ace 100mg tablet - Aceclofenac (100mg) medicine

Aceclofenac 100mg Tablet: Complete Guide to Uses, Dosage, and Safety

No reviews yet
Aceclofenac (100mg)
🏭 Jackson Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and prescribed by a doctor. Avoid in the third trimester due to risk of premature closure of ductus arteriosus. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term use in approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is ace 100mg tablet used for?

Aceclofenac 100mg is an NSAID used to relieve pain and inflammation in conditions like arthritis and musculoskeletal injuries. It works by blocking COX enzymes and is taken twice daily with food.

  • Generic Name: Aceclofenac
  • Manufacturer: Jackson Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ace 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से दर्द और सूजन को कम करने के लिए इस्तेमाल की जाती है। यह गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), कमर दर्द, मांसपेशियों की चोट, और मासिक धर्म के दर्द में राहत देती है। यह सूजन को कम करके जोड़ों की अकड़न और दर्द में आराम पहुंचाती है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, पेट दर्द, अपच, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, लीवर की क्षति, और एलर्जी प्रतिक्रिया हो सकती है। यदि काला मल, खून की उल्टी, सांस लेने में कठिनाई, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन बिल्कुल न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ जाता है। डॉक्टर की सलाह के बिना लंबे समय तक इसका सेवन न करें। गर्भवती महिलाएं, स्तनपान कराने वाली माताएं, और गुर्दे या लीवर की बीमारी वाले मरीज डॉक्टर से परामर्श करें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 ace 100mg tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in joints, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint inflammation and pain, but does not halt disease progression.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with this inflammatory condition.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"Used for short-term relief of pain and swelling in sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"May be used for short-term management of mild to moderate post-surgical pain.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Effective in relieving menstrual cramps and associated pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Renal colic","description":"Occasionally used for pain relief in kidney stones, but not first-line.","evidence":"Limited"}]

Primary treatment for: Osteoarthritis

Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal injuries, Dysmenorrhea

📋 Drug Information

Generic Name(s)Aceclofenac
Brand NameAceclo Tablet
ManufacturerJackson Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach irritation.
2
Do not exceed the prescribed dose or duration without consulting your doctor.
3
Avoid alcohol completely while taking this medicine.
4
Inform your doctor if you have a history of stomach ulcers, kidney, liver, or heart disease.
5
Do not take other NSAIDs or blood thinners without medical advice.
6
If you experience black stools, vomiting blood, or severe abdominal pain, seek immediate medical help.
7
Use the lowest effective dose for the shortest possible time.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Acute muscle injury
Used for short-term relief of pain and swelling.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration. Food may slightly delay absorption but does not significantly reduce the extent of absorption.
DistributionIt is highly bound to plasma proteins and distributes well into synovial fluid, which is beneficial for joint conditions.
Protein BindingGreater than 99% bound to plasma proteins, primarily albumin.
MetabolismIt is extensively metabolized in the liver, mainly by cytochrome P450 enzymes, to several metabolites.
Half-LifeThe elimination half-life is approximately 3 to 4 hours.
ExcretionMetabolites are excreted primarily in urine and to a lesser extent in feces.
BioavailabilityThe oral bioavailability is approximately 80-100%.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentration is reached about 1.5 to 2 hours after ingestion.
Duration of ActionThe analgesic effect lasts for about 4 to 6 hours, so it is usually taken twice daily.

How It Works

This medicine works by inhibiting the cyclooxygenase (COX) enzymes, primarily COX-2, which are responsible for converting arachidonic acid into prostaglandins. Prostaglandins are chemical messengers that mediate pain, inflammation, and fever. By blocking their production, this medicine reduces pain and swelling. It also has some effect on COX-1, which can lead to gastrointestinal side effects.

Mechanism Steps

1
Absorption and distribution: After oral intake, this medicine is absorbed and distributed to inflamed tissues.
2
COX enzyme inhibition: It reversibly inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
3
Reduced prostaglandin synthesis: This leads to decreased levels of prostaglandins, which are key mediators of pain and inflammation.
4
Analgesic and anti-inflammatory effect: The result is relief from pain, swelling, and stiffness in affected joints and tissues.

💡 How to Take ace 100mg tablet

Strength: Aceclofenac 100mg immediate-release tablet

1Swallow the tablet whole with a glass of water.
2Take it with food or milk to reduce stomach upset.
3Do not crush, chew, or break the tablet.
4Take at the same times each day.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100mg taken orally twice daily, preferably with food. The dose may be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Do not exceed 200mg per day. For acute conditions, the lowest effective dose for the shortest duration should be used.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Monitor kidney function closely.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing.
Maximum Daily Dose200mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ace 100mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Stomach pain or indigestion (Common (5-10%))
Take with meals. Avoid spicy foods. Consult doctor if severe.
Headache (Common (5-10%))
Usually resolves. Stay hydrated. Consult if severe or persistent.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how it affects you.
Skin rash (Uncommon (1-5%))
Stop the medicine and consult your doctor if rash appears.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black tarry stools, vomiting blood, or severe abdominal pain.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor immediately.
Liver toxicity (Rare (<0.1%))
Seek medical help if you develop yellowing of eyes or skin, dark urine, or severe nausea.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.
Cardiovascular events (heart attack, stroke) (Rare (<0.1%))
Seek immediate care for chest pain, shortness of breath, or sudden weakness on one side.

