Bariderm F Cream: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe burning, blistering, or swelling at the application site.
- Signs of an allergic reaction such as rash, itching, swelling of the face, lips, or throat, or difficulty breathing.
- Vision changes or eye pain, which may indicate increased intraocular pressure or glaucoma.
- Signs of systemic corticosteroid effects such as rapid weight gain, moon face, easy bruising, or extreme fatigue.
- Signs of infection worsening or spreading despite treatment, such as increased redness, warmth, pain, or pus.
- Symptoms of adrenal insufficiency such as weakness, nausea, vomiting, low blood pressure, or dizziness.
- Severe skin thinning, stretch marks, or visible blood vessels in the treated area.
If experiencing severe symptoms, call emergency services immediately.
What is sterk-fd cream used for?
This medicine is a topical cream containing clobetasol (a strong steroid) and fusidic acid (an antibiotic). It is used to treat inflamed skin conditions that have become infected. Apply a thin layer to the affected area as prescribed, usually once or twice daily, for up to 2 weeks. Do not use on the face or for prolonged periods without medical advice.
- Generic Name: Clobetasol (0.05% w/w) + Fusidic Acid (2% w/w)
- Manufacturer: Solace Biotech Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sterk-fd cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें क्लोबेटासोल (एक शक्तिशाली स्टेरॉयड) और फ्यूसिडिक एसिड (एक एंटीबायोटिक) शामिल हैं। इसका उपयोग त्वचा की सूजन वाली स्थितियों के इलाज के लिए किया जाता है जो संक्रमित हो गई हैं, जैसे कि संक्रमित एक्जिमा, डर्मेटाइटिस, या सोरायसिस। यह खुजली, लालिमा और सूजन को कम करता है और साथ ही बैक्टीरिया को मारता है। इसे डॉक्टर के निर्देशानुसार प्रभावित क्षेत्र पर पतली परत में लगाएं, आमतौर पर दिन में एक या दो बार। इसे चेहरे, बगल या जांघों पर बिना डॉक्टर की सलाह के न लगाएं। इसे 2 सप्ताह से अधिक समय तक उपयोग न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, सूखापन और लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं, और रक्त वाहिकाएं दिखाई दे सकती हैं। कभी-कभी यह शरीर में अवशोषित होकर रक्त शर्करा और रक्तचाप को प्रभावित कर सकती है। यदि आपको गंभीर जलन, छाले, या सूजन हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के बताए अनुसार ही करें। प्रभावित क्षेत्र पर पतली परत लगाएं और हल्के से मलें। आंखों, नाक, मुंह और अन्य श्लेष्मा झिल्ली से संपर्क से बचें। बिना डॉक्टर की सलाह के चेहरे, बगल या जांघों पर न लगाएं। 2 सप्ताह से अधिक समय तक उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 sterk-fd cream Uses & Benefits
[{"condition":"Infected eczema","description":"This medicine is used to reduce inflammation and itching associated with eczema while simultaneously treating bacterial infection that may have developed in the affected skin.","evidence":"Well-established"},{"condition":"Infected dermatitis","description":"It helps control the inflammatory component of dermatitis and eradicates susceptible bacteria causing secondary infection.","evidence":"Well-established"},{"condition":"Infected psoriasis","description":"This medicine can be prescribed for short-term management of psoriasis plaques that have become infected, reducing scaling and bacterial load.","evidence":"Established"},{"condition":"Secondary infected dermatoses","description":"It is used for various skin conditions where inflammation is complicated by bacterial infection, providing both anti-inflammatory and antibacterial effects.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Infected insect bites","description":"Sometimes prescribed off-label to reduce inflammation and prevent infection from scratching insect bites.","evidence":"Limited"},{"condition":"Infected minor burns","description":"May be used off-label for small, superficial burns that show signs of infection, but only under medical supervision.","evidence":"Limited"}]
Primary treatment for: Infected inflammatory skin conditions (e.g., infected eczema, dermatitis, psoriasis)
Also treats: Bacterial skin infections, Dermatitis, Eczema, Psoriasis
📋 Drug Information
| Generic Name(s) | Clobetasol (0.05% w/w) + Fusidic Acid (2% w/w) |
| Brand Name | sterk-fd cream |
| Manufacturer | Solace Biotech Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Do not freeze. Keep the tube tightly closed when not in use. Protect from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise specified on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a super-potent corticosteroid and a topical antibiotic. Clobetasol propionate works by binding to glucocorticoid receptors inside skin cells. This binding activates anti-inflammatory proteins and suppresses pro-inflammatory signals, leading to a reduction in redness, swelling, itching, and scaling. Fusidic acid works by inhibiting bacterial protein synthesis. It binds to elongation factor G (EF-G) on the bacterial ribosome, preventing the translocation step necessary for protein production. This stops bacteria from growing and allows the body's immune system to clear the infection. The combination ensures that both inflammation and infection are addressed simultaneously.
