v-gest soft gelatin capsule - Progesterone (200mg) medicine

e-gest 200mg Tablet: Complete Medicine Guide

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Progesterone (200mg)
🏭 Vsaar Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Progesterone is used in pregnancy when clinically indicated, such as for luteal support or to prevent miscarriage in women with progesterone deficiency. It is not classified under the old letter categories. Use during pregnancy should only be under the supervision of a qualified clinician. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for approved indications such as luteal support and menstrual regulation.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden severe headache or vision changes
  • Chest pain or difficulty breathing
  • Calf pain or swelling in one leg
  • Yellowing of the skin or eyes
  • Severe abdominal pain
  • Heavy or unusual vaginal bleeding
  • Swelling of the face, lips, or throat

If experiencing severe symptoms, call emergency services immediately.

What is v-gest soft gelatin capsule used for?

This medicine contains progesterone 200 mg, a hormone used to support the uterine lining, regulate menstrual cycles, and help maintain early pregnancy. It is taken by mouth, usually with food, and should only be used under a doctor's supervision.

  • Generic Name: Progesterone (200mg)
  • Manufacturer: Vsaar Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 v-gest soft gelatin capsule के बारे में (Hindi Summary)

उपयोग: यह दवा प्रोजेस्टेरोन 200 मिलीग्राम की एक गोली है, जिसका उपयोग गर्भाशय की परत को सहारा देने, मासिक धर्म को नियमित करने और शुरुआती गर्भावस्था को बनाए रखने में मदद के लिए किया जाता है। यह उन महिलाओं के लिए दी जाती है जिनमें प्रोजेस्टेरोन की कमी होती है या जो फर्टिलिटी ट्रीटमेंट ले रही हैं। इस दवा को डॉक्टर की सलाह के बिना शुरू या बंद नहीं करना चाहिए।

साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे नींद आना, चक्कर आना, सिरदर्द, स्तनों में कोमलता, जी मिचलाना, पेट में गैस बनना और मूड में बदलाव। गंभीर दुष्प्रभाव कम होते हैं, लेकिन अगर सांस लेने में तकलीफ, सीने में दर्द, पैर में सूजन या दर्द, या त्वचा और आंखों का पीला पड़ना हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लेने से पेट की परेशानी कम होती है और दवा का अवशोषण बेहतर होता है। इस दवा से नींद या चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें। गर्भावस्था, स्तनपान या अन्य दवाओं के बारे में अपने डॉक्टर को जरूर बताएं। दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 v-gest soft gelatin capsule Uses & Benefits

[{"condition":"Luteal phase support in assisted reproduction","description":"Used to support the endometrial lining after ovulation induction or embryo transfer in IVF and other fertility treatments.","evidence":"Well-established"},{"condition":"Threatened or recurrent miscarriage due to progesterone deficiency","description":"Prescribed to support early pregnancy when low progesterone is suspected or documented.","evidence":"Established in selected cases"},{"condition":"Irregular or absent menstrual cycles (oligomenorrhea or amenorrhea)","description":"Helps to induce or regulate bleeding in women with progesterone deficiency.","evidence":"Well-established"},{"condition":"Abnormal uterine bleeding due to hormonal imbalance","description":"Used to stabilize the endometrium and control abnormal bleeding.","evidence":"Established"},{"condition":"Endometrial preparation before certain procedures","description":"May be used to prepare the uterine lining for diagnostic or therapeutic procedures.","evidence":"Limited to specialist use"}]

Off-label uses: [{"condition":"Premenstrual syndrome (PMS)","description":"Sometimes prescribed off-label to reduce severe PMS symptoms, though evidence is mixed.","evidence":"Limited"},{"condition":"Perimenopausal symptoms","description":"Occasionally used off-label to help with hot flushes or mood symptoms when other options are unsuitable.","evidence":"Limited"},{"condition":"Lactation suppression","description":"Rarely used off-label in some settings, but not a first-line approach.","evidence":"Limited"}]

