Atorvafine TG 10mg/160mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe muscle pain, tenderness, or weakness, especially with dark urine.
- Yellowing of skin or eyes, dark urine, or right upper abdominal pain.
- Severe abdominal pain that may radiate to the back, with nausea and vomiting.
- Swelling of face, lips, tongue, or throat, or difficulty breathing.
- Chest pain, shortness of breath, or irregular heartbeat.
- Sudden severe headache with visual changes.
- Decreased urine output or swelling in legs and feet.
- Unusual bleeding or bruising.
If experiencing severe symptoms, call emergency services immediately.
What is xtor-f tablet used for?
This medicine is a prescription combination of atorvastatin 10 mg and fenofibrate 160 mg used to treat mixed dyslipidemia. It lowers bad cholesterol and triglycerides while raising good cholesterol. It is taken once daily orally with regular blood tests to monitor liver, kidney, and muscle safety.
- Generic Name: Atorvastatin (10mg) + Fenofibrate (160mg)
- Manufacturer: Ipca Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 xtor-f tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरवास्टेटिन 10 मिलीग्राम और फेनोफाइब्रेट 160 मिलीग्राम का संयोजन है। इसका उपयोग मिश्रित डिस्लिपिडेमिया के इलाज के लिए किया जाता है, जिसमें खराब कोलेस्ट्रॉल (LDL) और ट्राइग्लिसराइड दोनों बढ़े हुए होते हैं। यह दवा खराब कोलेस्ट्रॉल को कम करने, ट्राइग्लिसराइड को घटाने और अच्छे कोलेस्ट्रॉल (HDL) को बढ़ाने में मदद करती है। यह दिल के दौरे और स्ट्रोक के खतरे को कम करने में सहायक है। यह केवल डॉक्टर के पर्चे पर मिलती है और इसे नियमित रूप से लेना जरूरी है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, जी मिचलाना, पेट में गड़बड़ी, दस्त, कब्ज, मांसपेशियों में दर्द और लिवर एंजाइम में हल्की वृद्धि शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इन्हें नजरअंदाज न करें। तेज मांसपेशियों में दर्द, कमजोरी, गहरे रंग का पेशाब, आंखों या त्वचा का पीला पड़ना, पेट में तेज दर्द, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पानी के साथ पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। शराब का सेवन न करें या बहुत कम करें। लिवर, किडनी और कोलेस्ट्रॉल की नियमित जांच कराते रहें। गर्भवती होने या गर्भधारण की योजना बनाने पर तुरंत डॉक्टर को बताएं। दवा को कमरे के तापमान पर, धूप और नमी से दूर रखें।
💊 xtor-f tablet Uses & Benefits
[{"condition":"Mixed dyslipidemia","description":"Used to lower elevated LDL cholesterol and triglycerides while raising HDL cholesterol in patients with both high cholesterol and high triglycerides.","evidence":"Well-established"},{"condition":"Hypertriglyceridemia with high LDL","description":"Helps reduce very high triglyceride levels and LDL cholesterol when a single agent is not enough.","evidence":"Well-established"},{"condition":"Primary hypercholesterolemia","description":"Used as add-on therapy when statin alone does not achieve target LDL levels and triglycerides are also elevated.","evidence":"Well-established"},{"condition":"Diabetic dyslipidemia","description":"Commonly prescribed in patients with type 2 diabetes who have high triglycerides and low HDL cholesterol.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Non-alcoholic fatty liver disease","description":"Sometimes used to improve lipid profile in patients with fatty liver, but not a primary treatment.","evidence":"Limited"},{"condition":"HIV-associated dyslipidemia","description":"May be used to manage lipid abnormalities caused by antiretroviral therapy, under specialist care.","evidence":"Limited"}]
Primary treatment for: Mixed dyslipidemia
Also treats: Hypertriglyceridemia, Hypercholesterolemia, Diabetic dyslipidemia, Metabolic syndrome
📋 Drug Information
| Generic Name(s) | Atorvastatin (10mg) + Fenofibrate (160mg) |
| Brand Name | xtor-f tablet |
| Manufacturer | Ipca Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. Do not refrigerate unless specified by the manufacturer. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Atorvastatin selectively inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis in the liver. This reduces hepatic cholesterol production, which leads to increased clearance of LDL cholesterol from the blood. Fenofibrate activates peroxisome proliferator-activated receptor alpha, which increases fatty acid oxidation and lipoprotein lipase activity. This lowers triglycerides and raises HDL cholesterol. Together, they provide broader lipid control than either agent alone.
