ciractam 1.5gm injection - Cefpirome (1000mg) + Sulbactam (500mg) medicine

ciractam 1.5gm injection

4.6 (14 reviews)
๐Ÿญ Converge Biotech ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is ciractam 1.5gm injection used for?

Ciraclam (Cefpirome + Sulbactam) is used to treat ANTI INFECTIVES. It contains Cefpirome (1000mg) + Sulbactam (500mg), which Cefpirome inhibits bacterial cell wall synthesis by binding to penicillin-bindin. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cefpirome + Sulbactam
  • Manufacturer: Converge Biotech
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š ciractam 1.5gm injection Uses & Benefits

Treatment of infections caused by susceptible organisms: respiratory tract infections, urinary tract infections, skin and soft tissue infections, septicemia, intra-abdominal infections.

Off-label uses: Bone and joint infections, Febrile neutropenia

๐Ÿ“‹ Drug Information

Generic Name(s)Cefpirome + Sulbactam
Brand NameCiraclam
ManufacturerConverge Biotech
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporin + Beta-lactamase inhibitor
Route of AdministrationIntramuscular or intravenous
StorageStore at 20-25ยฐC; protect from light. Reconstituted solution stable for 24 hours at room temperature.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular or intravenous administration results in complete bioavailability.
DistributionWidely distributed in body tissues and fluids, including cerebrospinal fluid.
Protein BindingCefpirome: ~10%; Sulbactam: ~38%
MetabolismCefpirome: minimally metabolized; Sulbactam: metabolized to a minor extent.
Half-LifeCefpirome: ~2 hours; Sulbactam: ~1 hour
ExcretionPrimarily renal excretion (unchanged drug).
Bioavailability100% (IV/IM)
Onset of ActionRapid (within minutes after IV administration)
Peak Plasma TimeEnd of IV infusion or 30-60 min after IM injection
Duration of ActionApproximately 8-12 hours

How It Works

Cefpirome inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Sulbactam irreversibly inhibits beta-lactamases, preventing degradation of cefpirome.

Mechanism Steps

1Cefpirome binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
2Inhibition of transpeptidase enzymes prevents cross-linking of peptidoglycan chains.
3Autolytic enzymes are activated, leading to cell lysis and death.

๐Ÿ’ก How to Take ciractam 1.5gm injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of ciractam 1.5gm injection

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Injection site reactions

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Clostridioides difficile colitis
  • Seizures
  • Acute renal failure

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Probenecid Major Decreased renal excretion of cefpirome, increased plasma levels and toxicity risk.
Aminoglycosides Major Increased risk of nephrotoxicity.
Loop diuretics Major Increased risk of nephrotoxicity.
Oral anticoagulants Moderate Potentiation of anticoagulant effect.
Live typhoid vaccine Moderate Reduced immunological response to vaccine.
BCG vaccine Minor Reduced vaccine efficacy.
Cholera vaccine Minor Reduced vaccine efficacy.

๐Ÿšจ Major Interactions

  • Probenecid
  • Aminoglycosides
  • Loop diuretics

โšก Moderate Interactions

  • Oral anticoagulants
  • Live typhoid vaccine

โ„น๏ธ Minor Interactions

  • BCG vaccine
  • Cholera vaccine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No disulfiram-like reaction reported.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cephalosporins, penicillins, or beta-lactamase inhibitors.

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, CBC, signs of hypersensitivity, superinfection.

๐Ÿคฑ Lactation Safety

Caution; excreted in breast milk in low concentrations.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Administer as soon as remembered; if near next dose, skip missed dose and resume regular schedule.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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