abogest 500mg injection - Hydroxyprogesterone (500mg) medicine

Abogest 500mg Injection - Uses, Price, Side Effects

4.5 (17 reviews)

Hydroxyprogesterone (500mg)

🏭 Mits Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is abogest 500mg injection used for?

Abogest 500mg Injection contains Hydroxyprogesterone, a synthetic progestogen used to support pregnancy in cases of threatened abortion, recurrent pregnancy loss, and luteal phase deficiency. It works by maintaining the uterine lining and preventing contractions.

Generic Name: Hydroxyprogesterone
Manufacturer: Mits Healthcare Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 abogest 500mg injection Uses & Benefits

Luteal phase support in assisted reproductive technology, recurrent pregnancy loss, preterm labor prevention.

Off-label uses: Endometriosis, dysfunctional uterine bleeding.

📋 Drug Information

Generic Name(s)	Hydroxyprogesterone
Brand Name	Anin 500mg Injection
Manufacturer	Mits Healthcare Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GYNAECOLOGICAL
Action Class	Progestins (First generation)
Route of Administration	Intramuscular injection.
Storage	Store at 20-25°C (68-77°F); protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular administration results in slow absorption from the injection site.

DistributionDistributes widely in body tissues; crosses placenta.

Protein BindingApproximately 90% bound to plasma proteins.

MetabolismPrimarily hepatic via reduction and conjugation.

Half-LifeApproximately 8-10 days.

ExcretionPrimarily renal as metabolites.

Bioavailability100% (intramuscular).

Onset of ActionSlow; effects may take several days.

Peak Plasma Time2-3 days after intramuscular injection.

Duration of ActionUp to 2 weeks.

How It Works

Synthetic progestogen that mimics the effects of natural progesterone.

Mechanism Steps

1Binds to progesterone receptors in target tissues.

2Receptor-ligand complex translocates to nucleus.

3Modulates gene transcription of progesterone-responsive genes.

💡 How to Take abogest 500mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of abogest 500mg injection

✅ Common Side Effects

Injection site pain
Nausea
Headache
Dizziness
Breast tenderness

🚨 Serious Side Effects

Thromboembolism
Jaundice
Depression
Vision changes

⚠️ Rare Side Effects

Anaphylaxis
Cholestatic jaundice
Cerebral thrombosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Moderate	May alter anticoagulant effect
Carbamazepine	Moderate	Reduced efficacy of hydroxyprogesterone
Rifampin	Moderate	Decreased plasma concentration of hydroxyprogesterone

🚨 Major Interactions

CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

Warfarin
Corticosteroids

ℹ️ Minor Interactions

Antidiabetic agents
Antihypertensives

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Known hypersensitivity, thromboembolic disorders, severe hepatic disease, undiagnosed vaginal bleeding, pregnancy (except for specific indications).

📊 Monitoring Parameters

Liver function tests, signs of thromboembolism, pregnancy status.

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

Discontinue drug; symptomatic and supportive care.

⏰ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for abogest 500mg injection

View All

Alternative brands with exact same active ingredient (Hydroxyprogesterone (500mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026