Appacipro Eye Drop: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe eye pain or sudden vision loss
- Swelling of the face, lips, or throat
- Difficulty breathing or swallowing
- Rash or hives covering the body
- Increased redness, swelling, or discharge from the eye
- New or worsening eye pain despite treatment
- Symptoms that do not improve within 3 days of starting treatment
If experiencing severe symptoms, call emergency services immediately.
What is synthocip eye drop used for?
This medicine is an antibiotic eye drop containing ciprofloxacin, used to treat bacterial eye infections such as conjunctivitis and corneal ulcers. It works by killing bacteria that cause infection. Use it exactly as prescribed by your doctor.
- Generic Name: Ciprofloxacin (NA)
- Manufacturer: PCI Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 synthocip eye drop के बारे में (Hindi Summary)
उपयोग: यह दवा सिप्रोफ्लोक्सासिन नामक एंटीबायोटिक की आई ड्रॉप है, जिसका उपयोग बैक्टीरियल आंखों के संक्रमण जैसे कंजंक्टिवाइटिस (आंख आना) और कॉर्नियल अल्सर के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर संक्रमण को ठीक करती है। इसका उपयोग डॉक्टर के बताए अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में आंख में जलन, खुजली, लालिमा, और मुंह में कड़वा स्वाद शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको एलर्जी, सूजन, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी एलर्जी और चिकित्सीय स्थिति के बारे में बताएं। आंखों में डालने से पहले हाथ धोएं। ड्रॉपर की नोक को आंख या किसी सतह को न छुएं। कॉन्टैक्ट लेंस पहनने से पहले डॉक्टर से सलाह लें। पूरा कोर्स पूरा करें, भले ही लक्षण ठीक हो गए हों। बच्चों की पहुंच से दूर रखें।
💊 synthocip eye drop Uses & Benefits
- [{"condition":"Bacterial conjunctivitis","description":"This medicine is used to treat bacterial conjunctivitis, commonly known as pink eye, caused by susceptible bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae.
- It helps relieve symptoms like redness, discharge, and irritation.","evidence":"Well-established"},{"condition":"Corneal ulcers","description":"This medicine is effective in treating corneal ulcers (keratitis) caused by susceptible bacteria.
- It helps prevent complications such as vision loss and scarring.","evidence":"Well-established"},{"condition":"Blepharitis","description":"This medicine may be used to treat bacterial blepharitis, an inflammation of the eyelids, when caused by susceptible organisms.","evidence":"Moderate"},{"condition":"Conjunctivitis prophylaxis in neonates","description":"This medicine may be used to prevent gonococcal ophthalmia neonatorum in newborns, although other agents are often preferred.","evidence":"Limited"},{"condition":"Perioperative prophylaxis","description":"This medicine is sometimes used before or after ocular surgery to prevent postoperative infections.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Trachoma","description":"This medicine may be used off-label for trachoma, a chlamydial infection of the eye, in combination with systemic antibiotics.","evidence":"Limited"},{"condition":"Bacterial keratoconjunctivitis","description":"This medicine may be used off-label for more extensive bacterial infections of the cornea and conjunctiva.","evidence":"Limited"}]
Primary treatment for: Bacterial conjunctivitis
Also treats: Corneal ulcers, Blepharitis, Keratitis, Perioperative prophylaxis
📋 Drug Information
| Generic Name(s) | Ciprofloxacin (NA) |
| Brand Name | synthocip eye drop |
| Manufacturer | PCI Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Ophthalmic |
| Storage | Store at room temperature (15-30°C). Protect from light and excessive heat. Do not freeze. Keep the bottle tightly closed when not in use. Discard 4 weeks after opening. |
| Shelf Life | 24 months from the date of manufacture. Discard 4 weeks after opening the bottle. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication, recombination, repair, and transcription. By blocking these enzymes, ciprofloxacin prevents the supercoiling of bacterial DNA, leading to the inhibition of bacterial growth and ultimately bacterial cell death. This medicine is bactericidal, meaning it kills bacteria directly. It is effective against a wide range of gram-negative and gram-positive bacteria, including Pseudomonas aeruginosa, which is a common cause of serious eye infections.
