Accetiz 100 mg/2 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe dizziness or fainting
- Persistent high fever
If experiencing severe symptoms, call emergency services immediately.
What is accetiz 100 mg/2 mg tablet used for?
This medicine is a combination of aceclofenac (an NSAID) and tizanidine (a muscle relaxant) used for short-term relief of painful musculoskeletal conditions with muscle spasm. It is taken orally with food, usually one tablet once or twice daily, and must be prescribed by a doctor.
- Generic Name: Aceclofenac + Tizanidine
- Manufacturer: Geno Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 accetiz 100 mg/2 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफेनाक और टिज़ानिडीन का संयोजन है, जिसका उपयोग मांसपेशियों में दर्द, सूजन और ऐंठन के इलाज के लिए किया जाता है। यह आमतौर पर कमर दर्द, गर्दन दर्द, मोच और मांसपेशियों की अकड़न में राहत देने के लिए दी जाती है। यह दवा दर्द और सूजन को कम करने के साथ-साथ मांसपेशियों को आराम देती है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना, नींद आना, मुंह सूखना और थकान शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, एलर्जी, लीवर और किडनी की समस्या हो सकती है। अगर आपको काला मल, खून की उल्टी, त्वचा या आंखों का पीलापन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब बिल्कुल न लें। दवा लेने के बाद गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद और चक्कर आ सकते हैं। अपने डॉक्टर को अपनी सभी बीमारियों और दवाओं के बारे में बताएं। डॉक्टर की सलाह के बिना दवा की खुराक न बढ़ाएं और न ही इसे लंबे समय तक लें।
💊 accetiz 100 mg/2 mg tablet Uses & Benefits
[{"condition":"Acute low back pain with muscle spasm","description":"This medicine provides short-term relief of pain and reduces muscle spasm associated with acute lumbar strain or disc-related back pain.","evidence":"Well-established"},{"condition":"Neck pain and cervical muscle spasm","description":"Used to relieve pain and stiffness in the neck caused by muscle spasm or minor injuries.","evidence":"Moderate"},{"condition":"Musculoskeletal sprains and strains","description":"Helps reduce pain, inflammation, and associated muscle spasm after soft tissue injuries.","evidence":"Moderate"},{"condition":"Post-operative pain with muscle spasm","description":"Sometimes prescribed after orthopedic or soft tissue surgery to manage pain and spasm.","evidence":"Limited"},{"condition":"Osteoarthritis flare with muscle spasm","description":"Provides symptomatic relief when joint pain is accompanied by secondary muscle spasm.","evidence":"Limited"}]
Off-label uses: [{"condition":"Tension-type headache with neck muscle spasm","description":"Occasionally prescribed off-label when headache is associated with significant neck muscle tightness.","evidence":"Limited"},{"condition":"Fibromyalgia pain","description":"Rarely used off-label for short-term relief of muscle pain in fibromyalgia, but evidence is weak.","evidence":"Insufficient"}]
Primary treatment for: Musculoskeletal pain with muscle spasm
Also treats: Acute low back pain, Neck pain, Sprains and strains, Osteoarthritis flare
📋 Drug Information
| Generic Name(s) | Aceclofenac + Tizanidine |
| Brand Name | Accetiz 100 mg/2 mg tablet |
| Manufacturer | Geno Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Muscle Relaxant |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase enzymes COX-1 and COX-2, reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Tizanidine is a centrally acting alpha-2 adrenergic agonist that reduces the release of excitatory neurotransmitters from spinal interneurons, thereby decreasing muscle tone and spasm. Together, they address both the inflammatory pain component and the muscle spasm component of musculoskeletal conditions.
Mechanism Steps
💡 How to Take accetiz 100 mg/2 mg tablet
Strength: Each tablet contains aceclofenac 100 mg and tizanidine 2 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally one to two times daily, preferably with food. The exact dose and duration depend on the condition being treated, its severity, and the patient's response. The maximum recommended daily dose is generally two tablets in divided doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients above 65 years may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and kidney problems. The dose may need to be reduced, and kidney function should be monitored. Use with caution and under medical supervision. |
| Renal Impairment | Dose adjustment is required in patients with kidney impairment. In mild to moderate kidney impairment, the dose may be reduced. In severe kidney impairment (eGFR <30 mL/min), this medicine is contraindicated. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Dose adjustment is required in patients with liver impairment. In mild to moderate liver impairment, the dose may be reduced. In severe liver impairment, this medicine is contraindicated. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 tablets (aceclofenac 200 mg + tizanidine 4 mg) in divided doses. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of accetiz 100 mg/2 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ciprofloxacin | Major | |
| Fluvoxamine | Major | |
| Other NSAIDs | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| Antihypertensives | Moderate | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Ciprofloxacin
- Fluvoxamine
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (e.g., ACE inhibitors, ARBs)
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- Corticosteroids
- SSRIs
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver damage associated with aceclofenac. It also enhances the sedative and blood pressure-lowering effects of tizanidine, leading to excessive drowsiness, dizziness, and risk of falls.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney disease (eGFR
⚠️ Warnings & Precautions
["Take with food to reduce gastrointestinal irritation.","Avoid alcohol completely while taking this medicine.","Do not drive or operate machinery until you know how this medicine affects you.","Use with caution in the elderly due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma.","Do not take other NSAIDs or pain relievers without consulting your doctor.","Use the lowest effective dose for the shortest duration possible.","Do not stop suddenly if you have been on long-term therapy; consult your doctor.","Monitor for signs of bleeding, especially if taking blood thinners.","Report any unusual symptoms such as yellowing of eyes, dark urine, or severe fatigue."]
