statum b cream - Betamethasone (0.05% w/w) + Clotrimazole (1% w/w) medicine

Betam NC Cream: Complete Guide to Uses, Side Effects, and Safety

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🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe burning, blistering, or peeling of the skin.
  • Signs of allergic reaction: rash, swelling of face, lips, or throat, difficulty breathing.
  • Increased redness, pus, or pain suggesting a secondary infection.
  • No improvement after 1 week of use.
  • Skin thinning, stretch marks, or unusual hair growth.
  • Vision changes if cream accidentally gets into eyes.

If experiencing severe symptoms, call emergency services immediately.

What is statum b cream used for?

This medicine is a topical cream containing betamethasone (a steroid) and clotrimazole (an antifungal). It treats fungal skin infections that have inflammation, reducing itching and redness while killing the fungus.

  • Generic Name: Betamethasone (0.05% w/w) + Clotrimazole (1% w/w)
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 statum b cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें बीटामेथासोन और क्लोट्रिमाज़ोल होते हैं। यह फंगल संक्रमण और सूजन दोनों का इलाज करती है। यह खुजली, लालिमा और सूजन को कम करती है और फंगस को मारती है। इसका उपयोग त्वचा के फंगल संक्रमण जैसे दाद, खाज-खुजली के लिए किया जाता है। इसे डॉक्टर के निर्देशानुसार ही लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में जलन, खुजली, या लालिमा शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, त्वचा का पतला होना, या संक्रमण हो सकता है। यदि कोई गंभीर समस्या हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस क्रीम को केवल प्रभावित हिस्से पर पतली परत में लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली से बचें। डॉक्टर की सलाह के बिना लंबे समय तक उपयोग न करें। बच्चों की पहुंच से दूर रखें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 statum b cream Uses & Benefits

[{"condition":"Fungal skin infections with inflammation","description":"Used to treat conditions like tinea corporis, tinea cruris, and tinea pedis when accompanied by significant inflammation and itching.","evidence":"Well-established"},{"condition":"Candidal skin infections with inflammation","description":"Effective for cutaneous candidiasis that has an inflammatory component.","evidence":"Well-established"},{"condition":"Eczema with suspected fungal infection","description":"May be used when eczema is complicated by a fungal infection.","evidence":"Limited"}]

Off-label uses: [{"condition":"Seborrheic dermatitis with fungal involvement","description":"Sometimes prescribed off-label when Malassezia yeast is suspected.","evidence":"Limited"}]

Primary treatment for: Fungal skin infections with inflammation

Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Cutaneous candidiasis

📋 Drug Information

Generic Name(s)Betamethasone (0.05% w/w) + Clotrimazole (1% w/w)
Brand Namestatum b cream
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore below 30°C in a dry place. Do not freeze. Keep the tube tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer only to the affected area and avoid normal skin.
2
Do not use this cream for more than 2 weeks without medical advice.
3
Wash your hands after applying unless your hands are being treated.
4
Avoid using on the face, groin, or underarms unless specifically prescribed.
5
If symptoms do not improve within 1 week, consult your doctor.
6
Do not share this cream with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy, red rash with defined edges
This medicine is commonly prescribed for fungal infections with inflammation.
Likely Use
❌
Dry, scaly skin without itching
This medicine is not for simple dry skin.
Not Primary
❌
Painful, pus-filled lesions
This may indicate a bacterial infection; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBetamethasone and clotrimazole are absorbed through intact skin to a limited extent. Systemic absorption can increase with prolonged use, use on large surface areas, or use under occlusive dressings.
DistributionBetamethasone is distributed throughout the body, with a high degree of protein binding. Clotrimazole distributes into tissues, but systemic distribution after topical application is minimal.
Protein BindingBetamethasone is approximately 60-70% bound to plasma proteins. Clotrimazole is highly protein-bound (approximately 90%).
MetabolismBetamethasone is metabolized in the liver, primarily by CYP3A4. Clotrimazole is metabolized in the liver and may inhibit CYP3A4 and CYP2C9.
Half-LifeBetamethasone: approximately 3-5 hours. Clotrimazole: approximately 2 hours after systemic absorption.
ExcretionBetamethasone and its metabolites are excreted primarily in urine. Clotrimazole metabolites are excreted in bile and urine.
BioavailabilityTopical bioavailability is low but variable; systemic absorption is minimal when used as directed on intact skin.
Onset of ActionRelief of itching and inflammation may begin within hours to days. Antifungal effects typically become noticeable within a few days to a week.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe anti-inflammatory effect lasts several hours; antifungal effect persists with regular application.

