New Triben-XT Skin Cream: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe swelling of the face, lips, tongue, or throat, or difficulty breathing.
- A sudden, widespread rash or blistering of the skin.
- Signs of a severe allergic reaction such as fever, joint pain, or swollen lymph nodes.
- Increasing pain, redness, warmth, or pus at the application site.
- Yellowing of the skin or eyes, dark urine, or severe stomach pain.
- New tingling, numbness, or burning in the hands or feet.
- Chest pain, palpitations, or fainting.
If experiencing severe symptoms, call emergency services immediately.
What is trioderm-oc cream used for?
This medicine is a topical cream containing terbinafine 1% w/w and ofloxacin 0.75% w/w. It is used to treat skin infections caused by both fungi and bacteria. Apply a thin layer to the affected skin once or twice daily as directed by your doctor. Do not use it in the eyes, nose, or mouth. Complete the full course even if the skin looks better.
- Generic Name: Terbinafine (1% w/w) + Ofloxacin (0.75% w/w)
- Manufacturer: Medpro Biotech
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 trioderm-oc cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक स्किन क्रीम है जिसमें टर्बिनाफाइन 1% w/w और ओफ्लोक्सासिन 0.75% w/w मौजूद होते हैं। यह उन त्वचा संक्रमणों के इलाज के लिए इस्तेमाल की जाती है जो फंगस और बैक्टीरिया दोनों के कारण होते हैं। इसे आमतौर पर एथलीट फुट, दाद, और खुजली वाले संक्रमणों में लगाया जाता है जिनमें बैक्टीरिया भी शामिल हो जाते हैं। यह क्रीम फंगस को मारती है और साथ ही बैक्टीरिया को भी खत्म करती है। इसे सिर्फ त्वचा पर ही लगाना चाहिए। आंखों, नाक, मुंह या शरीर के अंदरूनी हिस्सों में न लगाएं। डॉक्टर के बताए अनुसार ही इसे लगाएं और पूरा कोर्स करें, भले ही त्वचा ठीक लगने लगे।
साइड इफेक्ट्स: इस क्रीम को लगाने पर आमतौर पर हल्के दुष्प्रभाव ही होते हैं। कुछ लोगों को लगाने की जगह पर जलन, खुजली, लालिमा, सूखापन या हल्का दाना निकल सकता है। ये आमतौर पर कुछ समय में ठीक हो जाते हैं। अगर आपको तेज जलन, सूजन, छाले, या त्वचा पर गंभीर रैश हो जाए तो क्रीम लगाना बंद कर दें और डॉक्टर से मिलें। बहुत कम मामलों में धूप से एलर्जी हो सकती है, इसलिए इस दवा का इस्तेमाल करते समय तेज धूप से बचें।
सुरक्षा सलाह: इस क्रीम को सिर्फ त्वचा पर ही लगाएं। लगाने से पहले और बाद में हाथ धोएं। प्रभावित जगह को साफ और सूखा करें, फिर पतली परत में क्रीम लगाएं। आंखों, नाक, मुंह या योनि में न लगाएं। अगर गलती से लग जाए तो तुरंत साफ पानी से धो लें। डॉक्टर के बताए समय तक ही इस्तेमाल करें। इसे बंद डिब्बे में ठंडी और सूखी जगह पर रखें। धूप से बचाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर की सलाह के बिना इसका इस्तेमाल न करें। अगर आपको मधुमेह या कमजोर प्रतिरक्षा प्रणाली है तो डॉक्टर से पूछें।
💊 trioderm-oc cream Uses & Benefits
- [{"condition":"Infected tinea pedis (athlete's foot with bacterial infection)","description":"This medicine is used when athlete's foot caused by a fungus has become secondarily infected with bacteria, leading to redness, inflammation" class="semantic-link" title="Medicines for swelling">swelling, oozing, or foul smell.
- The terbinafine treats the fungus while ofloxacin treats the bacterial component.","evidence":"Well-established for the combination in mixed fungal and bacterial skin infections."},{"condition":"Infected tinea corporis (ringworm with bacterial infection)","description":"Ringworm is a fungal infection that can become itchy and scratched, allowing bacteria to enter.
- This medicine helps clear both the fungal ring and the bacterial infection that may develop on top of it.","evidence":"Well-established for the combination in mixed fungal and bacterial skin infections."},{"condition":"Infected tinea cruris (jock itch with bacterial infection)","description":"Fungal infection in the groin folds can become macerated and infected with bacteria.