Mechanism Steps
💡 How to Take sterk-fd cream
Strength: Topical cream containing clobetasol propionate 0.05% w/w and fusidic acid 2% w/w.
Dosage Information
| Adult Dosage | Apply a thin film of this medicine to the affected area(s) once or twice daily, as directed by your doctor. The frequency and duration of treatment depend on the condition being treated and its severity. For most conditions, treatment should not exceed 2 weeks without medical reassessment. Do not use more than 50 grams per week. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 1 year of age. In older children, use with caution and for short periods only, as they are more susceptible to systemic corticosteroid effects. |
| Elderly Dosage | Elderly patients may be more susceptible to the side effects of topical corticosteroids, especially skin thinning and systemic effects. Use the lowest effective dose for the shortest duration possible. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dosage adjustment is required for renal impairment when used topically, as systemic absorption is minimal. However, if large areas are treated or if the patient has severe renal impairment, use with caution and monitor for systemic effects. |
| Hepatic Impairment | No specific dosage adjustment is required for hepatic impairment when used topically. However, if significant systemic absorption occurs, use with caution in patients with severe hepatic impairment, as corticosteroids are metabolized in the liver. |
| Maximum Daily Dose | The maximum recommended dose is application to affected areas twice daily, not exceeding 50 grams of cream per week. Do not exceed the prescribed frequency or duration. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sterk-fd cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Ritonavir | Major | |
| Furosemide | Moderate | |
| Insulin | Moderate | |
| Metformin | Moderate | |
| Warfarin | Moderate | |
| NSAIDs | Minor | |
| Other topical steroids | Major | |
| Live vaccines | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Other topical corticosteroids
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Antidiabetic agents
🍷 Alcohol Interaction
No known direct interaction between this topical medicine and alcohol. However, alcohol may worsen certain skin conditions and can affect liver enzymes that metabolize corticosteroids if significant systemic absorption occurs. It is advisable to limit alcohol consumption while using this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to clobetasol, fusidic acid, or any component of the formulation.","Untreated bacterial skin infections other than those caused by susceptible organisms.","Viral skin infections (e.g., herpes simplex, chickenpox).","Fungal skin infections (e.g., tinea, candidiasis).","Parasitic skin infections (e.g., scabies).","Acne vulgaris, rosacea, and perioral dermatitis.","Use on the face, groin, or axillae unless specifically directed by a physician.","Use in children under 1 year of age.","Ophthalmic use."]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas of the body or for prolonged periods without medical supervision.","Do not use with occlusive dressings unless directed by a doctor.","If irritation or sensitization develops, discontinue use and consult a doctor.","Prolonged use may lead to skin atrophy, striae, and telangiectasia.","Systemic absorption may occur, especially with prolonged use or on broken skin, and may cause reversible HPA axis suppression.","Use with caution in patients with a history of diabetes, hypertension, or osteoporosis.","Do not use in children for longer than 5 days without medical advice.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether clobetasol or fusidic acid are excreted in human breast milk after topical application. However, systemic absorption is low. To minimize infant exposure, do not apply the cream to the breast area, and avoid applying to large areas or using occlusive dressings while breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose from topical application is unlikely. If excessive amounts are applied or ingested, seek medical attention immediately. Symptoms of overdose may include signs of systemic corticosteroid excess such as nausea, vomiting, weakness, and electrolyte imbalances. Treatment is supportive and symptomatic. In case of accidental ingestion, contact a poison control center or emergency room.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Use this medicine exactly as prescribed by your doctor. Apply a thin film to the affected area only, and gently rub it in. Do not cover the treated area with airtight dressings unless your doctor tells you to, as this can increase absorption and side effects. Wash your hands thoroughly before and after applying the cream, unless your hands are the treated area. Avoid contact with your eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use this medicine on the face, underarms, or groin area unless specifically instructed by your doctor. Do not use it for longer than the prescribed duration, and do not use it on large areas of the body without medical supervision. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before using this medicine. Do not use this medicine to treat any condition other than the one it was prescribed for. Keep this medicine out of the reach of children. Do not share this medicine with others, even if they have similar symptoms. If your condition does not improve within the expected time frame, or if it worsens, contact your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the side effects of topical corticosteroids, particularly skin thinning, easy bruising, and systemic effects such as hyperglycemia and hypertension. Use the lowest effective dose for the shortest duration possible. Monitor for signs of adrenal suppression if used extensively.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Avoid using super-potent corticosteroids like clobetasol, especially in the first trimester. Consider alternative treatments if possible.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before using this medicine on or near the surgical site. It may interfere with wound healing or increase the risk of infection. Do not apply to open wounds or surgical incisions unless specifically directed.
