uli-vin injection - Ulinastatin (100000IU) medicine

U Tryp 100000IU Injection: Complete Medicine Guide

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🏭 Vinder Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not classified by FDA letter categories. Use only if clearly needed and prescribed by a specialist. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for some uses; limited for others.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe allergic reaction with drop in blood pressure
  • Unusual bleeding or bruising
  • Decreased urine output
  • Yellowing of skin or eyes
  • Severe abdominal pain or vomiting blood
  • Chest pain or irregular heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is uli-vin injection used for?

This medicine is a protease inhibitor injection used in hospitals to treat acute pancreatitis, severe sepsis, and post-surgical inflammation by reducing excessive inflammation and protecting organs.

  • Generic Name: Ulinastatin (100000IU)
  • Manufacturer: Vinder Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 uli-vin injection के बारे में (Hindi Summary)

उपयोग: यह दवा एक इंजेक्शन है जिसमें यूलिनास्टैटिन नामक सक्रिय तत्व होता है। इसका उपयोग अस्पताल में गंभीर सूजन और ऊतक क्षति को नियंत्रित करने के लिए किया जाता है, जैसे कि तीव्र अग्नाशयशोथ (पैन्क्रियाटाइटिस), गंभीर सेप्सिस, और बड़ी सर्जरी के बाद। यह दवा शरीर में उन एंजाइमों को रोकती है जो सूजन पैदा करते हैं, जिससे अंगों की रक्षा होती है। यह दवा केवल डॉक्टर की देखरेख में ही दी जाती है और घर पर स्वयं नहीं लगाई जानी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द या लालिमा, मतली, उल्टी, दस्त और त्वचा पर चकत्ते शामिल हैं। कभी-कभी लीवर एंजाइम में मामूली वृद्धि या श्वेत रक्त कोशिकाओं में कमी हो सकती है। गंभीर लेकिन दुर्लभ दुष्प्रभावों में तेज एलर्जी प्रतिक्रिया, सांस लेने में कठिनाई, चेहरे या गले में सूजन, और रक्तचाप में अचानक गिरावट शामिल हैं। यदि कोई गंभीर दुष्प्रभाव दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। इसे स्वयं न लगाएं। अपने डॉक्टर को उन सभी दवाओं के बारे में बताएं जो आप ले रहे हैं, विशेष रूप से रक्त पतला करने वाली दवाएं। यदि आपको एलर्जी, रक्तस्राव विकार, गुर्दे या यकृत की बीमारी है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान यह दवा केवल विशेषज्ञ की सलाह पर ही लें। इलाज के दौरान शराब से बचें। असामान्य रक्तस्राव, चकत्ते या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर को बताएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 uli-vin injection Uses & Benefits

[{"condition":"Acute pancreatitis","description":"This medicine is used to reduce inflammation and tissue damage in acute pancreatitis, helping to improve symptoms and outcomes.","evidence":"Well-established in some regions; evidence varies"},{"condition":"Severe sepsis and septic shock","description":"It is used as an adjunctive therapy to control excessive inflammatory response in severe sepsis.","evidence":"Moderate; used in some countries"},{"condition":"Post-surgical inflammation","description":"This medicine may be given after major surgery to reduce inflammation and prevent organ injury.","evidence":"Limited; used in selected cases"},{"condition":"Acute lung injury","description":"It may be used to reduce lung inflammation in conditions like acute respiratory distress syndrome.","evidence":"Limited; not universally accepted"}]

Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Sometimes used off-label to protect kidneys from contrast dye injury.","evidence":"Limited"},{"condition":"Severe burns","description":"May be used to reduce systemic inflammation in severe burn patients.","evidence":"Limited"}]

Primary treatment for: Acute pancreatitis

Also treats: Severe sepsis, Post-surgical inflammation, Acute lung injury

📋 Drug Information

Generic Name(s)Ulinastatin (100000IU)
Brand Nameuli-vin injection
ManufacturerVinder Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassProtease inhibitors- Pancreatitis
Route of AdministrationParenteral (intravenous or intramuscular injection)
StorageStore in a refrigerator (2-8°C). Do not freeze. Keep in the original container to protect from light.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only in a hospital or clinic setting with proper monitoring.
2
Assess renal and hepatic function before and during treatment.
3
Monitor for signs of allergic reactions during and after injection.
4
Use with caution in patients on anticoagulants; monitor coagulation profile.
5
Avoid concurrent use with thrombolytic agents unless clearly necessary.
6
Document the dose, route, and time of administration accurately.
7
Educate the patient about reporting any unusual bleeding or rash.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Severe abdominal pain
This medicine may be used in acute pancreatitis.
Likely Use
✅
Fever with organ dysfunction
This medicine may be used in severe sepsis.
Likely Use
❌
Mild headache
This medicine is not used for mild headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is given by injection, so absorption is not applicable. It is directly introduced into the bloodstream or muscle tissue.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine works by inhibiting a broad range of proteolytic enzymes, including trypsin, chymotrypsin, plasmin, and neutrophil elastase. By blocking these enzymes, it reduces the breakdown of proteins and the activation of inflammatory pathways. This helps to stabilize cell membranes, reduce capillary leakage, and protect organs from inflammatory damage. It also suppresses the release of inflammatory cytokines and reactive oxygen species, contributing to its anti-inflammatory effects.

Mechanism Steps

1
Binding to proteases: This medicine binds to and inhibits enzymes such as trypsin, chymotrypsin, and neutrophil elastase.
2
Reduction of inflammatory mediators: By inhibiting these enzymes, it decreases the production of inflammatory cytokines and free radicals.
3
Stabilization of cell membranes: It helps stabilize cell membranes and reduces capillary permeability, limiting tissue edema.
4
Organ protection: The overall effect is reduced tissue damage and protection of organs such as the pancreas, lungs, and kidneys.

💡 How to Take uli-vin injection

Strength: Injection: 100000 IU

1This medicine is given by a healthcare professional as an injection.
2It is administered intravenously or intramuscularly.
3The injection site will be cleaned before administration.
4You should remain still during the injection.
5Report any pain or discomfort at the injection site immediately.

Dosage Information

Adult DosageThe dose of this medicine is determined by the doctor based on the condition being treated, its severity, and the patient's overall health. It is given as an intravenous or intramuscular injection, often in a hospital setting. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose adjustments may be needed based on kidney and liver function. Consult your doctor.
Renal ImpairmentDose adjustment may be required in patients with kidney disease. Consult your doctor for individualized dosing.
Hepatic ImpairmentDose adjustment may be required in patients with liver disease. Consult your doctor for individualized dosing.
Maximum Daily DoseNot established from the available information.

⏰ What to Do If You Miss a Dose

📌 You miss a scheduled injection appointment
→ Contact your doctor or hospital as soon as possible to reschedule.
💡 Do not attempt to self-administer the missed dose.
📌 You are late for your hospital visit
→ Inform the healthcare staff upon arrival.
💡 They will decide if the dose can still be given or should be skipped.

⚠️ Side Effects of uli-vin injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Usually resolves on its own. Apply a cold compress if needed.
Nausea (Common (5-10%))
Take small sips of water. Inform your doctor if it persists.
Vomiting (Uncommon (1-5%))
Inform your doctor. They may adjust the dose or give an antiemetic.
Diarrhea (Uncommon (1-5%))
Stay hydrated. Consult doctor if it lasts more than a day.
Skin rash (Uncommon (1-5%))
Report to your doctor. May need antihistamine.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you have difficulty breathing, swelling of face or throat, or a sudden drop in blood pressure.
Bleeding (Rare (<0.1%))
Report any unusual bleeding or bruising to your doctor immediately.
Kidney injury (Rare (<0.1%))
Your doctor will monitor kidney function. Report decreased urine output.
Liver enzyme elevation (Rare (<0.1%))
Blood tests may be done. Inform doctor if you notice yellowing of eyes or skin.

⚠️ Rare Side Effects

Leukopenia
Blood tests may be needed. Report any signs of infection.
Thrombocytopenia
Report unusual bruising or bleeding.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Heparin Major
Alteplase Major
NSAIDs Moderate

🚨 Major Interactions

  • Anticoagulants (e.g., warfarin, heparin)
  • Thrombolytic agents (e.g., alteplase)

⚡ Moderate Interactions

  • NSAIDs

🍷 Alcohol Interaction

Alcohol may increase the risk of liver and stomach side effects. It is advisable to avoid alcohol while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to ulinastatin or any component of the injection","Severe bleeding disorders","Pregnancy unless clearly needed","Breastfeeding unless advised by doctor"]

⚠️ Warnings & Precautions

["This medicine must be given only by a healthcare professional.","Use with caution in patients with bleeding disorders or on anticoagulants.","Monitor kidney and liver function during treatment.","Avoid alcohol during treatment.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not use if the solution is discolored or contains particles."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding while receiving this medicine.

💊 Overdose Management

Overdose is unlikely as this medicine is given by healthcare professionals. In case of accidental overdose, seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

This medicine is given in a hospital setting, so missed doses are managed by healthcare staff. If you miss an appointment for your injection, contact your doctor as soon as possible to reschedule.

Additional Safety Advice

General Safety

This medicine must be given only by a healthcare professional in a hospital or clinic setting. Do not attempt to self-administer this injection. Inform your doctor about all medicines you are taking, especially blood thinners, before receiving this medicine. Tell your doctor if you have a history of allergy, bleeding disorders, kidney disease, or liver disease. This medicine is not recommended during pregnancy or breastfeeding unless clearly needed and advised by a specialist. Avoid alcohol while receiving treatment. Report any unusual bleeding, bruising, rash, or difficulty breathing to your doctor immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney and liver function, so dose adjustments may be needed. They should be monitored closely for side effects.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss with your doctor before receiving this medicine. It should be used only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be used after major surgery to reduce inflammation. It is given under medical supervision, and your doctor will monitor your recovery.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine, especially if you are on blood thinners, as there may be a risk of bleeding.

💚 Lifestyle Tips for Better Results

🏃
Follow a low-fat diet if you have pancreatitis.
🥗
Avoid alcohol completely during and after treatment.
😴
Stay well hydrated unless advised otherwise.
💧
Get adequate rest to support recovery.
🧘
Attend all follow-up appointments for monitoring.
🌞
Report any new symptoms promptly.

🏋️ Exercise Considerations

Avoid strenuous exercise during acute illness. Gradually resume activity as advised by your doctor. Listen to your body and do not overexert.

🥗 Diet Recommendations

Eat small, frequent meals if you have pancreatitis.
Avoid fatty and fried foods.
Include plenty of fluids.
Avoid alcohol.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine is given in a hospital setting, so it may require hospitalization. You may need to take time off work for treatment and recovery. Driving may be unsafe if you feel dizzy or weak. Follow your doctor's advice before resuming work.

🛑 When to Stop This Medicine

This medicine is stopped by your doctor based on your clinical condition. Do not stop treatment on your own. If you experience severe side effects, inform your doctor immediately.

📅 Long-Term Use Effects

Long-term effects of this medicine are not well established. It is typically used for short periods in acute conditions. Monitoring of kidney and liver function may be required if used for prolonged periods. Consult your doctor for any concerns.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Supportive care

Fluids, pain relief, and nutritional support are essential in conditions like pancreatitis.

Evidence: Well-established
Antibiotics

Used if there is a bacterial infection, especially in sepsis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store in a refrigerator (2-8°C)

❌ DON'T

Do not freeze

✅ DO

Keep in the original container

❌ DON'T

Do not transfer to another container

✅ DO

Protect from light

❌ DON'T

Do not use if the solution is discolored or contains particles

✈️ Traveling with This Medicine

This medicine is given in a hospital setting, so travel advice is limited. If you are traveling after treatment, carry a copy of your prescription and medical records. Store the medicine as advised by your doctor. If you need to continue treatment while traveling, arrange for administration at a healthcare facility at your destination. Always carry the medicine in its original packaging with the prescription label.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with acute pancreatitis
He was admitted with severe abdominal pain and diagnosed with acute pancreatitis. He received this medicine as part of his treatment. Over the next few days, his pain decreased and inflammatory markers improved. He was monitored closely for any side effects and recovered well.
💡 Lesson: This medicine can help reduce inflammation in acute pancreatitis when given under medical supervision.
👤 A 65-year-old woman with severe sepsis
She was in the intensive care unit with sepsis and organ dysfunction. This medicine was added to her treatment to control the inflammatory response. Her condition gradually stabilized, and she was eventually discharged. She required monitoring of kidney and liver function during treatment.
💡 Lesson: In severe sepsis, this medicine may be used as an adjunct to standard therapy, with close monitoring for side effects.

💬 Questions Patients Often Ask

Q: How is this medicine given?

A: This medicine is given as an intravenous or intramuscular injection by a healthcare professional in a hospital or clinic.

Q: What are the common side effects?

A: Common side effects include injection site pain, nausea, vomiting, diarrhea, and skin rash.

Q: Can I take this medicine at home?

A: No, this medicine must be administered by a healthcare professional in a medical setting.

Q: Is this medicine safe during pregnancy?

A: It should be used during pregnancy only if clearly needed and prescribed by a specialist.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can this medicine be given at home?
  • What are the serious side effects of this medicine?
  • Is this medicine safe for kidney patients?
  • Can this medicine be used in pregnancy?
  • How long does this medicine take to work?
  • Does this medicine interact with blood thinners?

🔄 Substitutes for uli-vin injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be self-administered at home.
    Fact: This medicine must be given by a healthcare professional in a hospital or clinic.
  • Myth: This medicine is a painkiller.
    Fact: This medicine is not a painkiller; it is a protease inhibitor used for specific inflammatory conditions.

📊 Comparison with Similar Medicines

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