xofen 16mg tablet sr - Lornoxicam (16mg) medicine

Aslor 16mg Tablet Sr: Complete Medicine Guide

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🏭 Torrent Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. NSAIDs should be avoided during the third trimester of pregnancy due to risk of premature closure of the ductus arteriosus. Consult your doctor for individualized advice. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is xofen 16mg tablet sr used for?

This medicine contains Lornoxicam 16mg, an NSAID used to relieve pain and inflammation in conditions like arthritis and acute injuries. It works by blocking COX enzymes. Take it with food, avoid alcohol, and follow your doctor's instructions.

  • Generic Name: Lornoxicam (16mg)
  • Manufacturer: Torrent Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 xofen 16mg tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा लोर्नोक्सिकैम 16mg युक्त एक नॉन-स्टेरॉयडल एंटी-इंफ्लेमेटरी ड्रग (NSAID) है। इसका उपयोग गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), मांसपेशियों की चोट, दांत दर्द, और सर्जरी के बाद होने वाले दर्द और सूजन को कम करने के लिए किया जाता है। यह दर्द और सूजन पैदा करने वाले प्रोस्टाग्लैंडिन नामक रसायनों को कम करके काम करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अपच, जी मिचलाना, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, यकृत की समस्या, और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको काला मल, उल्टी में खून, या गंभीर पेट दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ या दूध के साथ लें ताकि पेट में जलन न हो। गोली को चबाएं या तोड़ें नहीं, पूरा निगल लें। इस दवा के साथ शराब न पिएं। बिना डॉक्टर की सलाह के कोई अन्य दर्द निवारक दवा न लें। यदि आपको पेट अल्सर, गुर्दे या यकृत की बीमारी, उच्च रक्तचाप, या हृदय रोग है, तो अपने डॉक्टर को बताएं। कम से कम प्रभावी खुराक का उपयोग करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 xofen 16mg tablet sr Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain, stiffness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling in joints affected by osteoarthritis, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, swelling, and inflammation associated with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Provides short-term relief for acute pain from strains, sprains, and other musculoskeletal injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for the management of moderate to severe pain following surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain","description":"Effective in relieving pain and inflammation after dental procedures such as tooth extraction.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks due to its anti-inflammatory effects.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be prescribed off-label for menstrual pain and cramps.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and acute musculoskeletal injuries.

Also treats: Post-operative pain, Dental pain, Acute gout, Ankylosing spondylitis

📋 Drug Information

Generic Name(s)Lornoxicam (16mg)
Brand Namexofen 16mg tablet sr
ManufacturerTorrent Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Swallow the sustained-release tablet whole; do not crush or chew it.
3
Avoid alcohol while taking this medicine to prevent gastrointestinal bleeding.
4
Do not take other NSAIDs or pain relievers without consulting your doctor.
5
Use the lowest effective dose for the shortest duration possible.
6
Report any signs of bleeding, such as black stools or easy bruising, immediately.
7
Keep follow-up appointments for monitoring kidney and liver function.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Acute muscle injury
This medicine can relieve pain and inflammation.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLornoxicam is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability is high, approximately 90-100%. Food may slightly delay the time to peak concentration but does not significantly affect the extent of absorption.
DistributionLornoxicam is highly bound to plasma proteins and has a small volume of distribution (approximately 0.1-0.2 L/kg), indicating limited distribution into extravascular tissues. It crosses the placental barrier and is excreted in breast milk in small amounts.
Protein BindingLornoxicam is approximately 99% bound to plasma proteins, primarily albumin.
MetabolismLornoxicam is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, particularly CYP2C9. The main metabolite is 5'-hydroxy-lornoxicam, which is pharmacologically inactive.
Half-LifeThe elimination half-life of lornoxicam is approximately 3 to 4 hours.
ExcretionLornoxicam and its metabolites are excreted primarily via the kidneys (about 60%) and in feces (about 40%).
BioavailabilityThe oral bioavailability of lornoxicam is approximately 90-100%.
Onset of ActionThe onset of analgesic effect is typically within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 1 to 2 hours after oral administration.
Duration of ActionThe duration of analgesic effect is approximately 6 to 8 hours, but the sustained-release formulation may provide prolonged action.

