sulfozid 80 tablet - Gliclazide (80mg) medicine

Azukon Tablet: A Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Sidna Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe hypoglycemia (confusion, seizures, loss of consciousness)
  • Signs of allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Yellowing of skin or eyes (jaundice)
  • Unusual bleeding or bruising
  • Severe abdominal pain
  • Persistent nausea or vomiting

If experiencing severe symptoms, call emergency services immediately.

What is sulfozid 80 tablet used for?

This medicine is an oral antidiabetic tablet containing gliclazide 80 mg, used to treat type 2 diabetes by stimulating insulin release from the pancreas.

  • Generic Name: Gliclazide (80mg)
  • Manufacturer: Sidna Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 sulfozid 80 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में इंसुलिन का स्तर बढ़ाकर ब्लड शुगर को कंट्रोल करने में मदद करती है। इसे डॉक्टर की सलाह के अनुसार नाश्ते के साथ लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में लो ब्लड शुगर (हाइपोग्लाइसीमिया), जी मिचलाना, दस्त, और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर हाइपोग्लाइसीमिया, खून की बीमारियां, और एलर्जी शामिल हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को हमेशा खाने के साथ लें। खाना न छोड़ें। लो ब्लड शुगर के लक्षण दिखने पर तुरंत मीठा खाएं। शराब न पिएं। अपने डॉक्टर को अन्य दवाओं के बारे में बताएं। नियमित रूप से ब्लड शुगर की जांच करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 sulfozid 80 tablet Uses & Benefits

[{"condition":"Type 2 diabetes mellitus","description":"Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Type 2 diabetes mellitus

📋 Drug Information

Generic Name(s)Gliclazide (80mg)
Brand Namesulfozid 80 tablet
ManufacturerSidna Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassSulfonylureas (Insulin Secretogogues)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with breakfast or the first main meal of the day to reduce the risk of hypoglycemia.
2
Carry a fast-acting source of glucose, such as glucose tablets or candy, at all times.
3
Monitor your blood sugar levels regularly as advised by your doctor.
4
Avoid alcohol while taking this medicine as it can increase the risk of low blood sugar.
5
Inform your doctor if you experience symptoms of low blood sugar such as shakiness, sweating, or confusion.
6
Do not skip meals while taking this medicine.
7
Consult your doctor before starting or stopping any other medication.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood sugar
This medicine is prescribed for type 2 diabetes.
Likely Use
✅
Frequent urination
May be a symptom of diabetes.
Likely Use
❌
Fever
This medicine is not for fever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration.
DistributionThis medicine is distributed throughout the body, with a volume of distribution of approximately 30 liters.
Protein BindingApproximately 94-97% of this medicine is bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 2C9, to inactive metabolites.
Half-LifeThe elimination half-life of this medicine is approximately 10-12 hours.
ExcretionThis medicine and its metabolites are primarily excreted in the urine.
BioavailabilityThe bioavailability of this medicine is approximately 97%.
Onset of ActionThe onset of action is within 30 minutes to 1 hour after oral administration.
Peak Plasma TimePeak plasma concentrations are reached within 2-4 hours after oral administration.
Duration of ActionThe duration of action is approximately 12-24 hours.

How It Works

This medicine works by binding to specific receptors on the beta cells of the pancreas, leading to closure of ATP-sensitive potassium channels. This causes depolarization of the cell membrane, which opens voltage-gated calcium channels. The resulting influx of calcium stimulates the release of insulin from the pancreatic beta cells. Additionally, it may increase the sensitivity of peripheral tissues to insulin.

Mechanism Steps

1
Binding to sulfonylurea receptor: This medicine binds to the sulfonylurea receptor 1 (SUR1) subunit of the ATP-sensitive potassium channel on pancreatic beta cells.
2
Closure of potassium channels: Binding leads to closure of the ATP-sensitive potassium channels, reducing potassium efflux.
3
Membrane depolarization: The reduction in potassium efflux causes depolarization of the beta cell membrane.
4
Calcium influx: Depolarization opens voltage-gated calcium channels, allowing calcium to enter the cell.
5
Insulin secretion: Increased intracellular calcium triggers the release of insulin from secretory granules.

