stanla-forte tablet - Clonazepam (0.5mg) + Escitalopram Oxalate (20mg) medicine

Dexanil Forte 0.5mg/20mg Tablet: Complete Medicine Guide

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🏭 Mabril Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor immediately if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination use is supported by clinical practice.
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Thoughts of harming yourself or others
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Irregular heartbeat or chest pain
  • Severe confusion or hallucinations
  • High fever with muscle rigidity and sweating
  • Yellowing of skin or eyes
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is stanla-forte tablet used for?

This medicine is a combination of clonazepam and escitalopram used to treat anxiety disorders, panic disorder, and depression with anxiety. It works by calming the brain and increasing serotonin levels. It is a prescription-only medicine and should be taken exactly as directed by your doctor.

  • Generic Name: Clonazepam (0.5mg) + Escitalopram Oxalate (20mg)
  • Manufacturer: Mabril Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 stanla-forte tablet के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोनाजेपम और एस्सिटालोप्राम का संयोजन है, जिसका उपयोग चिंता विकार, पैनिक डिसऑर्डर और अवसाद के इलाज के लिए किया जाता है। यह मस्तिष्क को शांत करने और सेरोटोनिन के स्तर को बढ़ाने में मदद करती है। यह केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर के निर्देशानुसार ही लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, थकान, मुँह सूखना, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, सांस लेने में कठिनाई, दिल की धड़कन अनियमित होना और सेरोटोनिन सिंड्रोम शामिल हैं। यदि आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। शराब और अन्य नींद लाने वाली दवाओं से बचें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। इस दवा को अचानक बंद न करें, इससे withdrawal symptoms हो सकते हैं। इसे ठंडी और सूखी जगह पर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 stanla-forte tablet Uses & Benefits

[{"condition":"Generalized anxiety disorder","description":"This combination helps reduce excessive worry, tension, and nervousness by combining the rapid calming effect of clonazepam with the longer-term anxiety-reducing effect of escitalopram.","evidence":"Well-established for the individual components; combination use is common in clinical practice."},{"condition":"Panic disorder","description":"Clonazepam provides quick relief from panic attacks, while escitalopram helps prevent future panic attacks over time.","evidence":"Well-established for the individual components; combination use is common in clinical practice."},{"condition":"Depression with anxiety","description":"Escitalopram treats the core symptoms of depression, and clonazepam helps manage prominent anxiety symptoms in the early weeks of treatment.","evidence":"Well-established for the individual components; combination use is common in clinical practice."}]

Off-label uses: [{"condition":"Social anxiety disorder","description":"Sometimes prescribed off-label when social anxiety is severe and disabling.","evidence":"Limited"},{"condition":"Insomnia associated with anxiety","description":"May be used off-label for short-term management of insomnia related to anxiety disorders.","evidence":"Limited"}]

