ventrox pd tablet - Roxithromycin (NA) medicine

Roxithromycin Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Satven And Mer 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe or bloody diarrhea
  • Yellowing of skin or eyes
  • Palpitations or fainting
  • Severe abdominal pain
  • Decreased urine output
  • Rash with fever

If experiencing severe symptoms, call emergency services immediately.

What is ventrox pd tablet used for?

Roxithromycin is a macrolide antibiotic used to treat bacterial infections such as pneumonia, bronchitis, skin infections, and certain sexually transmitted infections. It works by stopping bacterial protein synthesis. The usual adult dose is 150 mg twice daily or 300 mg once daily, taken orally for 5-10 days. It should not be used for viral infections like the common cold.

  • Generic Name: Roxithromycin (NA)
  • Manufacturer: Satven And Mer
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ventrox pd tablet के बारे में (Hindi Summary)

उपयोग: यह दवा रोक्सिथ्रोमाइसिन नामक एंटीबायोटिक है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह श्वसन तंत्र के संक्रमण, त्वचा के संक्रमण, दांतों के संक्रमण और कुछ यौन संचारित संक्रमणों के लिए प्रभावी है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए काम नहीं करती।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लिवर की सूजन और अनियमित दिल की धड़कन हो सकती है। यदि आपको पीलिया, गहरे रंग का पेशाब, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। इस दवा के साथ शराब न लें। यदि आपको लिवर या दिल की समस्या है तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ventrox pd tablet Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used to treat bacterial pneumonia caused by susceptible organisms such as Streptococcus pneumoniae and Mycoplasma pneumoniae.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Prescribed for bacterial bronchitis when antibiotics are indicated.","evidence":"Established"},{"condition":"Skin and soft tissue infections","description":"Effective against many skin infections caused by Staphylococcus aureus and Streptococcus pyogenes.","evidence":"Established"},{"condition":"Urethritis and cervicitis","description":"Used to treat infections caused by Chlamydia trachomatis and Ureaplasma urealyticum.","evidence":"Well-established"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and periodontitis as an alternative to penicillin.","evidence":"Established"}]

Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes included in combination regimens for H. pylori, though not first-line.","evidence":"Limited"},{"condition":"Lyme disease","description":"May be used as an alternative in early localized Lyme disease, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Skin infections, Sexual transmitted infections, Dental infections

📋 Drug Information

Generic Name(s)Roxithromycin (NA)
Brand Nameventrox pd tablet
ManufacturerSatven And Mer
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMacrolides
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at evenly spaced intervals to maintain blood levels.
2
Complete the full course even if symptoms improve after a few days.
3
Inform your doctor if you have a history of heart rhythm problems.
4
Avoid taking antacids within 2 hours of this medicine.
5
Report any signs of liver problems like yellowing of eyes or dark urine.
6
Do not use leftover antibiotics for future infections.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough
This medicine is commonly prescribed for respiratory infections.
Likely Use
✅
Skin rash with pus
May be used for bacterial skin infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRoxithromycin is rapidly absorbed from the gastrointestinal tract after oral administration. Absorption is not significantly affected by food. The absolute bioavailability is approximately 50%.
DistributionRoxithromycin is widely distributed in the body. It penetrates well into respiratory tissues, tonsils, skin, and soft tissues. It also achieves high concentrations in phagocytes, which may help deliver the drug to sites of infection.
Protein BindingRoxithromycin is approximately 86-96% bound to plasma proteins, primarily to alpha-1-acid glycoprotein and albumin.
MetabolismRoxithromycin undergoes limited metabolism in the liver. Only a small fraction is metabolized, primarily by CYP3A4, to inactive metabolites.
Half-LifeThe elimination half-life of roxithromycin is approximately 10-12 hours in healthy adults.
ExcretionRoxithromycin is excreted mainly unchanged in the feces via biliary elimination. A smaller portion is excreted in the urine.
BioavailabilityThe oral bioavailability of roxithromycin is approximately 50%.
Onset of ActionThe onset of action is typically within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma TimePeak plasma concentrations are reached approximately 2 hours after oral administration.
Duration of ActionThe duration of action is approximately 12-24 hours, allowing for once or twice daily dosing.

How It Works

Roxithromycin is a semi-synthetic macrolide antibiotic. It binds reversibly to the 50S ribosomal subunit of susceptible bacteria, specifically to the 23S rRNA component of the 50S subunit. This binding inhibits the translocation step of protein synthesis, preventing the elongation of polypeptide chains. As a result, bacterial protein synthesis is halted, leading to inhibition of bacterial growth and replication. Roxithromycin is primarily bacteriostatic but can be bactericidal at high concentrations against certain organisms.

Mechanism Steps

1
Binding to 50S ribosomal subunit: Roxithromycin binds reversibly to the 23S rRNA of the bacterial 50S ribosomal subunit.
2
Inhibition of translocation: This binding blocks the translocation of peptidyl-tRNA from the A site to the P site on the ribosome.
3
Prevention of protein elongation: As a result, the growing polypeptide chain cannot be elongated, and protein synthesis is halted.
4
Inhibition of bacterial growth: Without essential proteins, bacteria cannot grow or multiply, leading to their eventual death or inhibition.

💡 How to Take ventrox pd tablet

Strength: Roxithromycin is available as 150 mg and 300 mg immediate-release tablets.

1Take this medicine by mouth with a full glass of water.
2You can take it with or without food.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.

