stancef o syrup - Cefixime (125mg) medicine

Cefixime 125mg Oral Syrup: Complete Medicine Guide

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🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain or cramps
  • Difficulty breathing or swelling of face, lips, or throat
  • Severe headache with visual changes
  • Decreased urine output
  • Yellowing of skin or eyes
  • Persistent high fever

If experiencing severe symptoms, call emergency services immediately.

What is stancef o syrup used for?

This medicine is a cephalosporin antibiotic syrup containing Cefixime 125mg per 5 mL. It treats bacterial infections of the ear, throat, sinuses, chest, urinary tract, and uncomplicated gonorrhea. It works by killing bacteria. Take as prescribed by your doctor.

  • Generic Name: Cefixime (125mg)
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 stancef o syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एक सेफलोस्पोरिन एंटीबायोटिक सिरप है जिसमें सेफिक्साइम 125mg प्रति 5 mL होता है। यह कान, गले, साइनस, छाती, मूत्र मार्ग के बैक्टीरियल संक्रमण और जटिलतारहित गोनोरिया के इलाज के लिए उपयोग की जाती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है। इसका उपयोग डॉक्टर के पर्चे के बिना न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, गंभीर दस्त और गुर्दे की समस्या शामिल हो सकती है। यदि आपको दाने, सूजन, सांस लेने में कठिनाई या लगातार गंभीर दस्त हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और न ही समय से पहले बंद करें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। दवा को मापने के लिए दिए गए चम्मच या सिरिंज का उपयोग करें। यदि आपको गुर्दे की समस्या, एलर्जी है या आप गर्भवती या स्तनपान करा रही हैं तो डॉक्टर को बताएं। इस दवा के साथ शराब न लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 stancef o syrup Uses & Benefits

[{"condition":"Ear infections (otitis media)","description":"This medicine is used to treat middle ear infections caused by susceptible bacteria such as Haemophilus influenzae and Streptococcus pneumoniae.","evidence":"Well-established"},{"condition":"Throat infections (pharyngitis/tonsillitis)","description":"It is effective against streptococcal throat infections when other antibiotics are not suitable.","evidence":"Well-established"},{"condition":"Sinusitis","description":"This medicine helps clear bacterial sinus infections, reducing facial pain and congestion.","evidence":"Well-established"},{"condition":"Bronchitis","description":"It is used for acute bacterial exacerbations of chronic bronchitis and other lower respiratory tract infections.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"This medicine treats uncomplicated urinary tract infections caused by susceptible organisms like Escherichia coli and Klebsiella pneumoniae.","evidence":"Well-established"},{"condition":"Uncomplicated gonorrhea","description":"A single dose of this medicine is used to treat uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used off-label for early Lyme disease in patients allergic to doxycycline, but evidence is limited.","evidence":"Limited"},{"condition":"Typhoid fever","description":"May be used off-label for typhoid fever in some regions, but resistance is common and other agents are preferred.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Otitis media, Pharyngitis, Sinusitis, Bronchitis, Urinary tract infections, Gonorrhea

