Aztric CT 12.5 Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, throat, or tongue
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Chest pain or irregular heartbeat
- Decreased urine output or swelling in legs
- Severe abdominal pain or vomiting
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is sartoj-ct tablet used for?
This medicine is a combination of azilsartan medoxomil and chlorthalidone used to treat high blood pressure. It works by relaxing blood vessels and removing excess fluid from the body. It is taken orally once daily.
- Generic Name: Azilsartan medoxomil (40mg) + Chlorthalidone (12.5mg)
- Manufacturer: Ojal Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sartoj-ct tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह एज़िलसार्टन मेडोक्सोमिल और क्लोर्थालिडोन का संयोजन है। यह रक्त वाहिकाओं को आराम देकर और शरीर से अतिरिक्त नमक और पानी को बाहर निकालकर रक्तचाप को कम करती है। यह आमतौर पर दिन में एक बार मौखिक रूप से ली जाती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और बार-बार पेशाब आना शामिल हैं। कुछ रोगियों में पोटेशियम या सोडियम की कमी हो सकती है, जिससे मांसपेशियों में ऐंठन या कमजोरी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन चेहरे, होंठ, गले या जीभ में सूजन (एंजियोएडेमा) हो सकती है। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को गर्भावस्था, स्तनपान या अन्य दवाओं के बारे में बताएं। गर्भावस्था में यह दवा नुकसानदायक हो सकती है, इसलिए इसे न लें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। अचानक उठने से बचें। पर्याप्त पानी पिएं। डॉक्टर के बताए अनुसार नियमित जांच कराएं। दवा को अचानक बंद न करें।
💊 sartoj-ct tablet Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is used to treat high blood pressure in adults when a single agent is not effective.
- It helps reduce blood pressure and lowers the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Hypertension
Also treats: Heart failure, Chronic kidney disease, Diabetes mellitus, Metabolic syndrome
📋 Drug Information
| Generic Name(s) | Azilsartan medoxomil (40mg) + Chlorthalidone (12.5mg) |
| Brand Name | sartoj-ct tablet |
| Manufacturer | Ojal Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place away from direct sunlight. Do not refrigerate. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Azilsartan medoxomil is an angiotensin II receptor blocker (ARB) that selectively blocks the AT1 receptor subtype, preventing angiotensin II from exerting its vasoconstrictor and aldosterone-secreting effects. This leads to relaxation of blood vessels and reduced blood pressure. Chlorthalidone is a thiazide-like diuretic that inhibits sodium reabsorption in the distal convoluted tubule of the kidney, increasing excretion of sodium, chloride, and water. This reduces plasma volume and cardiac output initially, and later reduces peripheral vascular resistance. Together, these agents lower blood pressure more effectively than either alone.
Mechanism Steps
💡 How to Take sartoj-ct tablet
Strength: Azilsartan medoxomil 40 mg and chlorthalidone 12.5 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet (azilsartan medoxomil 40 mg and chlorthalidone 12.5 mg) taken orally once daily, with or without food. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. The maximum recommended dose is one tablet of azilsartan medoxomil 40 mg and chlorthalidone 25 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustment is required for elderly patients based on age alone. However, elderly patients may be more sensitive to the blood pressure-lowering effects and electrolyte imbalances. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dosage adjustment is necessary for patients with mild to moderate renal impairment (creatinine clearance 30-89 mL/min). In patients with severe renal impairment (creatinine clearance <30 mL/min), use is not recommended. Monitor kidney function regularly. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No dosage adjustment is necessary for patients with mild to moderate hepatic impairment. Use in patients with severe hepatic impairment is not recommended. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is azilsartan medoxomil 40 mg and chlorthalidone 25 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sartoj-ct tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aliskiren | Major | |
| Lithium | Major | |
| NSAIDs | Major | |
| Potassium-sparing diuretics | Major | |
| Digoxin | Major | |
| Corticosteroids | Moderate | |
| Antidiabetics | Moderate | |
| Cholestyramine | Moderate | |
| Antacids | Minor | |
| Alcohol | Minor |
🚨 Major Interactions
- Aliskiren
- Lithium
- Potassium-sparing diuretics (e.g., spironolactone)
- NSAIDs (e.g., ibuprofen, naproxen)
- Digoxin
⚡ Moderate Interactions
- Corticosteroids
- Other antihypertensives
- Antidiabetic drugs
- Cholestyramine
🍷 Alcohol Interaction
Alcohol can enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and increased risk of fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Anuria (absence of urine production)","Hypersensitivity to azilsartan, chlorthalidone, or any component of the formulation","History of angioedema related to ARB therapy","Concomitant use with aliskiren in patients with diabetes","Severe hepatic impairment","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine can cause fetal harm when administered to a pregnant woman. Discontinue as soon as pregnancy is detected.","May cause symptomatic hypotension, especially in volume-depleted patients. Correct volume depletion before starting therapy.","Monitor renal function periodically. Deterioration may occur in patients with pre-existing kidney disease.","Chlorthalidone can cause electrolyte imbalances. Monitor electrolytes regularly.","May increase blood glucose and cholesterol levels. Monitor in patients with diabetes or dyslipidemia.","Avoid use in patients with a history of angioedema.","Use with caution in patients with severe heart failure or aortic/mitral stenosis.","Do not use in patients with anuria.","May cause photosensitivity. Advise patients to use sun protection."]