Primary treatment for: Anxiety disorders

Also treats: Panic disorder, Depression with anxiety, Social anxiety disorder

📋 Drug Information

Generic Name(s)Clonazepam (0.5mg) + Escitalopram Oxalate (20mg)
Brand Namestanla-forte tablet
ManufacturerMabril Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent levels.
2
Do not stop this medicine abruptly; always consult your doctor for a gradual taper.
3
Avoid driving or operating heavy machinery until you know how this medicine affects you.
4
Inform your doctor if you experience increased anxiety, insomnia, or unusual thoughts.
5
Keep all follow-up appointments for monitoring of your condition and side effects.
6
Maintain a healthy lifestyle with regular sleep, balanced diet, and stress management techniques.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Excessive worry and tension
This medicine is commonly prescribed for anxiety disorders.
Likely Use
✅
Panic attacks
This medicine helps reduce the frequency and severity of panic attacks.
Likely Use
✅
Depressed mood
Escitalopram in this medicine treats depression.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClonazepam is well absorbed after oral administration, with a bioavailability of approximately 90%. Escitalopram is also well absorbed, with a bioavailability of about 80%. Food does not significantly affect the absorption of either component.
DistributionClonazepam is highly lipophilic and distributes widely into body tissues, including the brain. Escitalopram distributes throughout the body, with a volume of distribution of about 12 L/kg.
Protein BindingClonazepam is approximately 85% bound to plasma proteins. Escitalopram is about 56% bound to plasma proteins.
MetabolismClonazepam is metabolized in the liver primarily by cytochrome P450 enzymes, including CYP3A4, to inactive metabolites. Escitalopram is metabolized in the liver by CYP2C19 and CYP3A4 to less active metabolites.
Half-LifeThe elimination half-life of clonazepam is approximately 30 to 40 hours. The elimination half-life of escitalopram is approximately 27 to 32 hours.
ExcretionClonazepam is excreted mainly in the urine as inactive metabolites. Escitalopram is excreted in both urine and feces as metabolites and unchanged drug.
BioavailabilityClonazepam: approximately 90%. Escitalopram: approximately 80%.
Onset of ActionClonazepam begins to work within 30 to 60 minutes after oral administration. Escitalopram typically takes 1 to 2 weeks to show initial effects and 4 to 6 weeks for full therapeutic benefit.
Peak Plasma TimeClonazepam reaches peak plasma levels in 1 to 4 hours. Escitalopram reaches peak plasma levels in about 4 hours.
Duration of ActionClonazepam's anxiolytic effect lasts about 6 to 12 hours. Escitalopram provides continuous effect with once-daily dosing.

How It Works

This medicine combines two active ingredients with different mechanisms. Clonazepam enhances the inhibitory effect of gamma-aminobutyric acid at GABA-A receptors in the brain, leading to increased chloride channel opening and neuronal hyperpolarization, which produces calming, anxiolytic, and muscle-relaxant effects. Escitalopram oxalate selectively inhibits the reuptake of serotonin at the presynaptic serotonin transporter, increasing serotonin availability in the synaptic cleft, which over time helps regulate mood and reduce anxiety.

Mechanism Steps

1
Clonazepam binds to GABA-A receptors: Clonazepam binds to the benzodiazepine site on GABA-A receptors in the brain, enhancing the effect of the inhibitory neurotransmitter GABA.
2
Increased chloride channel opening: This binding increases the frequency of chloride channel opening, leading to hyperpolarization of neurons and reduced neuronal excitability.
3
Rapid anxiolytic effect: The result is a rapid reduction in anxiety, tension, and panic symptoms, along with sedation and muscle relaxation.
4
Escitalopram inhibits serotonin reuptake: Escitalopram blocks the serotonin transporter on presynaptic neurons, preventing the reuptake of serotonin from the synaptic cleft.
5
Increased serotonin availability: This leads to higher serotonin levels in the synapse, which over several weeks helps improve mood and reduce anxiety.

💡 How to Take stanla-forte tablet

Strength: Tablet containing clonazepam 0.5 mg and escitalopram oxalate 20 mg.

1Take the tablet by mouth with a glass of water.
2Swallow the tablet whole. Do not crush, chew, or break it.
3Take it at the same time each day to maintain consistent levels.
4You can take it with or without food, but taking it with food may reduce stomach upset.
5Do not take more than the prescribed dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once daily, preferably at the same time each day. The dose may be adjusted by your doctor based on your response and tolerability. Do not change the dose without consulting your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Regular monitoring for falls, confusion, and sedation is recommended.
Renal ImpairmentDose adjustment may be necessary in patients with severe renal impairment. Consult your doctor for personalized dosing.
Hepatic ImpairmentDose reduction is recommended in patients with mild to moderate hepatic impairment. This medicine is contraindicated in severe hepatic impairment.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (clonazepam 0.5 mg + escitalopram 20 mg). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases sedation and impairs motor skills.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of stanla-forte tablet

✅ Common Side Effects

Drowsiness (Common (10-30%))
Avoid driving or operating machinery until you know how this medicine affects you. If drowsiness persists, consult your doctor.
Dizziness (Common (10-20%))
Rise slowly from sitting or lying positions. If dizziness is severe or persistent, contact your doctor.
Dry mouth (Common (10-20%))
Sip water frequently, chew sugar-free gum, or use saliva substitutes. Consult your doctor if it becomes bothersome.
Nausea (Common (10-15%))
Take the tablet with food. If nausea persists or worsens, inform your doctor.
Fatigue (Common (10-15%))
Ensure adequate rest. If fatigue interferes with daily activities, consult your doctor.

