Omnacortil 20 Tablet DT (Prednisolone 20mg): Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- High fever with chills
- Severe mood changes or confusion
If experiencing severe symptoms, call emergency services immediately.
What is a pred 20mg tablet used for?
This medicine contains Prednisolone 20mg, a corticosteroid used to treat severe allergies, asthma, arthritis, and other inflammatory conditions. It works by suppressing the immune system and reducing inflammation. It must be taken exactly as prescribed and never stopped suddenly.
- Generic Name: Prednisolone (20mg)
- Manufacturer: Acron Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 a pred 20mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा प्रेडनिसोलोन 20mg युक्त एक कॉर्टिकोस्टेरॉइड है, जिसका उपयोग गंभीर एलर्जी, अस्थमा, गठिया, सूजन आंत्र रोग, और कुछ ऑटोइम्यून बीमारियों के इलाज के लिए किया जाता है। यह शरीर में सूजन और प्रतिरक्षा प्रतिक्रियाओं को कम करके काम करती है। इस दवा को डॉक्टर के निर्देशानुसार ही लें और अचानक बंद न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में भूख बढ़ना, वजन बढ़ना, नींद न आना, मूड में बदलाव, और मुँहासे शामिल हैं। गंभीर दुष्प्रभावों में एड्रेनल ग्रंथि का दबना, संक्रमण का खतरा बढ़ना, हड्डियों का कमजोर होना, पेट के अल्सर, और उच्च रक्तचाप शामिल हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एड्रेनल संकट हो सकता है। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। संक्रमण वाले लोगों से दूर रहें। सर्जरी, डेंटल प्रोसीजर, या टीकाकरण से पहले अपने डॉक्टर को इस दवा के बारे में बताएं।
💊 a pred 20mg tablet Uses & Benefits
[{"condition":"Severe allergic reactions and anaphylaxis adjunct","description":"Used to reduce inflammation" class="semantic-link" title="Medicines for swelling">swelling and allergic inflammation after acute allergic episodes.","evidence":"Well-established"},{"condition":"Asthma exacerbations","description":"Helps control airway inflammation during moderate to severe asthma attacks.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis and other inflammatory arthritides","description":"Reduces joint pain, swelling, and stiffness by suppressing immune-mediated inflammation.","evidence":"Well-established"},{"condition":"Inflammatory bowel disease","description":"Induces remission in ulcerative colitis and Crohn's disease flares.","evidence":"Well-established"},{"condition":"Autoimmune and connective tissue diseases","description":"Used in lupus, vasculitis, and polymyalgia rheumatica to control systemic inflammation.","evidence":"Well-established"},{"condition":"Certain blood cancers and lymphomas","description":"Part of combination chemotherapy regimens for leukaemia and lymphoma.","evidence":"Well-established"},{"condition":"Severe dermatological conditions","description":"Treats pemphigus, severe eczema, and other steroid-responsive skin diseases.","evidence":"Well-established"},{"condition":"Organ transplantation","description":"Helps prevent rejection of transplanted organs as part of immunosuppressive therapy.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes used short-term to break a migraine cycle, though evidence is limited.","evidence":"Limited"},{"condition":"Bell's palsy","description":"May be used to reduce facial nerve inflammation, but evidence is mixed.","evidence":"Limited"},{"condition":"Chronic urticaria","description":"Occasionally used for severe antihistamine-resistant hives.","evidence":"Limited"}]
Primary treatment for: Inflammatory and autoimmune conditions
Also treats: Asthma, Rheumatoid arthritis, Inflammatory bowel disease, Severe allergies, Lupus, Certain blood cancers
📋 Drug Information
| Generic Name(s) | Prednisolone (20mg) |
| Brand Name | a pred 20mg tablet |
| Manufacturer | Acron Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL OTOLOGICALS |
| Action Class | Glucocorticoids |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise stated on the packaging. |
| WHO Guideline | Prednisolone is included in WHO essential medicines list for various inflammatory and autoimmune conditions. Specific recommendations vary by condition. |
| ICMR Guideline | ICMR guidelines recommend prednisolone for specific conditions such as severe asthma, rheumatoid arthritis, and inflammatory bowel disease, with dosing tailored to individual patient needs. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to glucocorticoid receptors inside cells. Once bound, the receptor-steroid complex moves into the nucleus and changes the transcription of many genes. It increases the production of anti-inflammatory proteins such as lipocortin-1 and decreases the production of pro-inflammatory cytokines, enzymes like cyclooxygenase-2, and adhesion molecules. This results in reduced swelling, less immune cell activity, and suppression of allergic and inflammatory responses throughout the body.
Mechanism Steps
💡 How to Take a pred 20mg tablet
Strength: Prednisolone 20mg immediate-release tablet
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, severity of the condition, age, weight, and renal and hepatic function. For acute inflammatory conditions, a typical starting dose might be 5 mg to 60 mg per day, taken as a single dose or divided doses. For severe conditions, higher doses may be used initially, followed by gradual tapering. Always follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects such as osteoporosis, hyperglycaemia, and hypertension. Doses should be individualized and monitored closely by a clinician. |
| Renal Impairment | No specific dose adjustment is typically required for renal impairment, but caution is advised in severe cases. Monitor fluid and electrolyte balance. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary based on clinical response and liver function tests. |
| Maximum Daily Dose | The maximum daily dose varies by indication and must be determined by a qualified clinician. Doses up to 60 mg per day are commonly used, but higher doses may be prescribed in specific severe conditions under close supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of a pred 20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Ibuprofen | Moderate | |
| Metformin | Moderate | |
| Furosemide | Moderate | |
| Live vaccines | Major | |
| Phenytoin | Moderate | |
| Aspirin | Moderate | |
| Insulin | Moderate |
🚨 Major Interactions
- Live vaccines
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
- Warfarin
- Antidiabetic drugs
⚡ Moderate Interactions
- NSAIDs
- Diuretics
- Anticholinesterases (e.g., donepezil)
🍷 Alcohol Interaction
Alcohol should be avoided or strictly limited while taking this medicine. Both alcohol and prednisolone can irritate the stomach lining, increasing the risk of gastritis and gastrointestinal bleeding. Alcohol may also worsen mood changes, sleep disturbances, and blood sugar fluctuations caused by this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to prednisolone or any component of the formulation","Untreated systemic fungal infections","Administration of live vaccines during high-dose therapy","Systemic viral infections in the absence of specific antiviral therapy"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly after prolonged use; taper gradually under medical supervision.","Use with caution in patients with diabetes, hypertension, osteoporosis, or peptic ulcer disease.","May mask signs of infection and increase susceptibility to infections.","Can cause mood changes, insomnia, and in rare cases, psychosis.","Long-term use may lead to cataracts, glaucoma, and bone loss.","Avoid contact with people who have chickenpox or measles if you are not immune.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Prednisolone is excreted in breast milk in small amounts. At doses up to 20 mg per day, it is generally considered compatible with breastfeeding. Higher doses may require timing feeds to reduce infant exposure. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose with prednisolone is unlikely to cause acute life-threatening effects. Long-term excessive dosing can lead to severe Cushing's syndrome and other complications. Treatment is supportive and may include tapering the dose gradually. Seek medical attention if a large amount is taken accidentally.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not stop this medicine suddenly, especially if you have been taking it for more than a few weeks, because this can cause a dangerous drop in your body's natural steroid production. Take this medicine with food or milk to reduce stomach irritation. Avoid contact with people who have infections such as chickenpox or measles, as this medicine weakens your immune response. Inform any healthcare professional treating you that you are taking this medicine, especially before surgery, dental work, or vaccination. Carry a steroid alert card or wear a medical alert bracelet if you are on long-term treatment. Monitor your blood sugar, blood pressure, and weight regularly if you have diabetes or hypertension. Do not receive live vaccines while taking this medicine unless your doctor specifically approves it.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of osteoporosis, hyperglycaemia, hypertension, and cognitive changes. Doses should be individualized and monitored closely. Fall prevention and bone health should be addressed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before starting or continuing this medicine. It is generally considered safe when medically necessary, but the dose should be minimized and monitored.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine. It may affect wound healing and increase infection risk. Stress-dose steroids may be needed during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, especially for long-term use. It may increase the risk of infection and affect healing after dental procedures. Stress-dose steroids may be considered.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid high-impact exercises that can stress bones, especially if you are on long-term therapy. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, mood changes, or insomnia, which can affect your ability to drive or operate machinery. Avoid driving if you feel drowsy or unfocused. Inform your employer if you are on long-term therapy.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Tapering is usually required after prolonged use.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to osteoporosis, cataracts, glaucoma, weight gain, diabetes, high blood pressure, and increased infection risk. Regular monitoring of bone density, blood sugar, blood pressure, and eye health is recommended. The dose should be tapered gradually when discontinuing.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and joint stiffness.
Evidence: Well-establishedAnti-inflammatory diet may help reduce reliance on steroids in some conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during and for at least 3 months after high-dose corticosteroid therapy. Inactivated vaccines are generally safe but may have reduced efficacy. Consult your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If crossing time zones, consult your doctor about adjusting the dosing schedule. Store at room temperature and avoid direct sunlight. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts reducing inflammation within 1 to 2 hours, but full benefits may take several hours to days depending on the condition.
A: No, never stop suddenly after prolonged use. It can cause adrenal insufficiency. Always taper under medical supervision.
A: It is generally considered safe when medically necessary. Consult your doctor for personalized advice.
🤔 Common Patient Concerns
🔄 Substitutes for a pred 20mg tablet
View AllAlternative brands with exact same active ingredient:
-
nisolone 20mg tabletPsychotropics India Ltd ₹3.90 82.7% CHEAPER
-
neopred forte 20mg tabletHema Laboratories ₹9.22 59% CHEAPER
-
emsolone 20mg tabletMedopharm ₹11.63 48.3% CHEAPER
-
monocortil 20mg tabletMarc Laboratories Pvt Ltd ₹12.42 44.8% CHEAPER
-
solon 20mg tabletApostle Remedies ₹12.46 44.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller; it reduces inflammation and suppresses the immune system. - Myth: You can stop this medicine anytime.
Fact: Stopping suddenly can cause serious adrenal insufficiency; always taper under medical supervision. - Myth: This medicine weakens your bones permanently.
Fact: Long-term use can reduce bone density, but this can be monitored and managed with calcium, vitamin D, and exercise.
🔄 Alternative Options
Generic Alternatives
- Prednisolone 20mg tablet
Brand Alternatives
- Omnacortil 20 Tablet DT