⚠️ Rare Side Effects

Severe skin reactions such as Stevens-Johnson syndrome
Aseptic meningitis
Pancreatitis
Hepatitis
Acute renal failure
Interstitial nephritis
Heart failure exacerbation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
ACE inhibitors Moderate
Diuretics Moderate
Lithium Moderate
SSRIs Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Other NSAIDs
  • Corticosteroids
  • Methotrexate

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Lithium
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of stomach bleeding and ulcers.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney disease","Severe liver disease","Aspirin-sensitive asthma","Third trimester of pregnancy","Allergy to aceclofenac or other NSAIDs","Coronary artery bypass graft surgery (peri-operative period)"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol.","Do not use with other NSAIDs.","Use with caution in elderly.","Monitor kidney and liver function during long-term use.","May impair ability to drive or operate machinery.","Stop before surgery as advised by your doctor."]

🤱 Lactation Safety

This medicine may pass into breast milk. Consult your doctor before use. Generally not recommended unless clearly needed.

💊 Overdose Management

Overdose may cause nausea, vomiting, stomach pain, dizziness, and in severe cases, kidney failure or seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be given if within 1-2 hours of ingestion. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding. Do not use this medicine if you have a history of stomach ulcers, severe kidney or liver disease, or heart failure. Inform your doctor about all other medicines you are taking, especially blood thinners, steroids, antidepressants, and blood pressure medicines. Do not take other NSAIDs concurrently. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Regular monitoring of kidney and liver function may be needed during long-term use. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

Avoid this medicine if you are planning pregnancy or are pregnant, especially in the third trimester, unless clearly advised by your doctor. Discuss alternative pain relief options.

🏥 Post-Surgery Considerations

This medicine may increase bleeding risk. Inform your surgeon if you are taking it. It may need to be stopped before surgery as advised.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase bleeding during dental procedures. Your dentist may advise stopping it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or cycling.
😴
Practice good posture and ergonomics.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables.
🧘
Get adequate sleep to aid recovery.
🌞
Avoid smoking and limit alcohol.

🏋️ Exercise Considerations

Avoid high-impact exercises that strain joints. Consult a physiotherapist for safe exercises. Stop if pain worsens.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce processed and fried foods.
Stay well hydrated.
Eat plenty of fruits and vegetables rich in antioxidants.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so plan meals accordingly.

🛑 When to Stop This Medicine

Stop this medicine and consult your doctor if you experience severe side effects such as stomach pain, black stools, allergic reactions, or if your pain persists beyond the prescribed duration. Do not stop abruptly if you are on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function, blood pressure, and blood counts is advised. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Topical NSAIDs

May provide local relief with fewer systemic side effects.

Evidence: Well-established
Heat and cold therapy

Helps reduce stiffness and pain temporarily.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Declare it at customs if required. Keep enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old woman with rheumatoid arthritis
Used this medicine for flare-ups along with her regular disease-modifying therapy. She experienced good pain relief but had to stop after 10 days due to mild stomach discomfort. Her doctor advised taking it with food and using gastroprotection.
💡 Lesson: Short-term use with food and gastroprotection can minimize side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe for long-term use?

A: Long-term use should be under medical supervision due to potential risks to the stomach, kidneys, liver, and heart.

Q: Can I take it with paracetamol?

A: Yes, but only if prescribed by your doctor. Do not self-combine.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ace 100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Aceclofenac is an antibiotic.
    Fact: Aceclofenac is a painkiller and anti-inflammatory medicine, not an antibiotic.
  • Myth: It can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset.
  • Myth: It is safe to take indefinitely.
    Fact: Long-term use requires medical supervision due to risks of kidney, liver, and heart problems.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 100mg tablet (generic)

Brand Alternatives

  • Aceclo
  • Aceclo SP
  • Zerodol
  • Hifenac
  • Aceproxyvon

📊 Comparison with Similar Medicines

[{"medicine":"Aceclofenac","class":"NSAID","half_life":"3-4 hours","common_use":"Arthritis, musculoskeletal pain"},{"medicine":"Diclofenac","class":"NSAID","half_life":"1-2 hours","common_use":"Arthritis, acute pain"},{"medicine":"Ibuprofen","class":"NSAID","half_life":"2 hours","common_use":"Pain, fever, inflammation"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory