact exercises may be beneficial, but avoid strenuous activities that could worsen your condition. Consult your physiotherapist for a tailored exercise plan.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. If your job involves heavy lifting or physical strain, consult your doctor about modifications. Most people can continue their usual activities with caution.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience any serious side effects such as severe stomach pain, black stools, allergic reactions, or signs of liver or kidney problems. Do not stop abruptly if you have been taking it for a long time without consulting your doctor. Usually, this medicine is prescribed for a short duration, and you should stop after the prescribed course unless your doctor advises otherwise.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney problems, liver damage, and cardiovascular events. It is not recommended for extended use. If you need pain relief for more than a few days, consult your doctor to explore safer long-term options and monitor your kidney and liver function periodically.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve muscle strength and flexibility.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and muscle spasm.
Evidence: Commonly used, evidence supports symptomatic reliefMay help relieve certain types of musculoskeletal pain.
Evidence: Limited, but some studies show benefitCreams or gels containing NSAIDs or capsaicin can provide local pain relief with fewer systemic side effects.
Evidence: Well-established for localized pain💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking. It is generally safe to receive vaccines while on this medicine, but consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually to maintain consistent relief, but consult your doctor for specific advice. Keep enough supply for your entire trip. Check local customs regulations regarding prescription medicines before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Aceclofenac starts relieving pain within 30 to 60 minutes, while the muscle relaxant effect may take a few hours. You may notice significant improvement within 1-2 days.
A: No, it should be taken with food to reduce the risk of stomach irritation and bleeding.
A: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects and should be avoided unless specifically advised by your doctor.
A: No, alcohol should be avoided as it increases the risk of stomach bleeding and liver problems.
A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for acelive th 100mg/8mg tablet
View AllAlternative brands with exact same active ingredient:
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edoclof-max tabletEdmund Healthcare ₹32.81 86% CHEAPER
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xynac th 100mg/8mg tabletArlak Biotech Pvt Ltd ₹67.50 71.2% CHEAPER
-
Thiochy A 100mg/8mg TabletMelody Healthcare Private Limited ₹92.81 60.4% CHEAPER
-
Thiodal 100mg/8mg TabletSapiens Labs Pvt Ltd ₹105.00 55.2% CHEAPER
-
thioceclo 100mg/8mg tablet srAristo Pharmaceuticals Pvt Ltd ₹128.30 45.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: This medicine is specifically for musculoskeletal pain with muscle spasm and is not effective for all types of pain, such as headache or fever. - Myth: It is safe to take this medicine for months.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects and should be avoided unless specifically advised by a doctor. - Myth: You can take this medicine on an empty stomach.
Fact: Taking this medicine with food is important to reduce the risk of stomach irritation and bleeding. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 100 mg + Thiocolchicoside 8 mg tablet (generic)
Brand Alternatives
- Algic MR 100mg/8mg Tablet