- This medicine is used to treat both organisms and reduce inflammation and discharge.","evidence":"Well-established for the combination in mixed fungal and bacterial skin infections."},{"condition":"Eczema with secondary bacterial infection","description":"When eczema skin is broken and becomes infected with bacteria, this medicine may be prescribed to control the bacterial infection while the underlying eczema is treated separately.","evidence":"Limited, based on clinical practice rather than large trials."},{"condition":"Contact dermatitis with secondary bacterial infection","description":"Irritated or allergic skin reactions that become infected with bacteria may be treated with this medicine to cover both the fungal and bacterial aspects if a fungus is also suspected.","evidence":"Limited, based on clinical practice rather than large trials."}]
Off-label uses: [{"condition":"Prevention of infection in minor skin injuries","description":"Some doctors may use this medicine off-label to prevent bacterial and fungal infection in small cuts or abrasions, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Intertrigo of skin folds","description":"Inflammation of skin folds can involve both yeast and bacteria. This medicine may be used off-label when a mixed infection is suspected.","evidence":"Limited"}]
Primary treatment for: Mixed fungal and bacterial skin infections
Also treats: Tinea pedis with secondary bacterial infection, Tinea corporis with secondary bacterial infection, Tinea cruris with secondary bacterial infection, Eczema with secondary bacterial infection, Contact dermatitis with secondary bacterial infection
📋 Drug Information
| Generic Name(s) | Terbinafine (1% w/w) + Ofloxacin (0.75% w/w) |
| Brand Name | trioderm-oc cream |
| Manufacturer | Medpro Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C. Keep the tube tightly closed. Protect from direct sunlight and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. Topical antifungal and antibiotic combinations are used in clinical practice, but specific WHO recommendations for this exact combination are not available. |
| ICMR Guideline | Not established from the available information. ICMR guidelines for skin infections generally recommend topical antifungals for fungal infections and topical antibiotics for bacterial skin infections. The combination may be used when both are present. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains two active ingredients that work in different ways. Terbinafine is an antifungal that blocks the enzyme squalene epoxidase in fungi. This enzyme is needed to convert squalene into ergosterol, which is a key building block of the fungal cell membrane. When ergosterol production stops, squalene builds up inside the fungus and the cell membrane becomes weak, causing the fungus to die. Terbinafine is active against dermatophytes such as Trichophyton, Epidermophyton, and Microsporum species, as well as against Candida yeasts to some extent. Ofloxacin is an antibiotic that belongs to the fluoroquinolone class. It blocks two bacterial enzymes called DNA gyrase and topoisomerase IV. These enzymes are needed for the bacteria to copy and repair their DNA. When they are blocked, the bacteria cannot multiply and are killed. Ofloxacin is active against many gram-positive and gram-negative bacteria that commonly infect the skin, including Staphylococcus aureus and Streptococcus species. Together, the two ingredients treat mixed fungal and bacterial skin infections.
Mechanism Steps
💡 How to Take trioderm-oc cream
Strength: Topical cream containing terbinafine 1% w/w and ofloxacin 0.75% w/w.