How It Works

This medicine works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for converting arachidonic acid into prostaglandins and thromboxanes. Prostaglandins are key mediators of pain, inflammation, and fever. Lornoxicam inhibits both COX-1 and COX-2 enzymes, though it may have a slightly higher selectivity for COX-2. By blocking these enzymes, it reduces the production of prostaglandins, thereby decreasing pain, swelling, and inflammation. This mechanism is similar to other NSAIDs but lornoxicam is known for its potent analgesic and anti-inflammatory effects.

Mechanism Steps

1
Absorption and distribution: After oral administration, lornoxicam is absorbed from the gastrointestinal tract and distributed throughout the body, reaching inflamed tissues.
2
COX enzyme inhibition: Lornoxicam binds to and inhibits the COX-1 and COX-2 enzymes, preventing the conversion of arachidonic acid to prostaglandin H2.
3
Reduced prostaglandin synthesis: Inhibition of COX enzymes leads to decreased production of prostaglandins, prostacyclin, and thromboxanes.
4
Decreased pain and inflammation: Lower levels of prostaglandins result in reduced pain perception, decreased swelling, and less fever.
5
Reversible effect: The inhibition is reversible, and enzyme activity returns to normal after the medicine is cleared from the body.

💡 How to Take xofen 16mg tablet sr

Strength: Sustained-release tablet, 16 mg

1Take this medicine orally with a full glass of water.
2Swallow the sustained-release tablet whole. Do not crush, chew, or break it.
3Take with food or milk to reduce stomach upset.
4Take at the same time each day to maintain consistent levels.
5Do not take more than the prescribed dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 8 mg to 16 mg per day, taken orally, depending on the severity of pain and inflammation. For acute pain, an initial dose of 16 mg may be given, followed by 8 mg twice daily. The maximum recommended daily dose is 16 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Take with food to reduce gastrointestinal irritation.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use the lowest effective dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with mild to moderate renal impairment, no dose adjustment is usually necessary, but caution is advised. In severe renal impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, no dose adjustment is usually necessary, but caution is advised. In severe hepatic impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician based on hepatic function.
Maximum Daily Dose16 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of xofen 16mg tablet sr

✅ Common Side Effects

Indigestion (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Nausea (Common (5-10%))
Take with a meal. Avoid fatty or spicy foods. Consult doctor if severe.
Headache (Common (5-10%))
Rest and stay hydrated. If headache persists or is severe, contact your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe or persistent, seek medical advice.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe abdominal pain.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor immediately.
Liver toxicity (Rare (<0.1%))
Seek medical attention if you experience yellowing of skin or eyes, dark urine, or severe fatigue.
Severe skin reactions (Very rare (<0.01%))
Stop the medicine and seek emergency care if you develop a rash, blisters, or peeling skin.
Cardiovascular events (Rare (<0.1%))
Seek immediate help if you experience chest pain, shortness of breath, or weakness on one side of the body.

⚠️ Rare Side Effects

Anaphylaxis
Call emergency services immediately if you have difficulty breathing, swelling of face or throat, or a severe rash.
Aseptic meningitis
Seek immediate medical attention if you experience severe headache, fever, stiff neck, or sensitivity to light.
Pancreatitis
Go to the emergency room if you have severe upper abdominal pain that radiates to your back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Other NSAIDs Major
Lithium Major
Methotrexate Major
ACE inhibitors Moderate
Diuretics Moderate
Corticosteroids Moderate
SSRIs Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Other NSAIDs
  • Lithium
  • Methotrexate

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Corticosteroids
  • SSRIs

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may worsen side effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to lornoxicam or other NSAIDs","Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney impairment","Severe liver impairment","Third trimester of pregnancy","Children under 18 years (safety not established)","History of asthma, urticaria, or allergic reactions to aspirin or NSAIDs"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use if you have active bleeding or bleeding disorders.","Use with caution in elderly patients due to increased risk of side effects.","Monitor kidney and liver function during long-term use.","Do not exceed the recommended dose.","Inform your doctor if you are taking blood thinners or other NSAIDs.","Stop use and seek medical help if you experience signs of allergic reaction."]

