Sustrone 100mg Injection (Testosterone Propionate): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Chest pain, shortness of breath, or coughing up blood
- Sudden weakness or numbness on one side of the body
- Severe leg pain, swelling, or redness
- Yellowing of eyes or skin, dark urine, or severe abdominal pain
- Prolonged painful erection (priapism)
- Severe mood changes, aggression, or thoughts of self-harm
- Rapid weight gain or severe swelling due to fluid retention
If experiencing severe symptoms, call emergency services immediately.
What is sustrone 100mg injection used for?
This medicine is a testosterone propionate injection used for testosterone replacement in men with hypogonadism, for delayed puberty in boys, and in some cases of advanced breast cancer in women. It works by binding to androgen receptors and must be used under medical supervision with regular monitoring.
- Generic Name: Testosterone Propionate (100mg/1ml)
- Manufacturer: Taj Pharma India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sustrone 100mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा टेस्टोस्टेरोन प्रोपियोनेट इंजेक्शन है, जिसका उपयोग पुरुषों में टेस्टोस्टेरोन की कमी (हाइपोगोनाडिज्म) के इलाज के लिए किया जाता है। यह किशोर लड़कों में देर से होने वाले यौवन को शुरू करने और महिलाओं में कुछ विशेष प्रकार के स्तन कैंसर के इलाज में भी सीमित रूप से उपयोग की जाती है। यह दवा शरीर में पुरुष हार्मोन के स्तर को बढ़ाकर मांसपेशियों, हड्डियों, यौन क्षमता और मूड को बेहतर बनाने में मदद करती है। इसका उपयोग केवल डॉक्टर की सलाह और निगरानी में ही किया जाना चाहिए। प्रोस्टेट कैंसर, स्तन कैंसर, गर्भावस्था, स्तनपान, गंभीर लीवर रोग या खून के थक्के की समस्या वाले लोगों को यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन वाली जगह पर दर्द, लालिमा या सूजन, मुँहासे, तैलीय त्वचा, कामेच्छा में बदलाव, मूड में बदलाव और शरीर में पानी का जमाव शामिल हैं। कुछ गंभीर दुष्प्रभावों में खून के थक्के बनना, लीवर की समस्या, प्रोस्टेट रोग का बढ़ना और मानसिक लक्षण शामिल हो सकते हैं। यदि आपको सीने में दर्द, सांस लेने में तकलीफ, पैर में दर्द या सूजन, आँखों या त्वचा का पीला पड़ना, या गंभीर मूड बदलाव महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग केवल डॉक्टर के पर्चे और निगरानी में ही करें। खुद से इंजेक्शन न लगाएं और सुई साझा न करें। अपने डॉक्टर को सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। नियमित रूप से खून की जांच, लीवर फंक्शन और प्रोस्टेट की जांच करवाते रहें। शराब का सेवन कम करें क्योंकि इससे लीवर पर दबाव बढ़ सकता है। यदि आपको सीने में दर्द, सांस लेने में तकलीफ, पैर में दर्द या सूजन, या कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से मिलें।
💊 sustrone 100mg injection Uses & Benefits
[{"condition":"Male hypogonadism","description":"Used as testosterone replacement therapy in men with confirmed low testosterone due to primary or secondary causes, helping restore libido, energy, muscle mass, and bone density.","evidence":"Well-established"},{"condition":"Delayed puberty in boys","description":"May be used under specialist guidance to induce pubertal development in adolescent boys with delayed puberty.","evidence":"Established in specialist practice"},{"condition":"Advanced breast cancer in women","description":"Historically used as hormonal therapy in selected postmenopausal women with advanced breast cancer, though newer agents are generally preferred.","evidence":"Limited and specialist use"},{"condition":"Testosterone deficiency due to testicular or pituitary disease","description":"Replacement therapy for men with documented testosterone deficiency from testicular failure, pituitary disorders, or other endocrine causes.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Athletic performance enhancement","description":"Non-medical use for muscle building or sports performance is illegal in most settings and carries serious health risks.","evidence":"Not recommended"},{"condition":"Male contraception","description":"Testosterone can suppress sperm production, but it is not approved or reliable as a sole contraceptive method.","evidence":"Investigational only"},{"condition":"Osteoporosis in men","description":"Sometimes considered in men with hypogonadism and osteoporosis, but dedicated bone medicines are usually preferred.","evidence":"Limited"}]
Primary treatment for: Male hypogonadism
Also treats: Delayed puberty in boys, Advanced breast cancer in women, Testosterone deficiency due to pituitary or testicular disease
📋 Drug Information
| Generic Name(s) | Testosterone Propionate (100mg/1ml) |
| Brand Name | sustrone 100mg injection |
| Manufacturer | Taj Pharma India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Androgens |
| Route of Administration | Parenteral (intramuscular injection) |
| Storage | Store at room temperature, away from direct sunlight and moisture. Do not freeze. Keep in the original container and out of reach of children. |
| Shelf Life | Refer to the packaging for the exact shelf life. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine delivers testosterone propionate, an ester of the natural androgen testosterone. After injection, esterases release free testosterone, which enters target cells and binds to cytoplasmic androgen receptors. The hormone-receptor complex moves into the nucleus and regulates gene transcription, leading to masculinizing and anabolic effects in tissues such as muscle, bone, prostate, skin, and the central nervous system. It also suppresses gonadotropin release through negative feedback on the pituitary, which reduces endogenous testosterone production and sperm formation.
Mechanism Steps
💡 How to Take sustrone 100mg injection
Strength: Testosterone Propionate 100 mg per 1 ml injection
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and clinical response. For male hypogonadism, typical regimens may involve intramuscular injections of 25 to 50 mg two to three times per week, but exact dosing varies. For delayed puberty, specialist guidance is required. For advanced breast cancer in women, doses are determined by an oncologist. Never self-administer or adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician or pediatric endocrinologist for any use in children or adolescents. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially fluid retention, prostate enlargement, and cardiovascular effects. Doses should be individualized by a clinician with close monitoring. |
| Renal Impairment | Dose adjustment may be needed in patients with kidney disease due to the risk of fluid retention and electrolyte imbalance. Consult a doctor for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in severe liver disease. In mild to moderate liver impairment, use with caution and under close monitoring. Dose adjustment may be necessary. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information and must be determined by a qualified clinician based on the indication and patient factors. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sustrone 100mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Insulin | Major | |
| Corticosteroids | Major | |
| Cyclosporine | Moderate | |
| Thyroid hormones | Moderate | |
| Oxyphenbutazone | Moderate | |
| Propranolol | Minor | |
| Antidiabetic drugs | Minor |
🚨 Major Interactions
- Warfarin and other oral anticoagulants
- Insulin and oral hypoglycemic agents
- Corticosteroids
- Other androgens or anabolic steroids
⚡ Moderate Interactions
- Cyclosporine
- Thyroid hormones
- Oxyphenbutazone
🍷 Alcohol Interaction
Alcohol should be avoided or limited while using this medicine because it can increase the risk of liver toxicity and worsen fluid retention. Chronic heavy alcohol use may also affect hormone levels and reduce the effectiveness of treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to testosterone or any component of the formulation","Male breast cancer or known or suspected prostate cancer","Pregnancy or breastfeeding","Severe liver disease","Active thromboembolic disorders","Polycythemia or high hematocrit","Women with known or suspected breast cancer unless under specialist oncology care"]
⚠️ Warnings & Precautions
["Use only under medical supervision and with regular monitoring.","May cause fluid retention; caution in heart failure, kidney disease, or hypertension.","May increase red blood cell count; monitor hematocrit.","May worsen sleep apnea; monitor if symptoms occur.","Can suppress sperm production and cause testicular shrinkage.","May cause mood changes or psychiatric symptoms.","Avoid use in athletes for performance enhancement; it is illegal and unsafe.","Do not share injection equipment.","Inform your doctor if you have diabetes, heart disease, liver disease, or kidney disease.","Regular prostate examinations are recommended for men over 40."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding because it may pass into breast milk and could harm the infant. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose with this medicine is unlikely to cause life-threatening effects in the short term, but may lead to excessive androgen effects such as priapism, severe fluid retention, or mood disturbances. Treatment is supportive and symptomatic. Seek immediate medical attention if you suspect an overdose. Do not attempt to self-treat.
