Abingem 200mg Injection (gemcitabine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fever above 38°C or fever with chills
- Easy bruising or bleeding from the gums or nose
- Blood in urine or stool
- New or worsening breathlessness or chest tightness
- Severe tiredness or dizziness
- Decreased urine output or swelling of the legs
- Yellowing of the eyes or skin
- Severe headache with confusion, seizures, or vision changes
- Swelling of the face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is abingem 200mg injection used for?
This medicine is a chemotherapy injection containing gemcitabine, used to treat several cancers including lung, pancreatic, bladder, breast, and ovarian cancer. It is given into a vein by a healthcare professional and works by blocking DNA synthesis in cancer cells.
- Generic Name: Gemcitabine
- Manufacturer: Miracalus Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 abingem 200mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा जेमसिटाबिन नामक कीमोथेरेपी दवा है, जिसे नस के माध्यम से दिया जाता है। इसका उपयोग फेफड़ों के कैंसर, अग्नाशय के कैंसर, मूत्राशय के कैंसर, स्तन कैंसर, अंडाशय के कैंसर और पित्त नली के कैंसर के इलाज में किया जाता है। यह कैंसर कोशिकाओं के डीएनए को बनने से रोकती है, जिससे उनकी वृद्धि धीमी हो जाती है। यह दवा केवल अस्पताल या कैंसर डे-केयर सेंटर में प्रशिक्षित डॉक्टर या नर्स द्वारा ही दी जाती है। मरीज को इसे घर पर स्वयं नहीं लगाना चाहिए। इलाज के दौरान खून की जांच नियमित रूप से करानी जरूरी होती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, बुखार, थकान, भूख कम लगना, त्वचा पर दाने और फ्लू जैसे लक्षण शामिल हैं। कई मरीजों में खून की कोशिकाएं कम हो जाती हैं, जिससे संक्रमण, थकान और आसानी से चोट लगने या खून बहने की समस्या हो सकती है। गंभीर दुष्प्रभावों में तेज बुखार, गंभीर संक्रमण, सांस लेने में तकलीफ, गुर्दे या लीवर पर असर और एलर्जी प्रतिक्रिया शामिल हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल या कैंसर डे-केयर सेंटर में प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। घर पर स्वयं इंजेक्शन न लगाएं। अपने डॉक्टर को सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। संक्रमण से बचने के लिए भीड़-भाड़ वाली जगहों से बचें और हाथ धोते रहें। बुखार, ठंड लगना, आसानी से चोट लगना, खून बहना, सांस लेने में तकलीफ या सूजन होने पर तुरंत डॉक्टर को बताएं। इलाज के दौरान गर्भधारण से बचें और डॉक्टर की सलाह के अनुसार सुरक्षा उपाय अपनाएं। नियमित खून की जांच और फॉलो-अप जरूर कराएं।
💊 abingem 200mg injection Uses & Benefits
[{"condition":"Non-small cell lung cancer","description":"Used as first-line or later-line therapy, often in combination with platinum-based chemotherapy, for locally advanced or metastatic disease.","evidence":"Well-established"},{"condition":"Pancreatic cancer","description":"Used as adjuvant therapy after surgery and in advanced disease, commonly in combination with other agents.","evidence":"Well-established"},{"condition":"Bladder cancer","description":"Used in combination with cisplatin for advanced or metastatic urothelial carcinoma and in some neoadjuvant settings.","evidence":"Well-established"},{"condition":"Breast cancer","description":"Used as a single agent or in combination for metastatic breast cancer after prior anthracycline and taxane therapy.","evidence":"Well-established"},{"condition":"Ovarian cancer","description":"Used in platinum-resistant or recurrent ovarian cancer, often in combination with other chemotherapy drugs.","evidence":"Well-established"},{"condition":"Biliary tract cancer","description":"Used in combination with cisplatin for advanced or metastatic cholangiocarcinoma and gallbladder cancer.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Soft tissue sarcoma","description":"Sometimes used in combination regimens for advanced soft tissue sarcoma when standard options are limited.","evidence":"Limited"},{"condition":"Cervical cancer","description":"Occasionally used in recurrent or metastatic cervical cancer in selected patients.","evidence":"Limited"},{"condition":"Head and neck cancer","description":"Sometimes included in combination chemotherapy for recurrent or metastatic head and neck cancer.","evidence":"Limited"}]
Primary treatment for: Cancer
Also treats: Non-small cell lung cancer, Pancreatic cancer, Bladder cancer, Breast cancer, Ovarian cancer, Biliary tract cancer
📋 Drug Information
| Generic Name(s) | Gemcitabine |
| Brand Name | Abigem 200mg Injection |
| Manufacturer | Miracalus Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| Route of Administration | Intravenous |
| Storage | Store this medicine in its original carton in a refrigerator at 2°C to 8°C. Do not freeze. Protect from light. Once reconstituted or diluted, use according to the instructions provided by the hospital pharmacy, and discard any unused portion properly. |
| Shelf Life | The shelf life is usually 24 months from the date of manufacture when stored as directed. Always check the expiry date on the vial before use. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a nucleoside analogue that enters cancer cells and is converted into active diphosphate and triphosphate forms. The diphosphate form inhibits ribonucleotide reductase, reducing the building blocks needed for DNA synthesis. The triphosphate form competes with natural nucleotides and gets incorporated into DNA, causing chain termination and preventing cancer cells from copying their DNA. This dual action blocks cell division and triggers programmed cell death in rapidly dividing tumour cells.
