ugcold tablet - Levocetirizine (2.5mg) + Paracetamol (325mg) medicine

Ugcold Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Megnesia Neurocare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination evidence is supportive.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is ugcold tablet used for?

This medicine is a combination of Levocetirizine (antihistamine) and Paracetamol (analgesic/antipyretic) used for relief of allergic symptoms like runny nose, sneezing, and mild pain or fever. It is usually taken once or twice daily as prescribed.

  • Generic Name: Levocetirizine (2.5mg) + Paracetamol (325mg)
  • Manufacturer: Megnesia Neurocare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ugcold tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोसेटिरिज़िन और पैरासिटामोल का संयोजन है, जिसका उपयोग एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, खुजली, और आंखों में पानी आना, तथा हल्के दर्द और बुखार के इलाज के लिए किया जाता है। यह आम सर्दी-जुकाम और एलर्जिक राइनाइटिस में राहत देती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, और हल्का पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सूजन, सांस लेने में कठिनाई, या लीवर की समस्या हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब का सेवन न करें क्योंकि इससे लीवर को नुकसान हो सकता है। यदि आपको नींद आती है तो वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 ugcold tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itching, and watery eyes associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from runny nose, sneezing, and mild body ache associated with common cold.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps reduce itching and hives associated with allergic skin reactions.","evidence":"Well-established"},{"condition":"Mild pain and fever","description":"Paracetamol component reduces mild to moderate pain and fever.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Allergic conjunctivitis","description":"Sometimes used off-label to relieve eye itching and redness due to allergies.","evidence":"Limited"},{"condition":"Pruritus due to other causes","description":"May be used off-label for itching not related to allergies, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis, common cold

Also treats: Urticaria, Allergic conjunctivitis

📋 Drug Information

Generic Name(s)Levocetirizine (2.5mg) + Paracetamol (325mg)
Brand Nameugcold tablet
ManufacturerMegnesia Neurocare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol while taking this medicine to prevent liver damage.
3
Do not drive or operate machinery if you feel drowsy.
4
Do not exceed the recommended dose of paracetamol.
5
Consult your doctor if symptoms persist beyond 5 days.
6
Inform your doctor if you have liver or kidney disease.
7
Do not take other paracetamol-containing products simultaneously.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing
This medicine is commonly prescribed for this.
Likely Use
✅
Itching
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
Paracetamol component helps reduce fever.
Likely Use
❌
Severe headache
This medicine is not a primary treatment for severe headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevocetirizine is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 1 hour. Paracetamol is also rapidly absorbed from the gastrointestinal tract, with peak levels within 30-60 minutes.
DistributionLevocetirizine is widely distributed in the body, and about 90% is bound to plasma proteins. Paracetamol distributes throughout most body tissues, with a volume of distribution of about 0.9 L/kg.
Protein BindingLevocetirizine: approximately 90%. Paracetamol: approximately 10-25%.
MetabolismLevocetirizine undergoes minimal metabolism. Paracetamol is metabolized in the liver primarily by glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeLevocetirizine: 6-8 hours. Paracetamol: 2-3 hours.
ExcretionLevocetirizine is excreted mainly unchanged in urine. Paracetamol metabolites are excreted in urine.
BioavailabilityLevocetirizine: high, approximately 100%. Paracetamol: 80-100%.
Onset of ActionLevocetirizine: within 1 hour. Paracetamol: within 30-60 minutes.
Peak Plasma TimeLevocetirizine: 1 hour. Paracetamol: 0.5-1 hour.
Duration of ActionLevocetirizine: 24 hours. Paracetamol: 4-6 hours.

How It Works

Levocetirizine works by selectively blocking histamine H1 receptors, thereby preventing histamine from binding and causing allergic symptoms such as sneezing, itching, and vasodilation. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which reduces pain and fever. The combination provides both antihistaminic and analgesic-antipyretic effects.

Mechanism Steps

1
Histamine H1 receptor blockade: Levocetirizine binds to H1 receptors on cells, preventing histamine from triggering allergic responses.
2
Reduction of allergic symptoms: This blockade reduces sneezing, runny nose, itching, and watery eyes.
3
Central prostaglandin inhibition: Paracetamol inhibits prostaglandin synthesis in the brain, which reduces pain and fever.
4
Analgesic and antipyretic effect: The result is relief from mild pain and lowering of elevated body temperature.

💡 How to Take ugcold tablet

Strength: Tablet containing Levocetirizine 2.5 mg and Paracetamol 325 mg.

