torlactone ls tablet - Spironolactone (25mg) + Torasemide (10mg) medicine

Dytor Plus LS 10 Tablet: Comprehensive Medicine Guide

No reviews yet
🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. Both spironolactone and torasemide are contraindicated in pregnancy due to potential fetal harm. Spironolactone has anti-androgenic effects and torasemide may cause electrolyte imbalances. Use only if clearly needed and prescribed by a specialist. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to high for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Irregular heartbeat or palpitations
  • Muscle weakness or cramps
  • Decreased urine output
  • Swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Blood in stool or vomit

If experiencing severe symptoms, call emergency services immediately.

What is torlactone ls tablet used for?

This medicine is a combination diuretic containing spironolactone and torasemide. It is used to treat fluid retention and high blood pressure. It works by increasing urine output while conserving potassium. It is a prescription drug and requires regular monitoring of kidney function and electrolytes.

  • Generic Name: Spironolactone (25mg) + Torasemide (10mg)
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 torlactone ls tablet के बारे में (Hindi Summary)

उपयोग: यह दवा स्पाइरोनोलैक्टोन और टोरासेमाइड का संयोजन है, जिसका उपयोग शरीर में पानी के जमाव (सूजन) और उच्च रक्तचाप के इलाज के लिए किया जाता है। यह दिल की विफलता, लीवर सिरोसिस और किडनी विकारों में होने वाली सूजन को कम करने में मदद करती है। यह दवा पेशाब की मात्रा बढ़ाकर अतिरिक्त तरल को बाहर निकालती है और पोटैशियम के स्तर को बनाए रखने में मदद करती है। यह केवल डॉक्टर के पर्चे पर ही ली जानी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में बार-बार पेशाब आना, चक्कर आना, सिरदर्द, थकान, मतली और पेट खराब होना शामिल हैं। कुछ रोगियों में पोटैशियम का स्तर बढ़ सकता है, जिससे मांसपेशियों में कमजोरी या दिल की धड़कन अनियमित हो सकती है। स्पाइरोनोलैक्टोन के कारण पुरुषों में स्तन वृद्धि या महिलाओं में मासिक धर्म में गड़बड़ी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में तकलीफ, चेहरे पर सूजन, या पेशाब कम आना जैसी समस्या हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप डोज न बदलें और न ही दवा बंद करें। नियमित रूप से रक्त जांच करवाएं ताकि किडनी, पोटैशियम और सोडियम के स्तर की निगरानी हो सके। पोटैशियम युक्त खाद्य पदार्थ या सप्लीमेंट डॉक्टर की सलाह के बिना न लें। शराब से बचें क्योंकि इससे चक्कर और लो ब्लड प्रेशर हो सकता है। अगर आपको चक्कर आए तो धीरे-धीरे उठें। सर्जरी या डेंटल प्रोसीजर से पहले अपने डॉक्टर को इस दवा के बारे में बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 torlactone ls tablet Uses & Benefits

[{"condition":"Edema in heart failure","description":"Reduces fluid retention and improves symptoms such as shortness of breath and inflammation" class="semantic-link" title="Medicines for swelling">swelling in patients with congestive heart failure.","evidence":"Well-established"},{"condition":"Edema in liver cirrhosis","description":"Helps manage ascites and peripheral edema in patients with cirrhosis, often in combination with other diuretics.","evidence":"Well-established"},{"condition":"Edema in nephrotic syndrome","description":"Used to relieve fluid overload in kidney disorders, though careful monitoring is required.","evidence":"Established"},{"condition":"Resistant hypertension","description":"May be used as add-on therapy for patients whose blood pressure is not controlled with other antihypertensives.","evidence":"Established"}]

Off-label uses: [{"condition":"Polycystic ovary syndrome (PCOS)","description":"Spironolactone component may be used off-label for hirsutism and acne in PCOS, but the combination with torasemide is not standard for this purpose.","evidence":"Limited"},{"condition":"Ascites in malignancy","description":"Occasionally used for symptomatic relief of malignant ascites, but evidence is limited and risks must be weighed.","evidence":"Limited"}]

