Nizonide 200mg Tablet Dt: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is zonaxid 200mg tablet dt used for?
This medicine is an antiprotozoal and anthelmintic agent used to treat intestinal infections caused by parasites such as Cryptosporidium and Giardia. It works by disrupting the energy metabolism of the parasites, leading to their death. It is available as a dispersible tablet and is usually taken for 3 days.
- Generic Name: Nitazoxanide (200mg)
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 zonaxid 200mg tablet dt के बारे में (Hindi Summary)
उपयोग: यह दवा नाइटाज़ोक्सानाइड 200 मिलीग्राम डिस्पर्सिबल टैबलेट के रूप में उपलब्ध है। यह मुख्य रूप से आंतों में होने वाले परजीवी संक्रमणों जैसे क्रिप्टोस्पोरिडियोसिस और जिआर्डियासिस के इलाज के लिए इस्तेमाल की जाती है। यह दवा परजीवियों के ऊर्जा चयापचय को बाधित करके उन्हें मार देती है। यह दवा डॉक्टर के पर्चे पर ही लेनी चाहिए और पूरा कोर्स पूरा करना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में पेट दर्द, जी मिचलाना, सिरदर्द और दस्त शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। दुर्लभ मामलों में एलर्जी, रक्त विकार या लीवर की समस्या हो सकती है। अगर आपको त्वचा पर चकत्ते, सूजन, या आंखों का पीला होना जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी दवाओं और एलर्जी के बारे में बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर की सलाह के बिना यह दवा न लें। यह दवा नींद या चक्कर ला सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। दवा को बच्चों की पहुंच से दूर रखें और निर्देशानुसार ही सेवन करें।
💊 zonaxid 200mg tablet dt Uses & Benefits
[{"condition":"Cryptosporidiosis","description":"This medicine is used to treat diarrhoea caused by Cryptosporidium parvum in immunocompetent patients.","evidence":"Well-established"},{"condition":"Giardiasis","description":"This medicine is effective against Giardia lamblia infection, which causes diarrhoea and malabsorption.","evidence":"Well-established"},{"condition":"Amoebiasis","description":"This medicine may be used in the treatment of intestinal amoebiasis caused by Entamoeba histolytica.","evidence":"Moderate"},{"condition":"Helminth infections","description":"This medicine has shown activity against certain intestinal worms, such as Ascaris lumbricoides and Trichuris trichiura.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Chronic hepatitis B","description":"Some studies have explored the use of this medicine in chronic hepatitis B, but it is not approved for this indication.","evidence":"Limited"},{"condition":"Chronic hepatitis C","description":"This medicine has been studied in combination with other agents for hepatitis C, but it is not a standard treatment.","evidence":"Limited"}]
Primary treatment for: Intestinal parasitic infections
Also treats: Cryptosporidiosis, Giardiasis, Amoebiasis
📋 Drug Information
| Generic Name(s) | Nitazoxanide (200mg) |
| Brand Name | zonaxid 200mg tablet dt |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antiprotozoal agents |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction, which is essential for the anaerobic energy metabolism of protozoa and helminths. This disruption leads to the inability of the parasite to produce energy, resulting in its death. This medicine is effective against a range of intestinal parasites without significantly affecting human cells.
Mechanism Steps
💡 How to Take zonaxid 200mg tablet dt
Strength: Dispersible tablet, 200 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for intestinal infections is 500 mg (two and a half 200 mg tablets) taken orally every 12 hours for 3 days. However, the dose and duration may vary depending on the specific infection being treated and the patient's condition. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Clinical studies of this medicine did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. |
| Renal Impairment | No dosage adjustment is recommended for patients with mild to moderate renal impairment. This medicine should be used with caution in patients with severe renal impairment. |
| Hepatic Impairment | No dosage adjustment is recommended for patients with mild to moderate hepatic impairment. This medicine is contraindicated in patients with severe hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 1000 mg (five 200 mg tablets) for adults. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of zonaxid 200mg tablet dt
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
⚡ Moderate Interactions
- Methotrexate
🍷 Alcohol Interaction
Alcohol may worsen the side effects of this medicine, such as dizziness and stomach upset. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Nitazoxanide or any component of the formulation","Severe hepatic impairment","Severe renal impairment"]
⚠️ Warnings & Precautions
["This medicine should be used with caution in patients with liver disease.","This medicine should be used with caution in patients with kidney disease.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","This medicine should not be used for longer than prescribed without medical advice.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor before breastfeeding.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Gastric lavage may be considered if the overdose is recent and the patient is seen within a short time.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, tell your doctor if you are allergic to Nitazoxanide or any other medicines. Inform your doctor about all the medicines you are taking, including prescription, over-the-counter, and herbal products, as this medicine may interact with them. Do not take this medicine without a prescription. It is important to take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking this medicine. This medicine may make you feel dizzy or sleepy; avoid driving or operating heavy machinery until you know how it affects you. Keep this medicine out of the reach of children. Store it in a cool, dry place away from direct sunlight. Do not use it after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine. Dose selection should be cautious, and liver and kidney function should be monitored.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anaesthesiologist that you are taking this medicine. It may interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are usually needed, but it is important for your dentist to know your medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue. Avoid strenuous exercise until you know how it affects you. Light activity is generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the prescribed course or as directed by your doctor. Do not stop early, as it may lead to treatment failure or resistance. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
This medicine is usually prescribed for a short duration (3 days). Long-term use is not recommended without medical supervision. If you need to take it for a longer period, your doctor will monitor your liver and kidney function regularly.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps prevent dehydration caused by diarrhoea.
Evidence: Well-establishedMay help restore gut flora during and after infection.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your doctor that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If you are crossing time zones, adjust your dosing schedule accordingly, but do not take a double dose. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 1-2 days, but you must complete the full course as prescribed.
A: Yes, taking this medicine with food can reduce stomach upset and improve absorption.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for zonaxid 200mg tablet dt
View AllAlternative brands with exact same active ingredient:
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zimdax 200mg tablet dtUSV Ltd ₹29.70 4.8% COSTLIER
-
nitarid 200mg tablet dtCipla Ltd ₹30.31 7% COSTLIER
-
Nitazet 200mg Tablet DTGlenmark Pharmaceuticals Ltd ₹32.50 14.7% COSTLIER
-
zstop 200mg tabletManeesh Pharmaceuticals Ltd ₹32.78 15.7% COSTLIER
-
Nitcol 200mg TabletSun Pharmaceutical Industries Ltd ₹33.16 17% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of diarrhoea.
Fact: This medicine is only effective against specific parasitic infections. It is not effective for diarrhoea caused by viruses or bacteria. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: It is important to complete the full course as prescribed to ensure the infection is fully cleared and to prevent resistance.
🔄 Alternative Options
Generic Alternatives
- Nitazoxanide 200 mg dispersible tablet
Brand Alternatives
- Nizonide 200mg Tablet DT