uniclor 750mg tablet mr - Cefaclor (750mg) medicine

Distaclor 750mg Tablet: Complete Medicine Guide

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🏭 United Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: rash, itching, swelling of face/lips/throat, difficulty breathing.
  • Persistent diarrhea, abdominal cramps, or fever (possible C. difficile infection).
  • Blood in stool or vomit.
  • Yellowing of skin or eyes (jaundice).
  • Decreased urine output or swelling in legs (kidney problems).
  • Unusual bruising or bleeding.
  • Seizures.

If experiencing severe symptoms, call emergency services immediately.

What is uniclor 750mg tablet mr used for?

This medicine is a cephalosporin antibiotic used to treat bacterial infections of the respiratory tract, ear, throat, skin, and urinary tract. It works by killing bacteria. Take it exactly as prescribed, and complete the full course.

  • Generic Name: Cefaclor (750mg)
  • Manufacturer: United Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 uniclor 750mg tablet mr के बारे में (Hindi Summary)

उपयोग: यह दवा एक सेफलोस्पोरिन एंटीबायोटिक है जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे कि श्वसन तंत्र, कान, गले, त्वचा और मूत्र मार्ग के संक्रमण। यह बैक्टीरिया को मारकर काम करती है। इसका उपयोग केवल डॉक्टर के पर्चे पर ही करें और पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज एलर्जी, गंभीर दस्त, त्वचा पर चकत्ते और खून की समस्याएं शामिल हो सकती हैं। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी एलर्जी, गुर्दे की बीमारी, पेट की समस्या, गर्भावस्था या स्तनपान के बारे में बताएं। दवा को डॉक्टर के बताए अनुसार ही लें, भोजन के साथ या बिना भोजन के ले सकते हैं। कोर्स पूरा करें, बीच में न छोड़ें। शराब न पिएं। खुराक छूट जाने पर याद आते ही लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें। दोहरी खुराक न लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 uniclor 750mg tablet mr Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat bacterial infections of the respiratory tract, including bronchitis and pneumonia caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Otitis media","description":"Effective in treating middle ear infections caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"Used to treat throat infections caused by Streptococcus pyogenes (group A beta-hemolytic streptococci).","evidence":"Well-established"},{"condition":"Skin and skin structure infections","description":"Treats bacterial skin infections caused by susceptible organisms, including cellulitis and impetigo.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Used for uncomplicated urinary tract infections caused by susceptible bacteria like Escherichia coli and Klebsiella species.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used as an alternative for early Lyme disease in patients allergic to doxycycline, though not first-line.","evidence":"Limited"},{"condition":"Prophylaxis for dental procedures","description":"Occasionally used as prophylaxis in patients with certain heart conditions undergoing dental procedures, but not routinely recommended.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Otitis media, Pharyngitis, Tonsillitis, Skin infections, Urinary tract infections

📋 Drug Information

Generic Name(s)Cefaclor (750mg)
Brand Nameuniclor 750mg tablet mr
ManufacturerUnited Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 2nd generation
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Do not refrigerate. Keep in the original container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food if it causes stomach upset.
2
Complete the full course of treatment even if you feel better after a few days.
3
Do not share this medicine with others, even if they have similar symptoms.
4
Inform your doctor if you have kidney problems, as dose adjustment may be needed.
5
Avoid alcohol while taking this medicine to reduce the risk of side effects.
6
If you develop persistent diarrhea, consult your doctor before taking any anti-diarrheal medication.
7
Report any signs of allergic reaction, such as rash, itching, or swelling, immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Throat infection
This medicine is commonly prescribed for bacterial throat infections.
Likely Use
✅
Ear infection
This medicine is used for middle ear infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. The presence of food may delay absorption slightly but does not significantly reduce the overall extent of absorption. Peak plasma concentrations are typically achieved within 30 to 60 minutes after dosing.
DistributionThis medicine distributes widely into body tissues and fluids, including the respiratory tract, middle ear, skin, and urinary tract. It crosses the placenta and is excreted in breast milk in small amounts. Protein binding is approximately 25%.
Protein BindingApproximately 25% bound to plasma proteins.
MetabolismThis medicine is not extensively metabolized in the body. It is primarily excreted unchanged in the urine.
Half-LifeThe elimination half-life is approximately 0.6 to 0.9 hours in patients with normal kidney function. In patients with renal impairment, the half-life may be prolonged.
ExcretionThis medicine is excreted primarily unchanged in the urine via glomerular filtration and tubular secretion. About 60-85% of an oral dose is excreted in the urine within 8 hours.
BioavailabilityThe oral bioavailability of this medicine is approximately 50-60% when taken on an empty stomach, but it may be slightly reduced when taken with food.
Onset of ActionThe onset of action is typically within 1 to 2 hours after oral administration, as the drug reaches peak concentrations and begins to exert its antibacterial effect.
Peak Plasma TimePeak plasma concentrations are usually reached within 30 to 60 minutes after oral administration.
Duration of ActionThe duration of action is generally about 6 to 8 hours, which supports dosing every 8 hours. However, the exact duration depends on the susceptibility of the infecting organism and the patient's renal function.

