sutharine tablet - Flunarizine (NA) medicine

Sutharine Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Nri Vision Care India Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and prescribed by a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for migraine prophylaxis.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe drowsiness or difficulty staying awake
  • New or worsening depression, thoughts of self-harm
  • Uncontrollable movements of face, tongue, or limbs
  • Severe dizziness or fainting
  • Signs of an allergic reaction: rash, itching, swelling, difficulty breathing
  • Yellowing of skin or eyes (jaundice)

If experiencing severe symptoms, call emergency services immediately.

What is sutharine tablet used for?

This medicine is a calcium channel blocker used to prevent migraines. It is taken orally, usually at bedtime, and works by relaxing blood vessels in the brain.

  • Generic Name: Flunarizine (NA)
  • Manufacturer: Nri Vision Care India Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 sutharine tablet के बारे में (Hindi Summary)

उपयोग: यह दवा माइग्रेन के सिरदर्द को रोकने के लिए इस्तेमाल की जाती है। यह माइग्रेन के दौरे की आवृत्ति और तीव्रता को कम करने में मदद करती है। यह तीव्र माइग्रेन के दौरे के इलाज के लिए नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, थकान, और वजन बढ़ना शामिल हैं। कुछ रोगियों में अवसाद, कंपन, या पार्किंसनिज़्म जैसे गंभीर दुष्प्रभाव भी हो सकते हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी चिकित्सा स्थिति के बारे में बताएं। गाड़ी चलाने या मशीनरी चलाने से बचें क्योंकि यह नींद का कारण बन सकती है। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को अचानक बंद न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 sutharine tablet Uses & Benefits

  • [{"condition":"Migraine prophylaxis","description":"This medicine is used to reduce the frequency and severity of migraine headaches in adults.
  • It is not effective for treating an acute migraine attack.","evidence":"Well-established"},{"condition":"Vestibular vertigo","description":"Sometimes used to treat vertigo due to vestibular disorders, though evidence is limited.","evidence":"Limited"}]

Off-label uses: [{"condition":"Epilepsy adjunct","description":"Occasionally used as an add-on treatment for certain types of epilepsy, but not a first-line therapy.","evidence":"Limited"},{"condition":"Peripheral vascular disease","description":"May be used to improve blood flow in peripheral vascular disease, but evidence is not strong.","evidence":"Insufficient"}]

Primary treatment for: Migraine prophylaxis

Also treats: Vestibular vertigo

📋 Drug Information

Generic Name(s)Flunarizine (NA)
Brand Namesutharine tablet
ManufacturerNri Vision Care India Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassCalcium channel blocker- migraine prevention
Route of AdministrationOral
StorageStore at room temperature (15-30°C), away from moisture and heat. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime to minimize daytime drowsiness.
2
Monitor your weight regularly, as this medicine can cause weight gain.
3
Report any mood changes or unusual movements to your doctor immediately.
4
Do not stop this medicine abruptly; your doctor may need to taper the dose.
5
Avoid alcohol while taking this medicine to prevent increased drowsiness.
6
Use effective contraception if you are of childbearing age, as this medicine may not be safe during pregnancy.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Frequent migraines
This medicine is commonly prescribed for migraine prevention.
Likely Use
❌
Acute migraine attack
This medicine is not for acute treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. The bioavailability is approximately 90%.
DistributionThis medicine is widely distributed throughout the body, including the brain. It is highly protein-bound.
Protein BindingApproximately 90% bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver, primarily by the CYP2D6 enzyme.
Half-LifeThe elimination half-life is approximately 18 days, which allows for once-daily dosing.
ExcretionThis medicine is excreted mainly in the feces via bile, with a small amount excreted in urine.
BioavailabilityApproximately 90%
Onset of ActionThe onset of action for migraine prophylaxis may take several weeks. It may take up to 4-6 weeks to see full benefit.
Peak Plasma TimePeak plasma concentrations are reached within 2-4 hours after oral administration.
Duration of ActionThe effects of this medicine last for about 24 hours, allowing for once-daily dosing.

How It Works

This medicine works by blocking calcium channels in the body, particularly in the blood vessels of the brain. By preventing calcium from entering certain cells, it helps to relax and widen blood vessels, which can improve blood flow and reduce the likelihood of migraine triggers. It also has antihistamine-like effects that may contribute to its efficacy in migraine prevention.

Mechanism Steps

1
Calcium channel blockade: This medicine binds to calcium channels on smooth muscle cells and neurons, preventing calcium influx.
2
Vasodilation: Reduced calcium entry leads to relaxation of cerebral blood vessels, improving blood flow and reducing vasospasm.
3
Neuronal stabilization: By blocking calcium channels in neurons, it stabilizes neuronal activity and reduces cortical spreading depression, which is implicated in migraines.
4
Antihistamine effect: This medicine also has antihistamine properties, which may contribute to its sedative effects and possibly to migraine prevention.

💡 How to Take sutharine tablet

Strength: Tablet, strength not specified in the provided information.