⏰ Missed Dose
If you miss a dose of this medicine, contact your doctor or follow the prescribed schedule. Do not double the dose to catch up. The dosing interval is usually determined by your doctor based on your condition and response.
Additional Safety Advice
This medicine must only be used under a doctor's prescription and supervision. Do not self-inject or share injection equipment. Inform your doctor about all medicines, supplements, and herbal products you take, especially blood thinners, insulin, corticosteroids, and other hormones. Regular blood tests are needed to monitor red blood cell count, prostate-specific antigen, liver enzymes, and testosterone levels. Avoid alcohol excess because it can worsen liver stress and fluid retention. Use effective contraception if your partner could become pregnant, as this medicine can affect sperm production and is not safe during pregnancy. Do not donate blood while using this medicine without medical clearance. Store the injection as directed and never use it if the solution is cloudy or contains particles. Seek immediate medical help for chest pain, breathlessness, sudden weakness, or severe leg pain.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of prostate enlargement, fluid retention, and cardiovascular events. Doses should be individualized, and regular monitoring of prostate, heart, and kidney function is essential.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated in women who are pregnant or planning pregnancy. Men using this medicine may experience reduced fertility; discuss family planning with your doctor before starting treatment.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are using this medicine before surgery. It may affect fluid balance, blood clotting, and blood sugar levels. Your doctor may advise temporary discontinuation.
🦷 Dental Procedures
Inform your dentist if you are using this medicine, especially before any surgical dental procedure, as it may affect bleeding and healing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid excessive high-intensity training without medical clearance, especially if you have heart or joint problems. Stay hydrated and monitor for unusual fatigue or swelling.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause mood changes, dizziness, or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping suddenly can cause hormone withdrawal symptoms. Your doctor will decide when and how to stop based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of hematocrit, prostate health, liver function, and lipid levels. Prolonged use can lead to polycythemia, increased cardiovascular risk, and suppression of sperm production. It should only be continued under medical supervision with periodic reassessment of benefits and risks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Regular exercise, weight management, and a healthy diet can support hormone balance and overall health.
Evidence: Well-establishedTestosterone gels, patches, or longer-acting injections may be alternatives depending on your needs.
Evidence: Well-establishedFor certain conditions, other treatments may be considered by your doctor.
Evidence: Varies by condition💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, inform your doctor about your vaccination status and any upcoming vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze or refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Check for particles or discoloration before use
❌ DON'T
Do not use if the solution is cloudy or contains particles
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription and a doctor's letter explaining the medical need, especially for international travel. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, consult your doctor about adjusting injection timing. Declare the medicine at customs if required and check local regulations before travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Effects vary by indication. Some men notice improved energy and libido within a few weeks, while full effects on muscle and bone may take several months.
A: It is given as an intramuscular injection by a healthcare professional. Do not self-inject unless trained.
A: Watch for injection site reactions, mood changes, fluid retention, and signs of blood clots such as leg pain or shortness of breath.
A: No, this medicine is contraindicated in men with prostate cancer. Discuss any prostate issues with your doctor before use.
A: No, it is contraindicated during pregnancy and breastfeeding.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is safe for bodybuilding without a prescription.
Fact: Non-medical use of this medicine is illegal, unsafe, and can cause serious health problems including heart and liver damage. - Myth: This medicine can be used as a male contraceptive.
Fact: This medicine is not approved or reliable as a contraceptive and can have serious side effects. - Myth: More frequent injections give better results.
Fact: The dose and frequency must be determined by a doctor; more frequent use can increase side effects.
🔄 Alternative Options
Generic Alternatives
- Testosterone Propionate
Brand Alternatives
- Sustrone 100mg injection