acelife plus 500 mg/15 mg tablet - Paracetamol (500mg) + Serratiopeptidase (15mg) medicine

acelife plus 500 mg/15 mg tablet

4.5 (15 reviews)
๐Ÿญ Leo Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is acelife plus 500 mg/15 mg tablet used for?

Acelife Plus 500 mg/15 mg Tablet (Paracetamol + Serratiopeptidase) is used to treat PAIN ANALGESICS. It contains Paracetamol (500mg) + Serratiopeptidase (15mg), which Paracetamol: Inhibits COX-2 centrally; Serratiopeptidase: Hydrolyzes inflammator. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Paracetamol + Serratiopeptidase
  • Manufacturer: Leo Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š acelife plus 500 mg/15 mg tablet Uses & Benefits

Pain, inflammation, fever, sinusitis, post-surgical swelling

Off-label uses: Chronic pain, osteoarthritis

๐Ÿ“‹ Drug Information

Generic Name(s)Paracetamol + Serratiopeptidase
Brand NameAcelife Plus 500 mg/15 mg Tablet
ManufacturerLeo Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNon-opioid analgesic + Proteolytic enzyme
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionWidely distributed; crosses placenta
Protein BindingParacetamol: 10-25%; Serratiopeptidase: Not well characterized
MetabolismParacetamol: Hepatic (CYP2E1, CYP1A2, CYP3A4); Serratiopeptidase: Hepatic
Half-LifeParacetamol: 1.5-3 hours; Serratiopeptidase: ~6 hours
ExcretionParacetamol: Renal (mostly metabolites); Serratiopeptidase: Renal and fecal
BioavailabilityParacetamol: 60-90%; Serratiopeptidase: Not well defined
Onset of ActionParacetamol: 30-60 min; Serratiopeptidase: 1-2 hours
Peak Plasma TimeParacetamol: 30-60 min; Serratiopeptidase: 2-4 hours
Duration of ActionParacetamol: 4-6 hours; Serratiopeptidase: 8-12 hours

How It Works

Paracetamol: Inhibits COX-2 centrally; Serratiopeptidase: Hydrolyzes inflammatory mediators

Mechanism Steps

1Paracetamol inhibits COX-2 in the central nervous system, reducing prostaglandin synthesis.
2Serratiopeptidase hydrolyzes bradykinin, histamine, and other inflammatory mediators.
3Combined effect: analgesia and anti-inflammatory action.

๐Ÿ’ก How to Take acelife plus 500 mg/15 mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acelife plus 500 mg/15 mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Alcohol Major Increased hepatotoxicity
Isoniazid Major Increased hepatotoxicity
Carbamazepine Moderate Reduced paracetamol efficacy
Phenytoin Moderate Reduced paracetamol efficacy
Oral contraceptives Moderate Reduced serratiopeptidase efficacy
Chloramphenicol Minor Increased chloramphenicol toxicity
Probenecid Minor Reduced paracetamol excretion

๐Ÿšจ Major Interactions

  • Warfarin
  • Alcohol
  • Isoniazid

โšก Moderate Interactions

  • Carbamazepine
  • Phenytoin
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Chloramphenicol
  • Probenecid

๐Ÿฝ๏ธ Food Interactions

No significant interactions

๐Ÿท Alcohol Interaction

Increased hepatotoxicity risk with chronic alcohol use

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, severe hepatic impairment, active bleeding

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, bleeding time

๐Ÿคฑ Lactation Safety

Paracetamol: Safe; Serratiopeptidase: Insufficient data

๐Ÿ’Š Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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