savmox 500mg/125 mg tablet - Amoxycillin (500mg) + Clavulanic Acid (125 mg) medicine

Savmox 500mg/125mg Tablet: Complete Medicine Guide

No reviews yet
🏭 Saviour Speciality Drugs Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is savmox 500mg/125 mg tablet used for?

This medicine is a combination antibiotic containing amoxycillin and clavulanic acid. It is used to treat bacterial infections such as respiratory, urinary, skin, and dental infections. It works by killing bacteria and preventing their resistance.

  • Generic Name: Amoxycillin (500mg) + Clavulanic Acid (125 mg)
  • Manufacturer: Saviour Speciality Drugs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 savmox 500mg/125 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एमोक्सिसिलिन और क्लैवुलैनिक एसिड का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह श्वसन तंत्र, मूत्र मार्ग, त्वचा और दांतों के संक्रमण में प्रभावी है। यह बैक्टीरिया को मारती है और उनके प्रतिरोध को रोकती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, उल्टी, त्वचा पर चकत्ते और खुजली शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, यकृत की समस्या और गंभीर त्वचा प्रतिक्रियाएं शामिल हो सकती हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को पेनिसिलिन एलर्जी के बारे में बताएं। अन्य दवाओं के साथ इसके परस्पर प्रभाव की जानकारी दें। इसे भोजन के साथ लें। शराब से बचें। पूरा कोर्स पूरा करें। यदि खुराक छूट जाए तो याद आते ही लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 savmox 500mg/125 mg tablet Uses & Benefits

  • [{"condition":"Respiratory tract infections","description":"Used to treat community-acquired pneumonia, acute bacterial sinusitis, and acute exacerbations of chronic bronchitis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated and complicated urinary tract infections caused by susceptible strains of E.
  • coli, Klebsiella, and Enterobacter.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and pericoronitis caused by susceptible oral bacteria.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"May be used for osteomyelitis and septic arthritis caused by susceptible organisms, often in combination with surgical drainage.","evidence":"Established"}]

Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes used as part of a combination regimen to eradicate H. pylori in peptic ulcer disease.","evidence":"Limited"},{"condition":"Lyme disease","description":"May be used off-label for early Lyme disease in patients who cannot take doxycycline.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Urinary tract infections, Skin infections, Dental infections

📋 Drug Information

Generic Name(s)Amoxycillin (500mg) + Clavulanic Acid (125 mg)
Brand Namesavmox 500mg/125 mg tablet
ManufacturerSaviour Speciality Drugs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place away from direct sunlight. Do not refrigerate. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if you feel better.
3
Do not share this medicine with others.
4
Inform your doctor if you are allergic to penicillin.
5
Avoid alcohol while taking this medicine.
6
Report any unusual bleeding or bruising immediately.
7
Stay well hydrated throughout the day.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough
This medicine is commonly prescribed for respiratory infections.
Likely Use
✅
Burning urination
This medicine is used for urinary tract infections.
Likely Use
❌
Runny nose
This medicine is not for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmoxycillin and clavulanic acid are well absorbed from the gastrointestinal tract after oral administration. Food does not significantly affect the absorption of amoxycillin but may improve tolerance. Peak plasma concentrations are achieved within 1 to 2 hours.
DistributionBoth components distribute widely into body tissues and fluids, including lungs, middle ear, sinus, skin, and urine. Amoxycillin penetrates cerebrospinal fluid only when meninges are inflamed. Clavulanic acid also distributes into various tissues but to a lesser extent.
Protein BindingAmoxycillin is approximately 17-20% bound to plasma proteins. Clavulanic acid is about 22-30% bound.
MetabolismAmoxycillin is partially metabolized to inactive penicilloic acid. Clavulanic acid is extensively metabolized in the liver to inactive metabolites.
Half-LifeThe elimination half-life of amoxycillin is approximately 1 to 1.5 hours. Clavulanic acid has a half-life of about 1 hour. Both are prolonged in renal impairment.
ExcretionAmoxycillin is primarily excreted unchanged in the urine via glomerular filtration and tubular secretion. Clavulanic acid is excreted in urine and feces, with about 25-40% excreted unchanged in urine.
BioavailabilityThe oral bioavailability of amoxycillin is approximately 70-90%. Clavulanic acid bioavailability is about 60-75%.
Onset of ActionAntibacterial effects begin within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimePeak plasma concentrations are reached 1 to 2 hours after oral administration.
Duration of ActionThe antibacterial effect lasts approximately 6 to 8 hours, depending on the dose and renal function.