Dosage Information
| Adult Dosage | The usual adult dose is to apply a thin layer of this medicine to the affected skin and surrounding area once or twice daily, or as directed by your doctor. The exact frequency and duration depend on the type and severity of the infection. For most skin infections, treatment may continue for 1 to 4 weeks. Wash your hands before and after applying the cream. Do not cover the area with a tight bandage unless your doctor tells you to. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 12 years unless a doctor specifically advises it. |
| Elderly Dosage | Elderly patients can usually use this medicine in the same way as younger adults. However, older adults may have thinner skin and a higher chance of irritation. Apply the cream gently and watch for any signs of skin reaction. If you have kidney or liver problems, tell your doctor before using this medicine. |
| Renal Impairment | No dose adjustment is needed for topical use because systemic absorption is minimal. However, if you have severe kidney disease, inform your doctor before using this medicine. |
| Hepatic Impairment | No dose adjustment is needed for topical use because systemic absorption is minimal. However, if you have severe liver disease, inform your doctor before using this medicine. |
| Maximum Daily Dose | The maximum daily dose depends on the area being treated and the doctor's instructions. Do not apply more than the prescribed amount. For topical use, the usual maximum is twice daily application to the affected area. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of trioderm-oc cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Tizanidine | Major | |
| Theophylline | Moderate | |
| Caffeine | Minor | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Zinc supplements | Minor | |
| Sucralfate | Minor | |
| Other topical quinolones | Moderate | |
| Other topical steroids | Moderate |
🚨 Major Interactions
- Other topical products containing quinolones or steroids
- Tizanidine (oral)
⚡ Moderate Interactions
- Warfarin
- Theophylline
- Caffeine
- Antacids, sucralfate, iron, or zinc supplements
🍷 Alcohol Interaction
Alcohol is not expected to interact with this topical cream because very little of the medicine enters the bloodstream. However, if you drink alcohol heavily, it may affect your general health and immune response, which can slow down healing of skin infections. It is best to avoid excessive alcohol while you are recovering from an infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to terbinafine or any other allylamine antifungal","Allergy to ofloxacin or any other quinolone antibiotic","Use in the eyes, nose, mouth, or vagina","Use on large areas of broken skin without medical advice","Use in children under 12 years without a doctor's recommendation"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, nose, mouth, and other mucous membranes.","Do not use on large areas of skin or for longer than prescribed.","Stop using the cream and consult a doctor if you develop severe irritation or an allergic reaction.","Avoid exposure to strong sunlight or tanning beds while using this medicine, as ofloxacin can rarely cause photosensitivity.","Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Tell your doctor if you have diabetes, poor circulation, or a weakened immune system.","Keep out of reach of children.","Do not use this medicine to treat viral skin infections such as cold sores or chickenpox."]
🤱 Lactation Safety
It is not known whether terbinafine and ofloxacin pass into breast milk in significant amounts after topical use. To be safe, do not apply the cream to the breast area, and avoid applying it to large areas of skin while breastfeeding. If you need to use it on the breast, wash the area thoroughly before feeding. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
This medicine is for external use. Accidental swallowing of the cream is unlikely to cause serious harm because the amounts of active ingredients are small, but it can cause stomach upset. If someone swallows the cream, rinse the mouth with water and contact a doctor or poison control center for advice. Do not induce vomiting unless told to do so by a medical professional. If the cream is applied to a very large area of skin by mistake, wash it off with plenty of water and watch for any unusual symptoms. Seek medical help if you notice dizziness, nausea, or a rash.
⏰ Missed Dose
If you miss a dose of this medicine, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double amount to make up for a missed dose. Try to apply the cream at the same times each day to keep a steady level in the skin and to help you remember.
Additional Safety Advice
Use this medicine only on the skin, exactly as your doctor has told you. Wash your hands thoroughly before and after applying the cream, unless your hands are the area being treated. Clean and dry the affected skin gently before each application. Apply a thin layer of the cream and rub it in lightly. Do not cover the area with a tight bandage or plastic wrap unless your doctor specifically asks you to. Avoid getting the cream in your eyes, nose, mouth, or vagina. If it accidentally gets into these areas, rinse with plenty of clean water. Do not use this medicine on large areas of broken skin or for longer than your doctor recommends, because too much of the medicine may be absorbed into the body. Keep the tube tightly closed when not in use and store it in a cool, dry place away from direct sunlight. Do not share this medicine with anyone else, even if they have similar symptoms. Do not use leftover cream for future skin problems without asking a doctor. If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor before using this medicine. If you have diabetes, poor circulation, or a weakened immune system, ask your doctor before using this cream, because skin infections can be more serious in these conditions. If your symptoms do not improve within the time your doctor advised, or if they get worse, contact your doctor instead of continuing on your own.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults can use this medicine, but their skin may be thinner and more sensitive. Apply the cream gently and watch for any signs of irritation, such as redness, burning, or itching. If irritation occurs, stop the cream and consult a doctor. Older adults with poor circulation or diabetes should check their skin regularly and report any non-healing sores.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before using this medicine. Topical terbinafine and ofloxacin are absorbed in small amounts, and safety data during pregnancy are limited. Your doctor may recommend an alternative treatment if needed. Do not use this medicine without medical advice if you are trying to conceive.
🏥 Post-Surgery Considerations
If you have recently had surgery, do not apply this cream to surgical wounds unless your surgeon has specifically advised it. Surgical wounds need special care, and applying the wrong cream can cause irritation or infection. Tell your surgeon if you are using this medicine before any operation.
