acebrodak-dm tablet sr - Acebrophylline (200mg) + Desloratadine (5mg) medicine

acebrodak-dm tablet sr - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Devak Formulations ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is acebrodak-dm tablet sr used for?

Abmac Tablet (Acebrophylline + Desloratadine) is used to treat RESPIRATORY. It contains Acebrophylline (200mg) + Desloratadine (5mg), which Acebrophylline: Bronchodilator and mucolytic; Desloratadine: H1-receptor antagon. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Acebrophylline + Desloratadine
  • Manufacturer: Devak Formulations
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š acebrodak-dm tablet sr Uses & Benefits

Allergic rhinitis, asthma, COPD.

Off-label uses: Urticaria, chronic cough.

๐Ÿ“‹ Drug Information

Generic Name(s)Acebrophylline + Desloratadine
Brand NameAbmac Tablet
ManufacturerDevak Formulations
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassRespiratory
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAcebrophylline: Well absorbed orally; Desloratadine: Well absorbed orally.
DistributionAcebrophylline: Distributed widely; Desloratadine: Distributed widely, crosses blood-brain barrier minimally.
Protein BindingAcebrophylline: ~50%; Desloratadine: 82-87%.
MetabolismAcebrophylline: Hepatic via CYP450; Desloratadine: Hepatic via CYP2C8 and CYP3A4.
Half-LifeAcebrophylline: ~8 hours; Desloratadine: ~27 hours.
ExcretionAcebrophylline: Renal (70% unchanged); Desloratadine: Renal and fecal.
BioavailabilityAcebrophylline: ~100%; Desloratadine: ~40%.
Onset of ActionAcebrophylline: 1-2 hours; Desloratadine: 1-3 hours.
Peak Plasma TimeAcebrophylline: 2-4 hours; Desloratadine: 3-4 hours.
Duration of ActionAcebrophylline: 12 hours; Desloratadine: 24 hours.

How It Works

Acebrophylline: Bronchodilator and mucolytic; Desloratadine: H1-receptor antagonist.

Mechanism Steps

1Acebrophylline inhibits phosphodiesterase, increasing cAMP levels.
2Acebrophylline blocks adenosine receptors, reducing bronchoconstriction.
3Acebrophylline reduces mucus viscosity by breaking disulfide bonds.

๐Ÿ’ก How to Take acebrodak-dm tablet sr

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acebrodak-dm tablet sr

โœ… Common Side Effects

  • Headache
  • Dry mouth
  • Fatigue
  • Nausea

๐Ÿšจ Serious Side Effects

  • Hypersensitivity reactions
  • Hepatotoxicity
  • Cardiac arrhythmias

โš ๏ธ Rare Side Effects

  • Seizures
  • Thrombocytopenia
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Moderate Increased desloratadine levels
Erythromycin Moderate Increased desloratadine levels
Fluoxetine Moderate Increased desloratadine levels
Cimetidine Minor Increased acebrophylline levels
Alcohol Minor Increased sedation

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors
  • CYP2C8 inhibitors
  • Monoamine oxidase inhibitors

โšก Moderate Interactions

  • Ketoconazole
  • Erythromycin
  • Fluoxetine

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Alcohol

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase desloratadine levels.

๐Ÿท Alcohol Interaction

May increase sedation risk.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe hepatic impairment.

๐Ÿ“Š Monitoring Parameters

Respiratory function, liver function, cardiac monitoring if high risk.

๐Ÿคฑ Lactation Safety

Caution advised; desloratadine excreted in breast milk.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; no specific antidote.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

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