sardinil p syrup - Guaifenesin (50mg) + Chlorpheniramine Maleate (2mg) medicine

Inkuf-D Syrup: Complete Medicine Guide

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🏭 Dial Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for combination.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swallowing
  • Swelling of face, lips, tongue, or throat
  • Seizures or convulsions
  • Fast, irregular, or pounding heartbeat
  • Severe drowsiness or confusion
  • Inability to urinate
  • Blood in sputum or severe chest pain

If experiencing severe symptoms, call emergency services immediately.

What is sardinil p syrup used for?

This medicine is a combination of guaifenesin (expectorant) and chlorpheniramine (antihistamine) used to relieve cough, congestion, and allergic symptoms. It works by thinning mucus and blocking histamine. It may cause drowsiness, so avoid driving. Take as prescribed by your doctor.

  • Generic Name: Guaifenesin (50mg) + Chlorpheniramine Maleate (2mg)
  • Manufacturer: Dial Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 sardinil p syrup के बारे में (Hindi Summary)

उपयोग: यह दवा गुआइफेनेसिन और क्लोरफेनिरामाइन मेलिएट का संयोजन है। इसका उपयोग खांसी, जुकाम, और एलर्जी के लक्षणों जैसे बहती नाक, छींक और गले में खुजली से राहत दिलाने के लिए किया जाता है। यह बलगम को पतला करके खांसी को आसान बनाती है और एलर्जी को कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, जी मिचलाना और धुंधली दृष्टि शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, पेशाब में रुकावट, दिल की धड़कन तेज होना, दौरे पड़ना हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। दवा लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब न लें। अगर आपको ग्लूकोमा, पेशाब में रुकावट, लीवर या किडनी की बीमारी है तो डॉक्टर को बताएं। बच्चों को डॉक्टर की सलाह के बिना न दें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 sardinil p syrup Uses & Benefits

[{"condition":"Productive cough","description":"Helps loosen mucus and relieve chest congestion associated with common cold or mild respiratory infections.","evidence":"Well-established for guaifenesin; chlorpheniramine provides additional relief from runny nose and sneezing."},{"condition":"Allergic rhinitis","description":"Reduces sneezing, runny nose, and itching of the nose or throat due to allergies.","evidence":"Well-established for chlorpheniramine."},{"condition":"Common cold","description":"Provides symptomatic relief from cough, nasal congestion, and sneezing.","evidence":"Commonly used, but evidence for combination is limited."}]

Off-label uses: []

Primary treatment for: Cough and cold

Also treats: Allergic rhinitis, Productive cough

📋 Drug Information

Generic Name(s)Guaifenesin (50mg) + Chlorpheniramine Maleate (2mg)
Brand Namesardinil p syrup
ManufacturerDial Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Stay well hydrated to help loosen mucus.
3
Avoid alcohol and other sedatives while taking this medicine.
4
Do not use for chronic cough or cough with excessive phlegm without medical advice.
5
Consult your doctor if symptoms persist beyond 7 days or worsen.
6
Keep out of reach of children and use a proper measuring device.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough
This medicine is commonly prescribed for this.
Likely Use
✅
Runny nose
Chlorpheniramine helps reduce runny nose.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionGuaifenesin is rapidly absorbed from the gastrointestinal tract. Chlorpheniramine is also well absorbed after oral administration.
DistributionGuaifenesin is distributed widely throughout the body. Chlorpheniramine is distributed widely, including into the central nervous system.
Protein BindingGuaifenesin: Not established from the available information. Chlorpheniramine: Approximately 70% bound to plasma proteins.
MetabolismGuaifenesin is metabolized in the liver. Chlorpheniramine is metabolized in the liver, primarily by CYP2D6 and CYP3A4.
Half-LifeGuaifenesin: Approximately 1 hour. Chlorpheniramine: Approximately 12-15 hours.
ExcretionGuaifenesin is excreted primarily in the urine. Chlorpheniramine is excreted in the urine as unchanged drug and metabolites.
BioavailabilityGuaifenesin: Not established from the available information. Chlorpheniramine: Approximately 25-50%.
Onset of ActionGuaifenesin: Within 30 minutes. Chlorpheniramine: Within 30-60 minutes.
Peak Plasma TimeGuaifenesin: Approximately 1 hour. Chlorpheniramine: Approximately 2-3 hours.
Duration of ActionGuaifenesin: 4-6 hours. Chlorpheniramine: 4-6 hours.

How It Works

Guaifenesin is an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions, promoting ciliary action and facilitating the removal of mucus. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing allergic symptoms such as sneezing, rhinorrhea, and itching. It also has anticholinergic properties that contribute to drying of respiratory secretions.

Mechanism Steps

1
Guaifenesin action: Guaifenesin is thought to stimulate the gastric mucosa, leading to a reflex increase in respiratory tract fluid secretion, which thins mucus and makes it easier to cough up.
2
Chlorpheniramine action: Chlorpheniramine competitively blocks histamine at H1 receptor sites, preventing histamine-induced sneezing, runny nose, and itching. It also has anticholinergic effects that reduce secretions.

💡 How to Take sardinil p syrup

Strength: Each 5 mL contains Guaifenesin 50 mg and Chlorpheniramine Maleate 2 mg.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take orally with or without food.
4Follow the prescribed dose and duration.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 5-10 mL (1-2 teaspoons) every 4-6 hours as needed, not to exceed 6 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of chlorpheniramine, especially drowsiness and anticholinergic effects. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor.
Maximum Daily DoseMaximum daily dose for adults: 60 mL (12 teaspoons) in 24 hours. Do not exceed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of sardinil p syrup

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Nausea (Common (5-10%))
Take with food or milk. Consult doctor if persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing.
Urinary retention (Rare (<0.1%))
Consult doctor immediately if you are unable to urinate.
Seizures (Rare (<0.1%))
Seek emergency medical help if seizures occur.
Fast or irregular heartbeat (Rare (<0.1%))
Contact doctor immediately if you notice palpitations or irregular pulse.

⚠️ Rare Side Effects

Hallucinations
Seek immediate medical attention.
Blood dyscrasias
Report unusual bleeding or bruising to doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
CNS depressants Major
Anticholinergics Moderate
CYP2D6 inhibitors Moderate
Alcohol Moderate

🚨 Major Interactions

  • MAO inhibitors
  • CNS depressants (alcohol, benzodiazepines, opioids)

⚡ Moderate Interactions

  • Anticholinergics (e.g., atropine, tricyclic antidepressants)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

🍷 Alcohol Interaction

Avoid alcohol consumption while taking this medicine as it can increase drowsiness and impair your ability to drive or operate machinery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to guaifenesin or chlorpheniramine","Narrow-angle glaucoma","Urinary retention","Severe liver disease","Asthma (for chlorpheniramine)","MAO inhibitor therapy within 14 days"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, prostatic hypertrophy, or urinary retention.","Not recommended for children under 6 years without medical advice.","Consult doctor if cough persists more than 7 days or is accompanied by fever, rash, or persistent headache.","Do not exceed recommended dose."]

🤱 Lactation Safety

Guaifenesin and chlorpheniramine are excreted in breast milk. Caution is advised; consult your doctor before use.

💊 Overdose Management

Overdose may cause severe drowsiness, seizures, respiratory depression, and anticholinergic effects. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Avoid alcohol and other central nervous system depressants while taking this medicine. Inform your doctor if you have glaucoma, prostate enlargement, urinary retention, liver or kidney disease, or asthma. Do not use this medicine for a chronic cough or cough with a lot of mucus without consulting a doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and anticholinergic effects of chlorpheniramine. Use with caution and lower doses may be needed. Consult a doctor.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with anesthetics and other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to ease breathing.
😴
Avoid allergens and irritants like smoke.
💧
Get plenty of rest to support recovery.
🧘
Practice good hand hygiene to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel drowsy or dizzy. Light activity is fine if you feel up to it.

🥗 Diet Recommendations

Drink warm fluids like soups and teas.
Avoid cold drinks and ice cream.
Include vitamin C rich fruits.
Avoid spicy and oily foods if you have a sore throat.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also reduce alertness, so take caution during work.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of chlorpheniramine may lead to tolerance and dependence. Regular monitoring of liver and kidney function may be advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal spray

Moisturizes nasal passages and reduces congestion.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with common cold and productive cough
He was prescribed this medicine for his cough and congestion. He took it as directed and noticed relief within a day. He experienced mild drowsiness, so he avoided driving. He recovered fully in 5 days.
💡 Lesson: Taking the medicine as prescribed and avoiding driving when drowsy ensures safety and effectiveness.
👤 A 28-year-old woman with allergic rhinitis
She used this medicine for sneezing and runny nose during allergy season. It helped control her symptoms, but she felt sleepy during the day. She switched to taking it at night after consulting her doctor.
💡 Lesson: Timing the dose to minimize daytime drowsiness can improve adherence and quality of life.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after taking a dose.

Q: Can I take it at night?

A: Yes, but it may cause drowsiness. It is often taken at night to help with sleep while relieving symptoms.

Q: Is it safe for children?

A: It is not recommended for children under 6 years without medical advice. Consult a pediatrician for appropriate dosing.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for sardinil p syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: It is effective only for productive cough and allergic symptoms. It is not for dry cough or chronic cough without medical advice.
  • Myth: It is safe to take extra doses for faster relief.
    Fact: Taking more than the recommended dose can lead to serious side effects like severe drowsiness, seizures, and heart problems.

📊 Comparison with Similar Medicines

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