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acarsafe 50 tablet - Acarbose (50mg) medicine

Acarsafe 50 Tablet - Uses, Price, Side Effects

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Acarbose (50mg)
๐Ÿญ Biochem Pharmaceutical Industries ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is acarsafe 50 tablet used for?

Acarsafe 50 Tablet contains Acarbose 50mg, an alpha-glucosidase inhibitor used to treat type 2 diabetes. It works by slowing down the digestion of carbohydrates in the intestines, thereby preventing sharp spikes in blood sugar levels after meals. It is often prescribed alongside diet and exercise to improve glycemic control.

  • Generic Name: Acarbose
  • Manufacturer: Biochem Pharmaceutical Industries
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š acarsafe 50 tablet Uses & Benefits

Type 2 diabetes mellitus (as monotherapy or adjunct to diet and exercise, or in combination with other antidiabetic agents).

Off-label uses: Postprandial hyperglycemia in type 1 diabetes (limited data); dumping syndrome; obesity (investigational).

๐Ÿ“‹ Drug Information

Generic Name(s)Acarbose
Brand NameAcartex 50 Tablet
ManufacturerBiochem Pharmaceutical Industries
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassAlpha-glucosidase inhibitors
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionPoorly absorbed; less than 2% of oral dose is absorbed as active drug.
DistributionMinimal systemic distribution; primarily acts locally in the gastrointestinal tract.
Protein BindingLow (negligible binding to plasma proteins).
MetabolismMetabolized exclusively within the gastrointestinal tract by intestinal bacteria and digestive enzymes; no hepatic metabolism.
Half-LifeApproximately 2 hours (for absorbed fraction).
ExcretionPrimarily excreted in feces as unchanged drug; less than 2% excreted in urine as metabolites.
BioavailabilityLow (1-2% as active drug).
Onset of ActionWithin 30 minutes of oral administration.
Peak Plasma Time1-2 hours (for absorbed fraction).
Duration of Action4-6 hours.

How It Works

Reversibly inhibits alpha-glucosidase enzymes in the brush border of the small intestine, delaying the digestion and absorption of complex carbohydrates and reducing postprandial hyperglycemia.

Mechanism Steps

1Acarbose binds reversibly to alpha-glucosidase enzymes in the brush border of the small intestine.
2Inhibition of these enzymes delays the hydrolysis of complex carbohydrates (starches, disaccharides) into absorbable monosaccharides.
3This reduces the rate of glucose absorption from the gut, thereby blunting postprandial blood glucose spikes.

๐Ÿ’ก How to Take acarsafe 50 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acarsafe 50 tablet

โœ… Common Side Effects

  • Flatulence
  • Diarrhea
  • Abdominal pain
  • Bloating
  • Nausea

๐Ÿšจ Serious Side Effects

  • Hepatitis
  • Jaundice
  • Pneumatosis cystoides intestinalis
  • Subileus
  • Hypoglycemia (when used with other antidiabetics)

โš ๏ธ Rare Side Effects

  • Skin rash
  • Urticaria
  • Edema
  • Elevated liver enzymes
  • Ileus

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Insulin Major Increased risk of hypoglycemia
Sulfonylureas Major Increased risk of hypoglycemia
Digoxin Moderate Reduced digoxin absorption
Warfarin Moderate Altered anticoagulant effect

๐Ÿšจ Major Interactions

  • Digoxin
  • Warfarin
  • Insulin
  • Sulfonylureas

โšก Moderate Interactions

  • Thiazide diuretics
  • Corticosteroids
  • Oral contraceptives
  • Calcium channel blockers

โ„น๏ธ Minor Interactions

  • Charcoal
  • Pancreatic enzymes
  • Neomycin

๐Ÿฝ๏ธ Food Interactions

Sucrose, Fructose, Lactose, Glucose

๐Ÿท Alcohol Interaction

May increase risk of hypoglycemia when combined with alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to acarbose; diabetic ketoacidosis; cirrhosis; inflammatory bowel disease; colonic ulceration; partial intestinal obstruction; chronic intestinal diseases with malabsorption; severe renal impairment (CrCl <25 mL/min).

๐Ÿ“Š Monitoring Parameters

Blood glucose (fasting and postprandial), HbA1c, liver function tests (periodically), renal function.

๐Ÿคฑ Lactation Safety

Unknown if excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

No specific antidote; treat symptomatically; do not administer oral carbohydrates (may cause severe flatulence and diarrhea); monitor blood glucose.

โฐ Missed Dose

Take the missed dose as soon as remembered, unless it is almost time for the next dose; do not double the dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acarsafe 50 tablet

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Alternative brands with exact same active ingredient (Acarbose (50mg)):

Medical Note: Always consult your doctor before switching medications.

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