scool 25 tablet - Quetiapine (25mg) medicine

Quetiapine 25mg Tablet: Complete Information

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🏭 Shatayushi Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • High fever with muscle rigidity and confusion
  • Involuntary movements of tongue, face, or limbs
  • Severe dizziness or fainting
  • Palpitations or irregular heartbeat
  • Rash, swelling of face or throat, difficulty breathing
  • Yellowing of eyes or skin
  • Suicidal thoughts or worsening depression
  • Severe abdominal pain with nausea and vomiting

If experiencing severe symptoms, call emergency services immediately.

What is scool 25 tablet used for?

This medicine is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, and as an add-on for major depressive disorder. It works by balancing dopamine and serotonin in the brain. It is available as a 25 mg immediate-release tablet and must be taken under medical supervision.

  • Generic Name: Quetiapine (25mg)
  • Manufacturer: Shatayushi Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 scool 25 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा क्वेटियापिन 25 मिलीग्राम की गोली है, जिसका उपयोग सिज़ोफ्रेनिया, बाइपोलर डिसऑर्डर और अवसाद के इलाज में किया जाता है। यह मस्तिष्क में डोपामाइन और सेरोटोनिन को संतुलित करके काम करती है। यह मतिभ्रम, भ्रम, मूड स्विंग्स और चिंता को कम करने में मदद करती है। इसका सेवन डॉक्टर की सलाह के अनुसार ही करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, वजन बढ़ना और कब्ज शामिल हैं। गंभीर दुष्प्रभावों में न्यूरोलेप्टिक मैलिग्नेंट सिंड्रोम, टार्डिव डिस्किनेसिया और हृदय की धड़कन में बदलाव हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को चबाएं नहीं, पूरा निगल लें। शराब और अन्य नींद लाने वाली दवाओं से बचें। जब तक पता न चले कि यह दवा आप पर कैसा असर करती है, वाहन न चलाएं। अचानक दवा बंद न करें। नियमित जांच कराते रहें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 scool 25 tablet Uses & Benefits

[{"condition":"Schizophrenia","description":"Reduces positive symptoms like hallucinations and delusions, and improves negative symptoms and cognitive function.","evidence":"Well-established"},{"condition":"Bipolar mania","description":"Helps control acute manic episodes and prevents relapse.","evidence":"Well-established"},{"condition":"Bipolar depression","description":"Effective in treating depressive episodes associated with bipolar disorder.","evidence":"Well-established"},{"condition":"Major depressive disorder (adjunct)","description":"Used as an add-on to antidepressants for treatment-resistant depression.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Insomnia","description":"Low doses are sometimes prescribed off-label for sleep difficulties, especially in psychiatric patients.","evidence":"Limited"},{"condition":"Anxiety disorders","description":"May be used off-label for generalized anxiety disorder or panic disorder when other treatments fail.","evidence":"Limited"},{"condition":"Post-traumatic stress disorder (PTSD)","description":"Sometimes used off-label to reduce nightmares and hyperarousal.","evidence":"Limited"}]

Primary treatment for: Schizophrenia

Also treats: Bipolar disorder, Major depressive disorder

📋 Drug Information

Generic Name(s)Quetiapine (25mg)
Brand Namescool 25 tablet
ManufacturerShatayushi Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAtypical Antipsychotics
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place. Keep away from direct sunlight and moisture.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain steady levels.
2
Avoid driving or operating machinery until you know how this medicine affects you.
3
Rise slowly from sitting or lying positions to prevent dizziness.
4
Monitor your weight and waist circumference regularly; report rapid weight gain to your doctor.
5
Do not stop this medicine abruptly; always taper under medical supervision.
6
Report any involuntary movements, fever, or muscle rigidity immediately.
7
Limit alcohol and caffeine intake while on this medicine.
8
Keep all follow-up appointments for blood tests and eye exams.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Hallucinations
This medicine is commonly prescribed for this.
Likely Use
✅
Mood swings
This medicine helps stabilize mood.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration. Food does not significantly affect the extent of absorption but may slightly delay the time to peak concentration.
DistributionWidely distributed throughout the body. It crosses the blood-brain barrier and placenta. It is also excreted in breast milk.
Protein BindingApproximately 83% bound to plasma proteins.
MetabolismExtensively metabolized in the liver, primarily by CYP3A4. The major metabolite, norquetiapine, has some pharmacological activity.
Half-LifeAbout 6 to 7 hours for quetiapine; norquetiapine has a half-life of about 12 hours.
ExcretionPrimarily excreted in urine (73%) and feces (20%) as metabolites. Less than 1% is excreted unchanged.
BioavailabilityApproximately 9% due to extensive first-pass metabolism.
Onset of ActionSedation may occur within 30 to 60 minutes. Antipsychotic effects may take several days to weeks.
Peak Plasma TimeAbout 1.5 hours after oral administration.
Duration of ActionSedative effects last about 6 to 8 hours. Antipsychotic effects require continuous dosing.