📋 Drug Information

Generic Name(s)Cefixime (125mg)
Brand Namestancef o syrup
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationOral
StorageStore at room temperature (15-30°C). Protect from light and moisture. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always complete the full course of this medicine as prescribed, even if symptoms improve.
2
Shake the bottle well before each use to ensure uniform dosing.
3
Use the provided measuring device to avoid inaccurate dosing.
4
Take with food if it causes stomach upset.
5
Inform your doctor if you have kidney problems or are allergic to penicillins.
6
Do not share this medicine with others, even if they have similar symptoms.
7
Report any severe diarrhea or allergic reactions immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Ear pain
This medicine is commonly prescribed for ear infections.
Likely Use
✅
Sore throat
Used for bacterial pharyngitis.
Likely Use
❌
Fever
This medicine is not a primary fever reducer but may help if fever is due to bacterial infection.
Not Primary
✅
Cough
Used for bacterial bronchitis.
Likely Use
✅
Burning urination
Used for urinary tract infections.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract after oral administration. The exact bioavailability is not established from the available information, but it is reported to be approximately 40-50% in some sources. Food may slightly delay absorption but does not significantly reduce the overall amount absorbed.
DistributionThis medicine distributes into various body tissues and fluids, including the respiratory tract, urine, and bile. Protein binding is approximately 65%.
Protein BindingApproximately 65% bound to plasma proteins.
MetabolismThis medicine is not extensively metabolized. It undergoes minimal hepatic metabolism.
Half-LifeThe elimination half-life is approximately 3 to 4 hours in healthy adults with normal kidney function.
ExcretionThis medicine is primarily excreted unchanged in the urine. About 50% of an oral dose is excreted unchanged in the urine within 24 hours.
BioavailabilityThe oral bioavailability is approximately 40-50%.
Onset of ActionThe onset of action is typically within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimePeak plasma concentration is reached approximately 2 to 4 hours after oral administration.
Duration of ActionThe duration of action is approximately 12 to 24 hours, depending on the dose and susceptibility of the organism.

How It Works

This medicine works by binding to penicillin-binding proteins (PBPs) inside the bacterial cell wall. This binding inhibits the cross-linking of peptidoglycan chains, which are essential for cell wall strength. As a result, the bacterial cell wall becomes weak and the cell bursts, leading to bacterial death. This medicine is bactericidal, meaning it kills bacteria directly.

Mechanism Steps

1
Binding to penicillin-binding proteins: This medicine binds to specific penicillin-binding proteins located in the bacterial cell membrane.
2
Inhibition of cell wall synthesis: This binding blocks the transpeptidation reaction needed to cross-link peptidoglycan, weakening the cell wall.
3
Activation of autolysins: The weakened cell wall triggers bacterial enzymes called autolysins, which further degrade the cell wall.
4
Bacterial cell lysis: The bacterial cell can no longer withstand osmotic pressure and bursts, resulting in bacterial death.

💡 How to Take stancef o syrup

Strength: Cefixime 125mg per 5 mL oral syrup.

1Shake the bottle well before each use.
2Measure the dose using the provided measuring spoon or syringe.
3Take with or without food, but with food if it upsets your stomach.
4Swallow the syrup directly; do not mix with large amounts of liquid unless instructed.
5Complete the full course as prescribed, even if symptoms improve.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 200-400 mg per day, taken as a single daily dose or divided into two doses. For uncomplicated gonorrhea, a single 400 mg dose is recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function and may require dose adjustment. Dose must be individualized by a qualified clinician based on renal function.
Renal ImpairmentIn patients with creatinine clearance (CrCl) 20-60 mL/min, the dose should be reduced to 75% of the usual dose. In patients with CrCl <20 mL/min, the dose should be reduced to 50% of the usual dose. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
May take with or without food
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of stancef o syrup

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent or severe.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if it continues.
Stomach pain (Common (5-10%))
Take with food. If pain is severe or persistent, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or unusual.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, hives, swelling of face or throat, difficulty breathing, or dizziness.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop severe, persistent diarrhea, abdominal cramps, or fever.
Kidney problems (interstitial nephritis) (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Seek emergency care if you develop a painful rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Blood disorders such as thrombocytopenia, leukopenia, and eosinophilia
Elevated liver enzymes
Seizures (especially in patients with kidney impairment)
Hemolytic anemia
Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Carbamazepine Major
Probenecid Moderate
Furosemide Moderate
Aminoglycosides Moderate
Antacids Minor
Iron supplements Minor

🚨 Major Interactions

  • Warfarin
  • Carbamazepine
  • Probenecid

⚡ Moderate Interactions

  • Loop diuretics (e.g., furosemide)
  • Aminoglycosides

🍷 Alcohol Interaction

Alcohol may worsen stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporins or penicillins","Previous severe allergic reaction to beta-lactam antibiotics","History of Clostridioides difficile-associated diarrhea"]

⚠️ Warnings & Precautions

["Use with caution in patients with kidney impairment; dose adjustment may be needed.","May cause false-positive results in urine glucose tests.","Prolonged use may lead to bacterial or fungal superinfection.","Avoid in patients with a history of penicillin allergy due to cross-reactivity.","Do not use for viral infections."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but monitor the infant for diarrhea or thrush. Consult your doctor.

