Flulen Injection (Flucloxacillin Sodium 1000mg): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe or persistent diarrhea, abdominal pain, or fever
- Yellowing of skin or eyes, dark urine, or right upper abdominal pain
- Unusual bleeding or bruising
- Decreased urine output or swelling in legs
- Seizures or confusion
- Severe injection site pain or redness
If experiencing severe symptoms, call emergency services immediately.
What is staflowin injection used for?
This medicine is a penicillinase-resistant penicillin antibiotic used to treat serious bacterial infections caused by susceptible Gram-positive bacteria, including skin, bone, and bloodstream infections. It is given by injection under medical supervision.
- Generic Name: Flucloxacillin Sodium (1000mg)
- Manufacturer: Converge Biotech
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 staflowin injection के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लुक्लोक्सासिलिन सोडियम का इंजेक्शन है, जिसका उपयोग गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह विशेष रूप से उन बैक्टीरिया के खिलाफ प्रभावी है जो पेनिसिलिन को नष्ट करने वाले एंजाइम बनाते हैं, जैसे स्टैफिलोकोकस ऑरियस। इसका उपयोग त्वचा और मांसपेशियों के संक्रमण, हड्डियों और जोड़ों के संक्रमण, निमोनिया, और रक्त संक्रमण के इलाज में किया जाता है। यह दवा केवल डॉक्टर की देखरेख में इंजेक्शन के रूप में दी जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, सूजन या लालिमा, मतली, उल्टी, दस्त और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी की प्रतिक्रिया, गंभीर दस्त, यकृत की समस्या, रक्त विकार और गुर्दे की समस्या शामिल हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। उपयोग से पहले अपने डॉक्टर को पेनिसिलिन या सेफलोस्पोरिन से एलर्जी, यकृत या गुर्दे की बीमारी के बारे में बताएं। एलर्जी के लक्षण जैसे चकत्ते, खुजली, सूजन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर को बताएं। गुर्दे की बीमारी में खुराक समायोजन की आवश्यकता हो सकती है।
💊 staflowin injection Uses & Benefits
[{"condition":"Skin and soft tissue infections","description":"Effective against cellulitis, abscesses, and wound infections caused by susceptible Gram-positive bacteria, especially Staphylococcus aureus.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"Used in osteomyelitis and septic arthritis caused by penicillinase-producing Staphylococcus aureus.","evidence":"Well-established"},{"condition":"Pneumonia","description":"Treats community-acquired and hospital-acquired pneumonia when caused by susceptible staphylococci.","evidence":"Well-established"},{"condition":"Endocarditis","description":"Used in the treatment of infective endocarditis caused by susceptible staphylococci, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Bacteremia","description":"Treats bloodstream infections caused by susceptible Gram-positive organisms.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prophylaxis in orthopedic surgery","description":"Sometimes used perioperatively to prevent surgical site infections in patients with penicillin allergy alternatives.","evidence":"Limited"}]
Primary treatment for: Bacterial infections caused by susceptible Gram-positive organisms
Also treats: Skin and soft tissue infections, Bone and joint infections, Pneumonia, Endocarditis, Bacteremia
📋 Drug Information
| Generic Name(s) | Flucloxacillin Sodium (1000mg) |
| Brand Name | staflowin injection |
| Manufacturer | Converge Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cell wall active agent- Penicillinase resistant Penicillin |
| Route of Administration | Parenteral (intramuscular or intravenous injection) |
| Storage | Store below 25°C, protected from light. Do not freeze. Reconstituted solutions should be used immediately or stored as per manufacturer's instructions. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Flucloxacillin sodium is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the transpeptidation reaction, preventing cross-linking of peptidoglycan chains, which is essential for cell wall integrity. The result is bacterial cell lysis and death, particularly in actively dividing bacteria. Flucloxacillin is resistant to hydrolysis by penicillinase enzymes produced by certain staphylococci, making it effective against penicillinase-producing Staphylococcus aureus.
