scabine lotion - Lindane (2% w/w) + Cetrimide (0.5% w/w) medicine

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🏭 Stadmed Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Lindane is not recommended for use during pregnancy unless the potential benefit justifies the potential risk to the fetus. It can cross the placenta and may cause fetal harm. Cetrimide is generally considered safe for topical use. Pregnant women should consult their doctor before using this medicine. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for scabies; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Seizures or convulsions
  • Severe dizziness or confusion
  • Difficulty breathing or swelling of face, lips, or throat
  • Extensive rash or blistering
  • Signs of systemic toxicity such as nausea, vomiting, or tremors
  • No improvement in symptoms after 2 weeks of treatment

If experiencing severe symptoms, call emergency services immediately.

What is scabine lotion used for?

This medicine is a medicated soap containing lindane and cetrimide, used to treat scabies and lice infestations. It works by killing the parasites and preventing bacterial infection. It should be used exactly as prescribed by a doctor.

  • Generic Name: Lindane (2% w/w) + Cetrimide (0.5% w/w)
  • Manufacturer: Stadmed Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 scabine lotion के बारे में (Hindi Summary)

उपयोग: यह दवा एक औषधीय साबुन है जिसमें लिंडेन (2% w/w) और सिट्रीमाइड (0.5% w/w) होते हैं। इसका उपयोग खुजली (स्केबीज) और जूँ के इलाज के लिए किया जाता है। यह त्वचा पर लगाने से परजीवियों को मारता है और संक्रमण को रोकता है। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में त्वचा में जलन, लालिमा, खुजली या हल्की जलन शामिल हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें चक्कर आना, दौरे पड़ना, या एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग केवल बाहरी त्वचा पर करें। इसे आंखों, मुंह, या घाव वाली त्वचा पर न लगाएं। बच्चों और गर्भवती महिलाओं में इसका उपयोग डॉक्टर की सलाह के बिना न करें। उपयोग के बाद हाथ धो लें। इसे बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 scabine lotion Uses & Benefits

  • [{"condition":"Scabies","description":"This medicine is used to treat scabies, a skin infestation caused by the Sarcoptes scabiei mite.
  • It helps to kill the mites and their eggs, relieving itching and preventing spread.","evidence":"Well-established"},{"condition":"Pediculosis (lice infestation)","description":"It may be used to treat lice infestations on the skin and hair, although other treatments are often preferred due to safety concerns with lindane.","evidence":"Established for certain cases"},{"condition":"Antiseptic skin cleansing","description":"Cetrimide provides antiseptic action, helping to cleanse the skin and reduce bacterial contamination in minor skin infections or before procedures.","evidence":"Supportive care"}]

Off-label uses: [{"condition":"Seborrheic dermatitis","description":"Occasionally used off-label for its antiseptic and anti-parasitic properties, but not a standard treatment.","evidence":"Limited"}]

Primary treatment for: Scabies

Also treats: Pediculosis, Secondary bacterial skin infections

📋 Drug Information

Generic Name(s)Lindane (2% w/w) + Cetrimide (0.5% w/w)
Brand Namescabine lotion
ManufacturerStadmed Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and heat. Keep the container tightly closed. Do not refrigerate unless specified. Keep out of reach of children and pets.
Shelf Life24 months from the date of manufacture, unless otherwise stated on the packaging.
WHO GuidelineNot established from the available information. WHO guidelines for scabies treatment often recommend permethrin or ivermectin as first-line, with lindane as an alternative in some settings.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine exactly as prescribed, usually to the entire body from the neck down for scabies.
2
Leave the soap on for the recommended time (often 8-12 hours) before washing off thoroughly.
3
Treat all household members and close contacts simultaneously to prevent reinfestation.
4
Wash all clothing, bedding, and towels in hot water and dry on high heat to kill mites.
5
Avoid using this medicine on broken skin or in the eyes, mouth, or genital area.
6
Do not use this medicine for more than the recommended duration without medical advice.
7
If you experience dizziness, seizures, or unusual skin reactions, stop use and seek medical help immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Intense itching, especially at night
This medicine is commonly prescribed for scabies, which causes nocturnal itching.
Likely Use
✅
Rash with small bumps or burrows
Typical of scabies infestation.
Likely Use
✅
Lice on scalp or body
This medicine can treat lice, though other treatments may be preferred.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Fungal infection
This medicine is not effective against fungi.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLindane can be absorbed through the skin, especially if the skin is damaged, inflamed, or if the product is used over a large area or for prolonged periods. Systemic absorption may lead to neurotoxic effects. Cetrimide is poorly absorbed through intact skin.
DistributionAbsorbed lindane is distributed to various tissues, including fat, liver, kidney, and brain. It can cross the blood-brain barrier and placenta. Cetrimide remains largely on the skin surface.
Protein BindingNot established from the available information.
MetabolismLindane is metabolized in the liver, primarily by cytochrome P450 enzymes, to various metabolites including chlorophenols and chlorobenzenes. Cetrimide is not significantly metabolized.
Half-LifeThe elimination half-life of lindane is reported to be approximately 17-22 hours, but this may vary. Cetrimide's half-life is not applicable due to minimal systemic absorption.
ExcretionLindane and its metabolites are excreted mainly in the urine and feces. Cetrimide is excreted unchanged in the feces if ingested, but topically it is washed off.
BioavailabilitySystemic bioavailability after topical application is variable and depends on the extent of application, skin condition, and duration. It is generally low but can be significant with damaged skin.
Onset of ActionThe antiparasitic effect on mites and lice begins within hours of application, but relief from itching may take several days as it is often due to an allergic reaction to the mites.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect lasts until the parasites are eradicated, typically after a single application, but a second application may be needed after 7 days to kill newly hatched mites.