How It Works

Betamethasone is a corticosteroid that binds to glucocorticoid receptors in the skin, reducing the production of inflammatory mediators and suppressing immune responses, which decreases redness, swelling, and itching. Clotrimazole is an imidazole antifungal that inhibits the synthesis of ergosterol, a key component of fungal cell membranes, leading to increased membrane permeability and fungal cell death. Together, they address both inflammation and fungal infection.

Mechanism Steps

1
Betamethasone binds to glucocorticoid receptors: Betamethasone enters skin cells and binds to cytoplasmic glucocorticoid receptors, which then translocate to the nucleus and modulate gene transcription.
2
Suppression of inflammatory mediators: This binding reduces the production of pro-inflammatory cytokines, prostaglandins, and leukotrienes, leading to decreased redness, swelling, and itching.
3
Clotrimazole inhibits ergosterol synthesis: Clotrimazole inhibits the fungal enzyme lanosterol 14α-demethylase, blocking the conversion of lanosterol to ergosterol, a vital component of fungal cell membranes.
4
Fungal cell membrane damage: The lack of ergosterol and accumulation of toxic sterol precursors increase membrane permeability, causing leakage of cellular contents and fungal cell death.

💡 How to Take statum b cream

Strength: Cream containing betamethasone 0.05% w/w and clotrimazole 1% w/w.

1Wash your hands before and after applying the cream.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected skin.
4Gently rub it in until it disappears.
5Do not cover the area with bandages unless instructed.
6Avoid contact with eyes, mouth, and other mucous membranes.

Dosage Information

Adult DosageApply a thin layer to the affected area and gently rub it in, usually once or twice daily, or as directed by your doctor. The duration of treatment depends on the condition and your response. Do not use for longer than prescribed. Dose must be individualized by a qualified clinician based on indication, age, and severity of the condition.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to topical corticosteroid side effects. Use with caution and for the shortest duration necessary.
Renal ImpairmentNo dosage adjustment is required for topical use in renal impairment.
Hepatic ImpairmentNo dosage adjustment is required for topical use in hepatic impairment.
Maximum Daily DoseNot established from the available information. Use only as prescribed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of statum b cream

✅ Common Side Effects

Application site burning or stinging (Common (1-10%))
Usually resolves with continued use. If severe, stop and consult your doctor.
Itching (Common (1-10%))
May be due to the condition or the cream. If it worsens, consult your doctor.
Redness or rash (Common (1-10%))
Monitor. If it spreads or becomes severe, stop and seek medical advice.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Skin atrophy (thinning) (Uncommon (0.1-1%))
Avoid prolonged use. Consult a doctor if skin thinning occurs.
Secondary infection (Uncommon (0.1-1%))
Report any signs of new infection (increased redness, pus) to your doctor.

⚠️ Rare Side Effects

Stretch marks (striae)
Consult a dermatologist if concerned.
Increased hair growth
Usually reversible after stopping. Consult your doctor.
Hypopigmentation
Consult a dermatologist if skin color changes occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole (oral) Major
Warfarin Moderate
Ritonavir Major

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • Other topical corticosteroids
  • Warfarin

🍷 Alcohol Interaction

No known interaction between this topical medicine and alcohol. However, alcohol may worsen certain skin conditions. Consult your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to betamethasone, clotrimazole, or any component of the formulation.","Untreated bacterial or viral skin infections (e.g., herpes simplex, vaccinia, varicella).","Acne vulgaris, rosacea, perioral dermatitis.","Use on the face, groin, or axillae unless directed by a doctor.","Ophthalmic use."]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes.","Do not use on large areas or for prolonged periods unless directed.","Do not use under occlusive dressings unless instructed.","If irritation or sensitization occurs, discontinue use and consult a doctor.","Use in children may increase risk of systemic effects; consult a pediatrician.","Do not use for diaper dermatitis unless specifically prescribed."]