Mechanism Steps
💡 How to Take staflowin injection
Strength: Injection: 1000 mg
Dosage Information
| Adult Dosage | The usual adult dose is 250 mg to 2 g every 4 to 6 hours by intramuscular or intravenous injection, depending on the severity and type of infection. For severe infections, higher doses may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function; dose adjustment may be necessary based on creatinine clearance. Use with caution and monitor renal function. |
| Renal Impairment | In patients with renal impairment, dose reduction or increased dosing interval may be required. For creatinine clearance less than 10 mL/min, the dose should be reduced. Consult a clinician for specific adjustments. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment, but use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Doses up to 12 g per day have been used in severe infections under close medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of staflowin injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Aminoglycosides | Moderate |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Aminoglycosides
🍷 Alcohol Interaction
Alcohol may increase the risk of liver toxicity and should be avoided during treatment with this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to penicillins or cephalosporins","History of severe allergic reaction to beta-lactam antibiotics","Previous flucloxacillin-associated jaundice or hepatic dysfunction"]
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment; dose adjustment may be required.","Use with caution in patients with hepatic impairment; monitor liver function.","Serious and occasionally fatal hypersensitivity reactions can occur.","Prolonged use may result in overgrowth of non-susceptible organisms.","Avoid in patients with a history of flucloxacillin-associated jaundice.","Not effective against MRSA or viral infections."]
🤱 Lactation Safety
Flucloxacillin is excreted in breast milk in low concentrations. It is generally considered safe during breastfeeding, but monitor the infant for diarrhea or thrush. Consult your doctor.
💊 Overdose Management
Overdose may cause gastrointestinal symptoms, electrolyte imbalance, and seizures. Treatment is symptomatic and supportive. Flucloxacillin is not significantly removed by hemodialysis. In case of overdose, seek immediate medical attention.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your healthcare provider for instructions. Do not attempt to self-administer.
Additional Safety Advice
This medicine must only be administered by a qualified healthcare professional. Before use, inform your doctor about any allergies, especially to penicillins or cephalosporins, and any history of liver or kidney disease. Do not self-administer. Report any signs of allergic reaction such as rash, itching, swelling, or difficulty breathing immediately. Use with caution in patients with renal impairment; dose adjustment may be necessary. Prolonged use may lead to fungal or bacterial superinfections. Ensure adequate hydration during treatment. Do not use if the solution is discolored or contains particles.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced renal function and may require dose adjustment. They are also at higher risk of liver toxicity and should be monitored closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. It is generally considered safe in pregnancy when clearly needed, but the benefits and risks should be weighed.
🏥 Post-Surgery Considerations
This medicine may be used to prevent or treat surgical site infections. Inform your surgeon if you are allergic to penicillin. It is usually administered in the hospital setting.
🦷 Dental Procedures
This medicine may be used for dental infections or prophylaxis in patients with certain heart conditions. Inform your dentist if you are allergic to penicillin.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during treatment, especially if you have a fever or are feeling weak. Light activity is fine, but listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you experience these effects. You may need to take time off work during treatment, especially if hospitalized.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping early may lead to recurrence of infection and antibiotic resistance. Your doctor will determine the appropriate duration based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to liver toxicity, blood disorders, and superinfections. Regular monitoring of liver and kidney function is recommended for prolonged therapy. When used appropriately for a defined duration, the risk of long-term effects is low.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For milder infections, oral antibiotics like flucloxacillin capsules may be used instead of injections.
Evidence: Well-establishedIf allergic to penicillin, alternative antibiotics like clindamycin or vancomycin may be considered.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your doctor about your vaccination status, especially for tetanus, as it may be relevant for wound infections.
📦 Storage Guide
✅ DO
Store below 25°C, protected from light
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Use reconstituted solution immediately
❌ DON'T
Do not store reconstituted solution for later use
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Since it is an injectable, it is usually administered by a healthcare professional. If you need to travel with it, ensure proper storage (below 25°C, protected from light) and carry a doctor's note explaining its medical necessity. Check customs regulations for injectable medications in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes to 1 hour after injection, but you may not feel better immediately. Improvement in symptoms usually occurs within 24-48 hours.
A: No, this medicine must be administered by a healthcare professional in a clinic or hospital setting.
A: Report any side effects to your doctor immediately. Mild side effects like nausea or injection site pain are common, but severe reactions require urgent medical attention.
🤔 Common Patient Concerns
🔄 Substitutes for staflowin injection
View AllAlternative brands with exact same active ingredient:
-
flulen injectionPollen Healthcure Pvt. Ltd. ₹749.00 60.1% COSTLIER
-
stafocid 1g injectionStrathspey Labs Pvt Ltd ₹749.06 60.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: This medicine is safe for everyone.
Fact: This medicine can cause serious allergic reactions and is not safe for individuals with penicillin allergy. - Myth: You can stop this medicine once you feel better.
Fact: You must complete the full course as prescribed by your doctor to prevent recurrence and resistance.
🔄 Alternative Options
Generic Alternatives
- Flucloxacillin sodium injection
Brand Alternatives
- Flulen injection