ultravist 370mg i/ml injection - Iopromide (370mg I/ml) medicine

Ultravist 370mg I/ml Injection: Complete Guide To Uses, Safety, And Side Effects

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🏭 Zydus Cadila 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for diagnostic use.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or wheezing
  • Swelling of the face, lips, tongue, or throat
  • Severe rash or hives
  • Sudden drop in blood pressure or fainting
  • Chest pain or palpitations
  • Decreased urine output or swelling
  • Seizures or confusion

If experiencing severe symptoms, call emergency services immediately.

What is ultravist 370mg i/ml injection used for?

This medicine is an injectable contrast medium containing iopromide, used to enhance the visibility of internal structures during CT scans, angiography, and urography. It is administered only by healthcare professionals in a medical facility.

  • Generic Name: Iopromide (370mg I/ml)
  • Manufacturer: Zydus Cadila
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ultravist 370mg i/ml injection के बारे में (Hindi Summary)

उपयोग: यह दवा एक इंजेक्शन योग्य कंट्रास्ट माध्यम है जिसमें आयोप्रोमाइड नामक सक्रिय तत्व होता है। इसका उपयोग सीटी स्कैन, एंजियोग्राफी और यूरोग्राफी जैसी डायग्नोस्टिक इमेजिंग प्रक्रियाओं में शरीर के आंतरिक अंगों और रक्त वाहिकाओं को स्पष्ट रूप से देखने के लिए किया जाता है। यह दवा किसी बीमारी का इलाज नहीं करती बल्कि डॉक्टर को सही निदान करने में मदद करती है। इसे केवल अस्पताल या क्लिनिक में प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही इंजेक्शन के रूप में दिया जाता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर गर्माहट या दर्द, मुँह में धातु जैसा स्वाद, मतली, उल्टी, सिरदर्द और चक्कर आना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में अपने आप ठीक हो जाते हैं। कभी-कभी त्वचा पर चकत्ते, खुजली या सूजन हो सकती है। गंभीर प्रतिक्रियाएँ दुर्लभ हैं लेकिन इनमें साँस लेने में कठिनाई, रक्तचाप में गिरावट और गुर्दे की समस्या शामिल हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल अस्पताल में प्रशिक्षित डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। इससे पहले कि आपको यह इंजेक्शन दिया जाए, अपने डॉक्टर को अपनी सभी बीमारियों, खासकर गुर्दे की बीमारी, मधुमेह, थायरॉइड विकार, अस्थमा, एलर्जी और हृदय रोग के बारे में बताएं। अपनी सभी दवाओं की जानकारी भी दें। प्रक्रिया से पहले और बाद में पर्याप्त पानी पिएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। प्रक्रिया के बाद अस्वस्थ महसूस होने पर वाहन न चलाएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 ultravist 370mg i/ml injection Uses & Benefits

[{"condition":"Contrast-enhanced computed tomography (CT)","description":"This medicine is used to improve the visibility of blood vessels, organs, and lesions during CT scans of the head, neck, chest, abdomen, and pelvis.","evidence":"Well-established"},{"condition":"Angiography and interventional radiology","description":"It is injected into blood vessels to visualise arterial and venous anatomy during diagnostic and interventional procedures.","evidence":"Well-established"},{"condition":"Urography","description":"This medicine is used for intravenous urography to evaluate the urinary tract and kidney function.","evidence":"Well-established"},{"condition":"Digital subtraction angiography (DSA)","description":"It enhances the contrast between vessels and surrounding tissues in DSA studies.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Not established from the available information.","description":"Off-label uses for this medicine are not established from the available information.","evidence":"Not established from the available information."}]

Primary treatment for: Diagnostic imaging (contrast enhancement)