Primary treatment for: Edema

Also treats: Heart failure, Liver cirrhosis, Nephrotic syndrome, Hypertension

📋 Drug Information

Generic Name(s)Spironolactone (25mg) + Torasemide (10mg)
Brand Nametorlactone ls tablet
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineDiuretics are recommended for symptomatic heart failure and fluid overload. Combination diuretics may be used in resistant cases. However, specific recommendations for this fixed-dose combination are not established from available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine in the morning to avoid frequent urination at night.
2
Monitor your blood pressure regularly and report any dizziness or fainting.
3
Get your potassium and kidney function tested as advised by your doctor.
4
Avoid potassium supplements and salt substitutes unless approved by your doctor.
5
Do not take NSAIDs like ibuprofen without consulting your doctor, as they can reduce the effect of this medicine.
6
Inform your doctor if you experience breast tenderness or swelling.
7
Stay hydrated but follow fluid restrictions if advised.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Swelling in legs or abdomen
This medicine is commonly prescribed for edema.
Likely Use
Shortness of breath due to fluid overload
May be used in heart failure.
Likely Use
High blood pressure
May be used as add-on therapy.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBoth components are absorbed from the gastrointestinal tract after oral administration. Torasemide is rapidly absorbed, with bioavailability around 80-90%. Spironolactone absorption is variable but generally good, and it undergoes extensive first-pass metabolism.
DistributionTorasemide is highly bound to plasma proteins and has a volume of distribution of about 0.2 L/kg. Spironolactone and its active metabolites are also highly protein-bound and distribute widely into tissues.
Protein BindingTorasemide: >99% bound to plasma proteins. Spironolactone: >90% bound to plasma proteins.
MetabolismTorasemide is metabolized in the liver by cytochrome P450 enzymes (mainly CYP2C9) to inactive metabolites. Spironolactone is extensively metabolized in the liver to active metabolites, including canrenone and 7-alpha-thiomethylspirolactone.
Half-LifeTorasemide: approximately 3.5 hours. Spironolactone: parent drug 1.4 hours, but active metabolites have longer half-lives (up to 16 hours).
ExcretionTorasemide is excreted primarily in urine (about 80%) as unchanged drug and metabolites. Spironolactone metabolites are excreted mainly in urine and bile.
BioavailabilityTorasemide: approximately 80-90%. Spironolactone: approximately 90% (but variable due to first-pass effect).
Onset of ActionDiuretic effect begins within 1 hour for torasemide and within 1-2 days for spironolactone. Maximum effect of spironolactone may take 2-3 days.
Peak Plasma TimeTorasemide: 1-2 hours. Spironolactone: 2-4 hours for parent drug, but active metabolites peak later.
Duration of ActionTorasemide: 6-8 hours. Spironolactone: 2-3 days (due to active metabolites).

How It Works

This medicine combines two diuretics with complementary mechanisms. Spironolactone is a competitive antagonist of aldosterone at the mineralocorticoid receptor in the distal tubule and collecting duct, reducing sodium reabsorption and potassium excretion. Torasemide inhibits the Na+/K+/2Cl- cotransporter in the thick ascending limb of the loop of Henle, leading to increased excretion of sodium, chloride, and water. The combination produces a synergistic diuretic effect while spironolactone helps conserve potassium that torasemide would otherwise waste.

Mechanism Steps

1
Spironolactone binds mineralocorticoid receptor: Spironolactone competitively inhibits aldosterone binding in the distal nephron, reducing sodium reabsorption and potassium secretion.
2
Torasemide inhibits NKCC2: Torasemide blocks the sodium-potassium-chloride cotransporter in the thick ascending limb, preventing sodium and water reabsorption.
3
Increased sodium and water excretion: The combined action leads to greater diuresis than either agent alone, reducing extracellular fluid volume.
4
Potassium retention by spironolactone: Spironolactone reduces potassium loss caused by torasemide, helping maintain normal serum potassium levels.
5
Reduced preload and blood pressure: Fluid loss decreases cardiac preload and lowers blood pressure, beneficial in heart failure and hypertension.

💡 How to Take torlactone ls tablet

Strength: Tablet containing spironolactone 25 mg and torasemide 10 mg.