1Take the tablet orally with a glass of water.
2Swallow whole; do not crush or chew.
3Can be taken with or without food.
4Follow the prescribed dose and duration.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, or as prescribed by a doctor. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Maximum daily dose of paracetamol should not exceed 4 grams from all sources.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects, especially drowsiness. Dose adjustment may be needed based on kidney and liver function. Consult a doctor.
Renal ImpairmentDose adjustment may be required in patients with kidney impairment. Consult a doctor for appropriate dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction may be necessary. Consult a doctor.
Maximum Daily DoseMaximum daily dose of paracetamol should not exceed 4 grams from all sources. Levocetirizine maximum daily dose is 5 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage and drowsiness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ugcold tablet

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery. Usually resolves with continued use.
Dry mouth (Common (5-10%))
Sip water frequently. Consult doctor if persistent.
Fatigue (Common (5-10%))
Rest well. Consult doctor if it interferes with daily activities.
Nausea (Uncommon (1-5%))
Take with food. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Liver damage (paracetamol overdose) (Rare (<0.1%))
Seek immediate medical help if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop medicine and seek immediate medical attention if you develop rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bleeding, bruising, or infections to your doctor.
Hepatotoxicity
Avoid alcohol and other paracetamol-containing products. Report symptoms of liver injury.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Other paracetamol products Major
CNS depressants Moderate
Anticholinergics Moderate

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Other paracetamol-containing products

⚡ Moderate Interactions

  • CNS depressants (e.g., benzodiazepines, opioids)
  • Anticholinergic drugs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and may worsen drowsiness caused by levocetirizine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to levocetirizine, paracetamol, or any component","Severe liver disease","Severe kidney disease (for levocetirizine)","Children below 6 years (for this combination)"]

⚠️ Warnings & Precautions

["Avoid alcohol while taking this medicine.","Do not exceed the recommended dose of paracetamol.","May cause drowsiness; avoid driving or operating machinery.","Use with caution in patients with liver or kidney disease.","Consult doctor if symptoms persist beyond 5 days.","Do not use for self-medication beyond 3 days without medical advice."]

🤱 Lactation Safety

Levocetirizine and paracetamol may pass into breast milk. Consult your doctor before use during breastfeeding.

💊 Overdose Management

Seek immediate medical attention. Overdose of paracetamol can cause severe liver damage. Symptoms may include nausea, vomiting, abdominal pain, and yellowing of skin. Treatment may include activated charcoal, N-acetylcysteine, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Avoid alcohol while taking this medicine as it can increase the risk of liver damage. Inform your doctor if you have liver or kidney disease, or if you are pregnant or breastfeeding. Do not drive or operate heavy machinery if you feel drowsy. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not use for more than 3-5 days without consulting a doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to drowsiness and anticholinergic effects. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy if you are taking this medicine regularly. The safety of this combination during pregnancy is not fully established.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental issues. It may also interact with anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated to help thin mucus and relieve congestion.
🥗
Get plenty of rest to support your immune system.
😴
Avoid known allergens such as dust, pollen, and pet dander.
💧
Use a humidifier to ease breathing.
🧘
Wash hands frequently to prevent spreading infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel drowsy or weak. Light activities like walking are generally safe. Consult your doctor before resuming intense workouts.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Eat fruits rich in vitamin C to boost immunity.
Avoid cold and processed foods that may worsen symptoms.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Office work is generally safe, but take breaks if you feel sleepy.

🛑 When to Stop This Medicine

Stop taking this medicine if your symptoms improve or as advised by your doctor. Do not stop abruptly if you have been on long-term therapy without consulting your doctor. If you experience any serious side effects, stop and seek medical help immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol can increase the risk of liver damage, especially with alcohol. Levocetirizine may cause tolerance or persistent drowsiness. Regular monitoring of liver and kidney function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion.

Evidence: Well-established
Steam inhalation

Provides temporary relief from nasal congestion.

Evidence: Limited
Antihistamine nasal sprays

Alternative for allergic rhinitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are unwell with fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old woman with seasonal allergic rhinitis
She was prescribed this medicine for sneezing and runny nose. She took it once daily and noticed significant relief within a day. She experienced mild drowsiness initially but it subsided after a few days.
💡 Lesson: Taking the medicine as prescribed provides effective relief from allergic symptoms. Drowsiness is common initially but often improves.
👤 A 45-year-old man with common cold and body ache
He took this medicine twice daily for 3 days. His fever and body ache reduced, and his runny nose improved. He was advised to avoid alcohol and did not experience any side effects.
💡 Lesson: This medicine effectively relieves both cold symptoms and associated mild pain and fever when taken as directed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Levocetirizine starts working within 1 hour, and paracetamol within 30-60 minutes.

Q: Can I take it on an empty stomach?

A: It can be taken with or without food, but taking with food reduces stomach upset.

Q: Is it safe during pregnancy?

A: Consult your doctor before use during pregnancy. The safety is not fully established.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: It only provides symptomatic relief; it does not cure the viral infection.
  • Myth: It is safe to take extra doses for faster relief.
    Fact: Taking extra doses can lead to serious side effects, especially liver damage from paracetamol.

🔄 Alternative Options

Generic Alternatives

  • Levocetirizine + Paracetamol combination tablets from other manufacturers

📊 Comparison with Similar Medicines

[{"medicine":"Levocetirizine + Paracetamol","composition":"Levocetirizine 2.5 mg + Paracetamol 325 mg","onset":"1 hour","duration":"24 hours for antihistamine; 4-6 hours for paracetamol"},{"medicine":"Cetirizine + Paracetamol","composition":"Cetirizine 5 mg + Paracetamol 500 mg","onset":"1 hour","duration":"24 hours for antihistamine; 4-6 hours for paracetamol"}]

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