🦷 Dental Procedures
This medicine is applied to the skin and does not usually affect dental procedures. However, if you are using it near the mouth or on the face, inform your dentist before any dental work. There are no known interactions with dental anesthetics or antibiotics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can usually continue your normal exercise routine while using this medicine. However, if you have a skin infection in the groin or between the toes, avoid activities that cause excessive sweating or friction until the infection clears. Shower after exercise and dry your skin thoroughly, especially in skin folds. Avoid swimming pools and shared showers if you have an active fungal infection, as you may spread it to others.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied to the skin and is not expected to affect your ability to drive or operate machinery. You can continue your usual work and daily activities. However, if the infection is in an area that causes discomfort, such as between the toes or in the groin, you may find certain activities uncomfortable until it improves. Keep the treated area clean and dry during the day, and follow your doctor's advice about covering the area if needed.
🛑 When to Stop This Medicine
Stop using this medicine and contact your doctor if you develop severe skin irritation, an allergic reaction, or if your symptoms get worse instead of better. Do not stop the medicine early just because the skin looks better, as the infection may return. If you have completed the full course prescribed by your doctor and the infection has cleared, you can stop. If you are unsure, ask your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is not usually recommended unless a doctor advises it. Prolonged use of topical antibiotics like ofloxacin can lead to antibiotic resistance, where bacteria become harder to kill. Prolonged use of topical antifungals can also lead to resistance in fungi. If you need treatment for more than a few weeks, your doctor may reassess your condition and consider other options. Long-term use on large areas of skin may increase the chance of systemic absorption and side effects, although this is rare. Regular follow-up with your doctor is important if you need repeated or prolonged treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Good hygiene helps prevent fungal and bacterial skin infections and supports healing.
Evidence: Well-establishedThis reduces the chance of spreading the infection to other parts of the body or to other people.
Evidence: Well-establishedIf there is no bacterial infection, a topical antifungal alone may be enough. Your doctor will decide if a combination is needed.
Evidence: Well-establishedFor severe or widespread infections, oral medicines may be needed instead of or in addition to topical treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive routine vaccinations while using this cream. If you have an active skin infection, tell the healthcare provider before vaccination, as they may advise waiting until the infection improves.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not freeze the cream.
✅ DO
Keep the tube tightly closed when not in use.
❌ DON'T
Do not leave the tube open or transfer the cream to another container.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom or near a sink.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not use after the expiry date printed on the pack.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you, especially if you are traveling internationally, as some countries may ask for proof that the medicine is for personal use. Store the cream in a cool, dry place and avoid leaving it in a hot car or in direct sunlight. If you are crossing time zones, continue applying the cream at your usual times; there is no need to adjust the schedule for topical medicines. If you are flying, keep the cream in your hand luggage if you need it during the flight, but follow airport rules for liquids and creams. Check customs regulations before carrying prescription medicines into another country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice some improvement in itching and redness within a few days. However, the infection may take 1 to 4 weeks to clear completely, depending on the type and severity. Complete the full course as advised by your doctor.
A: Only use this medicine on your face if your doctor has specifically told you to do so. The skin on the face is delicate and may be more sensitive to irritation.
A: If you remember within a short time, apply the missed dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
A: No. You should complete the full course advised by your doctor, even if the skin looks normal, to prevent the infection from returning.
A: Safety data for this medicine during pregnancy are limited. Use it only if your doctor has clearly advised it. Tell your doctor if you are pregnant or planning pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for trioderm-oc cream
View AllAlternative brands with exact same active ingredient:
-
new triben-xt skin creamJenburkt Pharmaceuticals Ltd ₹48.75 16.1% CHEAPER
-
alnabate forte creamAlna Biotech Pvt Ltd ₹59.00 1.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This medicine is only for specific fungal and bacterial skin infections. Using it for other rashes may cause irritation and delay correct treatment. - Myth: You can stop using the cream as soon as the rash disappears.
Fact: You should complete the full course advised by your doctor, even if the skin looks normal, to prevent the infection from coming back. - Myth: More cream means faster healing.
Fact: Applying more than the recommended amount does not speed up healing and may increase the risk of skin irritation. - Myth: This cream is safe to use on the face without doctor's advice.
Fact: The face has delicate skin. Only use this medicine on the face if your doctor has specifically told you to do so.
🔄 Alternative Options
Generic Alternatives
- Terbinafine 1% w/w + Ofloxacin 0.75% w/w topical cream (generic)
Brand Alternatives
- New Triben-XT Skin Cream