Mechanism Steps
💡 How to Take xtor-f tablet
Strength: Tablet containing atorvastatin 10 mg and fenofibrate 160 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily. The dose may be adjusted by your doctor based on your lipid levels, kidney function, liver function, and response to treatment. Take it at the same time each day, with or without food. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially muscle and kidney effects. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no dose adjustment is usually needed, but monitoring is advised. In severe kidney impairment (eGFR less than 30 mL/min/1.73 m2), this medicine is contraindicated. Consult your doctor for alternative therapy. |
| Hepatic Impairment | This medicine is contraindicated in active liver disease or unexplained persistent liver enzyme elevation. In patients with mild to moderate liver impairment, use with caution and monitor liver function closely. Dose adjustment may be needed. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet containing atorvastatin 10 mg and fenofibrate 160 mg. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of xtor-f tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Clarithromycin | Major | |
| Itraconazole | Major | |
| Colchicine | Moderate | |
| Digoxin | Moderate | |
| Oral contraceptives | Moderate | |
| Thiazide diuretics | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- Cyclosporine
- Gemfibrozil
- Strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, ritonavir)
⚡ Moderate Interactions
- Colchicine
- Digoxin
- Oral contraceptives
- Thiazide diuretics
🍷 Alcohol Interaction
Alcohol should be limited or avoided while taking this medicine. Alcohol can increase the risk of liver damage from atorvastatin and can raise triglyceride levels, which counteracts the effect of fenofibrate. If you drink alcohol, discuss safe limits with your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active liver disease or unexplained persistent elevation of liver enzymes","Known hypersensitivity to atorvastatin, fenofibrate, or any component of the formulation","Gallbladder disease","Severe kidney impairment (eGFR less than 30 mL/min/1.73 m2)","Pregnancy and breastfeeding","Use in women of childbearing potential not using effective contraception"]
⚠️ Warnings & Precautions
["This medicine can cause muscle pain, tenderness, or weakness. Report severe or persistent muscle symptoms immediately.","Liver function should be monitored before and during treatment. Report symptoms of liver injury.","Fenofibrate may increase the risk of gallstones and pancreatitis. Report severe abdominal pain.","This medicine may increase blood sugar levels. Diabetic patients should monitor glucose closely.","Avoid excessive alcohol consumption due to increased liver risk.","Tell your doctor about all other medicines, especially blood thinners, diabetes medicines, and other cholesterol medicines.","Do not use this medicine during pregnancy or breastfeeding.","This medicine is not for children. Safety and effectiveness in pediatric patients are not established.","Use with caution in elderly patients and those with kidney or liver impairment.","Do not stop this medicine without consulting your doctor."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding. It is not known whether atorvastatin and fenofibrate pass into breast milk in significant amounts, but potential risks to the infant cannot be excluded. Consult your doctor for alternative treatments if you are breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause severe muscle pain, liver toxicity, or pancreatitis. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Hemodialysis is not effective for removing atorvastatin or fenofibrate. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water. It can be taken with or without food, but taking it with meals may reduce stomach upset. Do not crush, chew, or break the tablet unless your doctor approves. Do not double the dose if you miss one. Keep all follow-up appointments for blood tests, including liver function, kidney function, and lipid profile. Tell your doctor about all other medicines, supplements, and herbal products you take, especially blood thinners, diabetes medicines, and other cholesterol medicines. Avoid excessive alcohol because it can increase liver risk. Do not start or stop this medicine without medical advice. If you become pregnant or plan to become pregnant, contact your doctor immediately. Store this medicine at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially muscle and kidney effects. Start with a lower dose and monitor closely. Regular assessment of kidney and liver function is important. Fall risk may increase if dizziness or muscle weakness occurs.