1Take the tablet at the same time each day, preferably in the morning.
2Swallow the tablet whole with a glass of water.
3You may take it with or without food, but taking it with food may reduce stomach upset.
4Do not crush, chew, or break the tablet unless advised by your doctor.
5Follow your doctor's instructions regarding fluid and potassium intake.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, preferably in the morning. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not adjust the dose without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced renal function and increased risk of electrolyte imbalances. Close monitoring is advised.
Renal ImpairmentUse with caution in renal impairment. Dose reduction may be necessary. Contraindicated in anuria and severe renal failure. Monitor renal function regularly.
Hepatic ImpairmentUse with caution in hepatic impairment. Spironolactone may precipitate hepatic coma in severe liver disease. Dose adjustment may be needed.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (spironolactone 25 mg + torasemide 10 mg). Higher doses should only be used under specialist supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Potassium-rich foods
Moderate intake
May increase potassium levels; consult dietitian.
Alcohol
Avoid
Increases risk of low blood pressure and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of torlactone ls tablet

✅ Common Side Effects

Increased urination (Very common (>10%))
This is expected. Adjust timing to avoid nighttime urination. Consult if excessive.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying. Avoid driving if dizzy. Report if persistent.
Headache (Common (5-10%))
Usually resolves. Stay hydrated. Consult if severe.
Fatigue (Common (5-10%))
Ensure adequate rest. Report if interfering with daily activities.
Nausea (Common (5-10%))
Take with food. Consult if persistent.
Breast tenderness or enlargement (gynecomastia) (Common with spironolactone (up to 10%))
Report to doctor; dose adjustment or alternative may be needed.
Menstrual irregularities (Common with spironolactone)
Consult gynecologist if bothersome.

🚨 Serious Side Effects

Hyperkalemia (high potassium) (Uncommon (1-10%))
Seek immediate medical attention if you experience muscle weakness, irregular heartbeat, or paralysis.
Acute kidney injury (Uncommon)
Report decreased urine output, swelling, or confusion immediately.
Severe dehydration and hypotension (Uncommon)
Seek care if you have extreme thirst, very low urine output, or fainting.
Allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you have difficulty breathing, facial swelling, or rash.
Liver toxicity (Rare)
Report yellowing of eyes or skin, dark urine, or abdominal pain.

⚠️ Rare Side Effects

Agranulocytosis
Seek immediate care if you develop fever, sore throat, or mouth ulcers.
Stevens-Johnson syndrome
Go to emergency if you develop painful rash, blisters, or peeling skin.
Pancreatitis
Seek care for severe abdominal pain radiating to back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
ACE inhibitors Major
NSAIDs Major
Lithium Major
Digoxin Major
Potassium supplements Major
Corticosteroids Moderate
Aminoglycosides Moderate
Antacids Minor
Alcohol Moderate

🚨 Major Interactions

  • Potassium supplements
  • ACE inhibitors / ARBs
  • NSAIDs
  • Lithium
  • Digoxin

⚡ Moderate Interactions

  • Corticosteroids
  • Aminoglycosides
  • Anticoagulants (warfarin)

🍷 Alcohol Interaction

Alcohol can enhance the blood pressure-lowering and diuretic effects of this medicine, leading to dizziness, fainting, and dehydration. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Anuria (no urine output)","Acute kidney injury","Severe electrolyte imbalances (hyperkalemia, hyponatremia)","Hypersensitivity to spironolactone, torasemide, or sulfonamides","Pregnancy and breastfeeding","Addison's disease","Concurrent use with potassium supplements or other potassium-sparing diuretics"]

⚠️ Warnings & Precautions

["Monitor potassium levels closely, especially in patients with renal impairment or diabetes.","Avoid in patients with severe liver disease due to risk of hepatic encephalopathy.","Use with caution in elderly patients due to increased risk of dehydration and electrolyte imbalance.","May cause photosensitivity; use sun protection.","Do not use for self-medication; prescription only.","Inform your doctor if you have gout, lupus, or diabetes."]

🤱 Lactation Safety

Spironolactone and torasemide are excreted in breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative options.

💊 Overdose Management

Overdose can cause severe dehydration, electrolyte imbalances, and hypotension. Treatment is supportive and symptomatic. Monitor vital signs, electrolytes, and renal function. There is no specific antidote. In case of overdose, seek immediate medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Regular blood tests to monitor kidney function, potassium, sodium, and blood pressure are essential. Avoid potassium-rich foods or supplements unless your doctor approves them, as this medicine can raise potassium levels. Drink enough water to stay hydrated, but follow your doctor's fluid recommendations if you have heart or kidney failure. Avoid alcohol, as it can worsen dizziness and low blood pressure. Stand up slowly to prevent falls if you feel dizzy. Inform all healthcare providers that you are taking this medicine, especially before surgery or dental procedures. Do not take other diuretics, NSAIDs, or potassium supplements without consulting your doctor. If you miss a dose, follow your doctor's instructions; do not double the dose. Keep this medicine out of reach of children and store it as directed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of dehydration, electrolyte imbalances, and falls due to dizziness. Lower doses and close monitoring are recommended. Regular assessment of renal function and electrolytes is essential.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated in pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to risk of electrolyte imbalances and hypotension. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or increase bleeding risk. Your dentist may need to take precautions, especially if you are also on anticoagulants.

