U Tryp 100000IU Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe allergic reaction with drop in blood pressure
- Unusual bleeding or bruising
- Decreased urine output
- Yellowing of skin or eyes
- Severe abdominal pain or vomiting blood
- Chest pain or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is uliject 100000iu injection used for?
This medicine is a protease inhibitor injection used in hospitals to treat acute pancreatitis, severe sepsis, and post-surgical inflammation by reducing excessive inflammation and protecting organs.
- Generic Name: Ulinastatin (100000IU)
- Manufacturer: Flagship Biotech International
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 uliject 100000iu injection के बारे में (Hindi Summary)
उपयोग: यह दवा एक इंजेक्शन है जिसमें यूलिनास्टैटिन नामक सक्रिय तत्व होता है। इसका उपयोग अस्पताल में गंभीर सूजन और ऊतक क्षति को नियंत्रित करने के लिए किया जाता है, जैसे कि तीव्र अग्नाशयशोथ (पैन्क्रियाटाइटिस), गंभीर सेप्सिस, और बड़ी सर्जरी के बाद। यह दवा शरीर में उन एंजाइमों को रोकती है जो सूजन पैदा करते हैं, जिससे अंगों की रक्षा होती है। यह दवा केवल डॉक्टर की देखरेख में ही दी जाती है और घर पर स्वयं नहीं लगाई जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द या लालिमा, मतली, उल्टी, दस्त और त्वचा पर चकत्ते शामिल हैं। कभी-कभी लीवर एंजाइम में मामूली वृद्धि या श्वेत रक्त कोशिकाओं में कमी हो सकती है। गंभीर लेकिन दुर्लभ दुष्प्रभावों में तेज एलर्जी प्रतिक्रिया, सांस लेने में कठिनाई, चेहरे या गले में सूजन, और रक्तचाप में अचानक गिरावट शामिल हैं। यदि कोई गंभीर दुष्प्रभाव दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। इसे स्वयं न लगाएं। अपने डॉक्टर को उन सभी दवाओं के बारे में बताएं जो आप ले रहे हैं, विशेष रूप से रक्त पतला करने वाली दवाएं। यदि आपको एलर्जी, रक्तस्राव विकार, गुर्दे या यकृत की बीमारी है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान यह दवा केवल विशेषज्ञ की सलाह पर ही लें। इलाज के दौरान शराब से बचें। असामान्य रक्तस्राव, चकत्ते या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर को बताएं।
💊 uliject 100000iu injection Uses & Benefits
[{"condition":"Acute pancreatitis","description":"This medicine is used to reduce inflammation and tissue damage in acute pancreatitis, helping to improve symptoms and outcomes.","evidence":"Well-established in some regions; evidence varies"},{"condition":"Severe sepsis and septic shock","description":"It is used as an adjunctive therapy to control excessive inflammatory response in severe sepsis.","evidence":"Moderate; used in some countries"},{"condition":"Post-surgical inflammation","description":"This medicine may be given after major surgery to reduce inflammation and prevent organ injury.","evidence":"Limited; used in selected cases"},{"condition":"Acute lung injury","description":"It may be used to reduce lung inflammation in conditions like acute respiratory distress syndrome.","evidence":"Limited; not universally accepted"}]
Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Sometimes used off-label to protect kidneys from contrast dye injury.","evidence":"Limited"},{"condition":"Severe burns","description":"May be used to reduce systemic inflammation in severe burn patients.","evidence":"Limited"}]
Primary treatment for: Acute pancreatitis
Also treats: Severe sepsis, Post-surgical inflammation, Acute lung injury
📋 Drug Information
| Generic Name(s) | Ulinastatin (100000IU) |
| Brand Name | uliject 100000iu injection |
| Manufacturer | Flagship Biotech International |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Protease inhibitors- Pancreatitis |
| Route of Administration | Parenteral (intravenous or intramuscular injection) |
| Storage | Store in a refrigerator (2-8°C). Do not freeze. Keep in the original container to protect from light. |
| Shelf Life | Not established from the available information. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting a broad range of proteolytic enzymes, including trypsin, chymotrypsin, plasmin, and neutrophil elastase. By blocking these enzymes, it reduces the breakdown of proteins and the activation of inflammatory pathways. This helps to stabilize cell membranes, reduce capillary leakage, and protect organs from inflammatory damage. It also suppresses the release of inflammatory cytokines and reactive oxygen species, contributing to its anti-inflammatory effects.
Mechanism Steps
💡 How to Take uliject 100000iu injection
Strength: Injection: 100000 IU
Dosage Information
| Adult Dosage | The dose of this medicine is determined by the doctor based on the condition being treated, its severity, and the patient's overall health. It is given as an intravenous or intramuscular injection, often in a hospital setting. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Dose adjustments may be needed based on kidney and liver function. Consult your doctor. |
| Renal Impairment | Dose adjustment may be required in patients with kidney disease. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Dose adjustment may be required in patients with liver disease. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | Not established from the available information. |
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of uliject 100000iu injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Heparin | Major | |
| Alteplase | Major | |
| NSAIDs | Moderate |
🚨 Major Interactions
- Anticoagulants (e.g., warfarin, heparin)
- Thrombolytic agents (e.g., alteplase)
⚡ Moderate Interactions
- NSAIDs
🍷 Alcohol Interaction
Alcohol may increase the risk of liver and stomach side effects. It is advisable to avoid alcohol while receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to ulinastatin or any component of the injection","Severe bleeding disorders","Pregnancy unless clearly needed","Breastfeeding unless advised by doctor"]
⚠️ Warnings & Precautions
["This medicine must be given only by a healthcare professional.","Use with caution in patients with bleeding disorders or on anticoagulants.","Monitor kidney and liver function during treatment.","Avoid alcohol during treatment.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not use if the solution is discolored or contains particles."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding while receiving this medicine.
💊 Overdose Management
Overdose is unlikely as this medicine is given by healthcare professionals. In case of accidental overdose, seek immediate medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
This medicine is given in a hospital setting, so missed doses are managed by healthcare staff. If you miss an appointment for your injection, contact your doctor as soon as possible to reschedule.
Additional Safety Advice
This medicine must be given only by a healthcare professional in a hospital or clinic setting. Do not attempt to self-administer this injection. Inform your doctor about all medicines you are taking, especially blood thinners, before receiving this medicine. Tell your doctor if you have a history of allergy, bleeding disorders, kidney disease, or liver disease. This medicine is not recommended during pregnancy or breastfeeding unless clearly needed and advised by a specialist. Avoid alcohol while receiving treatment. Report any unusual bleeding, bruising, rash, or difficulty breathing to your doctor immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney and liver function, so dose adjustments may be needed. They should be monitored closely for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss with your doctor before receiving this medicine. It should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used after major surgery to reduce inflammation. It is given under medical supervision, and your doctor will monitor your recovery.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine, especially if you are on blood thinners, as there may be a risk of bleeding.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during acute illness. Gradually resume activity as advised by your doctor. Listen to your body and do not overexert.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital setting, so it may require hospitalization. You may need to take time off work for treatment and recovery. Driving may be unsafe if you feel dizzy or weak. Follow your doctor's advice before resuming work.
🛑 When to Stop This Medicine
This medicine is stopped by your doctor based on your clinical condition. Do not stop treatment on your own. If you experience severe side effects, inform your doctor immediately.
📅 Long-Term Use Effects
Long-term effects of this medicine are not well established. It is typically used for short periods in acute conditions. Monitoring of kidney and liver function may be required if used for prolonged periods. Consult your doctor for any concerns.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Fluids, pain relief, and nutritional support are essential in conditions like pancreatitis.
Evidence: Well-establishedUsed if there is a bacterial infection, especially in sepsis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information.
📦 Storage Guide
✅ DO
Store in a refrigerator (2-8°C)
❌ DON'T
Do not freeze
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to another container
✅ DO
Protect from light
❌ DON'T
Do not use if the solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is given in a hospital setting, so travel advice is limited. If you are traveling after treatment, carry a copy of your prescription and medical records. Store the medicine as advised by your doctor. If you need to continue treatment while traveling, arrange for administration at a healthcare facility at your destination. Always carry the medicine in its original packaging with the prescription label.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine is given as an intravenous or intramuscular injection by a healthcare professional in a hospital or clinic.
A: Common side effects include injection site pain, nausea, vomiting, diarrhea, and skin rash.
A: No, this medicine must be administered by a healthcare professional in a medical setting.
A: It should be used during pregnancy only if clearly needed and prescribed by a specialist.
🤔 Common Patient Concerns
🔄 Substitutes for uliject 100000iu injection
View AllAlternative brands with exact same active ingredient:
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ullinase 100000iu injectionBharat Serums & Vaccines Ltd ₹1,593.75 41.4% CHEAPER
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u bet injectionAbbott ₹1,992.19 26.7% CHEAPER
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miratryp 100000iu injectionAlniche Life Sciences Pvt Ltd ₹2,811.56 3.4% COSTLIER
-
ulinicel 100000iu injectionCelon Laboratories Ltd ₹3,093.75 13.8% COSTLIER
-
uli-vin injectionVinder Pharma ₹3,350.00 23.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be self-administered at home.
Fact: This medicine must be given by a healthcare professional in a hospital or clinic. - Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller; it is a protease inhibitor used for specific inflammatory conditions.