How It Works

Lindane works by interfering with the function of gamma-aminobutyric acid (GABA) receptors in the nervous system of parasites. It binds to the GABA-gated chloride channels, preventing the influx of chloride ions, which leads to hyperexcitation and eventual death of the mites or lice. Cetrimide is a quaternary ammonium compound that acts as a surfactant and antiseptic. It disrupts the lipid membranes of bacteria and other microorganisms, leading to cell leakage and death. Together, they provide both antiparasitic and antiseptic effects.

Mechanism Steps

1
Lindane binding to GABA receptors: Lindane binds to GABA-gated chloride channels in the parasite's nervous system, blocking chloride ion flow.
2
Parasite hyperexcitation: The blockade leads to uncontrolled nerve firing, causing paralysis and death of the mite or louse.
3
Cetrimide membrane disruption: Cetrimide disrupts bacterial cell membranes, causing leakage of cellular contents and bacterial death.
4
Skin cleansing and antiseptic effect: The soap base helps remove debris and oils, while cetrimide reduces microbial load on the skin.

💡 How to Take scabine lotion

Strength: Medicated soap containing Lindane 2% w/w and Cetrimide 0.5% w/w.

1Read the label and follow your doctor's instructions carefully.
2Wet the skin with water.
3Apply the soap to the affected areas or as directed, avoiding eyes, mouth, and mucous membranes.
4Lather gently and leave on for the specified time (e.g., 8-12 hours for scabies).
5Rinse thoroughly with water.
6Wash your hands after application.
7Do not cover the area with tight bandages unless instructed.
8Clean clothing, bedding, and towels in hot water to prevent reinfestation.

Dosage Information

Adult DosageThe dosage of this medicine is individualized by a qualified clinician based on the condition being treated, the severity of the infestation, and the patient's age, weight, and overall health. Typically, for scabies, the soap is applied to the entire body from the neck down, left on for a specified time (usually 8-12 hours), and then washed off thoroughly. A second application may be recommended after 7 days to kill newly hatched mites. For lice, it may be applied to the affected area and left on for a shorter duration. Always follow your doctor's exact instructions. Do not use more often or for longer than prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 2 years of age due to the risk of neurotoxicity. For older children, the dose and duration must be determined by a doctor.
Elderly DosageElderly patients may be more susceptible to the neurotoxic effects of lindane. Use with caution and only under medical supervision. The dose and duration should be minimized, and the patient should be monitored for any neurological symptoms.
Renal ImpairmentNo specific dosage adjustments are established for renal impairment. However, since lindane is excreted renally, caution is advised in patients with significant renal disease. Consult a doctor for guidance.
Hepatic ImpairmentNo specific dosage adjustments are established for hepatic impairment. Lindane is metabolized in the liver, so caution is advised in patients with liver disease. Consult a doctor for guidance.
Maximum Daily DoseThe maximum daily dose is not applicable as this medicine is for topical use and is typically applied as a single application or according to a specific regimen. Do not exceed the prescribed frequency or duration.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled application
→ Apply as soon as you remember, unless it is almost time for the next application.
💡 Do not apply a double dose.
📌 If you miss the second application for scabies (day 7)
→ Apply it as soon as you remember, then resume the original schedule.
💡 If more than a few days have passed, consult your doctor.

