Stanrox Ds 800mg/160mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
- Sore throat with fever
- Widespread skin rash with blisters or peeling
If experiencing severe symptoms, call emergency services immediately.
What is stanrox ds 800mg/160mg tablet used for?
This medicine is a prescription antibiotic combining sulfamethopyrazine and trimethoprim. It treats bacterial infections by blocking two steps in the bacteria's folate pathway. It is not effective against viral infections like the common cold.
- Generic Name: Sulfamethopyrazine (800mg) + Trimethoprim (160mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 stanrox ds 800mg/160mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक प्रिस्क्रिप्शन एंटीबायोटिक है जिसमें सल्फामेथोपाइराज़ीन (800 मिलीग्राम) और ट्राइमेथोप्रिम (160 मिलीग्राम) शामिल हैं। यह मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, और कुछ पेट के संक्रमणों के इलाज के लिए इस्तेमाल की जाती है। यह वायरल बीमारियों जैसे सर्दी-जुकाम या फ्लू पर असर नहीं करती। इस दवा को डॉक्टर की सलाह के बिना न लें और कोर्स पूरा करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, और भूख में कमी शामिल हैं। कुछ लोगों को त्वचा पर चकत्ते, खुजली, या धूप से एलर्जी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें त्वचा की गंभीर प्रतिक्रियाएं, रक्त विकार, लीवर की समस्या, और किडनी की समस्या शामिल हो सकती हैं। अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, या त्वचा पर फफोले दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। दिन भर पर्याप्त पानी पिएं। कोर्स पूरा करें, बीच में न छोड़ें। धूप में जाने से बचें और सनस्क्रीन का इस्तेमाल करें। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको सल्फा से एलर्जी है, तो डॉक्टर को बताएं। शराब न पिएं। दवा को ठंडी और सूखी जगह पर रखें।
💊 stanrox ds 800mg/160mg tablet Uses & Benefits
[{"condition":"Urinary tract infections","description":"Used to treat uncomplicated and complicated urinary tract infections caused by susceptible bacteria such as Escherichia coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Prescribed for acute exacerbations of chronic bronchitis and some cases of pneumonia caused by susceptible organisms.","evidence":"Established"},{"condition":"Gastrointestinal infections","description":"May be used for certain bacterial diarrheas and enteric infections when culture and sensitivity support its use.","evidence":"Limited"},{"condition":"Skin and soft tissue infections","description":"Sometimes used for uncomplicated skin infections caused by susceptible bacteria, though other agents are often preferred.","evidence":"Limited"}]
Off-label uses: [{"condition":"Pneumocystis jirovecii pneumonia prophylaxis","description":"Trimethoprim-sulfamethoxazole combinations are used for prophylaxis in immunocompromised patients, but sulfamethopyrazine-trimethoprim is not the standard formulation for this purpose.","evidence":"Limited"},{"condition":"Toxoplasmosis prophylaxis","description":"Sometimes considered in immunocompromised individuals, but not a first-line option and not established for this specific combination.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Respiratory tract infections, Gastrointestinal infections, Skin infections
📋 Drug Information
| Generic Name(s) | Sulfamethopyrazine (800mg) + Trimethoprim (160mg) |
| Brand Name | stanrox ds 800mg/160mg tablet |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight, moisture, and heat. Do not refrigerate unless specified on the label. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise stated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking two consecutive steps in the bacterial folate synthesis pathway. Sulfamethopyrazine competes with para-aminobenzoic acid (PABA) to inhibit dihydropteroate synthase, preventing the formation of dihydrofolic acid. Trimethoprim then inhibits dihydrofolate reductase, blocking the conversion of dihydrofolic acid to tetrahydrofolic acid. Because bacteria cannot use preformed folate from their environment, this sequential blockade stops them from making the nucleic acids and proteins they need to survive and multiply. Human cells obtain folate from the diet and are much less affected, which gives this combination selective toxicity against bacteria.
Mechanism Steps
💡 How to Take stanrox ds 800mg/160mg tablet
Strength: Immediate-release tablet containing sulfamethopyrazine 800 mg and trimethoprim 160 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, depending on the type and severity of the infection. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and clinical response. Do not self-adjust the dose. Always complete the full course as prescribed, even if symptoms improve. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially to blood disorders, kidney problems, and hypoglycemia. Dose adjustments may be necessary based on renal function. Close monitoring of blood counts, kidney function, and blood sugar is recommended. Consult a clinician for individualized dosing. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance between 15 and 30 mL/min, the dose should be reduced or the dosing interval extended. This medicine is contraindicated in severe renal impairment (creatinine clearance <15 mL/min) unless the benefits outweigh the risks and close monitoring is available. Consult a clinician for specific dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. This medicine is contraindicated in severe hepatic impairment. Monitor liver function tests regularly. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Dosing must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of stanrox ds 800mg/160mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| ACE inhibitors/ARBs | Major | |
| Potassium-sparing diuretics | Major | |
| Phenytoin | Major | |
| Rifampicin | Moderate | |
| Amantadine | Moderate | |
| Digoxin | Moderate | |
| Sulfonylureas | Moderate | |
| Thiazide diuretics | Moderate |
🚨 Major Interactions
- Warfarin
- Methotrexate
- ACE inhibitors or angiotensin receptor blockers (ARBs)
- Potassium-sparing diuretics (spironolactone, amiloride)
- Phenytoin
⚡ Moderate Interactions
- Rifampicin
- Amantadine
- Digoxin
- Oral hypoglycemics (sulfonylureas)
- Thiazide diuretics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of stomach upset, liver irritation, and may worsen side effects such as nausea and dizziness. It can also interfere with your body's ability to fight the infection and may increase the risk of low blood sugar.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to sulfonamides or trimethoprim","History of drug-induced immune thrombocytopenia with trimethoprim","Severe hepatic impairment","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Serious skin reactions: Stop immediately if rash, blisters, or peeling skin occur.","Blood disorders: Report unusual bruising, bleeding, or sore throat with fever.","Hypoglycemia: Monitor blood sugar if you have diabetes or are elderly.","Hyperkalemia: Monitor potassium if you take ACE inhibitors, ARBs, or potassium-sparing diuretics.","Crystalluria: Drink plenty of fluids to prevent crystal formation in urine.","Photosensitivity: Avoid prolonged sun exposure and use sunscreen.","Folate deficiency: May cause megaloblastic anemia with prolonged use.","Superinfection: May lead to overgrowth of non-susceptible organisms, including Clostridioides difficile."]