🤱 Lactation Safety
Not established from the available information. Aceclofenac and tizanidine may pass into breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor after weighing the benefits and risks.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, dizziness, low blood pressure, nausea, vomiting, stomach pain, and in severe cases, liver or kidney damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be given if the patient presents early. Monitor vital signs, liver and kidney function, and provide supportive care as needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine with food or a glass of milk to reduce the risk of stomach irritation. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Avoid alcohol completely while taking this medicine because it increases the risk of stomach bleeding and liver problems. Do not drive or operate heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Do not take other pain relievers, especially other NSAIDs, without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart problems, or asthma. Use the lowest effective dose for the shortest duration possible. Do not stop this medicine suddenly if you have been taking it for a long time; consult your doctor for a tapering plan. Keep all follow-up appointments and get regular blood tests if advised. Store this medicine in its original container away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients above 65 years are at higher risk of side effects such as gastrointestinal bleeding, kidney impairment, drowsiness, and dizziness. The dose may need to be reduced, and kidney function should be monitored regularly. Use with caution and avoid long-term use unless clearly necessary.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like aceclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Tizanidine is not recommended during pregnancy. Discuss alternative pain management options with your doctor.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to manage pain and muscle spasm. However, it should be used with caution as it can increase the risk of bleeding and kidney problems. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery. Follow your doctor's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. NSAIDs can increase the risk of bleeding during dental work. Your dentist may advise you to stop the medicine temporarily or take precautions. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous exercise or heavy lifting as it may worsen muscle spasm or cause injury. Gentle stretching and low-impact activities like walking or swimming may be beneficial, but consult your doctor before starting any exercise program. Stop immediately if you experience pain, dizziness, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and fatigue, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is advisable to avoid such activities until you know how the medicine affects you. Office workers may need to take frequent breaks and maintain good posture. Inform your employer if your job involves operating heavy equipment.
🛑 When to Stop This Medicine
Stop taking this medicine if your doctor advises you to, or if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or signs of liver or kidney problems. Do not stop suddenly if you have been taking it for a long time; consult your doctor for a tapering plan. If your pain and spasm have resolved, consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney impairment, liver injury, and cardiovascular events. Regular monitoring of kidney and liver function, blood pressure, and complete blood count may be required. It is not recommended for extended use without medical supervision. If long-term therapy is needed, the doctor may consider alternative treatments or add gastroprotective agents.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and muscle spasm.
Evidence: Well-establishedMay help relieve muscle spasm and pain.
Evidence: ModerateSome evidence for chronic pain relief.
Evidence: LimitedCan improve flexibility and reduce muscle tension.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking. It is generally safe to receive vaccines while on this medicine, but consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations regarding prescription medicines before travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it with food. The muscle relaxant effect also begins within about 30 to 60 minutes.
A: No, it is best to take this medicine with food or milk to reduce the risk of stomach irritation and ulcers.
A: This medicine can cause drowsiness and dizziness. Avoid driving or operating heavy machinery until you know how it affects you.
A: No, alcohol should be completely avoided while taking this medicine as it increases the risk of stomach bleeding, liver problems, and excessive drowsiness.
A: This medicine is intended for short-term use only, usually for a few days to a week. Long-term use should only be under medical supervision with regular monitoring.
🤔 Common Patient Concerns
🔄 Substitutes for accetiz 100 mg/2 mg tablet
View AllAlternative brands with exact same active ingredient:
-
solo mr 100mg/2mg tabletDaksh Pharma Pvt Ltd ₹45.00 20% COSTLIER
-
starnac tz 100mg/2mg tabletInvision Medi Sciences Pvt Ltd ₹45.94 22.5% COSTLIER
-
starmoto-tz 100mg/2mg tabletMinova Life Sciences Pvt Ltd ₹45.94 22.5% COSTLIER
-
zofen-t 100mg/2mg tabletZodak Healthcare ₹48.00 28% COSTLIER
-
tizanac ac 100mg/2mg tabletMDC Pharmaceuticals Pvt Ltd ₹53.44 42.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of kidney, liver, and heart problems. - Myth: It is safe to take this medicine on an empty stomach.
Fact: Taking it on an empty stomach increases the risk of stomach irritation and ulcers. Always take it with food. - Myth: This medicine is a sleeping pill.
Fact: Tizanidine can cause drowsiness, but this medicine is not a sleeping pill. It is a muscle relaxant and pain reliever. - Myth: I can stop this medicine whenever I want.
Fact: If you have been taking it for a long time, stopping suddenly may cause withdrawal symptoms. Consult your doctor for a tapering plan.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 100 mg + Tizanidine 2 mg tablet (generic)
Brand Alternatives
- Accetiz 100 mg/2 mg tablet