How It Works

This medicine combines amoxycillin, a beta-lactam antibiotic, with clavulanic acid, a beta-lactamase inhibitor. Amoxycillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial cell death. Clavulanic acid irreversibly inhibits beta-lactamase enzymes produced by certain bacteria, thereby protecting amoxycillin from degradation and extending its spectrum of activity against beta-lactamase-producing organisms.

Mechanism Steps

1
Binding to penicillin-binding proteins: Amoxycillin binds to penicillin-binding proteins on the bacterial cell membrane, inhibiting the cross-linking of peptidoglycan chains in the cell wall.
2
Inhibition of cell wall synthesis: This inhibition weakens the bacterial cell wall, leading to cell lysis and death, especially in actively dividing bacteria.
3
Protection by clavulanic acid: Clavulanic acid binds irreversibly to beta-lactamase enzymes, preventing them from hydrolyzing amoxycillin, thus preserving its antibacterial activity.
4
Extended spectrum: The combination extends amoxycillin's activity to include many beta-lactamase-producing bacteria that would otherwise be resistant.

💡 How to Take savmox 500mg/125 mg tablet

Strength: Tablet containing 500 mg amoxycillin and 125 mg clavulanic acid.

1Take this medicine orally with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.
6Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose is one tablet of 500 mg/125 mg taken orally every 8 hours (three times a day) or every 12 hours (twice a day) depending on the severity of infection. For severe infections, the dose may be increased. The duration of treatment varies by indication, typically 5 to 14 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on weight and indication.
Elderly DosageElderly patients may have reduced renal function; dose adjustment may be necessary based on creatinine clearance. Monitor renal function closely.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. For creatinine clearance 10-30 mL/min, the usual dose is 500 mg/125 mg every 12 hours. For creatinine clearance less than 10 mL/min, 500 mg/125 mg every 24 hours. For hemodialysis patients, one dose during and one dose after dialysis. Consult a clinician for precise dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Monitor liver function tests. Dose adjustment may be needed. Consult a clinician.
Maximum Daily DoseThe maximum recommended daily dose is 1500 mg amoxycillin/375 mg clavulanic acid (three 500/125 mg tablets per day). For severe infections, higher doses may be used under medical supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No restriction
No significant interaction.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of savmox 500mg/125 mg tablet

✅ Common Side Effects

Diarrhoea (Common (5-10%))
Stay hydrated. If diarrhoea is severe or persistent, consult your doctor.
Nausea (Common (3-5%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (1-3%))
Take with food and avoid large meals. Consult doctor if vomiting continues.
Skin rash (Common (1-3%))
Stop the medicine and consult your doctor immediately if rash appears.
Itching (Uncommon (0.1-1%))
May be a sign of allergy. Consult your doctor if itching occurs.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately if you experience difficulty breathing, swelling of face or throat, or severe dizziness.
Hepatitis (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Clostridium difficile-associated diarrhoea (Rare (<0.1%))
Seek medical attention if you develop severe, watery, or bloody diarrhoea, even weeks after stopping the antibiotic.
Stevens-Johnson syndrome (Very rare (<0.01%))
Seek immediate medical care if you develop a painful rash with blisters, peeling skin, or sores in the mouth or eyes.

⚠️ Rare Side Effects

Agranulocytosis
Report unusual tiredness, fever, or sore throat to your doctor.
Thrombocytopenia
Report easy bruising or bleeding to your doctor.
Interstitial nephritis
Report decreased urine output or swelling to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Allopurinol Moderate
Oral contraceptives Moderate
Probenecid Moderate
Mycophenolate mofetil Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Allopurinol

⚡ Moderate Interactions

  • Oral contraceptives
  • Probenecid
  • Mycophenolate mofetil

🍷 Alcohol Interaction

Alcohol may worsen gastrointestinal side effects such as nausea and vomiting. It is advisable to avoid alcohol while taking this medicine, especially if you have liver disease.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to amoxycillin, clavulanic acid, or any penicillin","History of severe allergic reaction to beta-lactam antibiotics","Previous history of cholestatic jaundice/hepatic dysfunction associated with this combination"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with hepatic impairment; monitor liver function.","May cause Clostridium difficile-associated diarrhoea; if suspected, discontinue and treat appropriately.","May reduce effectiveness of oral contraceptives; use additional contraception.","Serious allergic reactions can occur; discontinue immediately if suspected.","Prolonged use may lead to fungal or bacterial superinfections.","Not effective against viral infections."]

