Thrombophob Ointment: Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden swelling, pain, or redness in one leg, especially with warmth
- Chest pain, shortness of breath, or coughing up blood
- Severe allergic reaction: swelling of face, lips, throat, or difficulty breathing
- Unusual bleeding or bruising
- Signs of infection: increased redness, warmth, pus, or fever
- Skin rash or severe itching that worsens
If experiencing severe symptoms, call emergency services immediately.
What is swithromb ointment used for?
This medicine is a topical ointment containing benzyl nicotinate and heparin. It is used to relieve inflammation, swelling, and pain associated with superficial thrombophlebitis, hematomas, and varicose veins. It works by improving local blood flow and preventing blood clotting.
- Generic Name: Benzyl Nicotinate (2mg) + Heparin (50IU)
- Manufacturer: Ind Swift Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 swithromb ointment के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल ऑइंटमेंट है जिसमें बेंज़िल निकोटिनेट और हेपरिन होते हैं। इसका उपयोग सतही थ्रोम्बोफ्लेबिटिस, हेमेटोमा, और वैरिकोज़ वेन्स से जुड़ी सूजन, दर्द और लालिमा को कम करने के लिए किया जाता है। यह रक्त प्रवाह को बेहतर बनाकर और रक्त के थक्के बनने को रोककर काम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा पर लालिमा, जलन, खुजली, या चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी प्रतिक्रिया, सांस लेने में कठिनाई, या असामान्य रक्तस्राव हो सकते हैं। यदि ऐसा हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: केवल बाहरी उपयोग के लिए। आंखों, मुंह, और अन्य श्लेष्म झिल्ली के संपर्क से बचें। खुले घावों पर न लगाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 swithromb ointment Uses & Benefits
[{"condition":"Superficial thrombophlebitis","description":"Relieves inflammation, pain, and swelling associated with inflamed superficial veins, often in the legs.","evidence":"Well-established"},{"condition":"Hematoma","description":"Helps speed the absorption of blood clots under the skin (hematomas) by improving local circulation.","evidence":"Established"},{"condition":"Varicose veins","description":"Provides symptomatic relief from heaviness, pain, and swelling in varicose veins.","evidence":"Limited"},{"condition":"Post-surgical swelling","description":"Reduces swelling and promotes healing after certain surgical procedures.","evidence":"Limited"}]
Off-label uses: [{"condition":"Diabetic neuropathy","description":"Sometimes used off-label to improve blood flow and reduce pain in peripheral neuropathy.","evidence":"Limited"},{"condition":"Raynaud's phenomenon","description":"May be used off-label to improve circulation in fingers and toes during cold-induced vasospasm.","evidence":"Limited"}]
Primary treatment for: Superficial thrombophlebitis
Also treats: Hematoma, Varicose veins, Post-surgical swelling
📋 Drug Information
| Generic Name(s) | Benzyl Nicotinate (2mg) + Heparin (50IU) |
| Brand Name | swithromb ointment |
| Manufacturer | Ind Swift Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Benzyl nicotinate is a nicotinic acid ester that acts as a topical vasodilator. It penetrates the skin and is hydrolyzed to nicotinic acid, which causes dilation of peripheral blood vessels. This leads to increased blood flow, redness, and a warming sensation in the applied area. Heparin, a glycosaminoglycan, binds to antithrombin III and enhances its ability to inactivate thrombin and factor Xa, thereby inhibiting blood coagulation. Additionally, heparin has anti-inflammatory effects by inhibiting the release of inflammatory mediators and reducing edema. Together, these actions help reduce inflammation, swelling, and pain associated with superficial venous conditions.
Mechanism Steps
💡 How to Take swithromb ointment
Strength: Ointment containing Benzyl Nicotinate 2mg and Heparin 50IU per gram.
Dosage Information
| Adult Dosage | Apply a thin layer to the affected area 2-3 times daily or as directed by your doctor. Gently massage until absorbed. The dose and frequency may vary depending on the condition being treated. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients. However, use with caution and follow your doctor's advice. |
| Renal Impairment | No dose adjustment is required for topical use. However, consult your doctor if you have severe kidney disease. |
| Hepatic Impairment | No dose adjustment is required for topical use. However, consult your doctor if you have severe liver disease. |
| Maximum Daily Dose | Not established from the available information. Follow your doctor's prescription. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of swithromb ointment
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Clopidogrel | Major | |
| Ibuprofen | Moderate | |
| Diclofenac | Moderate | |
| Prednisolone | Moderate | |
| Topical antibiotics | Minor |
🚨 Major Interactions
- Oral anticoagulants (e.g., warfarin)
- Antiplatelet agents (e.g., aspirin, clopidogrel)
⚡ Moderate Interactions
- NSAIDs (e.g., ibuprofen, diclofenac)
- Corticosteroids
🍷 Alcohol Interaction
No known interaction with alcohol when used topically. However, alcohol may increase bleeding risk if you have a bleeding disorder or are taking oral anticoagulants.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to benzyl nicotinate, heparin, or any ingredient","Open wounds, cuts, or broken skin","Active bleeding disorders","Severe liver or kidney disease","Application to mucous membranes"]
⚠️ Warnings & Precautions
["For external use only.","Avoid contact with eyes, mouth, and other mucous membranes.","Do not apply to large areas of skin without medical advice.","Do not use on infected or weeping skin.","Consult a doctor if symptoms persist or worsen.","Use with caution in patients with bleeding disorders.","Keep out of reach of children."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before use.
💊 Overdose Management
Overdose is unlikely with topical use. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, flushing, and dizziness. Treatment is supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
For external use only. Apply a thin layer to the affected area and gently rub in until absorbed. Wash your hands before and after application unless your hands are the treated area. Avoid contact with eyes, mouth, nose, and other mucous membranes. Do not apply to open wounds, cuts, or broken skin. Do not cover the treated area with airtight dressings unless instructed by your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Inform your doctor if you have a bleeding disorder or are taking blood-thinning medications. Keep out of reach of children. Do not use if the tube is damaged or the expiry date has passed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to skin irritation and bleeding. Use with caution and monitor for side effects.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are planning to become pregnant. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to reduce swelling and prevent blood clots. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are using this medicine, especially if you have a bleeding disorder or are on anticoagulants, as it may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise that may increase pain or swelling in the affected area. Gentle walking and stretching are usually safe. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or allergic reactions, avoid these activities until you feel better.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your symptoms worsen, if you develop a rash or allergic reaction, or if you do not see improvement within 7 days. Do not stop prescribed treatment without consulting your doctor.
📅 Long-Term Use Effects
Prolonged use over large areas may increase the risk of systemic heparin absorption, leading to bleeding complications. Long-term use should be under medical supervision. Monitor for signs of bleeding or skin thinning.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Using compression stockings to improve blood flow and reduce swelling.
Evidence: Well-establishedElevating the affected limb to reduce swelling.
Evidence: Well-establishedFor more severe cases, oral blood thinners may be prescribed.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, consult your doctor before any vaccination if you are on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling by air, keep it in your carry-on luggage if you need it during the flight. For international travel, check customs regulations regarding topical medications. Avoid exposing the ointment to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may feel a warming sensation within 5-10 minutes, but anti-inflammatory effects may take a few hours to days.
A: No, it should not be applied to open wounds or broken skin.
A: Consult your doctor before use during pregnancy or breastfeeding.
A: Apply as soon as you remember, but if it's almost time for the next dose, skip it and continue with your regular schedule.
🤔 Common Patient Concerns
🔄 Substitutes for swithromb ointment
View AllAlternative brands with exact same active ingredient:
-
thrombotas ointmentIntas Pharmaceuticals Ltd ₹60.94 225% COSTLIER
-
thrombomark ointmentMankind Pharma Ltd ₹69.30 269.6% COSTLIER
-
thromotas creamIntas Pharmaceuticals Ltd ₹71.00 278.7% COSTLIER
-
thrombowock ointmentWockhardt Ltd ₹76.88 310% COSTLIER
-
unithromb ointmentUnimarck Pharma India Ltd ₹90.00 380% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Thrombophob ointment can cure all types of blood clots.
Fact: It is only for superficial clots and inflammation; deep vein thrombosis requires systemic treatment. - Myth: You can apply it to any wound.
Fact: It should not be applied to open wounds or broken skin. - Myth: It is safe to use indefinitely.
Fact: Prolonged use should be under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Benzyl Nicotinate + Heparin ointment (generic)
Brand Alternatives
- Thrombophob ointment