💊 Overdose Management

Overdose may cause nausea, vomiting, stomach pain, and diarrhea. In severe cases, seizures may occur. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases with renal failure. Contact a poison control center or emergency room immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early. Shake the bottle well before each use. Measure the dose with the provided spoon or syringe, not a household spoon. Inform your doctor if you have kidney problems, allergies, or are pregnant or breastfeeding. Avoid alcohol while taking this medicine. Do not share this medicine with others.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require dose adjustment. Monitor for signs of superinfection and renal impairment.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe in pregnancy but use only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help flush out bacteria.
🥗
Get plenty of rest to support your immune system.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Practice good hygiene to prevent reinfection.
🧘
Avoid close contact with others if you have a contagious infection.

🏋️ Exercise Considerations

If you feel dizzy or weak, avoid strenuous exercise. Light activity is fine if you feel up to it.

🥗 Diet Recommendations

Include probiotics like yogurt to prevent diarrhea.
Stay hydrated with water and clear fluids.
Avoid alcohol and caffeine which can worsen stomach upset.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness in some people. Avoid driving or operating heavy machinery if you experience these effects. Most people can continue their normal activities.

🛑 When to Stop This Medicine

Stop taking this medicine only after completing the full course prescribed by your doctor. Do not stop early even if you feel better, as this can lead to recurrence and resistance. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance and superinfections. It is not intended for prolonged use unless directed by a doctor. Regular monitoring of kidney and liver function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help prevent antibiotic-associated diarrhea.

Evidence: Well-established
Pain relievers

For symptom relief while the antibiotic takes effect.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Avoid vaccination during treatment and for a few days after.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Declare it at customs if required. Do not store in checked luggage where temperature may fluctuate.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 5-year-old child with recurrent ear infection
The child was prescribed this medicine for otitis media. The parents administered it with food twice daily. Within 3 days, the child's ear pain and fever subsided. The full 10-day course was completed to prevent recurrence.
💡 Lesson: Completing the full course and taking with food improves outcomes and reduces stomach upset.
👤 A 30-year-old woman with urinary tract infection
She was prescribed this medicine for a UTI. She took it as directed and noticed symptom relief within 2 days. She completed the 7-day course and her infection cleared.
💡 Lesson: Adherence to the prescribed duration is crucial to eradicate the infection completely.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-2 days, but complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.

Q: Is it safe for children?

A: It is commonly used in children, but the dose must be determined by a pediatrician based on weight and condition.

Q: What if I miss a dose?

A: Take it as soon as you remember. If it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for stancef o syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine is an antibiotic and only works against bacterial infections. It is not effective against viruses.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Cefixime 125mg/5mL oral suspension (various manufacturers)

Brand Alternatives

  • Taxim-O 125
  • Zifi 125
  • Cefolac 125
  • Omnicef 125

📊 Comparison with Similar Medicines

[{"medicine":"Cefixime","class":"Third-generation cephalosporin","route":"Oral","common_use":"Ear, throat, urinary tract infections"},{"medicine":"Cefpodoxime","class":"Third-generation cephalosporin","route":"Oral","common_use":"Respiratory, urinary tract infections"},{"medicine":"Amoxicillin-clavulanate","class":"Penicillin + beta-lactamase inhibitor","route":"Oral","common_use":"Sinusitis, otitis media, respiratory infections"}]

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