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. Use effective contraception while taking this medicine. If you plan to become pregnant, consult your doctor to switch to a safer alternative before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily before surgery due to bleeding risk and interactions with anesthetic agents. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may increase bleeding risk, especially if you are also taking blood thinners. Your dentist may recommend stopping it temporarily or taking precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but if you experience muscle pain, tenderness, or weakness, stop exercising and consult your doctor. Avoid strenuous exercise if you have muscle symptoms. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or muscle weakness in some people. Do not drive or operate heavy machinery until you know how it affects you. Most people can continue their daily activities normally. If you experience side effects that interfere with work, consult your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as severe muscle pain, liver symptoms, or allergic reactions, stop the medicine and seek immediate medical attention. Your doctor may adjust the dose or switch to an alternative treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. It effectively lowers cardiovascular risk. Regular monitoring of liver enzymes, kidney function, and lipid profile is required. Rarely, long-term use may be associated with muscle toxicity, liver injury, or gallstones. Do not stop the medicine without medical advice. Lifestyle changes should continue alongside treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A heart-healthy diet and regular physical activity can improve lipid levels and complement medicine.
Evidence: Well-establishedMay help lower triglycerides, but should be used under medical supervision.
Evidence: ModerateCan raise HDL and lower triglycerides, but has significant side effects and interactions.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established from available information. Continue routine vaccinations as recommended by your doctor. Inform your healthcare provider about this medicine before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If traveling across time zones, take your dose at the usual time or adjust gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Lipid-lowering effects begin within 1 to 2 weeks, but maximum effect on LDL cholesterol is usually seen after 2 to 4 weeks of continuous therapy.
A: Yes, you can take it with or without food. Taking it with meals may reduce stomach upset and improve fenofibrate absorption.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop without consulting your doctor. High cholesterol often has no symptoms, and stopping the medicine can cause levels to rise again.
A: No, this medicine is not recommended during pregnancy. It may harm the developing baby. Use effective contraception and consult your doctor if you plan to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for xtor-f tablet
View AllAlternative brands with exact same active ingredient:
-
atorastin f 10mg/160mg tabletZeelab Pharmacy Pvt Ltd ₹23.44 91% CHEAPER
-
drlipid fb tabletDR Best pharmaceuticals Pvt Ltd ₹27.19 89.6% CHEAPER
-
davastat f 10mg/160mg tabletDavaindia Generic Pharmacy ₹30.00 88.5% CHEAPER
-
ozovas-f tabletOzone Pharmaceuticals Ltd ₹33.22 87.3% CHEAPER
-
kapstor f 10mg/160mg tabletRawlley Healthcare Pvt Ltd ₹42.19 83.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once cholesterol levels are normal.
Fact: Cholesterol levels return to high if the medicine is stopped. It is usually a long-term treatment. Do not stop without consulting your doctor. - Myth: This medicine causes immediate weight loss.
Fact: This medicine does not cause weight loss. It lowers cholesterol and triglycerides. Weight loss requires diet and exercise. - Myth: Taking this medicine means I can eat whatever I want.
Fact: Diet and exercise are still essential. This medicine works best when combined with a heart-healthy lifestyle. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with active liver disease, severe kidney disease, gallbladder disease, or during pregnancy. Always consult your doctor.
🔄 Alternative Options
Generic Alternatives
- Atorvastatin + Fenofibrate generic
Brand Alternatives
- Atorvafine TG 10mg/160mg Tablet