Abdocin DS 80mg/250mg Tablet - Uses, Price, Side Effects
What is abdocin ds 80mg/250mg tablet used for?
Abdocin DS 80mg/250mg Tablet is a combination of Drotaverine (an antispasmodic) and Mefenamic Acid (an NSAID). It is used to relieve abdominal pain and cramps associated with conditions like irritable bowel syndrome, menstrual cramps, and other smooth muscle spasms. Drotaverine relaxes muscle spasms, while Mefenamic Acid reduces pain and inflammation.
- Generic Name: Drotaverine + Mefenamic Acid
- Manufacturer: Altar Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ abdocin ds 80mg/250mg tablet Uses & Benefits
Smooth muscle spasms associated with GI, biliary, or urinary tract disorders; dysmenorrhea
Off-label uses: Renal colic, biliary colic, migraine (limited evidence)
๐ Drug Information
| Generic Name(s) | Drotaverine + Mefenamic Acid |
| Brand Name | Almefkem-D Tablet |
| Manufacturer | Altar Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Drotaverine inhibits phosphodiesterase IV, causing smooth muscle relaxation; Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take abdocin ds 80mg/250mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of abdocin ds 80mg/250mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Dizziness
- Headache
- Drowsiness
- Dry mouth
- Diarrhea
- Constipation
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Renal failure
- Hepatotoxicity
- Anaphylaxis
- Stevens-Johnson syndrome
- Bone marrow suppression
โ ๏ธ Rare Side Effects
- Pancreatitis
- Hepatic necrosis
- Agranulocytosis
- Thrombocytopenia
- Aplastic anemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Moderate | Increased risk of gastrointestinal bleeding |
| Lithium | Moderate | Increased lithium toxicity risk |
๐จ Major Interactions
- Warfarin
- Aspirin
- Lithium
- Methotrexate
- ACE inhibitors
- Diuretics
โก Moderate Interactions
- Anticoagulants
- Antiplatelets
- Corticosteroids
- SSRIs
- Alcohol
โน๏ธ Minor Interactions
- Antacids
- Digoxin
- Phenytoin
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active GI bleeding, severe hepatic/renal impairment, asthma, history of NSAID-induced reactions, third trimester pregnancy
๐ Monitoring Parameters
Renal function, hepatic function, CBC, blood pressure, signs of GI bleeding
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; gastric lavage, activated charcoal; monitor for CNS depression, seizures, renal failure
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.