💚 Lifestyle Tips for Better Results

🏃
Follow a low-sodium diet to reduce fluid retention.
🥗
Maintain a healthy weight to reduce strain on the heart and kidneys.
😴
Engage in regular physical activity as tolerated, but avoid strenuous exercise in extreme heat.
💧
Monitor your weight daily and report sudden increases.
🧘
Avoid alcohol and smoking.
🌞
Get adequate rest and manage stress.

🏋️ Exercise Considerations

Avoid strenuous exercise in hot weather as it can worsen dehydration and electrolyte imbalance. Light to moderate exercise is generally safe, but consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Reduce salt intake to less than 2 grams per day.
Avoid potassium-rich foods if your potassium is high.
Include fresh fruits and vegetables, but monitor potassium if advised.
Limit processed foods and canned soups.
Stay adequately hydrated unless fluid restriction is prescribed.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or frequent urination, which can affect driving and operating machinery. Adjust your work schedule if possible to accommodate bathroom breaks. Avoid driving until you know how the medicine affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Stopping suddenly can cause fluid rebound and worsening of heart failure or hypertension. Your doctor may adjust or discontinue based on your condition and lab results.

📅 Long-Term Use Effects

Long-term use requires regular monitoring of kidney function, electrolytes, and blood pressure. Spironolactone can cause endocrine side effects like gynecomastia, which may be reversible upon discontinuation. Torasemide can lead to electrolyte imbalances if not monitored. Periodic dose adjustments may be necessary based on clinical response and laboratory results.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary sodium restriction

Reducing salt intake can help manage fluid retention and complement diuretic therapy.

Evidence: Well-established
Compression stockings

Can help reduce peripheral edema in addition to medication.

Evidence: Established
Regular physical activity

Improves circulation and helps manage blood pressure.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, patients with heart failure or kidney disease should stay up to date with influenza and pneumococcal vaccines as advised by their doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip. Check customs regulations for prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 62-year-old man with heart failure and leg swelling
He was prescribed this medicine along with other heart medications. After a week, his swelling reduced significantly and he could breathe easier. He was advised to monitor his potassium levels regularly. He experienced mild dizziness initially but it subsided after a few days.
💡 Lesson: Regular monitoring and adherence to prescribed dose are key to safe and effective treatment.
👤 A 55-year-old woman with liver cirrhosis and ascites
She started this medicine to manage abdominal swelling. She was advised to follow a low-sodium diet and avoid alcohol. Her symptoms improved, but she required dose adjustments based on her kidney function and potassium levels.
💡 Lesson: Lifestyle modifications and regular follow-up are essential when taking this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Torasemide starts working within 1 hour, while spironolactone may take 2-3 days for full effect.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food, but taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if less than 12 hours have passed. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe during pregnancy?

A: No, this medicine is contraindicated in pregnancy. Consult your doctor for alternative treatment.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for torlactone ls tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken without a prescription.
    Fact: This is a prescription-only medicine and must be taken under medical supervision.
  • Myth: It is safe to take potassium supplements with this medicine.
    Fact: Potassium supplements can cause dangerous hyperkalemia and should be avoided unless prescribed.
  • Myth: This medicine can be stopped once swelling reduces.
    Fact: Stopping suddenly can cause fluid rebound and worsening of the underlying condition. Always consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Spironolactone + Torasemide combination generics

Brand Alternatives

  • Dytor Plus LS 10 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Spironolactone + Torasemide","composition":"Spironolactone 25 mg + Torasemide 10 mg","onset":"1-2 hours","duration":"6-8 hours (torasemide), 2-3 days (spironolactone)","potassium_effect":"Potassium-sparing"},{"medicine":"Spironolactone + Furosemide","composition":"Spironolactone 25 mg + Furosemide 20 mg","onset":"30-60 minutes","duration":"4-6 hours","potassium_effect":"Potassium-sparing"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory