Depnuf 60mg Capsule (Fluoxetine): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- New or worsening thoughts of suicide or self-harm.
- Agitation, hallucinations, rapid heart rate, fever, or muscle stiffness (signs of serotonin syndrome).
- Severe allergic reaction: rash, itching, swelling of the face, lips, or throat, difficulty breathing.
- Unusual bleeding or bruising.
- Seizures or convulsions.
- Yellowing of the skin or eyes (jaundice).
- Confusion, weakness, or seizures (signs of low sodium).
If experiencing severe symptoms, call emergency services immediately.
What is uxetine 60mg capsule used for?
This medicine is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, obsessive-compulsive disorder, bulimia nervosa, and panic disorder. It works by increasing serotonin levels in the brain. The usual adult dose is 20-60 mg per day, taken orally. It may take several weeks to show full effects. Common side effects include nausea, headache, and insomnia. It carries a boxed warning for increased suicidal thoughts in young people.
- Generic Name: Fluoxetine (60mg)
- Manufacturer: Psychocare Health Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 uxetine 60mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लुओक्सेटीन 60 मिलीग्राम कैप्सूल है, जिसका उपयोग अवसाद (डिप्रेशन), ऑब्सेसिव-कंपल्सिव डिसऑर्डर (ओसीडी), बुलिमिया नर्वोसा और पैनिक डिसऑर्डर के इलाज के लिए किया जाता है। यह दवा मस्तिष्क में सेरोटोनिन नामक रसायन के स्तर को बढ़ाकर मूड को बेहतर बनाने में मदद करती है। यह दवा अकेले या थेरेपी के साथ ली जा सकती है। इसका असर दिखने में कुछ हफ्ते लग सकते हैं, इसलिए इसे नियमित रूप से लेना जरूरी है। इसे डॉक्टर के बताए अनुसार ही लें और अचानक बंद न करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मतली, सिरदर्द, अनिद्रा, उनींदापन, चिंता और दस्त शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ हफ्तों में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें सेरोटोनिन सिंड्रोम, एलर्जी प्रतिक्रिया, आत्म-नुकसान के विचार और असामान्य रक्तस्राव शामिल हो सकते हैं। यदि आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, खासकर यदि आपको लीवर, किडनी या हृदय की समस्या है। गर्भावस्था या स्तनपान के दौरान इस दवा का उपयोग करने से पहले डॉक्टर से सलाह लें। इस दवा के साथ शराब न पिएं। यह दवा नींद या चक्कर का कारण बन सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें जब तक कि आपको इसका असर पता न चल जाए। इस दवा को अचानक बंद न करें, क्योंकि इससे withdrawal के लक्षण हो सकते हैं। इसे कमरे के तापमान पर सूखी जगह पर रखें।
💊 uxetine 60mg capsule Uses & Benefits
[{"condition":"Major Depressive Disorder","description":"This medicine is used to treat major depressive disorder by helping to restore the balance of serotonin in the brain, which can improve mood, sleep, and energy levels.","evidence":"Well-established"},{"condition":"Obsessive-Compulsive Disorder","description":"This medicine is effective in reducing the frequency and intensity of obsessive thoughts and compulsive behaviors in both adults and children.","evidence":"Well-established"},{"condition":"Bulimia Nervosa","description":"This medicine is approved for the treatment of bulimia nervosa, helping to reduce binge-eating and purging behaviors.","evidence":"Well-established"},{"condition":"Panic Disorder","description":"This medicine is used to reduce the frequency and severity of panic attacks and to alleviate anticipatory anxiety.","evidence":"Well-established"},{"condition":"Premenstrual Dysphoric Disorder","description":"This medicine may be prescribed to relieve mood swings, irritability, and other symptoms associated with premenstrual dysphoric disorder.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Bipolar Depression","description":"Sometimes prescribed off-label for depressive episodes in bipolar disorder, usually in combination with a mood stabilizer.","evidence":"Limited"},{"condition":"Post-Traumatic Stress Disorder","description":"May be used off-label to help manage symptoms of PTSD, although evidence is mixed.","evidence":"Limited"},{"condition":"Social Anxiety Disorder","description":"Occasionally prescribed off-label for social anxiety disorder, though other SSRIs are more commonly used.","evidence":"Limited"}]
Primary treatment for: Major Depressive Disorder
Also treats: Obsessive-Compulsive Disorder, Bulimia Nervosa, Panic Disorder, Premenstrual Dysphoric Disorder
📋 Drug Information
| Generic Name(s) | Fluoxetine (60mg) |
| Brand Name | uxetine 60mg capsule |
| Manufacturer | Psychocare Health Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Selective Seretonin Reuptake inhibitors (SSRIs) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Keep the capsule in its original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends selective serotonin reuptake inhibitors, including fluoxetine, as first-line treatment for moderate to severe depressive disorder in adults. For children and adolescents, fluoxetine is recommended as a first-line option for moderate to severe depressive disorder, but with close monitoring for suicidal ideation. |
| ICMR Guideline | The Indian Council of Medical Research recommends fluoxetine as a first-line antidepressant for major depressive disorder. It is also recommended for obsessive-compulsive disorder and bulimia nervosa. Regular monitoring for side effects and suicidal ideation is advised, especially in young adults. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the reuptake of serotonin, a neurotransmitter, into presynaptic neurons. By blocking the serotonin transporter, it increases the concentration of serotonin in the synaptic cleft, which enhances serotonergic neurotransmission. This increased serotonin activity is thought to underlie its therapeutic effects in depression, anxiety, and other conditions. Unlike some other antidepressants, this medicine has minimal effects on norepinephrine and dopamine reuptake, which contributes to its relatively favorable side effect profile.