Primary treatment for: Progesterone deficiency conditions

Also treats: Luteal phase defect, Threatened miscarriage, Irregular menstrual cycles, Abnormal uterine bleeding, Infertility

📋 Drug Information

Generic Name(s)Progesterone (200mg)
Brand Namev-gest soft gelatin capsule
ManufacturerVsaar Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassNatural Progesterone
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the tablets in their original container and out of reach of children.
Shelf LifeThe shelf life is typically 24 to 36 months from the date of manufacture, but you should check the expiry date printed on the pack. Do not use the medicine after the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to improve absorption and reduce stomach upset.
2
Take your dose at bedtime if you experience drowsiness during the day.
3
Do not stop this medicine suddenly without consulting your doctor.
4
Inform your doctor about all other medicines, especially rifampicin, carbamazepine, phenytoin, and St John's wort.
5
Avoid alcohol while taking this medicine because it can increase drowsiness.
6
Report any unusual vaginal bleeding, calf pain, or breathing difficulty immediately.
7
Keep all follow-up appointments so your doctor can monitor your response.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Irregular menstrual cycles
This medicine is commonly prescribed for this.
Likely Use
✅
Threatened miscarriage
This medicine may be used to support early pregnancy.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Joint pain
This medicine is not a pain reliever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionProgesterone is absorbed from the gastrointestinal tract after oral administration, but the exact absorption characteristics depend on the formulation and whether it is micronized. Food can increase the absorption of oral progesterone, so it is often recommended to take it with a meal. Specific absorption data for this exact product are not established from the available information.
DistributionProgesterone is highly bound to plasma proteins and is distributed widely into body tissues, including the uterus, breast, and brain. It also crosses the placenta and is found in breast milk. Detailed distribution data for this specific product are not established from the available information.
Protein BindingProgesterone is approximately 96 to 99 percent bound to plasma proteins, mainly albumin and corticosteroid-binding globulin. This high binding is a normal characteristic of the hormone.
MetabolismProgesterone is metabolized primarily in the liver by cytochrome P450 enzymes, including CYP3A4, into several metabolites such as pregnanediol and pregnanolone. These metabolites are then conjugated and excreted. The metabolism can be affected by liver function and by other medicines that influence CYP3A4 activity.
Half-LifeThe elimination half-life of oral progesterone is generally short, in the range of a few hours, but it can vary with the formulation and individual factors. Specific half-life data for this exact product are not established from the available information.
ExcretionProgesterone metabolites are excreted mainly in the urine as glucuronide and sulfate conjugates, with a smaller amount in the feces. This is the normal route of elimination for the hormone.
BioavailabilityThe oral bioavailability of progesterone is low and variable because of extensive first-pass metabolism in the liver. Micronized formulations and taking the medicine with food can improve absorption. Exact bioavailability data for this product are not established from the available information.
Onset of ActionThe onset of action depends on the indication. For endometrial support, effects may take several days to become apparent. For sedation, some people notice drowsiness within one to three hours of taking a dose. Specific onset data for this product are not established from the available information.
Peak Plasma TimePeak plasma levels of oral progesterone are usually reached within a few hours after intake, often around two to four hours, but this can vary with food and formulation. Specific peak time data for this product are not established from the available information.
Duration of ActionThe duration of action depends on the dose and the clinical situation. For hormonal effects on the endometrium, the action lasts as long as the medicine is taken regularly. For sedative effects, drowsiness may last several hours. Specific duration data for this product are not established from the available information.

How It Works

This medicine works by binding to progesterone receptors located in the nucleus of target cells, particularly in the endometrium, myometrium, breast, and brain. Once bound, the progesterone-receptor complex interacts with specific DNA sequences called progesterone response elements, which alters the production of certain proteins. In the uterus, this transforms the endometrium from a proliferative to a secretory state, making it suitable for implantation and helping to maintain early pregnancy. It also reduces uterine muscle contractions and influences the normal hormonal feedback loop to the pituitary gland, which can suppress ovulation when taken in certain regimens. These actions together help to regulate the menstrual cycle and support pregnancy.

