welminic ls syrup - Ambroxol (30mg) + Levosalbutamol (0.5mg) medicine

Kofcross L Syrup: Complete Medicine Guide

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🏭 Delcure Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination in productive cough with bronchospasm.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening of breathing after taking the medicine
  • Swelling of face, lips, tongue, or throat
  • Chest pain or irregular heartbeat
  • Severe dizziness or fainting
  • Blood in sputum or vomit
  • Severe skin rash or blisters
  • Yellowing of eyes or skin

If experiencing severe symptoms, call emergency services immediately.

What is welminic ls syrup used for?

This medicine is a combination syrup of Ambroxol and Levosalbutamol used to treat productive cough with bronchospasm. It works by thinning mucus and relaxing airways. It is available by prescription and should be taken as directed by a doctor.

  • Generic Name: Ambroxol (30mg) + Levosalbutamol (0.5mg)
  • Manufacturer: Delcure Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 welminic ls syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एम्ब्रोक्सोल और लेवोसाल्बुटामोल का संयोजन है, जिसका उपयोग बलगम वाली खांसी और सांस की नली में सिकुड़न के इलाज के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है और सांस की नली को फैलाकर सांस लेने में आसानी प्रदान करती है। यह दवा ब्रोंकाइटिस, सीओपीडी और अस्थमा जैसी स्थितियों में उपयोगी है। इसे डॉक्टर के परामर्श के बिना नहीं लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, सिरदर्द, चक्कर आना, कंपन, धड़कन बढ़ना और बेचैनी शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, छाती में दर्द, अनियमित धड़कन, या चेहरे, होंठ, जीभ या गले में सूजन हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही माप के लिए मापने वाला कप या चम्मच का उपयोग करें। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह, थायरॉइड की समस्या, या लीवर या किडनी की बीमारी है तो अपने डॉक्टर को बताएं। इस दवा को लेने के बाद चक्कर आने या कंपन होने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 welminic ls syrup Uses & Benefits

[{"condition":"Productive cough associated with acute bronchitis","description":"Helps loosen thick mucus and relax airways, making it easier to cough out sputum and breathe more comfortably.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD) with mucus hypersecretion","description":"Provides bronchodilation and improves mucus clearance, reducing breathlessness and cough frequency.","evidence":"Well-established"},{"condition":"Asthma with excessive mucus production","description":"Used as an adjunct to controller therapy to relieve bronchospasm and thin mucus, but not for acute severe attacks.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Post-operative pulmonary complications prevention","description":"Sometimes used to prevent mucus plugging after surgery, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Productive cough with bronchospasm

Also treats: Acute bronchitis, Chronic obstructive pulmonary disease (COPD), Asthma

📋 Drug Information

Generic Name(s)Ambroxol (30mg) + Levosalbutamol (0.5mg)
Brand Namewelminic ls syrup
ManufacturerDelcure Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight. Do not freeze. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture. Do not use after the expiry date printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine only for productive cough with bronchospasm, not for dry cough.
2
Advise patients to take it with food to minimize stomach upset.
3
Warn patients about the possibility of tremor and dizziness; advise caution while driving.
4
Monitor potassium levels if used with diuretics or corticosteroids.
5
Instruct patients not to exceed the recommended dose and to complete the course as prescribed.
6
Use with caution in patients with cardiovascular disease, diabetes, or hyperthyroidism.
7
Advise patients to report any worsening of breathing or allergic reactions immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Wheezing and breathlessness
This medicine helps relax airways.
Likely Use
❌
Dry cough
This medicine is not for dry cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevosalbutamol is rapidly absorbed from the gastrointestinal tract after oral administration. Ambroxol is also well absorbed orally. However, oral bioavailability of Levosalbutamol is reduced due to first-pass metabolism. Specific absorption data for this combination syrup is not established from the available information.
DistributionBoth drugs are distributed widely in the body. Levosalbutamol crosses the placenta and is excreted in breast milk. Ambroxol also crosses the placental barrier and enters breast milk. Protein binding information for the combination is not established from the available information.
Protein BindingLevosalbutamol is approximately 50% bound to plasma proteins. Ambroxol binding is not well established. Not established from the available information for the combination.
MetabolismLevosalbutamol is metabolized in the liver primarily by sulfation. Ambroxol is metabolized in the liver by conjugation. Specific metabolic pathways for the combination are not established from the available information.
Half-LifeThe elimination half-life of Levosalbutamol is approximately 3 to 4 hours. The half-life of Ambroxol is approximately 7 to 12 hours. Not established from the available information for the combination.
ExcretionLevosalbutamol and its metabolites are excreted mainly in the urine. Ambroxol is excreted primarily in the urine as metabolites. Not established from the available information for the combination.
BioavailabilityOral bioavailability of Levosalbutamol is approximately 40% due to first-pass metabolism. Bioavailability of Ambroxol is about 70-80%. Not established from the available information for the combination.
Onset of ActionBronchodilation from Levosalbutamol typically begins within 15 to 30 minutes after oral administration. Ambroxol's mucolytic effect may take several hours to become noticeable. Not established from the available information for the combination.
Peak Plasma TimePeak plasma concentration of Levosalbutamol is reached in about 1 to 2 hours. For Ambroxol, peak levels occur in about 1 to 3 hours. Not established from the available information for the combination.
Duration of ActionBronchodilation from Levosalbutamol lasts about 4 to 6 hours. Ambroxol's effect on mucus may last longer. Not established from the available information for the combination.