Dosage Information

Adult DosageThe usual adult dose of roxithromycin is 150 mg twice daily or 300 mg once daily, depending on the type and severity of infection. For severe infections, the dose may be increased to 300 mg twice daily. The duration of treatment varies from 5 to 10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. No specific dose reduction is generally needed unless renal impairment is present. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance <30 mL/min), the dose may need to be reduced. Consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, roxithromycin should be used with caution. Dose reduction may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 600 mg (300 mg twice daily).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with or without food
Food does not significantly affect absorption.
Grapefruit juice
Avoid
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ventrox pd tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food to reduce nausea. If persistent, consult your doctor.
Diarrhea (Common (1-10%))
Stay hydrated. If severe or bloody, seek medical advice.
Abdominal pain (Common (1-10%))
Usually resolves. If severe, contact your doctor.
Headache (Common (1-10%))
Rest and hydrate. If persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or rash.
Liver inflammation (hepatitis) (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain immediately.
QT prolongation and arrhythmias (Rare (<0.1%))
Seek medical attention if you experience palpitations, dizziness, or fainting.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop severe, persistent diarrhea, especially with blood or mucus.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention if you experience severe upper abdominal pain radiating to the back.
Interstitial nephritis
Report decreased urine output, swelling, or fatigue to your doctor.
Seizures
Seek emergency medical help if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ergotamine Major
Terfenadine Major
Simvastatin Major
Carbamazepine Moderate
Cyclosporine Moderate
Digoxin Moderate
Theophylline Moderate
Antacids Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Ergot alkaloids (e.g., ergotamine, dihydroergotamine)
  • Terfenadine, astemizole, cisapride
  • Warfarin
  • Statins (e.g., simvastatin, atorvastatin)

⚡ Moderate Interactions

  • Carbamazepine
  • Cyclosporine
  • Digoxin
  • Theophylline

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to roxithromycin or other macrolides","Severe liver disease","Concomitant use with ergot alkaloids","Concomitant use with terfenadine, astemizole, or cisapride","History of QT prolongation or ventricular arrhythmias"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver impairment; monitor liver function.","May prolong QT interval; avoid in patients with known QT prolongation.","Caution in patients with myasthenia gravis as macrolides may worsen symptoms.","Superinfection with resistant organisms may occur; monitor.","Avoid concomitant use with other QT-prolonging drugs.","Adjust dose in severe renal impairment."]

🤱 Lactation Safety

Roxithromycin is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor to weigh benefits and risks.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, diarrhea, and hearing loss. There is no specific antidote. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better. Avoid alcohol while taking this medicine as it may increase stomach upset. Inform your doctor if you have liver or heart problems before starting this medicine. Do not share this medicine with others. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects and drug interactions. Dose adjustment may be needed based on renal function. Monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant or planning pregnancy. Roxithromycin is generally considered safe but use only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics or other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may be used for dental infections but can interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest to help your body fight infection.
🥗
Stay well hydrated by drinking water and fluids.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Avoid close contact with others to prevent spread of infection.
🧘
Practice good hand hygiene.

🏋️ Exercise Considerations

Rest is recommended during acute infection. Gradually resume exercise as you recover. Avoid strenuous activity if you feel dizzy or weak.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to prevent diarrhea.
Avoid spicy and oily foods that may upset your stomach.
Drink plenty of water.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

You may feel tired or dizzy; avoid driving or operating heavy machinery until you know how this medicine affects you. Take sick leave if needed.

🛑 When to Stop This Medicine

Stop only after completing the full prescribed course. Do not stop early even if you feel better. Consult your doctor if you experience severe side effects.

📅 Long-Term Use Effects

Long-term use of roxithromycin may lead to bacterial resistance and superinfection. It is not intended for prolonged use unless directed by a doctor. Monitor liver function if used for more than 2 weeks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Azithromycin

Another macrolide with similar uses but different dosing.

Evidence: Well-established
Amoxicillin

A penicillin antibiotic for bacterial infections if not allergic.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics do not interact with vaccines. However, if you are acutely ill, vaccination may be postponed until you recover.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying antibiotics.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with community-acquired pneumonia
He was prescribed roxithromycin 150 mg twice daily for 7 days. He noticed improvement in fever and cough within 3 days. He completed the full course and recovered fully. He was advised to take it with food to avoid stomach upset.
💡 Lesson: Completing the full antibiotic course is essential to prevent relapse and resistance.
👤 A 28-year-old woman with chlamydia infection
She was treated with roxithromycin 300 mg once daily for 7 days. She experienced mild nausea but completed the treatment. Her symptoms resolved, and follow-up tests were negative.
💡 Lesson: Roxithromycin is effective for chlamydial infections when taken as prescribed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-2 days, but complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, you can take it with or without food.

Q: What if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip it. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ventrox pd tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Roxithromycin can cure the common cold.
    Fact: Roxithromycin is an antibiotic and is ineffective against viruses, including those causing the common cold.
  • Myth: You can stop taking roxithromycin once you feel better.
    Fact: You must complete the full prescribed course to prevent bacterial resistance and recurrence of infection.
  • Myth: Roxithromycin is safe for everyone.
    Fact: It is not safe for people with known macrolide allergy, severe liver disease, or certain heart conditions.

🔄 Alternative Options

Generic Alternatives

  • Roxithromycin 150 mg tablet
  • Roxithromycin 300 mg tablet

Brand Alternatives

  • Roxid
  • Roxee
  • Roxifree
  • Roxomycin

📊 Comparison with Similar Medicines

[{"medicine":"Roxithromycin","class":"Macrolide","half_life":"10-12 hours","dosing":"Once or twice daily","common_uses":"Respiratory, skin, STI"},{"medicine":"Azithromycin","class":"Macrolide","half_life":"68 hours","dosing":"Once daily","common_uses":"Respiratory, STI, otitis media"},{"medicine":"Clarithromycin","class":"Macrolide","half_life":"3-4 hours","dosing":"Twice daily","common_uses":"Respiratory, H. pylori, skin"}]

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