How It Works

This medicine works by blocking dopamine type 2 (D2) and serotonin type 2A (5-HT2A) receptors in the brain. It also interacts with histamine H1 and adrenergic alpha-1 receptors, which contributes to sedation and orthostatic hypotension. The exact mechanism for its mood-stabilizing effects is not fully understood but likely involves a balance of dopamine and serotonin modulation.

Mechanism Steps

1
D2 receptor antagonism: Blocks dopamine D2 receptors in mesolimbic pathway, reducing positive symptoms of schizophrenia.
2
5-HT2A receptor antagonism: Blocks serotonin 5-HT2A receptors, which helps reduce negative symptoms and improves mood.
3
H1 receptor blockade: Causes sedation and weight gain due to histamine H1 blockade.
4
Alpha-1 receptor blockade: Leads to orthostatic hypotension and dizziness.

💡 How to Take scool 25 tablet

Strength: 25 mg immediate-release tablet

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Do not crush, chew, or break the tablet.
4Take at the same time each day.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe dose is individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. For schizophrenia, the usual starting dose is 25 mg twice daily, titrated up to 300-400 mg daily in divided doses. For bipolar mania, similar titration. For bipolar depression, 300 mg once daily at bedtime. For adjunctive major depressive disorder, 50-300 mg once daily at bedtime. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageStart at a lower dose (e.g., 25 mg once daily) and titrate slowly. Elderly patients are more sensitive to side effects like drowsiness, dizziness, and orthostatic hypotension. Monitor closely.
Renal ImpairmentNo dose adjustment needed for renal impairment. However, use with caution and monitor.
Hepatic ImpairmentStart at 25 mg once daily and titrate slowly. Use with caution in hepatic impairment.
Maximum Daily Dose800 mg per day in divided doses, but doses above 400 mg are rarely used. Individualized by clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with or without food
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of scool 25 tablet

✅ Common Side Effects

Drowsiness (Very common (>10%))
Avoid driving. Usually improves with time. If persistent, consult doctor.
Dizziness (Common (5-10%))
Stand up slowly. If severe, contact doctor.
Dry mouth (Common (5-10%))
Sip water, chew sugar-free gum. If severe, consult doctor.
Weight gain (Common (5-10%))
Monitor weight and diet. Consult doctor if rapid gain.
Constipation (Common (5-10%))
Increase fiber and fluids. If persistent, consult doctor.

🚨 Serious Side Effects

Neuroleptic malignant syndrome (Rare (<0.1%))
Seek immediate medical attention if high fever, muscle rigidity, confusion, or irregular pulse occurs.
Tardive dyskinesia (Rare (<0.1%))
Report any involuntary movements to doctor immediately.
QT prolongation (Uncommon (0.1-1%))
Inform doctor if palpitations or fainting occurs. Regular ECG monitoring may be needed.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if rash, swelling, or difficulty breathing occurs.

⚠️ Rare Side Effects

Cataracts
Regular eye exams recommended.
Seizures
Seek immediate medical attention.
Low white blood cell count
Report fever, sore throat, or infections.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Rifampin Major
Amiodarone Major
Alcohol Moderate
Lisinopril Moderate
Levodopa Moderate
Antacids Minor
Caffeine Minor
Warfarin Moderate
Fluoxetine Moderate

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)
  • QT-prolonging drugs (e.g., amiodarone, sotalol)

⚡ Moderate Interactions

  • Alcohol
  • Antihypertensives
  • Levodopa

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and difficulty concentrating, and may worsen mental health symptoms.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to quetiapine","Concomitant use with strong CYP3A4 inhibitors","Severe liver impairment","History of QT prolongation","Uncontrolled seizures"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving.","May cause orthostatic hypotension; rise slowly.","May increase risk of falls in elderly.","May cause metabolic changes; monitor weight and glucose.","May cause tardive dyskinesia; report involuntary movements.","May cause neuroleptic malignant syndrome; seek emergency care.","Do not stop abruptly; taper under medical supervision.","May increase risk of suicidal thoughts in young adults."]

