abicet la 5mg/500mg/5mg tablet - Cetirizine (5mg) + Paracetamol (500mg) medicine

Abicet LA 5mg/500mg/5mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Alpic Biotech Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 1, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 01, 2026

What is abicet la 5mg/500mg/5mg tablet used for?

Abicet LA 5mg/500mg/5mg Tablet is a combination medicine containing Cetirizine (5mg) and Paracetamol (500mg). It is used to relieve symptoms of allergies such as runny nose, sneezing, and watery eyes, along with fever and mild pain. Cetirizine works by blocking histamine, while Paracetamol reduces fever and pain.

  • Generic Name: Cetirizine + Paracetamol
  • Manufacturer: Alpic Biotech Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š abicet la 5mg/500mg/5mg tablet Uses & Benefits

Allergic rhinitis, common cold symptoms, fever, mild to moderate pain.

Off-label uses: Urticaria, pruritus (cetirizine); migraine (paracetamol combination).

๐Ÿ“‹ Drug Information

Generic Name(s)Cetirizine + Paracetamol
Brand NameAlerid Cold Tablet
ManufacturerAlpic Biotech Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionCetirizine: Rapidly absorbed; Paracetamol: Rapidly and completely absorbed from GI tract.
DistributionCetirizine: Vd 0.5 L/kg; Paracetamol: Widely distributed, crosses placenta.
Protein BindingCetirizine: 93%; Paracetamol: 10-25%.
MetabolismCetirizine: Minimal hepatic metabolism; Paracetamol: Hepatic via conjugation (glucuronidation, sulfation) and CYP450 (minor).
Half-LifeCetirizine: 8.3 hours; Paracetamol: 2-3 hours.
ExcretionCetirizine: Renal (70% unchanged); Paracetamol: Renal (metabolites).
BioavailabilityCetirizine: ~70%; Paracetamol: 68-88%.
Onset of ActionCetirizine: 1 hour; Paracetamol: 30-60 minutes.
Peak Plasma TimeCetirizine: 1 hour; Paracetamol: 30-60 minutes.
Duration of ActionCetirizine: 24 hours; Paracetamol: 4-6 hours.

How It Works

Cetirizine: Selective H1 receptor antagonist; Paracetamol: COX inhibition in CNS, antipyretic via hypothalamic heat-regulating center.

Mechanism Steps

1Cetirizine binds to H1 receptors, blocking histamine action.
2Paracetamol inhibits COX-2 in CNS, reducing prostaglandin synthesis.
3Paracetamol acts on hypothalamic heat-regulating center to lower fever.

๐Ÿ’ก How to Take abicet la 5mg/500mg/5mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of abicet la 5mg/500mg/5mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Fatigue
  • Dry mouth
  • Nausea
  • Headache

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Blood dyscrasias

โš ๏ธ Rare Side Effects

  • Tachycardia
  • Urinary retention
  • Blurred vision
  • Confusion

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk due to paracetamol
Alcohol Moderate Increased risk of liver toxicity
MAOIs Moderate Increased anticholinergic effects

๐Ÿšจ Major Interactions

  • Alcohol
  • CNS depressants
  • MAOIs
  • Warfarin
  • Isoniazid

โšก Moderate Interactions

  • Barbiturates
  • Carbamazepine
  • Phenytoin
  • Rifampin
  • Zidovudine

โ„น๏ธ Minor Interactions

  • Chloramphenicol
  • Metoclopramide
  • Probenecid

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of paracetamol; grapefruit juice may increase cetirizine levels.

๐Ÿท Alcohol Interaction

Increased risk of hepatotoxicity with paracetamol; additive CNS depression with cetirizine.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe hepatic impairment, acute liver disease.

๐Ÿ“Š Monitoring Parameters

Liver function tests (if prolonged use or overdose), renal function, CBC.

๐Ÿคฑ Lactation Safety

Cetirizine: Excreted in milk, use caution; Paracetamol: Compatible.

๐Ÿ’Š Overdose Management

Paracetamol overdose: N-acetylcysteine; Cetirizine overdose: supportive care, activated charcoal.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jul 01, 2026

๐Ÿ”— View Profile

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