How It Works

This medicine combines two active ingredients with complementary actions. Ambroxol works by increasing the production of serous fluid in the airways and reducing mucus viscosity, which helps clear thick secretions. Levosalbutamol selectively stimulates beta-2 adrenergic receptors in the bronchial smooth muscle, causing relaxation and widening of the airways. Together, they improve airflow and ease the removal of mucus.

Mechanism Steps

1
Levosalbutamol binds to beta-2 receptors: Levosalbutamol selectively binds to beta-2 adrenergic receptors on bronchial smooth muscle cells, triggering a signaling cascade.
2
Bronchial smooth muscle relaxation: This binding increases cyclic AMP levels, leading to relaxation of the smooth muscles and widening of the airways.
3
Ambroxol acts on mucus: Ambroxol stimulates serous cells and reduces the viscosity of mucus by breaking down acidic mucopolysaccharides, making it easier to expel.
4
Enhanced mucociliary clearance: The combined effect improves the movement of mucus out of the airways, reducing cough and congestion.

💡 How to Take welminic ls syrup

Strength: Each 5 mL of syrup contains Ambroxol 30 mg and Levosalbutamol 0.5 mg.

1Shake the bottle well before each use.
2Use a proper measuring cup or spoon to measure the dose accurately.
3Take the medicine orally with or without food.
4Swallow the syrup slowly; do not mix with other liquids unless advised.
5Wash the measuring cup after each use.
6Close the bottle tightly after use.

Dosage Information

Adult DosageThe usual adult dose is 5 to 10 mL (one to two teaspoons) three times a day, or as prescribed by your doctor. Dose may vary depending on the severity of the condition and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on the child's age and weight.
Elderly DosageElderly patients may be more sensitive to the cardiovascular effects of Levosalbutamol. Use with caution and lower doses may be considered. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with severe renal impairment. Dose adjustment may be needed. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with severe hepatic impairment. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 30 mL (6 teaspoons) per day, but this may vary based on medical advice. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase dizziness and cardiovascular side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of welminic ls syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce stomach upset. If nausea persists, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe or persistent.
Tremor (Common (5-10%))
Usually decreases with continued use. Avoid driving if shaky. Consult doctor if bothersome.
Palpitations (Common (5-10%))
Report to your doctor if you feel your heart racing or pounding.
Dizziness (Common (5-10%))
Avoid sudden movements. Do not drive or operate machinery until you feel normal.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, itching, swelling of face, lips, tongue, or throat, or difficulty breathing.
Paradoxical bronchospasm (Rare (<0.1%))
If breathing becomes worse after taking this medicine, stop it and seek immediate medical attention.
Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you experience irregular heartbeat, chest pain, or fainting.
Hypokalemia (Rare (<0.1%))
Report muscle weakness, cramps, or palpitations to your doctor. Blood tests may be needed.

⚠️ Rare Side Effects

Severe skin reactions (Stevens-Johnson syndrome)
Seek immediate medical attention if you develop rash, blisters, or peeling skin.
Liver enzyme elevation
Report yellowing of eyes or skin, dark urine, or abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Furosemide Moderate
Digoxin Moderate
Corticosteroids Moderate
Ipratropium Minor
Other sympathomimetics Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide, thiazides)
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Ambroxol, Levosalbutamol, or any component of the formulation","Severe cardiovascular disease including severe hypertension and arrhythmias","Hyperthyroidism","Diabetes mellitus (uncontrolled)","Severe hepatic or renal impairment"]

⚠️ Warnings & Precautions

["Do not use for dry cough or cough due to acid reflux.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with heart disease, hypertension, diabetes, or hyperthyroidism.","Do not exceed the recommended dose.","Keep out of reach of children.","If symptoms persist beyond 7 days, consult your doctor.","Do not use with other cough and cold medicines without medical advice."]

