Secold Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe headache with blurred vision or confusion
- Chest pain, palpitations, or irregular heartbeat
- Difficulty breathing or swelling of face, lips, or throat
- Yellowing of skin or eyes, dark urine, or severe abdominal pain
- Unusual bleeding or bruising
- Seizures or hallucinations
If experiencing severe symptoms, call emergency services immediately.
What is secold syrup used for?
This medicine is a combination syrup containing Paracetamol and Phenylpropanolamine, used for temporary relief of cold symptoms like nasal congestion, headache, and fever. It works by reducing pain and fever and shrinking nasal blood vessels.
- Generic Name: Paracetamol (125mg) + Phenylpropanolamine (10mg)
- Manufacturer: Anrose Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 secold syrup के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और फेनिलप्रोपेनॉलामाइन का संयोजन है, जिसका उपयोग सर्दी-जुकाम के लक्षणों जैसे नाक बंद होना, सिरदर्द, बदन दर्द और बुखार से राहत के लिए किया जाता है। यह दवा दर्द और बुखार को कम करने और नाक की भीड़ को कम करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, जी मिचलाना और सिरदर्द शामिल हो सकते हैं। कभी-कभी रक्तचाप बढ़ सकता है या दिल की धड़कन तेज हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको गंभीर सिरदर्द, धुंधली दृष्टि, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के निर्देशानुसार ही करें। अनुशंसित खुराक से अधिक न लें। यदि आपको नींद या चक्कर आते हैं तो वाहन चलाने या मशीनरी चलाने से बचें। उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड या ग्लूकोमा होने पर डॉक्टर को सूचित करें। शराब का सेवन न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें।
💊 secold syrup Uses & Benefits
[{"condition":"Common cold","description":"Provides symptomatic relief of nasal congestion, headache, body ache, and fever associated with the common cold.","evidence":"Well-established for short-term symptomatic relief"},{"condition":"Allergic rhinitis","description":"Helps reduce nasal stuffiness and associated discomfort in allergic rhinitis.","evidence":"Limited evidence; used for symptomatic relief"},{"condition":"Sinusitis","description":"May alleviate nasal congestion and pain in acute sinusitis as an adjunct to other treatments.","evidence":"Limited evidence; used for symptomatic relief"}]
Off-label uses: []
Primary treatment for: Common cold
Also treats: Allergic rhinitis, Sinusitis
📋 Drug Information
| Generic Name(s) | Paracetamol (125mg) + Phenylpropanolamine (10mg) |
| Brand Name | secold syrup |
| Manufacturer | Anrose Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Paracetamol acts primarily in the central nervous system to reduce fever and pain by inhibiting prostaglandin synthesis. Phenylpropanolamine is a sympathomimetic amine that stimulates alpha-adrenergic receptors, causing vasoconstriction in the nasal mucosa, which reduces swelling and congestion. The combination provides both analgesic-antipyretic and decongestant effects.
Mechanism Steps
💡 How to Take secold syrup
Strength: Each 5 mL of syrup contains Paracetamol 125 mg and Phenylpropanolamine 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10-15 mL (2-3 teaspoons) every 4-6 hours as needed for symptoms, not to exceed 60 mL in 24 hours. However, dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for more than 5 days without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on the child's age and weight. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of phenylpropanolamine, especially on blood pressure and heart rate. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | For adults, the maximum daily dose is 60 mL of syrup (providing 1500 mg paracetamol and 120 mg phenylpropanolamine). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of secold syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Warfarin | Major | |
| Beta-blockers | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Alcohol | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other sympathomimetic amines
- Warfarin
⚡ Moderate Interactions
- Beta-blockers
- Tricyclic antidepressants
- Alcohol
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage from paracetamol and may worsen drowsiness or dizziness caused by the combination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to paracetamol, phenylpropanolamine, or any component of the formulation","Severe hypertension or coronary artery disease","Use within 14 days of monoamine oxidase inhibitors","Severe liver disease","Children under 2 years of age (unless directed by a doctor)"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose; high doses of paracetamol can cause liver damage.","Avoid use in patients with high blood pressure, heart disease, diabetes, thyroid disorders, or glaucoma unless directed by a doctor.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use with other products containing paracetamol or phenylpropanolamine.","Consult a doctor if symptoms persist beyond 5 days or are accompanied by high fever.","Keep out of reach of children."]
🤱 Lactation Safety
Paracetamol is considered safe during breastfeeding in usual doses. Phenylpropanolamine may pass into breast milk and could affect the infant. Consult a doctor before use.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and hypertensive crisis due to phenylpropanolamine. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care for hypertension.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Use this medicine only as directed by your doctor. Do not exceed the recommended dose or duration of use. Avoid driving or operating heavy machinery if you feel drowsy or dizzy. Do not take this medicine with other products containing paracetamol or phenylpropanolamine to prevent overdose. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, or glaucoma. Avoid alcohol while taking this medicine as it may increase drowsiness and liver risk. Pregnant or breastfeeding women should consult a doctor before use. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the cardiovascular effects of phenylpropanolamine, such as increased blood pressure and heart rate. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of phenylpropanolamine during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect blood pressure and healing.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with anesthetics or other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. If you feel dizzy, lie down and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to rest and take time off work if symptoms are severe.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if your symptoms do not improve within 5 days, if they worsen, or if you experience any serious side effects such as severe headache, chest pain, or allergic reactions.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol can increase the risk of liver damage, especially with high doses or alcohol consumption. Phenylpropanolamine can cause persistent elevation in blood pressure and cardiac effects. Regular monitoring of liver and kidney function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps moisturize and clear nasal passages without medication.
Evidence: Well-established for mild congestion.Can temporarily relieve nasal congestion.
Evidence: Limited evidence but commonly used.Supports the body's natural recovery from colds.
Evidence: Well-established.💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription to avoid customs issues. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue your regular dosing schedule as prescribed. Do not leave it in a hot car or checked luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to relieve symptoms within 30-60 minutes after taking a dose.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the recommended dose can lead to serious side effects, including liver damage and high blood pressure.