🤱 Lactation Safety

Lornoxicam is excreted in breast milk in small amounts. It is not recommended during breastfeeding unless the potential benefit outweighs the risk. Consult your doctor before use.

💊 Overdose Management

Overdose of lornoxicam may cause symptoms such as nausea, vomiting, abdominal pain, dizziness, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be administered if the overdose is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always take this medicine with food or a glass of milk to reduce the risk of stomach upset. Do not crush, chew, or break the sustained-release tablet; swallow it whole. Avoid alcohol while taking this medicine as it can increase the risk of gastrointestinal bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor, as this can increase the risk of side effects. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, high blood pressure, or heart disease. Use the lowest effective dose for the shortest duration possible. Do not stop taking this medicine abruptly without consulting your doctor, especially if you have been on long-term therapy. Keep all appointments for monitoring blood tests as advised by your healthcare provider.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose and monitor closely. Avoid long-term use unless necessary.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are not recommended during the third trimester. Use effective contraception if appropriate.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but it can increase bleeding risk. Inform your surgeon if you are taking it. It may need to be stopped before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it can increase bleeding during dental procedures. Your dentist may advise stopping it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture and ergonomics.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables.
🧘
Get adequate sleep to aid recovery.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Avoid high-impact exercises that may worsen joint pain. Consult your physiotherapist for safe exercises. Stop exercise if you experience severe pain, dizziness, or shortness of breath.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce processed and fried foods.
Stay well hydrated.
Eat plenty of fruits and vegetables rich in antioxidants.
Limit sugar and refined carbohydrates.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Inform your employer if your work involves operating machinery.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, especially if you have been on long-term therapy. Your doctor may taper the dose gradually. If you experience serious side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor if you need to use it for more than a few weeks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Topical NSAIDs

May provide localized pain relief with fewer systemic side effects.

Evidence: Well-established
Acupuncture

May help reduce pain in some patients.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule in consultation with your doctor. Declare it at customs if required. Keep enough supply for the entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old retired teacher with rheumatoid arthritis
Was prescribed this medicine for joint pain and swelling. After 1 month, experienced relief but also mild indigestion. Doctor advised taking it with meals and added a stomach-protecting medicine.
💡 Lesson: Always report side effects to your doctor; adjustments can be made to improve tolerability.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for xofen 16mg tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure arthritis.
    Fact: This medicine only relieves pain and inflammation; it does not cure arthritis.
  • Myth: It is safe to take this medicine on an empty stomach.
    Fact: Taking it with food reduces the risk of stomach upset and bleeding.
  • Myth: You can stop taking this medicine abruptly.
    Fact: Always consult your doctor before stopping, especially after long-term use.

🔄 Alternative Options

Generic Alternatives

  • Lornoxicam 16mg tablet

Brand Alternatives

  • Aslor 16mg Tablet SR

📊 Comparison with Similar Medicines

[{"medicine":"Lornoxicam","class":"Oxicam NSAID","half_life":"3-4 hours","common_uses":"Arthritis, acute pain"},{"medicine":"Piroxicam","class":"Oxicam NSAID","half_life":"30-86 hours","common_uses":"Arthritis"},{"medicine":"Meloxicam","class":"Oxicam NSAID","half_life":"15-20 hours","common_uses":"Arthritis"},{"medicine":"Diclofenac","class":"Acetic acid NSAID","half_life":"1-2 hours","common_uses":"Arthritis, acute pain"}]

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