Mechanism Steps
💡 How to Take uxetine 60mg capsule
Strength: Capsule, 60 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for major depressive disorder is 20 mg per day, which may be increased gradually up to 60 mg per day if needed. For obsessive-compulsive disorder, the recommended starting dose is 20 mg per day, with a maximum of 60 mg per day. For bulimia nervosa, the recommended dose is 60 mg per day. For panic disorder, the starting dose is 10 mg per day, which may be increased to 60 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. This medicine is usually taken once daily in the morning, but may be taken twice daily for doses above 20 mg. Always follow your doctor's instructions. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. A lower starting dose (e.g., 10 mg per day) may be considered, and the dose should be increased cautiously. Close monitoring for side effects such as hyponatremia and falls is recommended. |
| Renal Impairment | For patients with mild to moderate renal impairment, no dose adjustment is typically necessary. For severe renal impairment (creatinine clearance <10 mL/min), a lower dose or less frequent dosing may be required. Consult your doctor. |
| Hepatic Impairment | In patients with hepatic impairment, the elimination half-life of this medicine is prolonged. A lower dose or less frequent dosing is recommended. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 80 mg, but doses above 60 mg have not been shown to be more effective and may increase the risk of side effects. The usual maximum is 60 mg per day for most indications. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of uxetine 60mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Thioridazine | Major | |
| Pimozide | Major | |
| Warfarin | Major | |
| Tramadol | Major | |
| Triptans | Moderate | |
| NSAIDs | Moderate | |
| TCAs | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Monoamine Oxidase Inhibitors (MAOIs)
- Thioridazine
- Pimozide
- Warfarin
- Other Serotonergic Drugs (e.g., triptans, tramadol, linezolid)
⚡ Moderate Interactions
- Tricyclic Antidepressants (TCAs)
- Anticoagulants (e.g., heparin, clopidogrel)
- Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
- CYP2D6 Inhibitors (e.g., quinidine, fluoxetine itself)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair your ability to think and react quickly. It may also worsen depression and anxiety symptoms.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Concomitant use with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing an MAOI.","Concomitant use with thioridazine or pimozide.","Known hypersensitivity to fluoxetine or any component of the formulation.","Should not be used in patients with severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults, especially during the first few weeks of treatment. Monitor closely.","Serotonin syndrome: potentially life-threatening. Avoid concomitant use with other serotonergic drugs.","Severe allergic reactions: discontinue and seek immediate medical attention if rash, swelling, or difficulty breathing occurs.","Abnormal bleeding: may increase risk of bleeding, especially when used with NSAIDs, aspirin, or anticoagulants.","Hyponatremia: may occur, especially in elderly patients. Monitor sodium levels.","Angle-closure glaucoma: may precipitate an acute attack. Use with caution in patients with narrow anterior chamber angles.","Mania/hypomania: may trigger a manic episode in patients with bipolar disorder. Screen for bipolar disorder before starting treatment.","Seizures: use with caution in patients with a history of seizures.","Withdrawal symptoms: do not stop abruptly. Taper gradually under medical supervision."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause nausea, vomiting, agitation, tremors, seizures, and cardiac arrhythmias. In severe cases, serotonin syndrome and coma may occur. There is no specific antidote. Treatment is supportive and symptomatic, including gastric lavage if within 1-2 hours of ingestion, activated charcoal, and management of seizures and arrhythmias. Contact a poison control center or emergency services immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose.
