Dubagest 300 Soft Gelatin Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden shortness of breath or chest pain
- Swelling, pain, or redness in one leg
- Severe allergic reaction with swelling of face, lips, or throat
- Yellowing of skin or eyes
- Severe abdominal pain
- Unusual vaginal bleeding
If experiencing severe symptoms, call emergency services immediately.
What is zistron 300mg soft gelatin capsule used for?
This medicine is a progesterone supplement used to treat conditions related to low progesterone levels, such as threatened miscarriage, infertility, and hormone replacement therapy. It works by binding to progesterone receptors and supporting the uterine lining.
- Generic Name: Progesterone (300mg)
- Manufacturer: Vanshita Lifecare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 zistron 300mg soft gelatin capsule के बारे में (Hindi Summary)
उपयोग: यह दवा प्रोजेस्टेरोन हार्मोन की कमी से होने वाली समस्याओं के इलाज में इस्तेमाल की जाती है। इसका उपयोग गर्भपात के खतरे को कम करने, बांझपन के इलाज में सहायता के लिए, और मासिक धर्म को नियमित करने में किया जाता है। यह दवा गर्भाशय की परत को मजबूत बनाकर गर्भधारण को सहारा देती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, सिरदर्द, स्तनों में कोमलता, मतली और मासिक धर्म में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन अगर सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पैर में दर्द और सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। दवा लेने के बाद नींद या चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। दवा को बंद करने से पहले डॉक्टर से सलाह लें।
💊 zistron 300mg soft gelatin capsule Uses & Benefits
[{"condition":"Threatened miscarriage","description":"This medicine is used to support early pregnancy when there is a threat of miscarriage due to low progesterone levels.","evidence":"Well-established"},{"condition":"Recurrent miscarriage","description":"Prescribed to women with a history of recurrent miscarriages to help maintain pregnancy.","evidence":"Moderate"},{"condition":"Luteal phase support in infertility treatment","description":"Used during assisted reproductive techniques such as IVF to support the uterine lining.","evidence":"Well-established"},{"condition":"Hormone replacement therapy","description":"Used in combination with estrogen to protect the uterus in postmenopausal women.","evidence":"Well-established"},{"condition":"Secondary amenorrhea","description":"Used to induce menstruation in women who have missed periods due to low progesterone.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Preterm birth prevention","description":"Sometimes prescribed off-label to prevent preterm birth in high-risk pregnancies.","evidence":"Limited"},{"condition":"Luteal phase defect","description":"May be used off-label to treat luteal phase defect in some fertility clinics.","evidence":"Limited"}]
Primary treatment for: Progesterone deficiency
Also treats: Threatened miscarriage, Recurrent miscarriage, Infertility, Secondary amenorrhea, Hormone replacement therapy
📋 Drug Information
| Generic Name(s) | Progesterone (300mg) |
| Brand Name | zistron 300mg soft gelatin capsule |
| Manufacturer | Vanshita Lifecare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Natural Progesterone |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to progesterone receptors in the nucleus of target cells. Once bound, it activates specific genes that produce proteins responsible for the normal functioning of the reproductive system. In the uterus, it transforms the endometrium into a secretory state, making it suitable for implantation of a fertilized egg. It also reduces uterine contractions, helping to maintain pregnancy. Additionally, it influences the cervical mucus and the fallopian tubes to support sperm transport and fertilization. In the breast, it prepares the mammary glands for milk production. This medicine also has mild sedative effects due to its action on the central nervous system.
Mechanism Steps
💡 How to Take zistron 300mg soft gelatin capsule
Strength: Soft gelatin capsule containing 300 mg of progesterone.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the indication, age, weight, and medical condition. For threatened miscarriage, a common dose is 300 mg once daily or as directed. For luteal support, the dose may be 200-300 mg daily. Always follow your doctor's prescription exactly. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and follow your doctor's advice. |
| Renal Impairment | No specific dose adjustment is recommended for patients with kidney disease. However, use with caution and consult your doctor. |
| Hepatic Impairment | This medicine is metabolized in the liver. Dose adjustment may be needed in patients with liver disease. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is determined by your doctor based on your condition. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of zistron 300mg soft gelatin capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Rifampicin | Major | |
| Ketoconazole | Moderate | |
| Carbamazepine | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Warfarin
- Rifampicin
⚡ Moderate Interactions
- Ketoconazole
- Carbamazepine
🍷 Alcohol Interaction
Alcohol may increase the drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to progesterone or any ingredient in the capsule","Undiagnosed vaginal bleeding","Known or suspected breast cancer","History of blood clots","Severe liver disease"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.","Do not use this medicine if you are allergic to progesterone or any of its ingredients.","Inform your doctor if you have a history of blood clots, liver disease, or breast cancer.","This medicine should be used with caution in patients with epilepsy, migraine, or asthma.","Do not stop taking this medicine without consulting your doctor.","Keep out of reach of children."]
🤱 Lactation Safety
This medicine may pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include severe drowsiness, dizziness, or nausea. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Before starting this medicine, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Although this medicine is often used to support pregnancy, it should only be taken under strict medical supervision. Inform your doctor about all your medical conditions, especially liver disease, kidney disease, epilepsy, migraine, asthma, or a history of blood clots. Do not drive or operate heavy machinery if you feel drowsy or dizzy after taking this medicine. Avoid alcohol while taking this medicine, as it can increase drowsiness and dizziness. Take this medicine exactly as prescribed. Do not change the dose or stop taking it without consulting your doctor. If you miss a dose, follow your doctor's instructions or the missed dose guidance provided. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children. Do not use this medicine after the expiry date. If you experience any severe or unusual symptoms, contact your doctor immediately. Regular follow-up appointments are important to monitor your response and adjust the dose if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and follow your doctor's advice.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It may be prescribed to support early pregnancy in some cases.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may affect blood clotting and interact with anesthetic agents.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may affect bleeding and interact with local anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience drowsiness or dizziness after taking this medicine, avoid strenuous exercise or activities that require alertness. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Inform your employer if your work involves such tasks.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will advise you on when and how to stop based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with an increased risk of blood clots, liver problems, and breast cancer. Regular monitoring with your doctor is essential. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An alternative progestin used for similar indications.
Evidence: Well-establishedAnother route of administration for progesterone.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, consult your doctor about adjusting the timing of your doses. Keep it in your carry-on luggage to avoid loss or temperature extremes. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of action varies depending on the indication. For luteal support, effects may take several days. For sedation, effects can occur within 30-60 minutes.
A: Yes, taking this medicine with food is recommended to improve absorption and reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for zistron 300mg soft gelatin capsule
View AllAlternative brands with exact same active ingredient:
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gestorma 300mg tablet srAroma Healthcare ₹11.72 97.2% CHEAPER
-
backup 300 sr capsuleSyndicate Life Sciences Pvt Ltd ₹73.13 82.3% CHEAPER
-
pgton 300mg tablet srUnison Pharmaceuticals Pvt Ltd ₹239.06 42.2% CHEAPER
-
proford 300mg tabletMaxford Labs Pvt. Ltd. ₹324.84 21.4% CHEAPER
-
stargest 300mg tablet srLividus Pharmaceuticals Pvt Ltd ₹328.13 20.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a contraceptive.
Fact: This medicine is not a contraceptive. It is used to support pregnancy and treat progesterone deficiency. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Progesterone soft gelatin capsules
Brand Alternatives
- Dubagest 300
- Gestofit 300
- Susten 300
- Naturogest 300