Dexbro Syrup: Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of face, lips, or throat
- Severe dizziness or fainting
- Hallucinations or confusion
- Chest pain or rapid heartbeat
- Cough with blood or rust-colored sputum
- Fever lasting more than 3 days
If experiencing severe symptoms, call emergency services immediately.
What is siokof p syrup used for?
This medicine is a combination cough syrup containing bromhexine (mucolytic) and dextromethorphan (cough suppressant). It is used for temporary relief of dry, irritating cough. It should not be used for more than 7 days without medical advice.
- Generic Name: Bromhexine (NA) + Dextromethorphan Hydrobromide (NA)
- Manufacturer: Albert David Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 siokof p syrup के बारे में (Hindi Summary)
उपयोग: यह दवा ब्रोंकाइटिस और डेक्सट्रोमेथोर्फन का संयोजन है, जिसका उपयोग सूखी, चिड़चिड़ी खांसी के अस्थायी राहत के लिए किया जाता है। यह बलगम को पतला करती है और खांसी की प्रतिक्रिया को कम करती है। यह आम सर्दी या हल्के श्वसन संक्रमण से जुड़ी खांसी में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मतली, उल्टी, पेट में परेशानी और सिरदर्द शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई, या मतिभ्रम हो सकते हैं। यदि ऐसा हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा की अनुशंसित खुराक से अधिक न लें। गाड़ी चलाने या मशीनरी चलाने से बचें जब तक आप जान न लें कि यह दवा आपको कैसे प्रभावित करती है। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। 7 दिनों से अधिक इस दवा का उपयोग न करें।
💊 siokof p syrup Uses & Benefits
[{"condition":"Dry, irritating cough","description":"Helps suppress the cough reflex and reduce throat irritation associated with dry cough.","evidence":"Well-established"},{"condition":"Productive cough with thick mucus","description":"Bromhexine thins mucus, making it easier to expel, while dextromethorphan reduces excessive coughing.","evidence":"Moderate"},{"condition":"Cough due to common cold","description":"Provides symptomatic relief of cough associated with upper respiratory tract infections.","evidence":"Moderate"}]
Off-label uses: []
Primary treatment for: Cough
Also treats: Common cold, Upper respiratory tract infection, Bronchitis
📋 Drug Information
| Generic Name(s) | Bromhexine (NA) + Dextromethorphan Hydrobromide (NA) |
| Brand Name | siokof p syrup |
| Manufacturer | Albert David Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a mucolytic and a centrally acting cough suppressant. Bromhexine works by breaking down the structure of acidic mucopolysaccharide fibers in mucus, reducing its viscosity and making it easier to clear from the airways. Dextromethorphan hydrobromide acts on the cough center in the medulla oblongata in the brain, raising the threshold for coughing and thereby reducing the frequency and intensity of the cough reflex. It does not have analgesic or respiratory depressant effects at usual doses.
Mechanism Steps
💡 How to Take siokof p syrup
Strength: Each 5 ml of syrup contains bromhexine hydrochloride 4 mg and dextromethorphan hydrobromide 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 ml (two teaspoons) three times a day, or as directed by a physician. The dose may vary based on the severity of cough and individual response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult a doctor. |
| Hepatic Impairment | Dose adjustment may be required in patients with hepatic impairment. Consult a doctor. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 30 ml (6 teaspoons) in divided doses. Do not exceed this without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of siokof p syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| SSRIs | Major | |
| CYP2D6 inhibitors | Major | |
| Alcohol | Moderate | |
| Benzodiazepines | Moderate | |
| Opioids | Moderate | |
| Antihistamines | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- SSRIs (e.g., fluoxetine, paroxetine)
- CYP2D6 inhibitors (e.g., quinidine, terbinafine)
⚡ Moderate Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Antihistamines (e.g., diphenhydramine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of respiratory depression. It may also worsen stomach irritation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to bromhexine or dextromethorphan","Concurrent use with MAO inhibitors","Children under 12 years (unless prescribed)","Chronic cough with excessive mucus","Severe liver or kidney impairment"]
⚠️ Warnings & Precautions
["Do not exceed recommended dose","Avoid driving or operating machinery until you know how it affects you","Avoid alcohol","Consult doctor if cough persists more than 7 days","Use with caution in patients with asthma or COPD","Not for use in children under 12 without medical advice"]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before use.
💊 Overdose Management
Overdose may cause severe drowsiness, dizziness, nausea, vomiting, hallucinations, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote for dextromethorphan; naloxone may be used in severe respiratory depression. Bromhexine overdose may cause gastrointestinal upset. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Do not exceed the recommended dose of this medicine. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness. Do not consume alcohol while taking this medicine, as it can increase drowsiness and impair judgment. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. If you have a history of liver disease, kidney disease, or chronic respiratory conditions like asthma, use only under medical supervision. Do not take this medicine if you are currently taking a monoamine oxidase inhibitor (MAOI) or have taken one in the last 14 days.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and confusion. Use with caution and consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medicine during pregnancy is not established.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may cause dry mouth or interact with anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine, especially if you experience drowsiness or dizziness. Light activity is fine if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take it when you can rest.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if your cough persists for more than 7 days, worsens, or is accompanied by fever, rash, or difficulty breathing. Do not stop abruptly if you have been taking it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use may lead to rebound cough, increased mucus production, or masking of underlying conditions. It should only be used for short-term symptomatic relief. If cough persists beyond 7 days, consult a doctor for evaluation.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and soothe airways.
Evidence: Well-establishedSoothes throat and reduces cough.
Evidence: ModerateHelps clear nasal congestion.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccination timing if you are due for any vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying medicines. Keep it in carry-on luggage if possible.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to an hour after taking it. The cough suppressant effect lasts for about 4-6 hours.
A: You should consult a doctor before combining with other cold medicines, as they may contain overlapping ingredients or interact.
A: This medicine is not recommended for children under 12 years without medical advice. Consult a pediatrician for appropriate dosing.
🤔 Common Patient Concerns
🔄 Substitutes for siokof p syrup
View AllAlternative brands with exact same active ingredient:
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cofout tabletMDC Pharmaceuticals Pvt Ltd ₹3.52 84% CHEAPER
-
Swicof SyrupInd Swift Laboratories Ltd ₹16.24 26.1% CHEAPER
-
Rantussin D SyrupSun Pharmaceutical Industries Ltd ₹16.41 25.4% CHEAPER
-
aa ha tabletLeo Pharmaceuticals ₹22.86 4% COSTLIER
-
cadex syrupZydus Healthcare Limited ₹30.00 36.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for dry, irritating cough. It is not effective for cough with excessive phlegm or chronic cough. - Myth: It is safe to take this medicine for weeks.
Fact: This medicine should not be used for more than 7 days without consulting a doctor. - Myth: It is safe for children.
Fact: This medicine is not recommended for children under 12 years without medical advice.
🔄 Alternative Options
Generic Alternatives
- Bromhexine + Dextromethorphan syrup (generic)
Brand Alternatives
- Dexbro Syrup