1Take this medicine orally with a glass of water.
2Take it at bedtime to minimize daytime drowsiness.
3Swallow the tablet whole; do not crush or chew.
4Follow your doctor's instructions exactly.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose for migraine prophylaxis is 5-10 mg once daily at bedtime. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects. Start with a lower dose and monitor closely.
Renal ImpairmentNo specific dose adjustment provided. Use with caution in renal impairment.
Hepatic ImpairmentNo specific dose adjustment provided. Use with caution in hepatic impairment.
Maximum Daily Dose10 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit juice
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours late
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours late
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of sutharine tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery until you know how it affects you. If persistent, consult your doctor.
Weight gain (Common (10-20%))
Monitor your weight and diet. Consult a dietitian if needed.
Fatigue (Common (5-10%))
Get adequate rest. If severe, consult your doctor.
Increased appetite (Common (5-10%))
Maintain a balanced diet and exercise regularly.

🚨 Serious Side Effects

Depression (Rare (<1%))
Seek immediate medical attention if you experience persistent sadness, loss of interest, or thoughts of self-harm.
Parkinsonism (Rare (<1%))
Report any tremors, stiffness, or difficulty with movement to your doctor immediately.
Tardive dyskinesia (Very rare (<0.1%))
Seek medical advice if you develop involuntary movements, especially of the face or tongue.

⚠️ Rare Side Effects

Galactorrhea
Consult your doctor if you notice breast milk production unrelated to breastfeeding.
Gynecomastia
Consult your doctor if you notice breast enlargement in men.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Fluoxetine Moderate
Rifampin Moderate

🚨 Major Interactions

  • Alcohol
  • Other CNS depressants (e.g., benzodiazepines, opioids)

⚡ Moderate Interactions

  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • CYP2D6 inducers (e.g., rifampin)

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine, as it can increase drowsiness and dizziness, and may worsen side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to flunarizine","History of depression","Parkinson's disease","Other extrapyramidal disorders","Pregnancy and lactation (unless clearly needed)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","May cause weight gain; monitor weight.","May worsen depression or Parkinson's disease.","Do not stop abruptly; taper under medical supervision.","Use with caution in elderly patients."]

🤱 Lactation Safety

This medicine may pass into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, agitation, and hypotension. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have a history of depression, Parkinson's disease, or any other movement disorder. Do not drive or operate machinery until you know how this medicine affects you, as it can cause drowsiness. Avoid alcohol while taking this medicine, as it can increase drowsiness and dizziness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not stop taking this medicine abruptly without consulting your doctor, as this can lead to withdrawal symptoms. Keep all appointments with your doctor and laboratory for monitoring. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more susceptible to side effects like drowsiness and extrapyramidal symptoms. Use with caution and lower doses may be needed.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. This medicine may not be safe during pregnancy and alternative treatments may be recommended.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and cause increased sedation.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it can cause dry mouth and may interact with certain dental medications.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight through diet and exercise.
🥗
Identify and avoid migraine triggers such as certain foods, stress, and lack of sleep.
😴
Practice relaxation techniques like yoga or meditation.
💧
Stay hydrated and maintain a regular sleep schedule.
🧘
Keep a headache diary to track progress.

🏋️ Exercise Considerations

Avoid strenuous exercise until you know how this medicine affects you, as it can cause drowsiness and dizziness.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit caffeine and alcohol.
Avoid known migraine triggers like aged cheese, chocolate, and processed meats.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause weight gain, which can impact self-esteem.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like depression or movement disorders, contact your doctor immediately; they may advise stopping the medicine.

📅 Long-Term Use Effects

Long-term use may lead to weight gain, depression, and extrapyramidal symptoms. Regular monitoring of weight, mood, and movement disorders is recommended. Periodic review of the need for continued therapy is advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Biofeedback

A relaxation technique that can help reduce migraine frequency.

Evidence: Well-established
Acupuncture

May help reduce migraine frequency and severity.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If crossing time zones, adjust dosing times gradually under medical advice. Check local customs regulations for prescription medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with frequent migraines
She had 4-5 migraines per month that interfered with work. Her doctor prescribed this medicine at bedtime. After 6 weeks, her migraines reduced to 1-2 per month. She experienced mild drowsiness initially, which improved. She also gained 2 kg but managed it with diet and exercise.
💡 Lesson: This medicine can significantly reduce migraine frequency, but side effects like weight gain and drowsiness require monitoring and lifestyle adjustments.
👤 A 50-year-old man with a history of depression
He was prescribed this medicine for migraines but had a history of depression. After a few weeks, he noticed worsening mood and low energy. He reported this to his doctor, who discontinued the medicine and switched to an alternative. His mood improved after stopping.
💡 Lesson: This medicine can worsen depression, so patients with a history of mood disorders should be closely monitored.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: It may take 4-6 weeks to see the full benefit for migraine prevention.

Q: Can I stop taking this medicine suddenly?

A: No, stopping suddenly can cause withdrawal symptoms. Consult your doctor for a tapering schedule.

Q: Is this medicine safe during pregnancy?

A: Consult your doctor. It is not recommended unless clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my weight?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure a migraine attack.
    Fact: This medicine is for prevention, not for treating an acute attack.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Flunarizine

Brand Alternatives

  • Sutharine

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"Calcium channel blocker","primary_use":"Migraine prophylaxis","common_side_effects":"Drowsiness, weight gain"},{"medicine":"Propranolol","class":"Beta-blocker","primary_use":"Migraine prophylaxis","common_side_effects":"Fatigue, cold extremities"},{"medicine":"Topiramate","class":"Anticonvulsant","primary_use":"Migraine prophylaxis","common_side_effects":"Paresthesia, cognitive issues"}]

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