Theophylline 600 Mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Seizures or convulsions
- Severe nausea and vomiting
- Fast or irregular heartbeat
- Chest pain or difficulty breathing
- Swelling of face, lips, or throat
- Severe headache with visual changes
- Confusion or agitation
If experiencing severe symptoms, call emergency services immediately.
What is unicontin-e 600 tablet cr used for?
This medicine is a bronchodilator used to treat asthma and COPD. It works by relaxing airway muscles to make breathing easier. It is not for sudden attacks and requires regular monitoring.
- Generic Name: Theophylline (600mg)
- Manufacturer: Modi Mundi Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 unicontin-e 600 tablet cr के बारे में (Hindi Summary)
उपयोग: यह दवा थियोफिलिन 600 मिलीग्राम की एक ओरल टैबलेट है, जिसका उपयोग अस्थमा और क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज (सीओपीडी) जैसी सांस की बीमारियों के इलाज में किया जाता है। यह फेफड़ों की मांसपेशियों को आराम देकर सांस लेने में आसानी करती है। यह दवा तुरंत राहत के लिए नहीं है, बल्कि नियमित रूप से लेने पर फायदा करती है। इसे डॉक्टर की सलाह के बिना शुरू या बंद न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, सिरदर्द, बेचैनी और नींद न आना शामिल हैं। गंभीर दुष्प्रभावों में तेज़ धड़कन, दौरे और गंभीर एलर्जी प्रतिक्रिया हो सकती है। अगर आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। टैबलेट को चबाएं या तोड़ें नहीं। इसे पानी के साथ निगलें। शराब और कैफीन का सेवन कम करें। अगर आपको दिल, जिगर या थायरॉइड की बीमारी है तो डॉक्टर को बताएं। अचानक सांस फूलने पर इस दवा का इस्तेमाल न करें, बल्कि अपने रेस्क्यू इनहेलर का उपयोग करें। नियमित रक्त जांच कराते रहें।
💊 unicontin-e 600 tablet cr Uses & Benefits
[{"condition":"Asthma","description":"Used as an add-on therapy for persistent asthma when inhaled corticosteroids and bronchodilators are not enough.","evidence":"Well-established"},{"condition":"Chronic Obstructive Pulmonary Disease (COPD)","description":"Helps relieve bronchospasm and improve breathing in some patients with COPD.","evidence":"Established"},{"condition":"Apnea of prematurity","description":"Sometimes used in premature infants to stimulate breathing, but this is a specialist use.","evidence":"Established in neonatal care"}]
Off-label uses: [{"condition":"Bronchitis","description":"Occasionally prescribed to relieve bronchospasm in acute or chronic bronchitis, though not a primary treatment.","evidence":"Limited"}]
Primary treatment for: Asthma
Also treats: Chronic Obstructive Pulmonary Disease (COPD), Apnea of prematurity
📋 Drug Information
| Generic Name(s) | Theophylline (600mg) |
| Brand Name | unicontin-e 600 tablet cr |
| Manufacturer | Modi Mundi Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Theophylline & its derivatives |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Theophylline is included in WHO essential medicines list for asthma and COPD management, but as a second-line agent. |
| ICMR Guideline | ICMR guidelines recommend theophylline as an add-on therapy for asthma and COPD when other treatments are insufficient. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Theophylline works by inhibiting phosphodiesterase enzymes, which leads to increased levels of cyclic AMP in airway smooth muscle cells. This causes relaxation of the bronchial muscles and widening of the airways. It also blocks adenosine receptors, which contributes to bronchodilation and stimulates the respiratory center in the brain. Additionally, it improves diaphragm contractility and mucociliary clearance.