🤱 Lactation Safety
This medicine passes into breast milk. It is generally not recommended during breastfeeding, especially for premature infants, infants with jaundice, or those with glucose-6-phosphate dehydrogenase deficiency. Consult your doctor to weigh the benefits and risks and to consider alternative antibiotics.
💊 Overdose Management
Overdose of this medicine can cause nausea, vomiting, dizziness, headache, and blood disorders. In severe cases, it may lead to bone marrow suppression, liver toxicity, or kidney damage. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal if taken recently, intravenous fluids, and monitoring of blood counts, liver, and kidney function. There is no specific antidote. Folinic acid may be considered for trimethoprim toxicity.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, with a full glass of water, and preferably with food to reduce stomach upset. Drink plenty of fluids throughout the day to help prevent crystals from forming in the urine. Do not skip doses or stop the course early, even if you feel better after a few days. Avoid prolonged exposure to sunlight and use sunscreen, because this medicine can make your skin more sensitive to UV rays. Do not take this medicine if you are allergic to sulfa drugs or trimethoprim. Tell your doctor about all other medicines you take, especially blood thinners, diabetes medicines, and water pills. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before using this medicine. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of side effects from this medicine, including severe skin reactions, blood disorders, kidney problems, and hypoglycemia. Dose adjustments may be needed based on kidney function. Close monitoring of blood counts, kidney function, and blood sugar is recommended. Avoid concurrent use with other medications that affect potassium or blood sugar.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy, especially in the first trimester and near term. Your doctor may prescribe a safer alternative antibiotic if you have a bacterial infection. Use effective contraception while taking this medicine if you are of childbearing age.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery. Your doctor may advise you to stop the medicine before surgery or adjust the dose. Do not stop without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with other medications or affect healing. Your dentist may recommend postponing non-urgent procedures until you complete the course. Maintain good oral hygiene to prevent infection.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild to moderate exercise is generally safe while taking this medicine, but listen to your body. If you feel dizzy, weak, or short of breath, stop and rest. Avoid strenuous exercise if you have a fever or are dehydrated. Stay well hydrated during workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, headache, or fatigue in some people. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Most people can continue their normal daily activities, but take it easy if you have a fever or feel unwell. Inform your employer if you need to take sick leave.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full prescribed course, unless your doctor tells you otherwise. If you experience a severe allergic reaction, severe skin rash, difficulty breathing, or any serious side effect, stop immediately and seek medical help. Do not stop early just because you feel better, as this can lead to relapse and resistance.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to folate deficiency, megaloblastic anemia, and increased risk of resistant infections. It may also cause bone marrow suppression, liver toxicity, and kidney problems. Regular monitoring of blood counts, liver function, and kidney function is recommended if prolonged therapy is necessary. Do not use this medicine for longer than prescribed without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water can help flush out bacteria in urinary tract infections.
Evidence: Well-establishedMay help prevent antibiotic-associated diarrhea, but consult your doctor before use.
Evidence: ModerateMay help prevent urinary tract infections, but not a treatment for active infection.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, if you are scheduled for a live vaccine, inform your doctor that you are taking an antibiotic. There is no need to delay vaccination unless you are acutely ill with fever.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from direct sunlight. If crossing time zones, continue your dosing schedule as close to the original times as possible. Check customs regulations for prescription medicines in your destination country. Carry enough supply for your entire trip plus extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but you must complete the full course as prescribed to fully clear the infection.
A: Yes, taking it with food or milk helps reduce stomach upset.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double dose.
A: This medicine is generally not recommended during pregnancy, especially in the first trimester and near term. Consult your doctor for safer alternatives.
A: It is best to avoid alcohol as it can worsen side effects and increase liver stress.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine is an antibiotic and does not work against viruses. It only treats bacterial infections. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent relapse and resistance. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with sulfa allergy, severe kidney or liver disease, G6PD deficiency, or during pregnancy. - Myth: Taking this medicine with alcohol is fine.
Fact: Alcohol can worsen side effects and should be avoided.
🔄 Alternative Options
Generic Alternatives
- Sulfamethopyrazine + Trimethoprim generic tablets
Brand Alternatives
- Stanrox DS 800mg/160mg Tablet