Additional Safety Advice
Before starting this medicine, inform your doctor about all your medical conditions, especially if you have liver disease, kidney disease, heart problems, seizures, or a history of bleeding disorders. Also, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as this medicine may affect your baby. Do not drink alcohol while taking this medicine, as it can increase drowsiness and impair your ability to think clearly. This medicine may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Do not stop taking this medicine suddenly, as this can cause withdrawal symptoms such as nausea, headache, and irritability. Your doctor will gradually reduce your dose when it is time to stop. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once. Always follow your doctor's instructions and attend regular follow-up appointments to monitor your progress.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially hyponatremia (low sodium), falls, and bleeding. A lower starting dose is recommended, and regular monitoring is advised. Use with caution in patients with cardiac disease or those taking multiple medications.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor the risks and benefits of continuing this medicine. Untreated depression can also harm both mother and baby. Your doctor may adjust your dose or switch to a different medicine. Do not stop the medicine without medical advice.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents and increase the risk of bleeding. Your doctor may advise you to temporarily stop the medicine before surgery, but do not do so without medical guidance.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may increase the risk of bleeding during dental procedures. Your dentist may take extra precautions. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or drowsiness, especially when you first start taking it. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, dizziness, or difficulty concentrating, especially during the first few weeks. Avoid driving or operating heavy machinery until you know how it affects you. It is important to inform your employer about your condition if it affects your work performance, and discuss any necessary accommodations.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will determine when it is appropriate to stop based on your response to treatment and the risk of relapse. If you need to stop, the dose should be tapered gradually over several weeks to avoid withdrawal symptoms. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe for many patients, but it may be associated with an increased risk of bone fractures, sexual dysfunction, and weight changes. Regular monitoring by your doctor is important to assess the continued need for the medicine and to manage any side effects. Some patients may require long-term maintenance therapy to prevent relapse of depression or OCD. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A type of talk therapy that can be as effective as medication for mild to moderate depression and anxiety.
Evidence: Well-establishedPhysical activity can help reduce symptoms of depression and anxiety.
Evidence: Well-establishedPractices that can help manage stress and improve mood.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures. If you are crossing time zones, adjust your dosing schedule gradually to maintain consistent blood levels; consult your doctor for specific advice. Store the medicine at room temperature and avoid leaving it in hot cars or direct sunlight. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may start to improve sleep, appetite, and energy within 1-2 weeks, but full antidepressant effects usually take 4-8 weeks. It is important to continue taking it as prescribed.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, you should not stop this medicine suddenly as it can cause withdrawal symptoms such as nausea, headache, and irritability. Your doctor will gradually reduce the dose.
A: This medicine is Pregnancy Category C. It should be used during pregnancy only if the potential benefit justifies the potential risk. Consult your doctor if you are pregnant or planning to become pregnant.
A: It is best to avoid alcohol while taking this medicine as it can increase drowsiness and worsen your condition.
🤔 Common Patient Concerns
🔄 Substitutes for uxetine 60mg capsule
View AllAlternative brands with exact same active ingredient:
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flox 60mg capsuleVGR Bio Lab ₹32.95 55.5% CHEAPER
-
Fluchem 60mg TabletChemo Biological ₹54.38 26.6% CHEAPER
-
flutine 60mg capsuleReliance Formulation Pvt Ltd ₹56.25 24% CHEAPER
-
Flutrac 60mg CapsuleMinova Life Sciences Pvt Ltd ₹60.94 17.7% CHEAPER
-
flutop 60mg tabletCrescent Therapeutics Ltd ₹62.81 15.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a 'happy pill' that instantly cures depression.
Fact: This medicine is not a cure and does not work instantly. It takes several weeks to show full effects and is most effective when combined with therapy and lifestyle changes. - Myth: This medicine is addictive and causes dependence.
Fact: This medicine is not considered addictive in the traditional sense, but it can cause withdrawal symptoms if stopped suddenly. It should be tapered gradually under medical supervision. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You should never stop this medicine without consulting your doctor. Stopping suddenly can cause withdrawal symptoms and a relapse of your condition. - Myth: This medicine causes weight gain in everyone.
Fact: Weight changes can occur, but not everyone experiences weight gain. Some people may lose weight. Monitor your weight and discuss any concerns with your doctor.
🔄 Alternative Options
Generic Alternatives
- Fluoxetine 60 mg capsule
Brand Alternatives
- Prozac
- Sarafem