vagi vaginal cream - Tinidazole (5% w/w) + Clotrimazole (2% w/w) medicine

Infa VT Ointment: Complete Medicine Guide

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🏭 Rekvina Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for mixed skin infections; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
  • Severe skin reaction: blistering, peeling, or extensive rash.
  • Signs of systemic absorption: nausea, vomiting, metallic taste, headache.
  • No improvement after completing the prescribed course.
  • Infection worsens or spreads to other areas.
  • Development of new symptoms such as fever or chills.

If experiencing severe symptoms, call emergency services immediately.

What is vagi vaginal cream used for?

This medicine is a topical ointment containing tinidazole 5% w/w and clotrimazole 2% w/w. It is used to treat mixed bacterial and fungal skin infections. Apply a thin layer to the affected area as directed by your doctor, usually once or twice daily. Avoid alcohol during treatment.

  • Generic Name: Tinidazole (5% w/w) + Clotrimazole (2% w/w)
  • Manufacturer: Rekvina Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 vagi vaginal cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल ऑइंटमेंट है जिसमें टिनिडाजोल 5% w/w और क्लोट्रिमाजोल 2% w/w शामिल हैं। यह मुख्य रूप से त्वचा के उन संक्रमणों के इलाज के लिए उपयोग की जाती है जिनमें बैक्टीरिया और फंगस दोनों शामिल होते हैं। इसे प्रभावित जगह पर पतली परत में लगाएं, जैसा डॉक्टर ने बताया हो। आमतौर पर इसे दिन में एक या दो बार लगाया जाता है। इसका इस्तेमाल डॉक्टर की सलाह के बिना न करें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभाव आमतौर पर हल्के होते हैं और लगाने की जगह तक सीमित रहते हैं। इसमें जलन, खुजली, लालिमा या हल्की सूजन हो सकती है। ये लक्षण आमतौर पर कुछ समय में ठीक हो जाते हैं। अगर त्वचा पर गंभीर प्रतिक्रिया हो, जैसे छाले पड़ना या तेज दर्द, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को बताएं यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं। इसे आंखों, कानों या म्यूकस मेम्ब्रेन पर न लगाएं। लगाने से पहले और बाद में हाथ धोएं। इसे बच्चों की पहुंच से दूर रखें। शराब का सेवन बिल्कुल न करें क्योंकि इससे प्रतिक्रिया हो सकती है।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 vagi vaginal cream Uses & Benefits

[{"condition":"Mixed bacterial and fungal skin infections","description":"This medicine is used to treat skin infections that involve both anaerobic bacteria and fungi, such as infected dermatitis or intertrigo.","evidence":"Moderate"},{"condition":"Bacterial vaginosis (when applied intravaginally as directed)","description":"Tinidazole is effective against Gardnerella vaginalis and other anaerobes, while clotrimazole addresses concurrent yeast infections.","evidence":"Limited"},{"condition":"Candidal skin infections with secondary bacterial involvement","description":"Clotrimazole treats the fungal component, and tinidazole targets susceptible bacteria, providing broad coverage.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Prevention of infection after minor skin trauma","description":"Sometimes used off-label to prevent infection in minor cuts or abrasions, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Mixed bacterial and fungal skin infections

Also treats: Candidal skin infections, Bacterial vaginosis (when used intravaginally as directed)

📋 Drug Information

Generic Name(s)Tinidazole (5% w/w) + Clotrimazole (2% w/w)
Brand Namevagi vaginal cream
ManufacturerRekvina Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the tube tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply the ointment exactly as prescribed by your doctor, usually once or twice daily.
2
Wash and dry the affected area before applying the ointment.
3
Avoid using this medicine on large areas of broken skin unless specifically instructed.
4
Do not cover the treated area with airtight dressings unless your doctor advises otherwise.
5
Avoid alcohol consumption during treatment and for at least 72 hours after stopping.
6
Complete the full course of treatment even if symptoms improve early.
7
If you experience severe irritation or allergic reaction, stop using and consult your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Skin redness and itching
This medicine is commonly prescribed for mixed skin infections.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information for topical application. Systemic absorption is generally minimal when applied to intact skin, but may occur if applied to large areas or broken skin.
DistributionNot established from the available information for topical application.
Protein BindingNot established from the available information for topical application.
MetabolismNot established from the available information for topical application. Systemically absorbed tinidazole is metabolized in the liver, and clotrimazole is metabolized in the liver.
Half-LifeNot established from the available information for topical application.
ExcretionNot established from the available information for topical application.
BioavailabilityNot established from the available information for topical application.
Onset of ActionNot established from the available information for topical application.
Peak Plasma TimeNot established from the available information for topical application.
Duration of ActionNot established from the available information for topical application.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Tinidazole is a nitroimidazole that enters susceptible anaerobic microorganisms and protozoa, where its nitro group is reduced to reactive intermediates. These intermediates damage microbial DNA, leading to cell death. Clotrimazole is an imidazole antifungal that inhibits the enzyme lanosterol 14-alpha-demethylase, which is required to convert lanosterol to ergosterol, a vital component of fungal cell membranes. This inhibition increases membrane permeability and causes leakage of cellular contents, resulting in fungal cell death. Together, they provide antimicrobial and antifungal action at the site of application.

Mechanism Steps

1
Tinidazole uptake and activation: Tinidazole diffuses into anaerobic microorganisms, where its nitro group is reduced by ferredoxin-like electron transport proteins, creating reactive cytotoxic intermediates.
2
DNA damage by tinidazole: The reactive intermediates bind to and damage microbial DNA, causing strand breakage and inhibition of nucleic acid synthesis, which leads to cell death.
3
Clotrimazole inhibition of ergosterol synthesis: Clotrimazole binds to and inhibits lanosterol 14-alpha-demethylase, blocking the conversion of lanosterol to ergosterol, a key component of fungal cell membranes.
4
Fungal membrane disruption: The depletion of ergosterol and accumulation of abnormal sterols increase membrane permeability, causing leakage of essential cellular components and fungal cell death.

💡 How to Take vagi vaginal cream

Strength: Ointment containing Tinidazole 5% w/w and Clotrimazole 2% w/w.

1Wash your hands thoroughly before and after applying the ointment.
2Clean and dry the affected area gently.
3Apply a thin layer of the ointment to the affected area as directed.
4Rub it in gently if instructed, or leave a thin film as advised.
5Do not cover the area with airtight dressings unless told to do so.
6Avoid contact with eyes, mouth, and other mucous membranes.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area as directed by your doctor, usually once or twice daily. The exact frequency and duration depend on the type and severity of the infection. Wash and dry the area before application. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustments are established for elderly patients. Use with caution and under medical supervision.
Renal ImpairmentNo specific dose adjustments are established for topical use in renal impairment. Consult your doctor.
Hepatic ImpairmentNo specific dose adjustments are established for topical use in hepatic impairment. Use with caution and consult your doctor.
Maximum Daily DoseNot established from the available information. Follow your doctor's prescription.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of vagi vaginal cream

✅ Common Side Effects

Application site irritation (Common (1-10%))
Usually resolves on its own. If it persists or worsens, consult your doctor.
Burning sensation at application site (Common (1-10%))
May decrease with continued use. If severe, stop and consult your doctor.
Itching (Common (1-10%))
Avoid scratching. If itching is intense, consult your doctor.
Redness (Common (1-10%))
Usually temporary. If redness spreads or becomes painful, seek medical advice.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, throat, difficulty breathing, or a severe rash.
Severe skin reaction (e.g., blistering, peeling) (Rare (<0.1%))
Stop using the ointment and seek immediate medical attention.

⚠️ Rare Side Effects

Systemic effects from absorption (nausea, metallic taste, headache)
Consult your doctor if these occur, especially if the ointment is applied to large areas.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Topical corticosteroids Moderate
Other topical agents Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • Other topical corticosteroids

🍷 Alcohol Interaction

Avoid alcohol while using this medicine and for at least 72 hours after stopping, as tinidazole can cause a disulfiram-like reaction with symptoms such as flushing, nausea, vomiting, and rapid heartbeat.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to tinidazole, clotrimazole, or any component of the formulation.","Not for ophthalmic use.","Not for oral or intravaginal use unless specifically directed by a healthcare professional."]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes, ears, and mucous membranes.","Do not apply to large areas of broken skin or open wounds without medical advice.","Discontinue use and consult a doctor if irritation or hypersensitivity occurs.","Avoid alcohol during treatment and for 72 hours after stopping due to tinidazole component.","Use with caution in patients with hepatic impairment due to potential systemic absorption.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. It is not known whether tinidazole or clotrimazole are excreted in human milk after topical application. Consult your doctor before use if breastfeeding.

💊 Overdose Management

Overdose with topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of tinidazole overdose may include nausea, vomiting, and neurological effects. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Although topical absorption is low, it is best to use this medicine only if clearly needed and under medical supervision. Avoid applying the ointment to large areas of broken skin or to the eyes, ears, or mucous membranes unless specifically instructed. Do not cover the treated area with airtight dressings unless your doctor advises otherwise, as this can increase absorption and side effects. Wash your hands thoroughly before and after applying the ointment to prevent spreading the infection or contaminating the tube. If you are using other topical products on the same area, consult your pharmacist or doctor to avoid interactions. Keep this medicine out of reach of children. Do not use it for longer than prescribed, and do not share it with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients should use this medicine with caution, as they may be more susceptible to skin irritation and systemic effects if absorption occurs. Consult a doctor for appropriate use.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of topical tinidazole and clotrimazole during pregnancy is not fully established.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine on surgical wounds or around incision sites.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medications you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or personal items that may spread infection.
😴
Wear loose-fitting, breathable clothing to reduce irritation.
💧
Maintain good hygiene practices.
🧘
Manage underlying conditions like diabetes to support healing.

🏋️ Exercise Considerations

No specific exercise restrictions are known. However, avoid activities that may cause excessive sweating or friction on the treated area until it heals.

🥗 Diet Recommendations

Eat a balanced diet rich in vitamins and minerals to support immune function.
Stay well hydrated.
Limit sugary and processed foods that may promote fungal growth.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or discomfort, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if you experience severe irritation, allergic reaction, or if your symptoms worsen. Do not stop prematurely without completing the prescribed course, as this may lead to recurrence.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use may increase the risk of local irritation or allergic reactions. It may also lead to overgrowth of non-susceptible organisms. Regular follow-up with your doctor is recommended if extended treatment is required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Good hygiene practices

Keeping the skin clean and dry can help prevent and manage skin infections.

Evidence: Well-established
Topical corticosteroids (for inflammation)

May be used in combination for inflammatory skin conditions, but only under medical supervision.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. Consult your doctor for routine vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, continue with your regular application schedule as prescribed. Keep it in your carry-on luggage if you need it during the flight. Check customs regulations for carrying topical medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a mixed skin infection on her foot
She was prescribed this ointment for a skin infection that had both fungal and bacterial features. She applied it twice daily as directed. After a week, the redness and itching significantly reduced. She completed the full course and the infection cleared completely.
💡 Lesson: Consistent application and completing the full course are key to resolving mixed infections.
👤 A 50-year-old man with a history of diabetes and a skin infection
He developed a skin infection that was not healing. His doctor prescribed this ointment. He was advised to keep his blood sugar controlled and to apply the ointment regularly. The infection improved over two weeks.
💡 Lesson: Managing underlying conditions like diabetes is important for effective treatment of skin infections.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start noticing improvement within a few days, but it is important to complete the full course as prescribed by your doctor.

Q: Can I use this medicine on my face?

A: Only if your doctor has specifically advised it. Avoid contact with eyes and mucous membranes.

Q: What should I do if I miss a dose?

A: Apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long does it take to work?
  • Is it safe to use during pregnancy?
  • Can I use it with other skin creams?
  • What if I accidentally swallow it?
  • Does it stain clothes?

🔄 Substitutes for vagi vaginal cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any skin infection.
    Fact: This medicine is effective only against susceptible bacteria and fungi. It is not effective against viruses or all types of infections.
  • Myth: You can stop using the ointment as soon as symptoms improve.
    Fact: You should complete the full course as prescribed to prevent recurrence and resistance.

📊 Comparison with Similar Medicines

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