🤱 Lactation Safety

Amoxycillin and clavulanic acid are excreted in breast milk in small amounts. This medicine is generally considered safe during breastfeeding, but monitor the infant for diarrhoea, thrush, or rash. Consult your doctor before use.

💊 Overdose Management

Overdose may cause gastrointestinal symptoms such as nausea, vomiting, and diarrhoea. In severe cases, fluid and electrolyte imbalance may occur. Treatment is symptomatic and supportive. Hemodialysis may be considered in patients with renal failure. Contact a poison control center or emergency department immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you are allergic to penicillin or any other antibiotics. Tell your doctor about all other medicines you are taking, especially blood thinners like warfarin, allopurinol, and methotrexate. This medicine may reduce the effectiveness of oral contraceptives, so use additional contraception if needed. Avoid alcohol while taking this medicine as it may worsen stomach upset and liver effects. Take this medicine with food to reduce stomach discomfort. Do not share this medicine with others, even if they have similar symptoms. Complete the full prescribed course. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and are at higher risk of side effects. Dose adjustment may be necessary. Monitor renal and liver function closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe during pregnancy but should be used only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions regarding dosing and duration.

🦷 Dental Procedures

This medicine may be prescribed before or after dental procedures to prevent or treat infection. Inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated.
🥗
Get adequate rest.
😴
Eat a balanced diet.
💧
Practice good hygiene.
🧘
Avoid close contact with sick individuals.

🏋️ Exercise Considerations

If you experience dizziness or fatigue, avoid strenuous exercise until you feel better. Consult your doctor before resuming intense workouts.

🥗 Diet Recommendations

Include probiotics like yogurt to prevent diarrhoea.
Stay well hydrated.
Avoid alcohol.
Eat light, easily digestible meals.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you experience these effects. It is generally safe to continue normal daily activities as tolerated.

🛑 When to Stop This Medicine

Stop taking this medicine only after completing the full prescribed course or as directed by your doctor. Do not stop early even if you feel better, as this can lead to recurrence and resistance. If you experience serious side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance, fungal or bacterial superinfections, and rarely liver or kidney problems. It should only be used for the prescribed duration. Regular monitoring may be required if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help prevent antibiotic-associated diarrhoea.

Evidence: Well-established
Symptomatic treatment

For viral infections, rest and fluids are recommended instead of antibiotics.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled for a vaccine, inform your doctor about your current antibiotic treatment.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying antibiotics.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with a persistent cough and fever
Started this medicine as prescribed for a respiratory tract infection. Within 3 days, fever subsided and cough improved. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with a urinary tract infection
Took this medicine for 7 days as prescribed. Symptoms resolved completely. She was advised to complete the course to prevent recurrence.
💡 Lesson: Completing the full course is essential to prevent antibiotic resistance and recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2 to 3 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, taking it with food helps reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full prescribed course to prevent recurrence and resistance.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people allergic to penicillin or with certain liver conditions.

🔄 Alternative Options

Generic Alternatives

  • Amoxycillin and Clavulanic Acid 500 mg/125 mg Tablet

Brand Alternatives

  • Augmentin 500mg/125mg Tablet
  • Clavam 500mg/125mg Tablet
  • Moxikind-CV 500mg/125mg Tablet
  • Advent 500mg/125mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Amoxycillin 500mg + Clavulanic Acid 125mg","class":"Beta-lactam antibiotic + beta-lactamase inhibitor","primary_use":"Broad-spectrum bacterial infections"},{"medicine":"Amoxycillin alone","composition":"Amoxycillin 500mg","class":"Beta-lactam antibiotic","primary_use":"Susceptible bacterial infections"},{"medicine":"Azithromycin","composition":"Azithromycin 500mg","class":"Macrolide antibiotic","primary_use":"Respiratory and skin infections"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory