sterobet nm cream - Clobetasol (0.05% w/w) + Miconazole (2% w/w) medicine

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🏭 Trans Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe burning, itching, or rash that worsens after application
  • Signs of skin thinning, such as shiny, transparent skin or easy bruising
  • New or worsening infection with pus, pain, or fever
  • Symptoms of adrenal suppression: extreme fatigue, weakness, dizziness, or low blood pressure
  • Allergic reaction: swelling of face, lips, tongue, or difficulty breathing
  • No improvement after 1 week of use

If experiencing severe symptoms, call emergency services immediately.

What is sterobet nm cream used for?

This medicine is a topical cream combining clobetasol (a strong steroid) and miconazole (an antifungal). It treats inflamed fungal skin infections like ringworm with redness and itching. Apply a thin layer to the affected area once or twice daily for up to 2 weeks, as prescribed.

  • Generic Name: Clobetasol (0.05% w/w) + Miconazole (2% w/w)
  • Manufacturer: Trans Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 sterobet nm cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें क्लोबेटासोल (एक शक्तिशाली स्टेरॉयड) और माइकोनाज़ोल (एक एंटीफंगल) शामिल हैं। इसका उपयोग सूजन वाले फंगल संक्रमण जैसे दाद, खुजली और जॉक इच के इलाज के लिए किया जाता है। यह खुजली, लालिमा और सूजन को कम करता है और फंगस को मारता है। इसे प्रभावित त्वचा पर पतली परत में लगाएं, दिन में एक या दो बार, डॉक्टर के निर्देशानुसार।

साइड इफेक्ट्स: आम दुष्प्रभावों में जलन, खुजली, सूखापन या लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं। कोई भी असामान्य लक्षण होने पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस क्रीम को केवल प्रभावित त्वचा पर ही लगाएं। आंखों, मुंह और श्लेष्मा झिल्ली से बचें। बिना डॉक्टर की सलाह के 2 सप्ताह से अधिक उपयोग न करें। बच्चों में विशेषज्ञ की सलाह के बिना उपयोग न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 sterobet nm cream Uses & Benefits

[{"condition":"Inflammatory tinea corporis","description":"Treats ringworm of the body with significant inflammation, reducing redness and itching while eliminating the fungus.","evidence":"Well-established"},{"condition":"Inflammatory tinea cruris","description":"Treats jock itch with inflammation, providing rapid symptom relief and antifungal action.","evidence":"Well-established"},{"condition":"Inflammatory tinea pedis","description":"Treats athlete's foot with marked inflammation, reducing swelling and killing the fungus.","evidence":"Well-established"},{"condition":"Candidal intertrigo","description":"Treats yeast infections in skin folds with inflammation, combining antifungal and anti-inflammatory effects.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Seborrheic dermatitis with suspected fungal component","description":"Sometimes used when both inflammation and Malassezia are suspected, but not first-line.","evidence":"Limited"}]

Primary treatment for: Inflammatory fungal skin infections

Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Candidal intertrigo

📋 Drug Information

Generic Name(s)Clobetasol (0.05% w/w) + Miconazole (2% w/w)
Brand Namesterobet nm cream
ManufacturerTrans Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore below 30°C. Do not freeze. Keep in a cool, dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer only to the affected area and rub it in gently.
2
Do not use this cream on the face, groin, or underarms unless specifically prescribed.
3
Limit treatment to 2 weeks to avoid skin thinning and other steroid side effects.
4
If the infection does not improve within 1 week, consult your doctor.
5
Do not share this cream with others, even if they have similar symptoms.
6
Wash your hands after applying unless your hands are the treated area.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Itchy, red, ring-shaped rash
This medicine is commonly prescribed for inflammatory fungal infections like ringworm.
Likely Use
Jock itch with redness and itching
This medicine can treat inflammatory tinea cruris.
Likely Use
Athlete's foot with inflammation
This medicine is used for inflammatory tinea pedis.
Likely Use
Acne
This medicine is not for acne and can worsen it.
Not Primary
Bacterial skin infection
This medicine is not effective against bacteria and may worsen infection.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClobetasol propionate is absorbed through the skin, especially when used on large areas, under occlusion, or on thin skin. Miconazole nitrate is minimally absorbed through intact skin. Systemic absorption of both is low with normal use.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismClobetasol is metabolized in the liver, primarily by CYP3A4. Miconazole is metabolized in the liver and inhibits CYP3A4 and CYP2C9.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionItching and redness may begin to improve within a few hours to days. Full antifungal effect may take 1-2 weeks.
Peak Plasma TimeNot established from the available information.
Duration of ActionAnti-inflammatory effect lasts several hours after application; antifungal effect persists with regular use.

How It Works

This medicine combines two active ingredients. Clobetasol propionate is a very potent topical corticosteroid that binds to glucocorticoid receptors in the skin, leading to suppression of inflammatory mediators and immune cells. This reduces redness, swelling, and itching. Miconazole nitrate is an imidazole antifungal that inhibits the enzyme lanosterol 14-alpha-demethylase, disrupting the synthesis of ergosterol, a key component of the fungal cell membrane. This leads to increased membrane permeability and fungal cell death. Together, they provide rapid symptomatic relief and treat the fungal infection.

Mechanism Steps

1
Clobetasol binds to glucocorticoid receptors: Clobetasol enters skin cells and binds to cytoplasmic glucocorticoid receptors, forming a complex that translocates to the nucleus.
2
Suppression of inflammatory genes: The complex inhibits transcription of pro-inflammatory cytokines and enzymes, reducing inflammation and immune cell activity.
3
Miconazole inhibits ergosterol synthesis: Miconazole binds to fungal cytochrome P450 enzyme lanosterol 14-alpha-demethylase, blocking conversion of lanosterol to ergosterol.
4
Fungal cell membrane damage: Without ergosterol, the fungal cell membrane becomes permeable, leading to leakage of cellular contents and cell death.

💡 How to Take sterobet nm cream

Strength: Cream containing clobetasol propionate 0.05% w/w and miconazole nitrate 2% w/w.

1Wash and dry the affected area gently.
2Apply a thin layer of cream to the affected skin.
3Rub it in gently until it disappears.
4Wash your hands after applying, unless hands are being treated.
5Do not cover the area with bandages or dressings unless instructed.
6Use only for the prescribed duration.

Dosage Information

Adult DosageApply a thin layer to the affected area once or twice daily, as directed by your doctor. The duration of treatment should not exceed 2 weeks without medical advice. Dose must be individualized by a qualified clinician based on the condition, severity, and response to treatment.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to skin thinning and systemic effects. Use with caution and for the shortest duration possible.
Renal ImpairmentNo dose adjustment needed for topical use. However, consult doctor if you have severe kidney disease.
Hepatic ImpairmentNo dose adjustment needed for topical use. However, consult doctor if you have severe liver disease.
Maximum Daily DoseNot established from the available information. Use only as prescribed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of sterobet nm cream

✅ Common Side Effects

Burning or stinging at application site (Common (5-10%))
Usually resolves with continued use. If severe, stop and consult doctor.
Itching (Common (5-10%))
May be due to the medicine or the condition. Consult doctor if persistent.
Dryness or scaling (Common (5-10%))
Use a moisturizer if needed. Consult doctor if severe.
Redness or irritation (Common (5-10%))
Usually temporary. If worsens, stop and consult doctor.

🚨 Serious Side Effects

Skin thinning (atrophy) (Uncommon (0.1-1%))
Stop use and consult doctor if skin becomes thin, shiny, or easily bruised.
Stretch marks (striae) (Uncommon (0.1-1%))
Stop use and consult doctor if new stretch marks appear.
Adrenal suppression (Rare (<0.1%))
Seek medical attention if you experience fatigue, weakness, or low blood pressure.
Secondary infection (Rare (<0.1%))
Consult doctor if the treated area becomes more red, swollen, or painful.

⚠️ Rare Side Effects

Allergic contact dermatitis
Stop use and seek medical advice if you develop a rash, hives, or swelling.
Cushing's syndrome
Seek medical attention if you notice weight gain, moon face, or easy bruising.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Warfarin Moderate
Ritonavir Major
Oral hypoglycemics Moderate

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • Warfarin
  • Oral hypoglycemics

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol may worsen certain skin conditions. Consult your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to clobetasol, miconazole, or any component of the formulation","Untreated bacterial or viral skin infections (e.g., impetigo, herpes simplex)","Acne vulgaris, rosacea, perioral dermatitis","Use on the face, groin, or axillae unless directed by a doctor","Children under 12 years (unless prescribed by a specialist)"]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas or for longer than 2 weeks without medical advice.","Do not use with occlusive dressings unless directed.","If irritation or sensitization occurs, discontinue and consult a doctor.","Use in children may cause HPA axis suppression; use with caution.","Pregnancy and breastfeeding: consult doctor before use."]

🤱 Lactation Safety

It is not known if clobetasol or miconazole pass into breast milk in significant amounts after topical use. However, caution is advised. Do not apply to the breast area before breastfeeding. Consult your doctor.

💊 Overdose Management

Overdose is unlikely with topical use. If accidental ingestion occurs, seek medical attention. Prolonged excessive use may cause systemic steroid effects; manage symptomatically and consult a doctor.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply a thin layer to the affected area only, and rub it in gently. Do not cover the area with bandages or dressings unless your doctor tells you to. Avoid contact with eyes, mouth, and other mucous membranes. Wash your hands after applying, unless your hands are the treated area. Do not use this medicine for more than two weeks without medical advice. Do not use it on children under 12 years without a doctor's supervision. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not use it on broken skin or open wounds.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to skin thinning and systemic effects from topical steroids. Use the lowest effective dose for the shortest duration. Monitor for signs of adrenal suppression.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning pregnancy, or breastfeeding. Topical corticosteroids should be used with caution during pregnancy.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine on surgical wounds. It may delay wound healing and increase risk of infection.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or bedding to prevent spread of infection.
😴
Wear loose-fitting, breathable clothing.
💧
Avoid scratching the affected area to prevent worsening.
🧘
Complete the full course of treatment even if symptoms improve.

🏋️ Exercise Considerations

No specific exercise restrictions. However, avoid activities that cause excessive sweating or friction on the affected area until it heals.

🥗 Diet Recommendations

Eat a balanced diet to support immune function.
Include probiotics like yogurt to support gut health.
Stay hydrated.
Limit sugary and processed foods.

💼 Impact on Daily Work & Life

This medicine is applied to the skin and is unlikely to affect your ability to work or drive. However, if you experience any dizziness or unusual symptoms, avoid driving or operating machinery.

🛑 When to Stop This Medicine

Stop using this medicine after the prescribed duration or if your doctor advises. If you experience severe irritation, allergic reaction, or signs of skin thinning, stop and consult your doctor immediately. Do not stop abruptly if you have been using it for a long time without medical advice.

📅 Long-Term Use Effects

Prolonged use of this medicine can lead to skin thinning, stretch marks, and increased risk of systemic steroid effects such as adrenal suppression. It should only be used for short periods as prescribed. Regular monitoring by a doctor is advised if extended use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungal alone

If inflammation is mild, a plain antifungal cream may be sufficient.

Evidence: Well-established
Oral antifungal

For extensive or resistant infections, oral antifungals may be prescribed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. However, consult your doctor before vaccination if you are using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription. Store at room temperature, away from direct sunlight. If traveling to a different time zone, continue applying as prescribed; no time adjustment needed for topical use. Declare it at customs if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with itchy, red ring-shaped rash on his arm
He was prescribed this cream for inflammatory tinea corporis. He applied it twice daily as directed. Within 3 days, the itching and redness reduced significantly. He completed the 2-week course and the rash cleared completely. He was advised not to use it longer than prescribed.
💡 Lesson: Using the cream exactly as prescribed and for the full duration helps clear the infection and prevents recurrence.
👤 A 28-year-old woman with jock itch and severe inflammation
She used this cream for 10 days. The inflammation subsided quickly, but she stopped using it after 5 days because she felt better. The infection returned. Her doctor explained that the antifungal needs to be used for the full course even if symptoms improve.
💡 Lesson: Do not stop treatment early, even if symptoms improve, to ensure the fungus is completely eradicated.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Itching and redness may start improving within a few hours to days. The fungal infection may take 1-2 weeks to clear completely.

Q: Can I stop using it when symptoms improve?

A: No, you should complete the full course as prescribed to prevent the infection from returning.

Q: Is this cream safe for long-term use?

A: No, it should not be used for more than 2 weeks without medical advice due to risk of skin thinning and other side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this cream on my face?
  • How long can I use this cream?
  • Is it safe for children?
  • Can I use it during pregnancy?
  • What if I miss a dose?
  • Can I use it with other creams?

🔄 Substitutes for sterobet nm cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This cream can be used for any skin rash.
    Fact: It is only for inflamed fungal infections. Using it for other rashes can worsen the condition.
  • Myth: It is safe to use for long periods.
    Fact: Prolonged use can cause skin thinning and other side effects. Use only as prescribed, usually up to 2 weeks.
  • Myth: More cream means faster healing.
    Fact: Applying more than a thin layer does not help and may increase side effects.

🔄 Alternative Options

Generic Alternatives

  • Clobetasol + Miconazole cream

Brand Alternatives

  • Lobate-GM Neo Cream

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Clobetasol 0.05% + Miconazole 2%","potency":"Very potent steroid","indications":"Inflammatory fungal infections"},{"medicine":"Clobetasol + Clotrimazole","active_ingredients":"Clobetasol 0.05% + Clotrimazole 1%","potency":"Very potent steroid","indications":"Inflammatory fungal infections"}]

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