aa ha syrup - Bromhexine (NA) + Dextromethorphan Hydrobromide (NA) medicine

AA HA Syrup - Uses, Price, Side Effects

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๐Ÿญ Leo Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is aa ha syrup used for?

AA HA Syrup combines Bromhexine, a mucolytic that thins mucus, and Dextromethorphan, a cough suppressant. It is used to relieve both wet and dry cough associated with respiratory conditions like colds, bronchitis, and sinusitis.

  • Generic Name: Bromhexine + Dextromethorphan Hydrobromide
  • Manufacturer: Leo Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š aa ha syrup Uses & Benefits

Productive and non-productive cough associated with respiratory tract infections

Off-label uses: None well-established

๐Ÿ“‹ Drug Information

Generic Name(s)Bromhexine + Dextromethorphan Hydrobromide
Brand NameAscodex Cough Syrup
ManufacturerLeo Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Antitussive
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionDistributed widely in body tissues
Protein BindingBromhexine: 99%; Dextromethorphan: 60-70%
MetabolismBromhexine: Hepatic; Dextromethorphan: Hepatic (CYP2D6)
Half-LifeBromhexine: 12 hours; Dextromethorphan: 3-6 hours
ExcretionBromhexine: Renal; Dextromethorphan: Renal
BioavailabilityBromhexine: 75-80%; Dextromethorphan: 11%
Onset of ActionBromhexine: 30 minutes; Dextromethorphan: 15-30 minutes
Peak Plasma TimeBromhexine: 1 hour; Dextromethorphan: 2.5 hours
Duration of ActionBromhexine: 6-8 hours; Dextromethorphan: 4-6 hours

How It Works

Bromhexine increases respiratory tract secretions and reduces mucus viscosity; Dextromethorphan suppresses cough by acting on cough center in medulla oblongata

Mechanism Steps

1Bromhexine stimulates bronchial glands to increase secretion of thin mucus
2Bromhexine breaks down mucopolysaccharides reducing mucus viscosity
3Dextromethorphan binds to NMDA receptors in cough center

๐Ÿ’ก How to Take aa ha syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of aa ha syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Drowsiness
  • Headache

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Serotonin syndrome
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Confusion
  • Hallucinations
  • Urinary retention

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAO Inhibitors Major Hypertensive crisis
CNS Depressants Moderate Increased sedation
Cough Suppressants Moderate Additive effects

๐Ÿšจ Major Interactions

  • MAOIs
  • SSRIs
  • Linezolid
  • Selegiline

โšก Moderate Interactions

  • CNS depressants
  • Alcohol
  • Quinidine
  • Amiodarone

โ„น๏ธ Minor Interactions

  • Grapefruit juice
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase dextromethorphan levels

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity, concurrent MAOI therapy, asthma, COPD, respiratory depression

๐Ÿ“Š Monitoring Parameters

Cough frequency, sputum characteristics, respiratory status

๐Ÿคฑ Lactation Safety

Use with caution; not recommended

๐Ÿ’Š Overdose Management

Activated charcoal, supportive care, naloxone for respiratory depression

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

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