Mechanism Steps
💡 How to Take synthocip eye drop
Strength: Ophthalmic solution containing ciprofloxacin 0.3% w/v (equivalent to 3 mg/mL).
Dosage Information
| Adult Dosage | The dosage of this medicine must be individualized by a qualified clinician based on the type and severity of the infection, patient age, and response to treatment. For bacterial conjunctivitis, the usual adult dose is 1-2 drops in the affected eye(s) every 2 hours for the first 2 days, then 1-2 drops every 4 hours for the next 5 days. For corneal ulcers, the dose is typically 1-2 drops every 15 minutes for the first 6 hours, then 1-2 drops every 30 minutes for the remainder of the first day, and then 1-2 drops every hour for the next 3 days. Always follow your doctor's instructions precisely. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may use this medicine at the same dosage as adults. However, they may be more susceptible to side effects. Close monitoring is advised. |
| Renal Impairment | No dosage adjustment is required for ophthalmic use in patients with renal impairment, as systemic absorption is minimal. |
| Hepatic Impairment | No dosage adjustment is required for ophthalmic use in patients with hepatic impairment, as systemic absorption is minimal. |
| Maximum Daily Dose | The maximum daily dose for ophthalmic use is not strictly defined, but it should not exceed the prescribed frequency. For adults, the maximum is typically 1-2 drops every 15 minutes for a limited period under medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of synthocip eye drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other ophthalmic antibiotics | Major | |
| Ophthalmic corticosteroids | Major | |
| Oral ciprofloxacin | Moderate | |
| Theophylline | Moderate | |
| Warfarin | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Zinc supplements | Minor | |
| Sucralfate | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Other ophthalmic antibiotics
- Corticosteroids (ophthalmic)
⚡ Moderate Interactions
- Oral ciprofloxacin
- Theophylline
🍷 Alcohol Interaction
There is no known interaction between this medicine and alcohol when used as eye drops. However, alcohol can impair immune function and delay healing, so it is advisable to limit alcohol consumption while recovering from an eye infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to ciprofloxacin or any other fluoroquinolone","Viral or fungal eye infections","History of tendon disorders related to fluoroquinolone use","Myasthenia gravis (may worsen muscle weakness)"]
⚠️ Warnings & Precautions
["Do not use this medicine for viral or fungal eye infections.","Prolonged use may lead to bacterial resistance and secondary infections.","Avoid touching the dropper tip to any surface to prevent contamination.","Remove contact lenses before use and wait 15 minutes before reinserting.","If symptoms do not improve within 2-3 days, consult your doctor.","Do not use this medicine while wearing contact lenses if you have signs of infection.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children.","Do not use after the expiry date.","Discard the bottle 4 weeks after opening, as it may become contaminated."]
🤱 Lactation Safety
It is not known whether ciprofloxacin is excreted in human milk when used as eye drops. However, systemic absorption is minimal, so the risk to a nursing infant is likely low. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with this medicine is unlikely due to its topical nature. If accidental ingestion occurs, drink plenty of water and seek medical attention. If excessive drops are instilled, rinse the eye with lukewarm water. Systemic toxicity is not expected.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before using this medicine, inform your doctor if you are allergic to ciprofloxacin or any other antibiotics. Do not use this medicine if you have a viral or fungal eye infection, as it will not be effective. Wash your hands thoroughly before and after applying the drops to prevent contamination. Avoid touching the dropper tip to your eye or any surface to keep the solution sterile. If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them, as the preservative in the drops may be absorbed by the lenses. Do not share this medicine with others, even if they have similar symptoms. Complete the full course of treatment as prescribed, even if symptoms improve, to prevent recurrence and resistance. If your symptoms do not improve within a few days or worsen, contact your doctor. Do not use this medicine for longer than prescribed without medical advice. Keep this medicine out of reach of children. If you are pregnant or breastfeeding, consult your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, such as eye irritation. They should use it with caution and report any unusual symptoms to their doctor. No dosage adjustment is typically required.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Although systemic absorption is minimal, it is best to discuss the risks and benefits.
🏥 Post-Surgery Considerations
This medicine is sometimes prescribed after eye surgery to prevent infection. Use it exactly as directed by your surgeon. Do not stop using it without consulting your surgeon.
🦷 Dental Procedures
There are no specific considerations for dental procedures while using this medicine. However, inform your dentist about all medications you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There are no specific exercise restrictions while using this medicine. However, if you have blurred vision, avoid activities that require clear vision, such as swimming or contact sports, until your vision returns to normal.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause temporary blurred vision after application. Wait until your vision is clear before driving or operating machinery. You can continue most daily activities, but avoid touching your eyes and maintain good hand hygiene to prevent spreading the infection to others.
🛑 When to Stop This Medicine
Stop using this medicine only after completing the full course prescribed by your doctor, even if symptoms improve. If you experience a serious allergic reaction or severe side effects, stop immediately and seek medical attention. Do not stop prematurely, as this can lead to recurrence of the infection and antibiotic resistance.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless under strict medical supervision. Prolonged use can lead to bacterial resistance, secondary fungal or viral infections, and rarely, corneal deposits. Regular follow-up with your ophthalmologist is advised if long-term therapy is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Applying a warm compress to the affected eye can help relieve discomfort and loosen discharge.
Evidence: Well-established for symptom reliefLubricating eye drops can help soothe irritation, but they do not treat the infection.
Evidence: Supportive careFrequent hand washing and avoiding touching the eyes can prevent the spread of infection.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Discard 4 weeks after opening
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, keep it in your carry-on luggage to prevent exposure to extreme temperatures. Carry it in its original packaging with the prescription label. Bring a copy of your prescription in case you need to show it at customs. If you are traveling across time zones, continue your regular dosing schedule as closely as possible. Store the bottle at room temperature and protect it from direct sunlight. Do not leave it in a hot car. If you are flying, the liquid is allowed in quantities greater than 100 mL if it is medically necessary, but you may need to declare it at security.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel relief within 24-48 hours, but it is important to complete the full course as prescribed. If symptoms do not improve within 3 days, consult your doctor.
A: No, this medicine is only effective against bacterial infections. It will not treat viral or fungal eye infections.
A: Common side effects include temporary burning, stinging, redness, and a bitter taste in the mouth. Serious side effects are rare but include allergic reactions and tendon problems.
A: Ciprofloxacin is category C for pregnancy. However, systemic absorption from eye drops is minimal. Consult your doctor before use.
A: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. Do not wear contacts if you have signs of infection.
A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, this medicine is formulated for ophthalmic use only. Do not use it in the ear unless specifically prescribed by a doctor.
A: Pediatric dosing is not established. Consult a pediatrician for appropriate use in children.
🤔 Common Patient Concerns
🔄 Substitutes for synthocip eye drop
View AllAlternative brands with exact same active ingredient:
-
ciprol eye ointmentEntod Pharmaceuticals Ltd ₹4.82 35.7% CHEAPER
-
Strox Eye DropAlembic Pharmaceuticals Ltd ₹6.50 13.3% CHEAPER
-
larcip eye dropLark Laboratories Ltd ₹6.54 12.8% CHEAPER
-
gercip eye/ear dropsZydus Cadila ₹6.76 9.9% CHEAPER
-
cipdose eye/ear dropsShreya Life Sciences Pvt Ltd ₹7.61 1.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of eye infections.
Fact: This medicine is only effective against bacterial eye infections. It does not work for viral or fungal infections. - Myth: You can stop using this medicine as soon as symptoms improve.
Fact: You must complete the full course as prescribed to prevent recurrence and antibiotic resistance. - Myth: This medicine is safe to use for any eye redness.
Fact: Eye redness can have many causes. This medicine should only be used for bacterial infections diagnosed by a doctor. - Myth: Using this medicine more frequently will make it work faster.
Fact: Using more than prescribed can increase side effects and does not speed up recovery. Follow your doctor's instructions.
🔄 Alternative Options
Generic Alternatives
- Ciprofloxacin ophthalmic solution 0.3%
Brand Alternatives
- Ciplox eye drops
- Cifran eye drops
- Zoxan eye drops