Mechanism Steps

1
Binding to progesterone receptor: This medicine enters target cells and binds to the nuclear progesterone receptor.
2
Receptor activation and DNA interaction: The activated receptor complex binds to progesterone response elements on DNA and changes gene transcription.
3
Endometrial transformation: The endometrium changes from a proliferative to a secretory pattern, ready for implantation.
4
Uterine relaxation and feedback: Uterine contractions are reduced and the pituitary release of gonadotropins is modulated.

💡 How to Take v-gest soft gelatin capsule

Strength: This medicine is available as an immediate-release tablet containing 200 mg of progesterone.

1Take this medicine by mouth with a full glass of water.
2Take it with food to improve absorption and reduce stomach upset.
3Swallow the tablet whole; do not crush or chew unless your doctor says it is okay.
4Take it at the same time each day to maintain steady levels.
5If you feel drowsy, take your dose at bedtime.
6Do not stop taking this medicine without talking to your doctor first.

Dosage Information

Adult DosageThe dose of this medicine depends on the condition being treated, your age, your response to treatment, and your liver function. For luteal support, a common regimen is 200 mg to 400 mg daily, often divided into one or two doses, but the exact dose and timing must be individualized by a qualified clinician. For menstrual irregularities, the dose and schedule may be different. Always follow your doctor's prescription exactly and do not change the dose on your own. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageThere is limited information on the use of this medicine in elderly patients. It should be used with caution and under medical supervision, with attention to liver and kidney function. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is established for people with kidney disease. Use with caution and under medical supervision, especially if kidney function is severely reduced.
Hepatic ImpairmentThis medicine is metabolized in the liver, so people with liver disease may need a lower dose or may not be able to take it at all. Dose must be individualized by a qualified clinician based on liver function.
Maximum Daily DoseThe maximum daily dose depends on the indication and your doctor's prescription. Do not exceed the dose prescribed by your doctor. For educational reference, doses up to 400 mg daily are sometimes used, but this must be confirmed by your clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Improves absorption and reduces stomach upset.
Grapefruit
Avoid large amounts
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of v-gest soft gelatin capsule

✅ Common Side Effects

Drowsiness (Common (up to 30%))
Avoid driving or operating machinery until you know how it affects you. Taking the dose at bedtime may help.
Dizziness (Common (10-20%))
Rise slowly from sitting or lying down. If it persists, consult your doctor.
Headache (Common (10-20%))
Stay hydrated and rest. Consult your doctor if headaches are severe or persistent.
Breast tenderness (Common (10-20%))
Wear a supportive bra and apply a warm compress if needed. Report persistent or severe pain.
Nausea (Common (5-10%))
Take the tablet with food. If nausea continues, speak to your doctor.
Bloating (Common (5-10%))
Eat smaller meals and reduce salt intake. Consult your doctor if it becomes bothersome.
Mood changes (Common (5-10%))
Talk to your doctor if mood changes affect your daily life.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you have swelling of the face, lips, tongue, or throat, or difficulty breathing.
Blood clot (deep vein thrombosis or pulmonary embolism) (Rare (<0.1%))
Go to the emergency department if you have calf pain or swelling, chest pain, or sudden shortness of breath.
Severe liver injury (Rare (<0.1%))
Seek medical attention if you notice yellowing of the skin or eyes, dark urine, or severe abdominal pain.
Sudden severe headache or vision changes (Rare (<0.1%))
Contact your doctor immediately or go to the emergency department.
Unusual vaginal bleeding (Uncommon (0.1-1%))
Report any heavy or unexpected bleeding to your doctor without delay.

⚠️ Rare Side Effects

Cholestatic jaundice
Seek medical attention if you notice yellowing of the skin or eyes.
Seizures
Call emergency services if a seizure occurs.
Severe depression
Contact your doctor or a mental health professional immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Rifampicin Major
Carbamazepine Major
Phenytoin Major
St John's wort Major
Ketoconazole Moderate
Itraconazole Moderate
Clarithromycin Moderate
Erythromycin Moderate
Grapefruit juice Moderate
Alcohol Moderate

🚨 Major Interactions

  • Rifampicin
  • Carbamazepine and phenytoin
  • St John's wort

⚡ Moderate Interactions

  • Ketoconazole and itraconazole
  • Clarithromycin and erythromycin
  • Grapefruit juice

🍷 Alcohol Interaction

Alcohol may increase the drowsiness and dizziness caused by this medicine. It is best to avoid alcohol or limit it as much as possible while taking this medicine, especially if you need to drive or operate machinery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to progesterone or any ingredient in the tablet","Unexplained vaginal bleeding","Known or suspected progesterone-sensitive tumor","History of blood clots or active thromboembolic disease","Severe liver disease","Known or suspected pregnancy that is not viable or is being managed without progesterone support","Breastfeeding in the first few weeks after birth unless advised by a doctor"]

⚠️ Warnings & Precautions

["This medicine can cause drowsiness and dizziness. Avoid driving or operating machinery until you know how it affects you.","Tell your doctor if you have a history of blood clots, liver disease, kidney disease, or breast cancer.","Do not use this medicine if you are pregnant unless your doctor has specifically prescribed it for pregnancy support.","Inform your doctor about all other medicines, supplements, and herbal products you are taking, especially rifampicin, carbamazepine, phenytoin, and St John's wort.","Avoid alcohol while taking this medicine because it can increase drowsiness.","If you miss a dose, do not double the next dose. Follow your doctor's advice.","Keep this medicine out of reach of children.","Do not share this medicine with anyone else."]

🤱 Lactation Safety

Progesterone passes into breast milk, but the amounts are generally considered small. It is usually considered compatible with breastfeeding, but you should consult your doctor before using it while breastfeeding, especially in the first few weeks after birth.

💊 Overdose Management

If you take more than the prescribed dose of this medicine, contact your doctor or a poison control center immediately. Symptoms of overdose may include excessive drowsiness, dizziness, nausea, and vomiting. Treatment is supportive and may include monitoring of vital signs and liver function. Do not try to induce vomiting unless told to do so by a medical professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor, and do not change the dose or stop it on your own. Because this medicine can cause drowsiness or dizziness, avoid driving or operating heavy machinery until you know how it affects you. Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding, and inform them about all other medicines, supplements, and herbal products you take. Do not share this medicine with anyone else, even if they have similar symptoms. Store it in its original packaging, away from moisture and direct sunlight, and keep it out of reach of children. If you miss a dose, follow your doctor's or pharmacist's advice rather than doubling the dose. Seek immediate medical help if you develop sudden severe headache, vision changes, calf pain, chest pain, or difficulty breathing.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients should use this medicine with caution because of possible reduced liver and kidney function. Your doctor may start with a lower dose and monitor you closely for side effects such as drowsiness and dizziness.

🤰 Pregnancy Planning (TTC)

If you are trying to conceive, talk to your doctor before taking this medicine. It may be prescribed to support the luteal phase or early pregnancy, but only under medical supervision. Do not start or stop this medicine on your own if you are planning pregnancy.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery depending on the type of procedure and your risk of blood clots. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. There are no major interactions with common dental anesthetics, but your dentist should be aware of your medicine list.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to support hormonal balance.
🥗
Eat a balanced diet rich in fruits, vegetables, and whole grains.
😴
Stay physically active with moderate exercise as advised by your doctor.
💧
Get adequate sleep and manage stress through relaxation techniques.
🧘
Avoid smoking and limit alcohol intake.
🌞
Keep track of your menstrual cycle and any symptoms to discuss with your doctor.

🏋️ Exercise Considerations

This medicine can cause drowsiness and dizziness. Avoid strenuous exercise or activities that require full alertness until you know how the medicine affects you. If you feel dizzy, stop and rest.

🥗 Diet Recommendations

Take the tablet with a meal to improve absorption.
Include fiber-rich foods to help with bloating.
Limit grapefruit and grapefruit juice.
Stay well hydrated throughout the day.
Reduce salt intake if you experience fluid retention.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. It is best to avoid these activities until you know how the medicine affects you. If your work involves shift work or heavy machinery, discuss with your doctor about timing your dose to minimize impact.

🛑 When to Stop This Medicine

Do not stop taking this medicine unless your doctor tells you to. If you experience serious side effects such as blood clots, severe allergic reactions, or liver problems, seek immediate medical attention and follow your doctor's advice about stopping. Your doctor will guide you on how to stop safely if needed.

📅 Long-Term Use Effects

Long-term use of this medicine should be monitored by your doctor. Regular check-ups may include liver function tests and assessment of your symptoms. Prolonged use may increase the risk of certain side effects such as blood clots in susceptible individuals. Your doctor will decide how long you need to take it and whether any dose adjustments are needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle and dietary changes

A healthy diet, regular exercise, and stress management can support hormonal balance.

Evidence: Well-established
Other progestogens

Dydrogesterone or other progestogens may be alternatives depending on the condition.

Evidence: Established
Non-hormonal treatments

For some conditions, non-hormonal options may be considered by your doctor.

Evidence: Varies by condition

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive routine vaccinations as advised by your doctor. If you are pregnant, discuss vaccination timing with your healthcare provider.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage if possible, and store it at room temperature away from direct sunlight and moisture. If you are crossing time zones, ask your doctor how to adjust your dosing schedule. Check the customs rules of your destination country for prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman undergoing IVF treatment
She was prescribed this medicine for luteal support after embryo transfer. She took it regularly with food as advised and reported mild drowsiness in the first week, which settled after she switched to taking it at bedtime. Her pregnancy test was positive, and she continued the medicine under her doctor's supervision.
💡 Lesson: Taking the medicine at bedtime can help manage drowsiness, and consistency is important for the best chance of success.
👤 A 28-year-old woman with irregular periods
She had irregular menstrual cycles for over a year. Her doctor prescribed this medicine for a few months. Her cycles became more regular, and she noticed less bloating after taking it with meals. She was advised not to stop the medicine on her own and to keep her follow-up appointments.
💡 Lesson: This medicine can help regulate periods, but it should be taken exactly as prescribed and reviewed regularly by a doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The time to work depends on the condition. For menstrual regulation, it may take a few weeks. For luteal support, it works during the treatment cycle. Your doctor will monitor your response.

Q: Can I take this medicine without food?

A: It is best to take this medicine with food because food improves absorption and reduces stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Can I stop taking this medicine on my own?

A: No, do not stop taking this medicine without talking to your doctor first. Stopping suddenly may cause problems.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver function?
  • Can I drive after taking this medicine?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during breastfeeding?

🔄 Substitutes for v-gest soft gelatin capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a contraceptive pill.
    Fact: This medicine is not a contraceptive. It is used for hormonal support and regulation, not for preventing pregnancy.
  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription medicine and should only be taken under a doctor's supervision.
  • Myth: This medicine causes weight gain in everyone.
    Fact: Some people may experience mild fluid retention or bloating, but not everyone gains weight.

🔄 Alternative Options

Generic Alternatives

  • Progesterone 200 mg tablet

Brand Alternatives

  • e-gest 200mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredient":"Progesterone 200 mg","route":"Oral","common_use":"Luteal support, menstrual regulation"},{"medicine":"Dydrogesterone","active_ingredient":"Dydrogesterone","route":"Oral","common_use":"Menstrual disorders, luteal support"}]

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