⚠️ Side Effects of scabine lotion

✅ Common Side Effects

Skin irritation (Common (up to 10%))
Usually resolves without treatment. If persistent or severe, consult your doctor.
Redness (Common)
May be due to the medicine or the condition itself. Keep the area clean and avoid scratching.
Itching (Common)
Itching may continue for a few days after treatment due to dead mites. If it persists beyond 2 weeks, consult a doctor.
Burning sensation (Common)
Usually temporary. If severe, rinse the area with water and consult a doctor.

🚨 Serious Side Effects

Seizures (Rare (<0.1%))
Seek immediate medical attention if you experience convulsions, tremors, or unusual movements.
Dizziness (Rare)
Stop using the medicine and consult a doctor if you feel dizzy or lightheaded.
Severe allergic reaction (anaphylaxis) (Very rare)
Call emergency services if you have difficulty breathing, swelling of face, lips, or throat, or widespread rash.

⚠️ Rare Side Effects

Neurotoxicity
Report any neurological symptoms like confusion, headache, or muscle twitching to your doctor immediately.
Aplastic anemia
Seek medical attention if you experience unusual fatigue, bruising, or infections.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
Alcohol Moderate
Other topical lindane products Major

🚨 Major Interactions

  • Other topical products containing lindane or similar neurotoxic agents
  • CNS depressants (e.g., sedatives, alcohol)

⚡ Moderate Interactions

  • Anticoagulants (e.g., warfarin)
  • Hepatic enzyme inducers (e.g., rifampin, carbamazepine)

🍷 Alcohol Interaction

Alcohol should be avoided while using this medicine, especially if there is a possibility of systemic absorption of lindane, as it may increase the risk of central nervous system side effects such as dizziness or drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to lindane, cetrimide, or any component of the formulation.","Use on broken, inflamed, or infected skin.","Use in premature infants and children under 2 years of age.","Use in patients with uncontrolled seizure disorders.","Use in pregnant women (especially first trimester) and breastfeeding mothers unless clearly needed."]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes, mucous membranes, and open wounds.","Do not use on large areas of the body or for prolonged periods unless directed by a doctor.","Use with caution in children and elderly due to increased risk of neurotoxicity.","Do not apply to the face or genital area unless specifically instructed.","If accidental ingestion occurs, seek medical attention immediately.","Do not use if the packaging is damaged or if the product has expired.","Keep away from heat and open flames as the product may be flammable."]

🤱 Lactation Safety

Lindane is excreted in breast milk and may cause adverse effects in the nursing infant. It is not recommended for use during breastfeeding unless clearly needed. If used, avoid applying to the breast area to prevent infant exposure. Consult a doctor for alternative treatments.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical route, but if accidental ingestion occurs, it can cause serious neurotoxicity. Symptoms of overdose include dizziness, headache, nausea, vomiting, tremors, seizures, and respiratory depression. If ingestion is suspected, do not induce vomiting. Seek emergency medical attention immediately. Treatment is supportive and symptomatic, including management of seizures with appropriate anticonvulsants. Gastric lavage may be considered if ingestion occurred recently and the patient is stable.

⏰ Missed Dose

This medicine is usually applied as a single application or according to a specific schedule. If you miss a dose, apply it as soon as you remember, unless it is almost time for the next dose. Do not apply a double dose to make up for a missed one. Follow your doctor's instructions carefully.

Additional Safety Advice

General Safety

This medicine is for external use only. Do not swallow it or apply it to the eyes, inside the nose, mouth, or vagina. Avoid using it on broken, cut, or irritated skin unless specifically instructed by your doctor. Do not cover the treated area with tight bandages or clothing unless directed. Wash your hands thoroughly after applying the soap. Avoid contact with the eyes; if accidental contact occurs, rinse with plenty of water. Do not use this product for a longer period or more frequently than prescribed. Keep it out of reach of children. Pregnant women, breastfeeding mothers, and children should use this medicine only if clearly needed and under medical supervision. Do not share this medicine with others, even if they have similar symptoms. If you are using other topical products, consult your doctor before combining them. If symptoms persist or worsen after treatment, consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to the neurotoxic effects of lindane. Use this medicine with caution, at the lowest effective dose and for the shortest duration. Monitor for dizziness, confusion, or seizures.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, avoid using this medicine. Consult your doctor for safer alternatives to treat scabies or lice before conception.

🏥 Post-Surgery Considerations

Avoid using this medicine on surgical wounds or broken skin. Consult your doctor before using it after surgery.

🦷 Dental Procedures

No specific considerations for dental procedures. However, inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Maintain good personal hygiene to prevent reinfestation.
🥗
Wash all clothing and bedding in hot water during treatment.
😴
Avoid close physical contact with others until treatment is complete.
💧
Keep fingernails short to prevent scratching and secondary infection.
🧘
Use a moisturizer after treatment to soothe dry skin.
🌞
Follow up with your doctor to confirm eradication.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that cause excessive sweating immediately after applying this medicine, as sweating may reduce its effectiveness or cause irritation. Wait until the medicine has been washed off before resuming normal exercise.