🤱 Lactation Safety

Quetiapine is excreted in breast milk. Limited data. Consult doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, rapid heart rate, low blood pressure, and QT prolongation. Seek emergency medical attention immediately. Treatment is supportive and symptomatic. Contact poison control.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed. Do not crush, chew, or break the tablet; swallow it whole with water. Avoid alcohol and other central nervous system depressants because they can increase drowsiness and dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. Stand up slowly to avoid dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not stop this medicine abruptly without medical advice. Keep all appointments for blood tests, weight checks, and eye exams. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to side effects like drowsiness, dizziness, and orthostatic hypotension. Start at a lower dose and titrate slowly. Increased risk of falls and fractures. Monitor renal and hepatic function.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. This medicine may affect the fetus. Use effective contraception while taking this medicine. If you become pregnant, inform your doctor immediately.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and increase risk of hypotension. Do not stop without medical advice.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth, increasing risk of dental problems. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight through diet and exercise.
🥗
Engage in regular physical activity like walking or swimming.
😴
Practice good sleep hygiene.
💧
Avoid alcohol and recreational drugs.
🧘
Manage stress with relaxation techniques.
🌞
Stay socially connected and seek support.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise until you know how it affects you. Stay hydrated and rise slowly after exercise.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit sugary and high-fat foods to manage weight.
Stay well hydrated.
Include fiber to prevent constipation.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, affecting your ability to drive or operate machinery. It may also affect concentration. Discuss with your doctor before resuming work activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like neuroleptic malignant syndrome or tardive dyskinesia, seek immediate medical attention. Your doctor will decide if and when to stop.

📅 Long-Term Use Effects

Long-term use may increase risk of metabolic syndrome, weight gain, diabetes, and cardiovascular issues. Regular monitoring of weight, blood glucose, lipids, and blood pressure is essential. Tardive dyskinesia may occur with prolonged use. Eye exams for cataracts are recommended. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cognitive behavioral therapy

Can complement medicine for schizophrenia and bipolar disorder.

Evidence: Well-established
Lifestyle changes

Regular exercise, healthy diet, and sleep hygiene can improve symptoms.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions known. Consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage. Store at room temperature and avoid extreme heat. If crossing time zones, adjust dosing schedule gradually under medical advice. Check customs regulations for controlled substances.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old man with schizophrenia
He started this medicine at 25 mg twice daily and gradually increased to 200 mg twice daily. After 4 weeks, his hallucinations reduced significantly. He experienced drowsiness initially but it improved. He emphasizes taking it regularly and not skipping doses.
💡 Lesson: Consistent dosing and gradual titration are key to effectiveness and tolerability.
👤 A 45-year-old woman with bipolar depression
She was prescribed this medicine 25 mg at bedtime, increased to 300 mg. Her mood improved over 6 weeks. She monitored her weight and diet to manage weight gain. She advises others to be patient and communicate with their doctor about side effects.
💡 Lesson: Regular follow-up and lifestyle adjustments help manage side effects and improve outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Sedation may occur within 30-60 minutes. Antipsychotic effects may take several days to weeks. Full benefits may take 4-6 weeks.

Q: Can I stop this medicine suddenly?

A: No, stopping suddenly can cause withdrawal symptoms or relapse. Always consult your doctor for a gradual taper.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Will I gain weight?
  • Is it safe during pregnancy?

🔄 Substitutes for scool 25 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is addictive.
    Fact: This medicine is not addictive in the traditional sense, but it can cause dependence and withdrawal symptoms if stopped abruptly.
  • Myth: This medicine will cure my mental illness.
    Fact: This medicine manages symptoms but does not cure the underlying condition. It must be taken regularly.
  • Myth: I can stop this medicine once I feel better.
    Fact: Stopping suddenly can cause relapse or withdrawal. Always consult your doctor before stopping.

🔄 Alternative Options

Generic Alternatives

  • Quetiapine

Brand Alternatives

  • Qutipin 25 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Quetiapine","class":"Atypical antipsychotic","sedation":"High","weight_gain":"Moderate","eps_risk":"Low","qt_risk":"Moderate"},{"medicine":"Olanzapine","class":"Atypical antipsychotic","sedation":"High","weight_gain":"High","eps_risk":"Low","qt_risk":"Low"},{"medicine":"Risperidone","class":"Atypical antipsychotic","sedation":"Moderate","weight_gain":"Moderate","eps_risk":"Moderate","qt_risk":"Low"}]

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