🤱 Lactation Safety
Not established from the available information. It is not known whether azilsartan or chlorthalidone are excreted in human breast milk. Because of the potential for adverse effects in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose may cause severe hypotension, electrolyte imbalances, and dehydration. If overdose is suspected, contact a poison control center or emergency room immediately. Treatment is supportive and symptomatic. Induce vomiting if the patient is conscious and within 1-2 hours of ingestion. Administer intravenous fluids for hypotension. Monitor electrolytes and kidney function closely. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine can harm an unborn baby, so it is not recommended during pregnancy. Do not breastfeed while taking this medicine, as it may pass into breast milk and affect the baby. Tell your doctor about all other medications you are taking, especially other blood pressure medicines, diuretics, lithium, or nonsteroidal anti-inflammatory drugs (NSAIDs). Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Stand up slowly from a sitting or lying position to prevent falls due to dizziness. Drink adequate fluids to prevent dehydration, especially in hot weather or during exercise. Your doctor will monitor your blood pressure, kidney function, and electrolyte levels regularly. Do not stop taking this medicine suddenly without consulting your doctor, as this can cause your blood pressure to rise dangerously. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects and electrolyte imbalances caused by this medicine. Start with a lower dose and monitor closely. Regular monitoring of kidney function and electrolytes is important. Falls due to dizziness should be prevented.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine. If you become pregnant, stop the medicine immediately and contact your doctor.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to the risk of hypotension. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or increase the risk of bleeding. Your dentist may need to take precautions. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine, but you may experience dizziness or lightheadedness, especially when starting treatment or after intense exercise. Stay hydrated and avoid sudden changes in position. If you feel dizzy during exercise, stop and rest. Consult your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Take the medicine in the morning to minimize nighttime urination. Most people can continue their normal work and daily activities with appropriate precautions.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as angioedema, severe hypotension, or kidney problems, seek immediate medical attention. Your doctor may adjust the dose or switch to a different medicine if needed.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of kidney function, electrolytes, and blood glucose levels. It can cause electrolyte imbalances, especially low potassium and sodium. In some patients, it may increase blood sugar and cholesterol levels. Regular follow-up with your doctor is essential to adjust the dose and manage any side effects. The medicine is generally safe for long-term use when monitored appropriately.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, calcium channel blockers, or beta-blockers may be alternatives if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before receiving any vaccine. Keep your vaccinations up to date, especially influenza and pneumococcal vaccines, as recommended for patients with hypertension.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule. Carry enough supply for your entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1-2 hours, but the full effect may take 2-4 weeks of regular use.
A: Yes, you can take it with or without food. Taking it at the same time each day is important.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, this medicine is not recommended during pregnancy as it can harm the unborn baby. Consult your doctor immediately if you become pregnant.
A: No, do not stop taking this medicine without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause a dangerous rise.
🤔 Common Patient Concerns
🔄 Substitutes for sartoj-ct tablet
View AllAlternative brands with exact same active ingredient:
-
arbozil-ct 40/12.5 tabletZuventus Healthcare Ltd ₹102.19 6.2% CHEAPER
-
macarbi ch 40mg/12.5mg tabletMacleods Pharmaceuticals Pvt Ltd ₹102.19 6.2% CHEAPER
-
nexsart ch 40mg/12.5mg tabletMacleods Pharmaceuticals Pvt Ltd ₹102.19 6.2% CHEAPER
-
zilokem ct 40/12.5 tabletAlkem Laboratories Ltd ₹112.03 2.8% COSTLIER
-
zilatax ct 40mg/12.5mg tabletAjanta Pharma Ltd ₹119.25 9.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping the medicine can cause a dangerous rise. Continue as prescribed. - Myth: This medicine causes kidney damage in everyone.
Fact: Kidney function is monitored, and the medicine can actually protect kidneys in some patients. Unmonitored use may pose risks. - Myth: You can eat salty foods as long as you take this medicine.
Fact: High salt intake can counteract the blood pressure-lowering effect. A low-sodium diet is recommended.
🔄 Alternative Options
Generic Alternatives
- Azilsartan medoxomil + Chlorthalidone (generic)
Brand Alternatives
- Azilva CT
- Azilsartan CT
- Zilsartan CT