🚨 Serious Side Effects

Serotonin syndrome (Rare (<0.1%))
Seek immediate medical attention if you experience agitation, hallucinations, rapid heartbeat, fever, sweating, muscle stiffness, or confusion.
Severe allergic reaction (Rare (<0.1%))
Stop the medicine and seek emergency help if you notice rash, itching, swelling of the face, lips, tongue, or throat, or difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you feel palpitations, chest pain, or shortness of breath.
Suicidal thoughts (Uncommon (0.1-1%))
Seek immediate help if you have thoughts of harming yourself. This is more common in young adults during the first few weeks of treatment.

⚠️ Rare Side Effects

Blood disorders (e.g., leukopenia, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor promptly.
Liver problems
Seek medical attention if you notice yellowing of the skin or eyes, dark urine, or severe abdominal pain.
Hyponatremia (low sodium levels)
Inform your doctor if you experience confusion, headache, weakness, or difficulty concentrating.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Opioids Major
Ketoconazole Major
Omeprazole Moderate
Warfarin Moderate
Ibuprofen Moderate
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • MAO inhibitors
  • Other CNS depressants (e.g., opioids, alcohol, barbiturates)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • CYP2C19 inhibitors (e.g., omeprazole, fluoxetine)
  • NSAIDs (e.g., ibuprofen, aspirin)
  • Warfarin

🍷 Alcohol Interaction

Alcohol should be strictly avoided while taking this medicine. It can increase drowsiness, dizziness, and the risk of respiratory depression, and it can worsen anxiety and depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to clonazepam, escitalopram, or any component of the formulation","Concurrent use with MAO inhibitors","Severe liver disease","Narrow-angle glaucoma","Myasthenia gravis","Severe respiratory insufficiency","Sleep apnea syndrome","Pregnancy (unless clearly needed)"]

⚠️ Warnings & Precautions

["This medicine can cause drowsiness and dizziness. Do not drive or operate machinery until you know how it affects you.","Do not stop this medicine abruptly, as it can cause withdrawal symptoms.","Use with caution in elderly patients due to increased risk of falls and confusion.","Monitor for signs of serotonin syndrome, especially when used with other serotonergic drugs.","Avoid alcohol and other CNS depressants.","Inform your doctor if you have a history of substance abuse, as clonazepam has a potential for dependence.","Use with caution in patients with liver or kidney disease.","May increase the risk of suicidal thoughts in young adults; close monitoring is required."]

🤱 Lactation Safety

Clonazepam and escitalopram are excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor. Consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose can cause severe drowsiness, confusion, coma, respiratory depression, and cardiac arrest. Seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, gastric lavage, and monitoring of vital signs. Flumazenil may be used as an antidote for benzodiazepine overdose, but it should be used with caution.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Avoid alcohol and other central nervous system depressants because they can increase drowsiness and dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. Do not stop taking this medicine suddenly, as it can cause withdrawal symptoms such as anxiety, insomnia, and irritability. Keep all follow-up appointments and inform your doctor about any other medicines you are taking. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative effects of clonazepam and may experience increased drowsiness, confusion, and falls. Escitalopram can cause hyponatremia in the elderly. Start with a lower dose and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Both clonazepam and escitalopram may pose risks to the fetus. Your doctor may adjust or change your treatment plan.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It can interact with anesthetic agents and increase sedation. Your doctor may advise you to stop or adjust the dose before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It can interact with local anesthetics and sedatives used during dental procedures. Your dentist may need to adjust the treatment plan.