Mechanism Steps
💡 How to Take unicontin-e 600 tablet cr
Strength: Immediate-release tablet, 600 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is individualized based on serum theophylline levels and clinical response. A typical starting dose is 300-600 mg per day in divided doses, but the exact dose must be determined by a qualified clinician. Dose adjustments are made based on serum levels, with a target range of 10-20 mcg/mL. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require lower doses due to reduced clearance and increased sensitivity to side effects. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be needed in patients with severe renal impairment. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Dose reduction is recommended in patients with liver disease. Monitor serum levels closely. |
| Maximum Daily Dose | The maximum daily dose should not exceed 600 mg without monitoring, but individual maximums vary. Follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of unicontin-e 600 tablet cr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Erythromycin | Major | |
| Phenytoin | Major | |
| Rifampicin | Major | |
| Propranolol | Moderate | |
| Cimetidine | Moderate | |
| Oral contraceptives | Moderate | |
| Caffeine | Minor | |
| St. John's wort | Minor | |
| Charcoal-broiled food | Minor |
🚨 Major Interactions
- Ciprofloxacin
- Erythromycin
- Phenytoin
- Rifampicin
⚡ Moderate Interactions
- Beta-blockers (e.g., propranolol)
- Cimetidine
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol may increase the risk of side effects such as nausea, vomiting, and rapid heartbeat. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to theophylline or any component of the formulation","Active peptic ulcer disease","Uncontrolled seizure disorder","Serious cardiac arrhythmias","Acute porphyria"]
⚠️ Warnings & Precautions
["Narrow therapeutic index; regular monitoring of serum levels is essential.","Avoid in patients with active peptic ulcer or seizure disorders.","Use with caution in patients with heart failure, liver disease, or thyroid disorders.","Smoking and certain drugs can alter theophylline metabolism.","Do not use for acute bronchospasm; use a rescue inhaler.","Elderly patients are more sensitive to side effects.","Avoid excessive caffeine intake."]
🤱 Lactation Safety
Theophylline passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but monitor the infant for irritability or insomnia.
💊 Overdose Management
Overdose can cause severe nausea, vomiting, tachycardia, arrhythmias, seizures, and cardiac arrest. Seek emergency medical attention immediately. Treatment includes activated charcoal, supportive care, and management of seizures and arrhythmias. Hemodialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not crush or chew the tablet unless your doctor says it is okay. Swallow it whole with a glass of water. Avoid drinking alcohol while taking this medicine, as it can increase the risk of side effects. Do not consume large amounts of caffeine or chocolate, as they can worsen restlessness and heart palpitations. Inform your doctor if you have heart disease, liver disease, thyroid problems, or a history of seizures. Do not use this medicine to treat sudden breathing difficulty; use your rescue inhaler instead. Keep all follow-up appointments for blood level monitoring. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to side effects and may require lower doses. Monitor serum levels closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. Theophylline is generally considered safe but dose adjustments may be needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine. It may interact with anesthesia.
🦷 Dental Procedures
Inform your dentist about this medicine. It may cause dry mouth or interact with epinephrine used in dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise may increase heart rate; monitor for palpitations. Consult your doctor before starting a new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or restlessness; avoid driving or operating machinery until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping suddenly may worsen your condition.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of serum levels to avoid toxicity. It may cause insomnia, restlessness, and gastrointestinal upset. Periodic liver and heart function tests may be needed. Do not stop suddenly without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
First-line therapy for asthma.
Evidence: Well-establishedUsed as add-on therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions. Annual flu vaccine is recommended for patients with chronic respiratory diseases.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about dose timing. Check customs regulations for controlled substances.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes to 1 hour after taking a dose.
A: Yes, you can take it with food to reduce stomach upset, but avoid high-fat meals as they may affect absorption.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for unicontin-e 600 tablet cr
View AllAlternative brands with exact same active ingredient:
-
od phyllin 600 mg tabletSun Pharmaceutical Industries Ltd ₹10.34 97.3% CHEAPER
-
theobid 600mg tabletSun Pharmaceutical Industries Ltd ₹10.82 97.2% CHEAPER
-
Theoday 600mg TabletCipla Ltd ₹37.50 90.2% CHEAPER
-
Theoresp 600mg TabletLife Medicare & Biotech Pvt Ltd ₹55.78 85.5% CHEAPER
-
Theoresp Plus 600mg TabletLife Medicare & Biotech Pvt Ltd ₹59.49 84.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Theophylline can be used as a rescue inhaler.
Fact: Theophylline is a long-term controller medicine and is not effective for immediate relief of acute attacks. - Myth: Theophylline is safe at any dose.
Fact: Theophylline has a narrow therapeutic window and can cause serious side effects if levels are too high.
🔄 Alternative Options
Generic Alternatives
- Theophylline 600 mg immediate-release tablet
Brand Alternatives
- Od Phyllin 600 mg Tablet