🤱 Lactation Safety

Levosalbutamol and Ambroxol are excreted in breast milk. Caution is advised. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe tachycardia, tremor, palpitations, nausea, and hypokalemia. Seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac and electrolyte status.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Shake the bottle well before each use. Use a proper measuring cup or spoon to ensure accurate dosing. Avoid taking this medicine with other cough and cold medicines without consulting your doctor. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or liver or kidney disease. Do not drive or operate heavy machinery if you feel dizzy or shaky after taking this medicine. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. Do not use after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to cardiovascular side effects like palpitations and arrhythmias. Use with caution and lower doses may be considered. Monitor heart rate and blood pressure regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy if you are taking this medicine. The safety of this combination during pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

This medicine may be used after surgery to prevent mucus plugging, but only under medical supervision. Inform your surgeon and anesthesiologist about all medicines you are taking.

🦷 Dental Procedures

No specific precautions for dental procedures, but inform your dentist about this medicine. If you experience dizziness, avoid driving to the appointment.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to keep airways moist.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Practice deep breathing exercises to improve lung function.
🧘
Get plenty of rest to aid recovery.
🌞
Wash hands frequently to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy, shaky, or have palpitations. Light activity like walking may be beneficial, but consult your doctor before starting any exercise routine.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Avoid cold and sugary drinks that may thicken mucus.
Eat a balanced diet rich in fruits and vegetables.
Limit processed foods and dairy if they worsen mucus.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremor, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take rest if you feel unwell.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use of Levosalbutamol may lead to tolerance and reduced effectiveness. Ambroxol is generally well tolerated. Regular monitoring of heart rate, blood pressure, and potassium levels may be needed. Do not use for longer than prescribed without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and soothe airways.

Evidence: Well-established
Chest physiotherapy

Techniques to help clear mucus from the lungs.

Evidence: Well-established
Saline nasal irrigation

Can help with nasal congestion but not a substitute for this medicine.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Ensure you are up to date with influenza and pneumococcal vaccines if you have chronic respiratory conditions. This medicine does not interact with vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep it in your carry-on luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis and thick mucus
He was prescribed this medicine three times a day. After two days, he noticed that his cough became more productive and breathing was easier. He took it with food to avoid stomach upset and completed the 5-day course as advised.
💡 Lesson: Taking the medicine with food improves tolerability, and completing the course helps resolve the infection-related symptoms.
👤 A 60-year-old woman with COPD exacerbation
She experienced relief from breathlessness and could cough out mucus more easily. She was advised to monitor her heart rate and report any palpitations. She avoided alcohol and took the medicine regularly.
💡 Lesson: Regular use as prescribed and monitoring for side effects are important, especially in elderly patients with comorbidities.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to feel relief from breathlessness within 30 minutes, but the full effect on mucus may take a few hours to a day.

Q: Can I take it with other cough medicines?

A: Do not take with other cough and cold medicines without consulting your doctor, as it may lead to overdose or interactions.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician for appropriate use.

Q: What if I take too much?

A: Seek immediate medical attention. Overdose can cause severe palpitations, tremor, and low potassium levels.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for welminic ls syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any type of cough.
    Fact: It is only for productive cough with bronchospasm. It is not for dry cough.
  • Myth: It is safe to take without a prescription.
    Fact: It is a prescription medicine and should only be taken under medical supervision.
  • Myth: More dose means faster relief.
    Fact: Taking more than the prescribed dose can cause serious side effects. Always follow the prescribed dose.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Levosalbutamol syrup (generic)

Brand Alternatives

  • Kofcross L Syrup

📊 Comparison with Similar Medicines

[{"medicine":"Ambroxol + Levosalbutamol","composition":"Ambroxol 30mg + Levosalbutamol 0.5mg per 5mL","uses":"Productive cough with bronchospasm","notes":"Combination provides mucolytic and bronchodilator action."},{"medicine":"Ambroxol + Salbutamol","composition":"Ambroxol 30mg + Salbutamol 2mg per 5mL","uses":"Productive cough with bronchospasm","notes":"Salbutamol is a racemic mixture; Levosalbutamol is the active isomer."}]

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