🤱 Lactation Safety

It is not known whether betamethasone or clotrimazole are excreted in human milk after topical application. Caution is advised when used by breastfeeding mothers. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Topical overdose is unlikely. If accidental ingestion occurs, seek medical attention. Prolonged excessive use may lead to systemic corticosteroid effects; manage symptomatically and consult a doctor.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Use this medicine exactly as prescribed by your doctor. Apply a thin layer to the affected area and gently rub it in. Wash your hands before and after application unless your hands are the treated area. Avoid contact with eyes, mouth, and other mucous membranes. Do not cover the treated area with bandages or dressings unless instructed. Do not use on large areas of the body or for longer than prescribed. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not use this medicine for any other skin condition without medical advice.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more prone to skin thinning and other corticosteroid side effects. Use with caution and for the shortest duration necessary.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Topical corticosteroids should be used with caution during pregnancy.

🏥 Post-Surgery Considerations

Consult your doctor before applying this cream to surgical wounds, as it may delay healing and increase infection risk.

🦷 Dental Procedures

No specific considerations for dental procedures, as this is a topical skin cream.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or footwear.
😴
Wear loose-fitting, breathable clothing.
💧
Avoid scratching the affected area to prevent spread.
🧘
Complete the full course of treatment even if symptoms improve.

🏋️ Exercise Considerations

No specific exercise restrictions, but avoid activities that cause excessive sweating or friction on the treated area until it heals.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Stay hydrated.
Limit sugary and processed foods, which may worsen inflammation.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to work or drive. However, if you experience application site reactions, avoid activities that may irritate the skin.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms worsen, if you develop new symptoms, or if you have used it for the prescribed duration without improvement. Do not stop abruptly if you have been using it for a long time without medical advice.

📅 Long-Term Use Effects

Prolonged use of this medicine can lead to skin thinning, stretch marks, and increased risk of secondary infections. It may also cause systemic corticosteroid effects if used on large areas for extended periods. Use only as prescribed and for the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungal alone

If inflammation is mild, a plain antifungal cream may be sufficient.

Evidence: Well-established
Oral antifungal

For extensive or resistant infections, oral antifungals may be needed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. However, live vaccines should be avoided if you are using high-dose systemic corticosteroids, but topical use is unlikely to affect vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label. Keep it in your carry-on luggage if traveling by air. Store at room temperature and avoid extreme heat or cold. If traveling across time zones, continue your regular application schedule. Declare it if required by customs. Bring enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with an itchy, red rash in the groin area.
He was diagnosed with tinea cruris with inflammation. He applied this medicine twice daily as prescribed. After 5 days, itching and redness reduced significantly. He completed the full course as directed.
💡 Lesson: Consistent application and completing the prescribed course helps clear the infection and prevents recurrence.
👤 A 50-year-old woman with a fungal infection on her feet and severe itching.
She used this cream once daily for 2 weeks. The itching subsided within a few days, and the rash cleared gradually. She was advised to keep her feet dry and avoid sharing footwear.
💡 Lesson: Good hygiene practices along with medication improve outcomes and prevent reinfection.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Itching and redness may start improving within a few days. The fungal infection typically clears within 1-2 weeks, but complete treatment may take longer.

Q: Can I stop using it when symptoms improve?

A: No, complete the full course as prescribed to prevent the infection from returning.

Q: Is it safe to use on children?

A: Consult a pediatrician before using on children, as they may be more susceptible to side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this cream for a long time?
  • Will it thin my skin?
  • Can I use it on my face?
  • Is it safe during pregnancy?
  • What if I forget to apply it?
  • Can I use it with other creams?

🔄 Substitutes for statum b cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This cream can be used for any skin rash.
    Fact: It is only for fungal infections with inflammation. Using it for other rashes can worsen the condition.
  • Myth: More cream means faster healing.
    Fact: Applying more than prescribed can increase side effects without speeding up healing.
  • Myth: It is safe to use for months.
    Fact: Prolonged use can cause skin thinning and other side effects. Use only as long as directed.

🔄 Alternative Options

Generic Alternatives

  • Betamethasone + Clotrimazole cream (generic)

Brand Alternatives

  • Betam NC Cream
  • Other brands containing betamethasone and clotrimazole

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Betamethasone 0.05% + Clotrimazole 1%","use":"Fungal infections with inflammation","prescription":true},{"medicine":"Clotrimazole cream","composition":"Clotrimazole 1%","use":"Fungal infections only","prescription":false},{"medicine":"Betamethasone cream","composition":"Betamethasone 0.05%","use":"Inflammatory skin conditions","prescription":true}]

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