🥗 Diet Recommendations

Stay well hydrated to support skin health.
Include foods rich in vitamin C and zinc to promote skin healing.
Avoid excessive sugar and processed foods that may worsen inflammation.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some individuals due to systemic absorption. Avoid driving or operating heavy machinery if you experience these effects. It is advisable to apply the medicine at bedtime to minimize interference with daily activities.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if you experience any serious side effects such as seizures, severe dizziness, or allergic reactions. Also stop if your condition does not improve after the full course of treatment, as you may need an alternative therapy.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to the risk of neurotoxicity from lindane accumulation. Prolonged or repeated use can lead to skin irritation, sensitization, and systemic absorption. If long-term therapy is required, regular monitoring for neurological symptoms and liver function may be advised. Always use the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Permethrin 5% cream

A safer and often more effective first-line treatment for scabies, suitable for pregnant women and children over 2 months.

Evidence: Well-established
Ivermectin oral

An oral antiparasitic effective for scabies, especially in institutional outbreaks or when topical treatment fails.

Evidence: Well-established
Benzyl benzoate lotion

An alternative topical treatment for scabies, though it can cause skin irritation.

Evidence: Established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you have a skin infection, consult your doctor before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep away from children and pets

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel, as lindane may be a controlled substance in some countries. Store it in a cool, dry place away from direct sunlight. If you need to apply it during travel, ensure you have access to a private area and follow the application instructions carefully. Time zone changes do not affect topical application schedules, but if you are on a specific regimen, adjust according to your doctor&#039;s advice.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old man with intense itching and rash between fingers
He was diagnosed with scabies and prescribed this medicine. He applied it as directed, left it on overnight, and washed it off in the morning. He also treated his family and washed all bedding. Within a week, the itching reduced significantly, and the rash cleared after a second application.
💡 Lesson: Proper application and treating all contacts are crucial to eliminate scabies and prevent recurrence.
👤 A 5-year-old child with lice infestation
The child's mother used this medicine on the child's scalp as prescribed. The lice were eliminated, but the child experienced mild scalp irritation that resolved in a few days. The doctor advised against using it again due to the child's age and recommended a safer alternative for future episodes.
💡 Lesson: This medicine can be effective but should be used with caution in young children due to potential neurotoxicity.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The medicine starts killing mites soon after application, but itching may persist for up to 2-4 weeks as it is often an allergic reaction to the dead mites. If symptoms persist beyond 4 weeks, consult your doctor.

Q: Can I use this soap every day?

A: No, this is a medicated soap and should only be used as prescribed, usually for a limited number of applications. Daily use can increase the risk of side effects.

Q: Is it safe to use during pregnancy?

A: It is not recommended during pregnancy unless clearly needed. Consult your doctor for safer alternatives like permethrin.

Q: What should I do if I miss a dose?

A: Apply it as soon as you remember, unless it is almost time for the next dose. Do not double dose.

Q: Can I drink alcohol while using this medicine?

A: It is best to avoid alcohol as it may increase the risk of dizziness or drowsiness if the medicine is absorbed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long should I leave it on?
  • Is it safe for my child?
  • Can I use it if I am pregnant?
  • What if I accidentally swallow it?
  • Will it cure scabies in one application?

🔄 Substitutes for scabine lotion

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Gamamed soap can be used for any skin infection.
    Fact: It is specifically for scabies and lice; it is not effective for fungal or most bacterial infections.
  • Myth: You can use gamamed soap daily for hygiene.
    Fact: It is a medicated soap and should only be used as prescribed for a limited time.
  • Myth: Gamamed soap is safe for babies.
    Fact: It is not recommended for children under 2 years due to risk of neurotoxicity.

🔄 Alternative Options

Generic Alternatives

  • Lindane 2% w/w + Cetrimide 0.5% w/w soap

Brand Alternatives

  • Gamamed Soap

📊 Comparison with Similar Medicines

[{"medicine":"Permethrin 5% cream","class":"Pyrethroid","route":"Topical","efficacy":"First-line for scabies","safety":"Generally safe, including in pregnancy and children >2 months"},{"medicine":"Ivermectin oral","class":"Antiparasitic","route":"Oral","efficacy":"Effective for scabies","safety":"Not for children <15 kg, pregnancy category C"},{"medicine":"Benzyl benzoate lotion","class":"Acaricide","route":"Topical","efficacy":"Effective but can be irritating","safety":"Not for children <2 years"}]

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