Alfapsin D 50mg/50000IU Tablet: Complete Information
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is trymosin d tablet used for?
This medicine is a combination of diclofenac and trypsin chymotrypsin used to treat pain and inflammation in conditions like arthritis and soft tissue injuries. It works by reducing prostaglandins and breaking down inflammatory proteins. Take it with food and avoid alcohol.
- Generic Name: Diclofenac (50mg) + Trypsin Chymotrypsin (50000IU)
- Manufacturer: Archicare Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 trymosin d tablet के बारे में (Hindi Summary)
उपयोग: यह दवा दर्द, सूजन और जलन को कम करने के लिए इस्तेमाल की जाती है। यह गठिया, जोड़ों के दर्द, मांसपेशियों की चोट, और सर्जरी के बाद की सूजन में फायदेमंद है। इसमें डाइक्लोफेनाक और ट्रिप्सिन काइमोट्रिप्सिन होते हैं जो सूजन को कम करते हैं और ऊतकों की मरम्मत में मदद करते हैं। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और दस्त शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति और एलर्जी प्रतिक्रिया हो सकती है। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे खाने के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ता है। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। गुर्दे, यकृत, या हृदय की बीमारी हो तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 trymosin d tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness, improving mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps control pain and inflammation in rheumatoid arthritis as an adjunct to disease-modifying therapy.","evidence":"Well-established"},{"condition":"Post-surgical inflammation","description":"Reduces swelling and pain after surgical procedures, including dental and orthopedic surgeries.","evidence":"Moderate"},{"condition":"Soft tissue injuries","description":"Used for sprains, strains, and sports injuries to reduce inflammation and promote healing.","evidence":"Moderate"},{"condition":"Ankylosing spondylitis","description":"Relieves pain and stiffness in ankylosing spondylitis.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, though other NSAIDs are preferred.","evidence":"Limited"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Post-surgical inflammation, Soft tissue injuries
📋 Drug Information
| Generic Name(s) | Diclofenac (50mg) + Trypsin Chymotrypsin (50000IU) |
| Brand Name | trymosin d tablet |
| Manufacturer | Archicare Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Diclofenac inhibits cyclooxygenase-1 and cyclooxygenase-2 enzymes, reducing prostaglandin synthesis and thereby decreasing pain, fever, and inflammation. Trypsin and chymotrypsin are proteolytic enzymes that break down fibrin and other inflammatory proteins, reducing edema and promoting tissue repair. Together, they provide anti-inflammatory, analgesic, and anti-edematous effects.
Mechanism Steps
💡 How to Take trymosin d tablet
Strength: Each tablet contains Diclofenac 50 mg and Trypsin Chymotrypsin 50000 IU.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily with food, as prescribed by your doctor. The dose may vary depending on the condition being treated, severity of symptoms, and your response to therapy. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal and kidney side effects. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction may be necessary. Avoid in severe kidney disease (eGFR <30 mL/min). Consult your doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be necessary. Avoid in severe liver disease. Consult your doctor for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose of diclofenac is 150 mg. Do not exceed this dose. The maximum daily dose of trypsin chymotrypsin is not well established. Follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of trymosin d tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Corticosteroids
- Methotrexate
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Lithium
- SSRIs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver damage. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or gastrointestinal bleeding","Severe kidney disease (eGFR
⚠️ Warnings & Precautions
["Take with food to reduce stomach irritation.","Avoid alcohol during treatment.","Do not use for longer than prescribed without medical advice.","Use with caution in elderly patients due to increased risk of side effects.","Monitor for signs of bleeding, especially if on anticoagulants.","Inform your doctor if you have a history of heart, kidney, or liver disease.","Do not drive if you experience dizziness or drowsiness.","Avoid concomitant use with other NSAIDs."]
🤱 Lactation Safety
Diclofenac is excreted in breast milk in small amounts. Trypsin chymotrypsin is not well studied. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, and kidney failure. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be used if ingestion is recent. Monitor vital signs, kidney function, and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Always take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine because it increases the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, asthma, or bleeding disorders. Do not take other pain relievers or blood thinners without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney injury, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly. Avoid concomitant use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Diclofenac may affect ovulation and is generally avoided during pregnancy, especially in the third trimester. Alternative pain relief options should be discussed.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to reduce pain and swelling. Follow your surgeon's instructions carefully. Monitor for signs of bleeding or infection. Do not use for prolonged periods without medical supervision.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may increase bleeding risk during dental surgery. Your dentist may advise temporary discontinuation or alternative pain management.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you have joint pain or swelling. Gentle stretching and low-impact activities are recommended. Consult your physiotherapist for a safe exercise plan.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Most people can continue their daily activities with caution.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience severe side effects such as black stools, vomiting blood, severe abdominal pain, chest pain, difficulty breathing, or signs of an allergic reaction. Do not stop abruptly if you are on long-term therapy without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney injury, liver damage, and cardiovascular events. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor if you need to use it for more than a few weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help reduce pain and swelling in localized areas.
Evidence: ModerateSome evidence for pain relief in osteoarthritis.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your doctor about this medicine. There is no need to stop the medicine unless advised.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust dosing schedule gradually as advised by your doctor. Declare it at customs if required. Keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30-60 minutes after taking the tablet.
A: No, it should be taken with food to reduce stomach irritation.
A: Long-term use should be under medical supervision with regular monitoring of kidney and liver function.
🤔 Common Patient Concerns
🔄 Substitutes for trymosin d tablet
View AllAlternative brands with exact same active ingredient:
-
alfapsin d 50mg/50000iu tabletHetero Drugs Ltd ₹52.21 7.2% CHEAPER
-
Fibrotryp D 50mg/50000IU TabletAlchemist Life Science Ltd ₹52.67 6.4% CHEAPER
-
chyro d 50mg/50000iu tabletDawn Pharmaceuticals Pvt Ltd ₹54.90 2.4% CHEAPER
-
Trypza K 50mg TabletRidhima Biocare ₹57.09 1.5% COSTLIER
-
chomfit-d tabletBiophar Lifesciences Pvt Ltd ₹60.90 8.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation. - Myth: This medicine is safe for long-term use without monitoring.
Fact: Long-term use requires regular monitoring of kidney and liver function. - Myth: This medicine can be taken with other pain relievers.
Fact: Combining with other NSAIDs increases the risk of side effects.
🔄 Alternative Options
Generic Alternatives
- Diclofenac 50 mg + Trypsin Chymotrypsin 50000 IU tablet
Brand Alternatives
- Alfapsin D 50mg/50000IU Tablet