How It Works

This medicine works by binding to specific proteins called penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final step of peptidoglycan synthesis, which is essential for the strength and rigidity of the bacterial cell wall. As a result, the cell wall becomes weak and the bacteria eventually die due to osmotic pressure. This medicine is bactericidal, meaning it kills the bacteria directly. It is effective against a range of gram-positive and gram-negative bacteria, but it is not active against methicillin-resistant Staphylococcus aureus (MRSA) or Pseudomonas aeruginosa.

Mechanism Steps

1
Binding to penicillin-binding proteins: This medicine binds to specific penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
2
Inhibition of peptidoglycan synthesis: By binding to PBPs, it inhibits the transpeptidation reaction that cross-links peptidoglycan chains, which are essential for cell wall strength.
3
Cell wall weakening and lysis: The weakened cell wall cannot withstand osmotic pressure, leading to bacterial cell lysis and death.

💡 How to Take uniclor 750mg tablet mr

Strength: 750 mg immediate-release tablet

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3If it upsets your stomach, take it with a meal or snack.
4Take at evenly spaced intervals as prescribed by your doctor.
5Complete the full course of treatment even if you feel better.
6Do not crush, chew, or break the tablet unless instructed by your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 250 mg to 500 mg every 8 hours, depending on the type and severity of the infection. For more severe infections, doses up to 750 mg every 8 hours may be prescribed. The maximum recommended daily dose is 4 grams. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on the child's age, weight, and infection.
Elderly DosageElderly patients may have reduced renal function and may require dose adjustment. Dose must be individualized by a qualified clinician based on renal function.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. For creatinine clearance 10-30 mL/min, the dose may be reduced to 250-500 mg every 12 hours. For creatinine clearance less than 10 mL/min, the dose may be reduced to 250-500 mg every 24 hours. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is recommended for hepatic impairment, but use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 4 grams (4000 mg) for adults with normal renal function.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
May take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels, though interaction not well established.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of uniclor 750mg tablet mr

✅ Common Side Effects

Diarrhea (Common (1-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent or severe.
Nausea (Common (1-10%))
Take with food to reduce nausea. Consult doctor if it persists.
Vomiting (Common (1-10%))
Take with food and avoid large meals. Consult doctor if vomiting continues.
Abdominal pain (Common (1-10%))
Take with food. If pain is severe or persistent, consult doctor.
Headache (Common (1-10%))
Usually resolves. Rest and hydration may help. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face/lips/throat, difficulty breathing, or dizziness.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you develop persistent diarrhea, abdominal cramps, or fever.
Stevens-Johnson syndrome (Very rare (<0.01%))
Seek immediate medical attention if you notice skin rash, blisters, peeling skin, or sores in mouth.
Blood dyscrasias (e.g., neutropenia, thrombocytopenia) (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection to your doctor.
Seizures (Very rare (<0.01%))
Seek immediate medical attention if seizures occur, especially in patients with renal impairment.

⚠️ Rare Side Effects

Serum sickness-like reaction
Consult doctor if you experience fever, rash, joint pain, or swelling.
Interstitial nephritis
Seek medical attention if you notice decreased urine output, swelling, or fatigue.
Hepatic dysfunction
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Gentamicin Major
Furosemide Major
Probenecid Moderate
Oral contraceptives Moderate
Antacids Minor
Iron supplements Minor

🚨 Major Interactions

  • Warfarin
  • Aminoglycosides (e.g., gentamicin)
  • Loop diuretics (e.g., furosemide)

⚡ Moderate Interactions

  • Probenecid
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach upset, dizziness, and other side effects. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cefaclor or other cephalosporin antibiotics","History of severe allergic reaction to penicillins (cross-reactivity possible)","Previous anaphylactic reaction to beta-lactam antibiotics"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be necessary.","May cause Clostridium difficile-associated diarrhea; if persistent diarrhea occurs, discontinue and consult doctor.","Serious allergic reactions, including anaphylaxis, can occur. Discontinue immediately if allergic reaction suspected.","May cause seizures in patients with renal impairment; use with caution.","Prolonged use may lead to overgrowth of non-susceptible organisms (superinfection).","Not effective against viral infections. Do not use for colds or flu.","May interfere with some laboratory tests (e.g., urine glucose tests)."]

🤱 Lactation Safety

This medicine is excreted in human breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Monitor the infant for diarrhea, thrush, or allergic reactions.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, and diarrhea. In severe cases, seizures may occur, especially in patients with renal impairment. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases. Contact a poison control center or emergency room immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you are allergic to cefaclor, other cephalosporins, or penicillins. Also, disclose any history of kidney disease, gastrointestinal problems (especially colitis), or if you are pregnant, planning to become pregnant, or breastfeeding. Take this medicine exactly as prescribed, with or without food, but taking it with food may help reduce stomach upset. Do not skip doses or stop taking it early, even if you feel better, as this can lead to antibiotic resistance. Avoid alcohol while taking this medicine, as it may increase the risk of stomach upset and other side effects. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and are more susceptible to side effects. Dose adjustment may be necessary. Monitor renal function closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is Pregnancy Category B, but use only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully. Inform your surgeon if you are taking this medicine before any surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain dental medications or affect healing. Your dentist may recommend postponing non-urgent procedures until you complete the course.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help flush out the infection.
🥗
Get plenty of rest to support your immune system.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Practice good hygiene, such as frequent handwashing, to prevent spread of infection.
🧘
Avoid close contact with others while you are contagious.
🌞
Complete the full course of antibiotics as prescribed.

🏋️ Exercise Considerations

This medicine may cause dizziness or fatigue in some people. Avoid strenuous exercise if you feel unwell. Listen to your body and rest as needed.

🥗 Diet Recommendations

Include probiotics like yogurt to help maintain healthy gut flora.
Stay hydrated with water and clear fluids.
Avoid spicy and fatty foods if you have stomach upset.
Eat small, frequent meals if you experience nausea.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid driving if you feel dizzy. Most people can continue their normal activities, but rest if needed.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to overgrowth of non-susceptible organisms, causing superinfections such as oral thrush or vaginal yeast infections. It may also increase the risk of antibiotic resistance. Prolonged use should be avoided unless prescribed for a specific indication. Regular monitoring of renal and hepatic function may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection and susceptibility, other antibiotics like amoxicillin, cefuroxime, or azithromycin may be used.

Evidence: Well-established
Symptomatic treatment

For viral infections, rest, fluids, and over-the-counter remedies may be used.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Avoid live vaccines during and shortly after antibiotic therapy. Consult your doctor for specific advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and avoid direct sunlight. If crossing time zones, adjust dosing times gradually under medical advice. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a throat infection
She was prescribed this medicine for streptococcal pharyngitis. She took it with food to avoid stomach upset and completed the 10-day course. Her symptoms improved within 3 days, but she continued the full course as advised. She experienced mild diarrhea, which resolved after finishing the antibiotic.
💡 Lesson: Completing the full course is essential to prevent recurrence and resistance, even if symptoms improve quickly.
👤 A 60-year-old man with a urinary tract infection
He had a history of kidney disease and was prescribed a lower dose of this medicine. His doctor monitored his kidney function during treatment. He recovered well without any serious side effects.
💡 Lesson: Dose adjustment is important in patients with kidney disease to prevent toxicity.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-2 days, but it may take a few days for full effect. Complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: It is Pregnancy Category B. It should be used during pregnancy only if clearly needed. Consult your doctor.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may increase the risk of stomach upset and other side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for uniclor 750mg tablet mr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not work for viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full course as prescribed, even if you feel better, to prevent recurrence and resistance.
  • Myth: Antibiotics are safe to take without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Cefaclor

Brand Alternatives

  • Distaclor 750mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cefaclor","class":"Second-generation cephalosporin","route":"Oral","common_uses":"Respiratory, ear, skin, urinary infections"},{"medicine":"Cefuroxime","class":"Second-generation cephalosporin","route":"Oral","common_uses":"Respiratory, ear, skin, urinary infections"},{"medicine":"Cefixime","class":"Third-generation cephalosporin","route":"Oral","common_uses":"Respiratory, ear, urinary infections"}]

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