💚 Lifestyle Tips for Better Results

🏃
Maintain a regular sleep schedule to support mental health.
🥗
Engage in regular physical activity, such as walking or yoga, to reduce anxiety.
😴
Practice relaxation techniques like deep breathing and meditation.
💧
Avoid caffeine and nicotine, which can worsen anxiety.
🧘
Stay connected with friends and family for emotional support.
🌞
Keep a mood diary to track your progress and share with your doctor.

🏋️ Exercise Considerations

This medicine can cause drowsiness and dizziness, which may affect your coordination. Avoid high-risk activities like swimming, cycling, or using heavy machinery until you know how the medicine affects you. Light to moderate exercise is generally safe and beneficial.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed and high-sugar foods.
Stay well hydrated throughout the day.
Eat a balanced diet rich in fruits, vegetables, and whole grains.
Avoid alcohol and excessive caffeine.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves safety-sensitive tasks. With treatment, many people experience improved focus and productivity as anxiety and depression symptoms decrease.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor immediately. Your doctor will guide you on a gradual tapering schedule to avoid withdrawal symptoms.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance to clonazepam, requiring dose adjustments. There is a risk of dependence and withdrawal symptoms. Escitalopram may cause sexual dysfunction, weight changes, and emotional blunting in some patients. Regular monitoring by a doctor is essential to assess the ongoing need and to manage any side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cognitive behavioral therapy (CBT)

CBT is highly effective for anxiety and depression and can complement medication.

Evidence: Well-established
Mindfulness and meditation

These practices can help reduce anxiety and improve mood.

Evidence: Moderate
Regular exercise

Exercise has been shown to reduce symptoms of anxiety and depression.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Check local customs regulations regarding controlled substances before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with generalized anxiety disorder and depression
She was started on this medicine by her psychiatrist. Initially, she felt drowsy during the day, but this improved after a week. By the fourth week, her anxiety and mood had significantly improved. She emphasized the importance of not missing doses and keeping regular follow-ups.
💡 Lesson: Consistent use and patience are key. Initial side effects often subside, and full benefits may take several weeks.
👤 A 50-year-old man with panic disorder
He experienced frequent panic attacks that interfered with his work. After starting this medicine, the frequency of panic attacks decreased dramatically within two weeks. He also attended cognitive behavioral therapy, which helped him cope better.
💡 Lesson: Combining medication with therapy can provide better outcomes for panic disorder.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Clonazepam starts working within 30-60 minutes, providing rapid relief from anxiety. Escitalopram takes 1-2 weeks for initial effects and 4-6 weeks for full therapeutic benefit.

Q: Can I stop taking this medicine suddenly?

A: No, stopping suddenly can cause withdrawal symptoms such as anxiety, insomnia, and irritability. Always consult your doctor for a gradual taper.

Q: Is it safe to take this medicine during pregnancy?

A: The safety of this medicine during pregnancy is not well established. Consult your doctor immediately if you are pregnant or planning to become pregnant.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for stanla-forte tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a sleeping pill.
    Fact: This medicine is primarily used for anxiety and depression, though it can cause drowsiness as a side effect.
  • Myth: I can stop taking this medicine whenever I feel better.
    Fact: Stopping suddenly can cause withdrawal symptoms and relapse. Always consult your doctor before stopping.
  • Myth: This medicine is addictive for everyone.
    Fact: Clonazepam has a potential for dependence, but when used as prescribed and for a limited duration, the risk is manageable. Escitalopram is not addictive.

🔄 Alternative Options

Generic Alternatives

  • Clonazepam 0.5 mg + Escitalopram 20 mg tablet (generic)

Brand Alternatives

  • Dexanil Forte 0.5mg/20mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Clonazepam 0.5 mg + Escitalopram 20 mg","onset":"Rapid (clonazepam) + Delayed (escitalopram)","primary_use":"Anxiety with depression"},{"medicine":"Escitalopram 20 mg alone","composition":"Escitalopram 20 mg","onset":"Delayed (1-2 weeks)","primary_use":"Depression and anxiety"},{"medicine":"Clonazepam 0.5 mg alone","composition":"Clonazepam 0.5 mg","onset":"Rapid (30-60 minutes)","primary_use":"Anxiety and panic"}]

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