💡 How to Take sulfozid 80 tablet

Strength: Tablet, 80 mg

1Take this medicine orally with a glass of water.
2Take it with breakfast or the first main meal of the day.
3Swallow the tablet whole; do not crush or chew.
4Follow your doctor's instructions regarding dose and frequency.

Dosage Information

Adult DosageThe usual starting dose is 40-80 mg once daily with breakfast. The dose may be increased gradually based on blood glucose response up to a maximum of 320 mg daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the hypoglycemic effects. Start with a lower dose and monitor closely.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be needed based on creatinine clearance.
Hepatic ImpairmentContraindicated in severe hepatic impairment. Use with caution in mild to moderate impairment.
Maximum Daily Dose320 mg

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With breakfast
Take with food
Reduces risk of hypoglycemia.
Alcohol
Avoid
Increases risk of hypoglycemia and lactic acidosis.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of sulfozid 80 tablet

✅ Common Side Effects

Hypoglycemia (Common (5-10%))
Eat or drink something sugary immediately. If symptoms persist, seek medical help.
Nausea (Common (1-5%))
Take with food. If it persists, consult your doctor.
Diarrhea (Common (1-5%))
Stay hydrated. Consult doctor if severe or persistent.
Headache (Common (1-5%))
Usually resolves on its own. Consult doctor if persistent.

🚨 Serious Side Effects

Severe hypoglycemia (Rare (<0.1%))
Seek immediate medical attention if you experience confusion, seizures, or loss of consciousness.
Blood disorders (e.g., anemia, leukopenia, thrombocytopenia) (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection to your doctor immediately.
Jaundice (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Hemolytic anemia
Consult doctor if you experience unusual fatigue, pale skin, or shortness of breath.
Cholestatic jaundice
Seek medical attention if you notice yellowing of skin or eyes.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Miconazole Major
Phenylbutazone Major
Beta-blockers Moderate
Corticosteroids Moderate
Thiazide diuretics Moderate
Alcohol Major

🚨 Major Interactions

  • Miconazole
  • Phenylbutazone
  • Alcohol

⚡ Moderate Interactions

  • Beta-blockers
  • Corticosteroids
  • Thiazide diuretics

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine as it can increase the risk of hypoglycemia and may precipitate lactic acidosis.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe hepatic impairment","Severe renal impairment","Hypersensitivity to gliclazide or other sulfonylureas","Pregnancy and lactation"]

⚠️ Warnings & Precautions

["Risk of hypoglycemia, especially in elderly, malnourished, or those with renal/hepatic impairment.","Avoid alcohol consumption.","May cause weight gain.","Use with caution in patients with G6PD deficiency.","May increase risk of cardiovascular events.","Not for use in type 1 diabetes."]

🤱 Lactation Safety

This medicine is excreted in breast milk. Consult your doctor before breastfeeding. Monitor infant for hypoglycemia.

💊 Overdose Management

Overdose can cause severe hypoglycemia. Treatment includes immediate administration of glucose and close monitoring. In severe cases, hospitalization with intravenous glucose and supportive care may be required.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Always take this medicine with food to lower the risk of hypoglycemia. Do not skip meals while on this medicine. Carry a fast-acting source of sugar, such as glucose tablets or candy, to treat low blood sugar if it occurs. Avoid alcohol as it can increase the risk of low blood sugar and lactic acidosis. Inform your doctor if you have liver or kidney problems, as dose adjustments may be needed. Regularly monitor your blood sugar levels as advised by your doctor. Do not drive or operate heavy machinery if you experience symptoms of low blood sugar. Tell your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of hypoglycemia. Start with a lower dose and monitor blood sugar closely. Regular assessment of renal function is recommended.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative, such as insulin.

🏥 Post-Surgery Considerations

Blood sugar levels may fluctuate after surgery. Close monitoring and dose adjustments may be needed. Inform your surgeon and anesthesiologist about this medicine.

🦷 Dental Procedures

Inform your dentist about this medicine. Maintain good oral hygiene. If you need to fast before a procedure, consult your doctor about dose adjustments.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight through diet and exercise.
🥗
Follow a balanced diet rich in fiber and low in refined sugars.
😴
Engage in regular physical activity, such as walking or swimming.
💧
Monitor your blood sugar levels regularly.
🧘
Avoid smoking and limit alcohol consumption.
🌞
Get adequate sleep and manage stress.

🏋️ Exercise Considerations

Exercise can lower blood sugar levels. Monitor your blood sugar before and after exercise, and carry a source of glucose. Adjust your medication dose if advised by your doctor.

🥗 Diet Recommendations

Eat regular meals and do not skip breakfast.
Include complex carbohydrates, lean proteins, and healthy fats.
Limit intake of sugary drinks and processed foods.
Stay hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause low blood sugar, which can affect your ability to drive or operate machinery. Avoid these activities if you feel shaky, dizzy, or confused. Inform your employer about your condition if necessary.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your blood sugar is well controlled with lifestyle changes, your doctor may adjust or stop the medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to weight gain and increased risk of hypoglycemia. Regular monitoring of blood sugar, HbA1c, and liver/kidney function is recommended. It may also lose effectiveness over time, requiring addition of other antidiabetic agents.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise can help control blood sugar and may reduce the need for medication.

Evidence: Well-established
Other antidiabetic medicines

Metformin, DPP-4 inhibitors, SGLT2 inhibitors, etc., may be used as alternatives or in combination.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, maintain up-to-date vaccinations as advised for people with diabetes.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. When traveling across time zones, adjust the timing of your dose in consultation with your doctor to avoid hypoglycemia. Keep a supply of glucose tablets handy. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with type 2 diabetes
He was prescribed this medicine 80 mg once daily with breakfast. After a few weeks, his blood sugar levels improved significantly. He learned to recognize early signs of low blood sugar and always carried glucose tablets.
💡 Lesson: Taking the medicine with food and monitoring blood sugar helps achieve good control and prevents complications.
👤 A 62-year-old woman with type 2 diabetes and mild kidney disease
She started on a lower dose of this medicine due to her kidney function. With regular monitoring, her diabetes was well controlled without any episodes of low blood sugar.
💡 Lesson: Dose adjustment in kidney disease is important to prevent hypoglycemia.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood sugar within 30 minutes to 1 hour, but it may take several days to weeks to see the full effect on blood sugar control.

Q: Can I take this medicine if I have kidney disease?

A: It can be used with caution in kidney disease, but the dose may need adjustment. Consult your doctor.

Q: What should I do if I experience low blood sugar?

A: Immediately eat or drink something sugary, such as glucose tablets, candy, or fruit juice. If symptoms persist, seek medical help.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for sulfozid 80 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure diabetes.
    Fact: This medicine helps control blood sugar but does not cure diabetes.
  • Myth: This medicine can be taken without food.
    Fact: It should be taken with food to reduce the risk of low blood sugar.

🔄 Alternative Options

Generic Alternatives

  • Gliclazide 80 mg tablet

Brand Alternatives

  • Diamicron
  • Glycinorm
  • Glimer

📊 Comparison with Similar Medicines

[{"medicine":"Gliclazide","class":"Sulfonylurea","duration":"12-24 hours","hypoglycemia_risk":"Moderate"},{"medicine":"Glimepiride","class":"Sulfonylurea","duration":"24 hours","hypoglycemia_risk":"Moderate"},{"medicine":"Metformin","class":"Biguanide","duration":"6-12 hours","hypoglycemia_risk":"Low"}]

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