🦷 Dental Procedures
This medicine is applied to the skin and is not expected to affect dental procedures. However, inform your dentist if you are using it, especially if you have a history of corticosteroid use, as it may affect your overall health status.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while using this medicine. However, if you sweat heavily, gently clean the treated area and reapply the cream if necessary, as sweat may reduce its effectiveness. Avoid activities that cause excessive friction or rubbing on the treated area. If you swim, apply the cream after swimming and drying off, as chlorine and water may wash it away.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to work or drive. However, if you experience any dizziness or visual changes, avoid driving or operating heavy machinery until you feel normal. The cream may leave a greasy residue, so you may want to apply it when you are not immediately going out. It does not cause drowsiness.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your condition worsens, if you develop severe irritation or an allergic reaction, or if you have used it for the maximum prescribed duration (usually 2 weeks) without improvement. Do not stop abruptly if you have been using it for a long time without consulting your doctor, as this may cause a flare-up. Always follow your doctor's instructions on when to stop.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to skin thinning, stretch marks, telangiectasia, and increased hair growth. It can also cause systemic effects such as adrenal suppression, Cushing's syndrome, and hyperglycemia, especially if used on large areas or with occlusive dressings. To minimize risks, use the lowest effective dose for the shortest duration possible. Regular monitoring by a doctor is recommended if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Regular use of emollients can help repair the skin barrier and reduce the need for topical steroids.
Evidence: Well-establishedNon-steroidal anti-inflammatory creams that can be used for eczema and dermatitis, especially on sensitive areas.
Evidence: Well-establishedFor widespread bacterial infections, oral antibiotics may be needed instead of or in addition to topical antibiotics.
Evidence: Well-establishedControlled exposure to ultraviolet light can help manage conditions like psoriasis and eczema.
Evidence: Established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions between this topical medicine and vaccines are known. However, if you are using large amounts of this medicine and have systemic absorption, live vaccines may be less effective. Consult your doctor before receiving any live vaccine while using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep the tube tightly closed when not in use
❌ DON'T
Do not leave the cap off
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom
✅ DO
Keep out of reach of children
❌ DON'T
Do not transfer to another container
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are traveling to a different time zone, continue applying the cream at your usual times; topical application does not require strict time zone adjustment. Check customs regulations for carrying prescription medicines to your destination. Keep the tube in your carry-on luggage if you need it during the flight, but ensure it complies with liquid restrictions.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to notice improvement in itching and redness within a few days. The infection should begin to clear within 2-3 days. If there is no improvement after 1 week, consult your doctor.
A: No, this medicine is not for acne and can actually worsen it. It is contraindicated in acne vulgaris.
A: No, unless specifically directed by your doctor. The face has thinner skin and is more susceptible to side effects like thinning and stretch marks.
A: If you remember within a short time, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Consult your doctor before use. Topical corticosteroids should be used during pregnancy only if clearly needed. Avoid using on large areas or for prolonged periods.
🤔 Common Patient Concerns
🔄 Substitutes for sterk-fd cream
View AllAlternative brands with exact same active ingredient:
-
clobetagen f creamAlkem Laboratories Ltd ₹47.00 82% CHEAPER
-
paedisone mf creamPraise Pharma ₹93.75 64.2% CHEAPER
-
dicfu-c creamNidus Pharma Pvt Ltd ₹98.44 62.4% CHEAPER
-
clobiderm-f creamGary Pharmaceuticals Pvt Ltd ₹100.55 61.6% CHEAPER
-
clonova f creamRhine Biogenics Pvt Ltd ₹103.13 60.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This medicine is only for specific infected inflammatory skin conditions. It can worsen acne, rosacea, and fungal infections. - Myth: More cream means faster healing.
Fact: Applying more than a thin film does not speed up healing and increases the risk of side effects. - Myth: It is safe to use on the face.
Fact: This medicine should not be used on the face unless specifically directed by a doctor, as it can cause skin thinning and other side effects. - Myth: You can stop using it as soon as the skin looks better.
Fact: You should complete the prescribed course to ensure the infection is fully cleared and to prevent recurrence. - Myth: This cream is a cosmetic product.
Fact: This is a prescription medicine with potent active ingredients and should only be used under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Clobetasol + Fusidic Acid cream (generic versions may be available)