Mechanism Steps
💡 How to Take abingem 200mg injection
Strength: This medicine is supplied as a 200 mg single-dose vial of sterile powder or concentrate for intravenous infusion.
Dosage Information
| Adult Dosage | The dose of this medicine is decided by a qualified oncologist and depends on the type of cancer, the treatment schedule, the patient's body surface area, blood counts, and liver and kidney function. Common schedules include weekly infusions or infusions on days 1 and 8 of a 21-day cycle, often in combination with other chemotherapy drugs. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never self-administer this medicine. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially bone marrow suppression, fatigue, and kidney effects. The dose is usually individualized by the oncologist based on general health, kidney function, and blood counts. |
| Renal Impairment | This medicine is cleared mainly by the kidneys. Patients with kidney impairment may need a lower dose or a different schedule, and kidney function should be monitored closely. The exact adjustment must be decided by the treating oncologist. |
| Hepatic Impairment | Patients with liver impairment may need careful monitoring and possible dose adjustment because this medicine can affect the liver. The exact adjustment must be decided by the treating oncologist. |
| Maximum Daily Dose | The maximum dose is not fixed and depends on the treatment protocol, body surface area, and the patient's tolerance. It must be determined by a qualified oncologist. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of abingem 200mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Live vaccines | Major | |
| Warfarin | Major | |
| Cisplatin | Moderate | |
| Aminoglycosides | Moderate | |
| Other chemotherapy agents | Moderate | |
| Hepatotoxic drugs | Moderate | |
| Paracetamol | Minor | |
| Ondansetron | Minor |
🚨 Major Interactions
- Live vaccines
- Warfarin and other anticoagulants
- Other bone marrow suppressive chemotherapy
⚡ Moderate Interactions
- Cisplatin
- Nephrotoxic drugs such as aminoglycosides
- Hepatotoxic drugs
🍷 Alcohol Interaction
Alcohol should be avoided during treatment with this medicine because it can increase the risk of liver injury, worsen nausea and dehydration, and add to fatigue. If you drink alcohol regularly, discuss this with your oncologist before starting treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergic reaction to gemcitabine or any component of this medicine","Active severe infection that is not controlled","Severe bone marrow suppression with very low blood counts","Pregnancy, unless the potential benefit clearly outweighs the risk","Breastfeeding during treatment","Severe liver or kidney impairment without specialist supervision"]
⚠️ Warnings & Precautions
["This medicine must be given only by a trained healthcare professional.","Blood counts must be checked regularly because of the risk of bone marrow suppression.","Report any fever, chills, or signs of infection immediately.","Use effective contraception during treatment and for a period advised by your doctor.","Avoid live vaccines during treatment.","Tell your doctor about all other medicines, supplements, and herbal products you take.","Use caution if you have liver or kidney problems, as dose adjustment may be needed.","Report new or worsening breathlessness, cough, or chest tightness promptly.","Avoid alcohol during treatment.","Keep all follow-up appointments for blood tests and scans."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because of the potential for serious harm to a nursing infant, breastfeeding should be stopped during treatment and for a period advised by the treating oncologist.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by healthcare professionals in a controlled setting. If an accidental overdose occurs, treatment is supportive and may include close monitoring of blood counts, liver and kidney function, and management of any symptoms. There is no specific antidote. Contact emergency medical services and inform them about this medicine.
⏰ Missed Dose
Because this medicine is given by a healthcare professional in a hospital or day-care setting, a missed dose usually means a missed appointment. Contact your oncology team as soon as possible to reschedule. Do not attempt to inject this medicine at home or double the next dose.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional in a hospital or cancer day-care unit. Do not attempt to inject it at home. Inform your doctor about all medicines, supplements, and herbal products you take, because some can increase the risk of bleeding, infection, or organ damage. Avoid close contact with people who have active infections, and wash your hands frequently. Use a soft toothbrush and an electric razor to reduce bleeding risk. Report any fever, chills, unusual bruising, blood in urine or stool, breathlessness, or swelling immediately. Do not receive any live vaccine without your oncologist's approval. Use effective contraception during treatment and for a period advised by your doctor, because this medicine can harm an unborn baby. Keep all follow-up appointments for blood tests and scans, as these are essential for safe treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the side effects of this medicine, especially bone marrow suppression, fatigue, and kidney effects. The dose is usually individualized based on general health, kidney function, and blood counts. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
This medicine can harm an unborn baby. Both men and women should use effective contraception during treatment and for a period advised by the oncologist. If you are planning a pregnancy, discuss it with your doctor before starting treatment. If pregnancy occurs during treatment, contact your doctor immediately.
🏥 Post-Surgery Considerations
This medicine may be used after surgery as adjuvant therapy for some cancers, such as pancreatic cancer. The timing of treatment after surgery depends on your recovery, wound healing, and the oncologist's plan. Follow your surgeon's and oncologist's advice about activity and wound care.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine before any dental procedure. Dental work may need to be delayed if your blood counts are low, because of the risk of bleeding and infection. Your oncologist may advise antibiotics before dental procedures in some cases.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Light activity such as walking is usually helpful, but avoid strenuous exercise, contact sports, or activities that could cause injury when your blood counts are low. Check with your oncologist before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Treatment with this medicine can cause fatigue, nausea, and low blood counts, which may affect your ability to work or drive. Many patients need to take time off during treatment cycles. Discuss your work schedule with your oncologist and employer, and avoid driving or operating machinery if you feel tired, dizzy, or unwell.
🛑 When to Stop This Medicine
Do not stop treatment on your own. Your oncologist will decide when to stop based on your response, side effects, and overall health. Contact your doctor immediately if you develop severe side effects such as high fever, bleeding, breathlessness, or signs of an allergic reaction.
📅 Long-Term Use Effects
Long-term effects depend on the total dose, duration of treatment, and other medicines used. Some patients may experience persistent fatigue, mild kidney or liver changes, and a small increase in the risk of secondary cancers. Regular follow-up with blood tests and scans is important to detect any late effects early. Most side effects improve after treatment ends, but recovery can take weeks to months.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the cancer type and stage, other chemotherapy drugs or combinations may be used instead of or along with this medicine.
Evidence: Well-establishedFor some cancers, targeted medicines that act on specific molecular changes may be an option.
Evidence: Well-established for selected cancersIn certain cancers, immunotherapy may be used alone or in combination with chemotherapy.
Evidence: Well-established for selected cancersRadiation may be used in some cases, either alone or with chemotherapy.
Evidence: Well-established for selected cancers💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during treatment with this medicine because of the risk of serious infection. Inactivated vaccines may be given, but the immune response may be weaker. Discuss all vaccinations with your oncologist before receiving them.
📦 Storage Guide
✅ DO
Store in the refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze the vial
✅ DO
Keep the vial in its original carton to protect from light
❌ DON'T
Do not store without the carton
✅ DO
Check the expiry date before use
❌ DON'T
Do not use an expired or damaged vial
✅ DO
Follow hospital pharmacy instructions for reconstituted solution
❌ DON'T
Do not store reconstituted solution for longer than advised
✈️ Traveling with This Medicine
This medicine is given in a hospital or cancer day-care setting, so travel should be planned around your treatment schedule. Carry a copy of your prescription and a letter from your oncologist explaining your diagnosis and treatment. If you need treatment while travelling, contact a cancer centre in advance and carry your medical records, recent blood test reports, and a list of medicines. Store the medicine as directed by the pharmacy and never carry it without proper documentation. Discuss travel plans with your oncologist before booking tickets.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine is given as an intravenous infusion by a trained healthcare professional in a hospital or cancer day-care setting. It is not self-administered at home.
A: The infusion usually takes about 30 minutes, but the exact time depends on the dose and the treatment protocol. Your healthcare team will tell you what to expect.
A: Measure your temperature and contact your oncology team immediately if it is 38°C or higher, or if you have chills. Fever during chemotherapy can be a sign of serious infection.
A: It is safer to have someone drive you home, especially if you feel tired, dizzy, or unwell after treatment.
A: Tell your oncologist about all medicines, supplements, and herbal products you take. Some can interact with this medicine and may need to be stopped or adjusted.
🤔 Common Patient Concerns
🔄 Substitutes for abingem 200mg injection
View AllAlternative brands with exact same active ingredient:
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gemchem 200mg injectionNeon Laboratories Ltd ₹439.20 67.2% CHEAPER
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gemce fil 200mg injectionFourrts India Laboratories Pvt Ltd ₹445.31 66.8% CHEAPER
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gembin 200mg injectionBiochem Pharmaceutical Industries ₹765.10 42.9% CHEAPER
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gembine 200mg injectionZydus Cadila ₹799.60 40.3% CHEAPER
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gemacta 200mg injectionMacleods Pharmaceuticals Pvt Ltd ₹865.37 35.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be injected at home like insulin.
Fact: This medicine must be given only by a trained healthcare professional in a hospital or cancer day-care setting. - Myth: This medicine is a painkiller for cancer pain.
Fact: This medicine is a chemotherapy drug that treats cancer itself; pain relief requires separate medicines. - Myth: If side effects are mild, the medicine is not working.
Fact: Side effects and treatment response are not directly linked; response is assessed by scans and blood tests. - Myth: Herbal supplements are always safe with chemotherapy.
Fact: Some supplements can interact with chemotherapy and should be discussed with the oncologist.
🔄 Alternative Options
Generic Alternatives
- Gemcitabine 200 mg injection
Brand Alternatives
- Abingem 200mg injection