Also treats: Vascular diseases, Tumours, Infections, Trauma

📋 Drug Information

Generic Name(s)Iopromide (370mg I/ml)
Brand Nameultravist 370mg i/ml injection
ManufacturerZydus Cadila
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOTHERS
Action ClassX ray contrast media (Diagnostic agents)
Route of AdministrationParenteral (intravascular injection)
StorageStore below 30°C. Protect from light and freezing. Keep the container in the outer carton to protect from light. Do not use if the solution is discoloured or contains particulate matter.
Shelf LifeRefer to the product label for the exact shelf life. Typically 2 to 3 years from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always assess renal function before administering this medicine, especially in patients with diabetes or hypertension.
2
Ensure adequate hydration before and after the procedure to reduce the risk of contrast-induced nephropathy.
3
Ask about previous reactions to contrast media and keep resuscitation equipment ready.
4
Temporarily discontinue metformin before the procedure and restart after 48 hours once renal function is stable.
5
Use the lowest effective volume of contrast medium to minimise risks.
6
Monitor patients for at least 30 minutes after injection for any immediate reactions.
7
Document any adverse reaction clearly in the patient's records.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Need for contrast-enhanced imaging
This medicine is used for diagnostic imaging.
Likely Use
❌
Fever
This medicine is not a treatment for fever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered by injection, so absorption from the gastrointestinal tract is not applicable. After intravascular injection, it is completely bioavailable within the vascular space.
DistributionAfter injection, iopromide distributes rapidly into the intravascular and extracellular fluid compartments. It does not cross the intact blood-brain barrier to a significant extent. In patients with normal renal function, the volume of distribution is approximately 0.2 to 0.3 litres per kilogram. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingIopromide has a low plasma protein binding of approximately 1 to 2 percent.
MetabolismIopromide is not metabolised in the body. It is excreted unchanged.
Half-LifeThe elimination half-life of iopromide in patients with normal renal function is approximately 2 hours. In patients with renal impairment, the half-life is prolonged.
ExcretionThis medicine is excreted almost entirely unchanged by the kidneys through glomerular filtration. Approximately 90 percent of the administered dose is recovered in the urine within 24 hours in patients with normal renal function.
BioavailabilityNot applicable. This medicine is given by injection, so it is completely bioavailable in the vascular space.
Onset of ActionThe contrast effect is immediate after injection and is visible on imaging as soon as the agent reaches the area of interest.
Peak Plasma TimePeak plasma concentration occurs immediately after the end of the injection.
Duration of ActionThe contrast enhancement lasts for a few minutes to several minutes, depending on the imaging procedure and the patient's circulation and renal function.

How It Works

Iopromide is a non-ionic, monomeric, low-osmolar iodinated contrast agent. After intravascular injection, it distributes within the vascular space and extracellular fluid. The iodine atoms in the molecule absorb X-rays, increasing the attenuation of the X-ray beam and thereby enhancing the contrast between different tissues and structures on the resulting images. This medicine does not exert any pharmacological therapeutic effect; its action is purely physical and diagnostic.

Mechanism Steps

1
Intravascular injection: This medicine is injected into a vein or artery by a healthcare professional.
2
Distribution in vascular and extracellular spaces: Iopromide mixes with blood and distributes throughout the vascular system and extracellular fluid.
3
X-ray attenuation: The iodine atoms absorb X-rays, reducing the number of X-ray photons that reach the detector.
4
Image contrast enhancement: The differential attenuation between iodine-containing and non-containing tissues creates contrast on the images.
5
Renal excretion: Iopromide is eliminated unchanged by the kidneys through glomerular filtration.

💡 How to Take ultravist 370mg i/ml injection

Strength: Iopromide 370 mg I/mL solution for injection

1This medicine is given by a healthcare professional in a medical facility.
2You will be asked to lie down for the injection.
3The injection site will be cleaned and a needle or catheter inserted.
4The contrast medium is injected over a few seconds to minutes.
5You may feel a warm sensation or metallic taste during the injection.
6After the procedure, you will be monitored for a short period.
7Drink plenty of water after the procedure unless advised otherwise.

Dosage Information

Adult DosageThe dose of this medicine depends on the type of examination, the body region, the patient's weight, and renal function. For contrast-enhanced CT, typical volumes range from 50 to 150 mL of the 370 mg I/mL solution, administered intravenously. For angiography, the volume and concentration depend on the specific procedure. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and are at higher risk of contrast-induced nephropathy. The dose should be carefully adjusted based on renal function, and adequate hydration should be ensured.
Renal ImpairmentIn patients with renal impairment, the dose should be minimized, and adequate hydration should be ensured. The risk of contrast-induced nephropathy is increased. Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentNo specific dose adjustment is required for hepatic impairment, as iopromide is not metabolised by the liver. However, caution is advised in patients with combined hepatic and renal impairment.
Maximum Daily DoseThe maximum dose is determined by the clinician based on the procedure and patient factors. There is no fixed maximum daily dose; it must be individualized.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Not applicable
Not applicable
This medicine is given by injection in a medical setting.

⏰ What to Do If You Miss a Dose

📌 Not applicable
→ This medicine is given as a single dose in a medical facility.
💡 No missed dose instructions apply.

⚠️ Side Effects of ultravist 370mg i/ml injection

✅ Common Side Effects

Warmth or pain at injection site (Common (5-10%))
This usually resolves spontaneously within minutes. Inform the medical staff if it is severe.
Metallic taste in the mouth (Common (5-10%))
This is transient and requires no treatment.
Nausea (Common (5-10%))
Inform the staff. It usually settles without medication.
Headache (Common (5-10%))
Rest and hydration usually help. Consult a doctor if it persists.
Dizziness (Common (5-10%))
Lie down and inform the staff. Avoid driving until it resolves.

🚨 Serious Side Effects

Anaphylactoid reaction (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, or throat, difficulty breathing, or a widespread rash.
Contrast-induced nephropathy (Uncommon (0.1-1%))
Report decreased urine output or swelling. Your doctor will monitor kidney function.
Severe hypotension (Rare (<0.1%))
This is managed by the medical team during the procedure.
Thyroid storm (Very rare (<0.01%))
Seek medical attention if you develop rapid heartbeat, fever, or agitation after the procedure.

⚠️ Rare Side Effects

Laryngeal oedema
Emergency medical treatment is required.
Cardiac arrest
Immediate resuscitation is required.
Seizures
Seek immediate medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Metformin Major
Nephrotoxic drugs Major
Beta-blockers Major
Diuretics Moderate
NSAIDs Moderate
Interleukin-2 Moderate

🚨 Major Interactions

  • Metformin
  • Nephrotoxic drugs (e.g., aminoglycosides, amphotericin B, cisplatin)
  • Beta-blockers

⚡ Moderate Interactions

  • Diuretics
  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Interleukin-2

🍷 Alcohol Interaction

Alcohol may worsen dehydration and increase the risk of kidney problems. Patients should avoid alcohol before and after the procedure until they are fully recovered.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to iopromide or other iodinated contrast agents","Manifest hyperthyroidism","Severe renal impairment without careful risk-benefit assessment","Pregnancy, unless the benefit clearly outweighs the risk"]

⚠️ Warnings & Precautions

["This medicine must only be administered by trained healthcare professionals in a facility equipped to handle contrast reactions.","Ensure adequate hydration before and after the procedure.","Use with caution in patients with a history of allergy, asthma, or previous contrast reactions.","Use with caution in patients with renal impairment, diabetes, or heart disease.","Metformin should be temporarily discontinued before the procedure.","Inform your doctor if you are pregnant or breastfeeding.","Delayed reactions may occur; report any symptoms to your doctor."]

🤱 Lactation Safety

Iopromide is excreted in human breast milk in small amounts. The amount ingested by the infant is likely to be very small. However, as a precaution, some guidelines suggest that breastfeeding may be interrupted for 24 hours after the administration of this medicine. Consult your doctor for personalised advice.

💊 Overdose Management

Overdose with this medicine is unlikely because it is administered by healthcare professionals in a controlled setting. In case of accidental overdose, treatment is symptomatic and supportive. Renal function should be monitored, and hydration should be maintained. There is no specific antidote.

⏰ Missed Dose

Not applicable. This medicine is given as a single dose in a medical facility under professional supervision.

Additional Safety Advice

General Safety

This medicine must only be administered by a qualified healthcare professional in a medical facility with resuscitation equipment. Before the injection, inform your doctor about all your medical conditions, especially kidney problems, diabetes, thyroid disorders, asthma, allergies, or heart disease. Also disclose all medicines you are taking, including metformin, beta-blockers, diuretics, and non-steroidal anti-inflammatory drugs. Adequate hydration before and after the procedure helps protect your kidneys. If you are pregnant or think you might be pregnant, tell your doctor, because the necessity of the examination must be carefully evaluated. If you are breastfeeding, discuss with your doctor whether to pause breastfeeding for a short period after the injection. Do not drive or operate heavy machinery immediately after the procedure if you feel unwell. Report any delayed symptoms such as skin rash, swelling, or difficulty breathing to your doctor without delay.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of contrast-induced nephropathy and cardiovascular reactions. Renal function should be assessed, and adequate hydration ensured. The dose should be minimised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, inform your doctor before the procedure. The necessity of the examination should be carefully evaluated. Use effective contraception if there is a possibility of pregnancy.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your doctor. The risk of contrast-induced nephropathy may be higher. Adequate hydration is important.

🦷 Dental Procedures

There are no specific considerations for dental procedures. However, inform your dentist about any recent contrast administration.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated before and after the procedure.
🥗
Inform your doctor about all your medications and allergies.
😴
Follow your doctor's advice regarding temporary discontinuation of metformin.
💧
Avoid alcohol before and after the procedure.
🧘
Report any delayed symptoms promptly.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after the procedure. Rest and hydrate well. You can resume normal activities once you feel fully recovered.

🥗 Diet Recommendations

Drink plenty of water before and after the procedure.
Avoid alcohol for 24 hours after the procedure.
Eat a light meal after the procedure if you feel well.

💼 Impact on Daily Work & Life

You may need to take a few hours off work for the procedure and recovery. Avoid driving or operating machinery if you feel dizzy or unwell. Most people can resume normal activities the same day.

🛑 When to Stop This Medicine

This medicine is given as a single dose; there is no question of stopping it. If you experience any adverse effects, inform your doctor immediately.

📅 Long-Term Use Effects

This medicine is used as a single dose for diagnostic purposes and is not intended for long-term use. There are no known long-term effects from a single administration. However, repeated contrast procedures may increase the cumulative risk of kidney injury. Monitoring of renal function is advised in patients with risk factors.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Non-contrast imaging

In some cases, imaging without contrast may be sufficient.

Evidence: Well-established
Alternative contrast agents

Other contrast agents such as iohexol or iodixanol may be used.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, inform your doctor about recent vaccinations.

📦 Storage Guide

✅ DO

Store below 30°C

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✈️ Traveling with This Medicine

This medicine is administered in a medical facility and is not for self-administration during travel. If you are scheduled for a contrast-enhanced procedure while travelling, carry a copy of your prescription and medical records. Inform the healthcare provider about your travel plans and any recent contrast procedures. Ensure you are well hydrated before and after the procedure. If you have any delayed symptoms, seek medical attention locally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of kidney disease
He was scheduled for a contrast-enhanced CT scan. His doctor checked his kidney function, ensured he was well hydrated, and used a minimal volume of this medicine. The scan was successful, and his kidney function remained stable after the procedure.
💡 Lesson: Proper assessment and hydration are crucial to prevent kidney complications in at-risk patients.
👤 A 40-year-old woman with a known allergy to shellfish
She informed the doctor about her allergy before the procedure. The medical team took extra precautions and premedicated her with antihistamines and steroids. She experienced only mild itching, which was easily managed.
💡 Lesson: Always disclose your allergies to the medical team before receiving contrast media.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The contrast effect is immediate after injection and lasts for a few minutes.

Q: Will I feel anything during the injection?

A: You may feel a warm sensation or a metallic taste, which is normal and transient.

Q: Can I drive after the procedure?

A: It is advisable to avoid driving immediately after the procedure if you feel unwell.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine if I have kidney disease?
  • Will this medicine affect my thyroid?
  • Can I breastfeed after receiving this medicine?
  • What should I do if I have an allergic reaction?
  • How long does the contrast effect last?
  • Is this medicine safe for diabetics?

🛑 Myths vs. Facts

  • Myth: This medicine is a treatment for diseases.
    Fact: This medicine is a diagnostic contrast agent and does not treat any disease.
  • Myth: This medicine can be taken at home.
    Fact: This medicine must only be administered by a healthcare professional in a medical facility.

🔄 Alternative Options

Generic Alternatives

  • Iopromide injection

Brand Alternatives

  • Ultravist 370mg I/ml injection

📊 Comparison with Similar Medicines

[{"medicine":"Iopromide","class":"Non-ionic monomeric","osmolarity":"Low","iodine_concentration":"370 mg I/mL","use":"CT, angiography, urography"},{"medicine":"Iohexol","class":"Non-ionic monomeric","osmolarity":"Low","iodine_concentration":"Varies","use":"CT, angiography, urography"},{"medicine":"Iodixanol","class":"Non-ionic dimeric","osmolarity":"Iso-osmolar","iodine_concentration":"Varies","use":"CT, angiography, urography"}]

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